Comparison between polyvinylpyrrolidone and silica nanoparticles as carriers for indomethacin in a solid state dispersion

International Journal of Pharmaceutics

Volumn 250, Issue 1, 2003, Pages 283-286

  Watanabe, Tomoyuki ^a   Hasegawa, Susumu ^a   Wakiyama, Naoki ^a   Kusai, Akira ^a   Senna, Mamoru ^b  

^a DAIICHI SANKYO CO   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

Co grinding; Indomethacin; Interaction; Polyvinylpyrrolidone; Solid state NMR

Indexed keywords

AMIDE; CARBON; CARBONYL DERIVATIVE; CARBOXYL GROUP; DRUG CARRIER; INDOMETACIN; KOLLIDON 90F; NANOPARTICLE; POVIDONE; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COMPARATIVE STUDY; DISPERSION; DRUG SOLUBILITY; GRINDING; HYDROGEN BOND; MOLECULAR INTERACTION; NUCLEAR MAGNETIC RESONANCE; PREDICTION; PRIORITY JOURNAL; SOLID STATE; CHEMISTRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

DRUG CARRIERS; INDOMETHACIN; MAGNETIC RESONANCE SPECTROSCOPY; POVIDONE; SILICON DIOXIDE;

EID: 0037413412     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(02)00549-5     Document Type: Article

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