Acute hypoxia affects P-TEFb through HDAC3 and HEXIM1-dependent mechanism to promote gene-specific transcriptional repression

Nucleic Acids Research

Volumn 42, Issue 14, 2014, Pages 8954-8969

  Safronova, Olga S ^a   Nakahama, Ken Ichi ^a   Morita, Ikuo ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 9; CYCLIN T1; HEXIM1 PROTEIN; HISTONE DEACETYLASE 3; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; NUCLEAR RECEPTOR COREPRESSOR; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; REGULATOR PROTEIN; RNA POLYMERASE II; SERINE; SERINE 2; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS; CHROMATIN ASSEMBLY AND DISASSEMBLY; COMPLEX FORMATION; CONTROLLED STUDY; DEACETYLATION; EQUILIBRIUM CONSTANT; GENE EXPRESSION PROFILING; GENE LOCATION; GENE REPRESSION; GENE TRANSLOCATION; GENETIC TRANSCRIPTION; HELA CELL LINE; HISTONE ACETYLATION; HUMAN; HUMAN CELL; HYPOXIA; HYPOXIC CELL; IL 8 GENE; INHIBITION KINETICS; INTRACELLULAR SIGNALING; MCP 1 GENE; MESSENGER RNA SYNTHESIS; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SUBUNIT; TRANSCRIPTION ELONGATION; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS;

ACETYLATION; ACTIVE TRANSPORT, CELL NUCLEUS; CELL HYPOXIA; CELL NUCLEUS; CHEMOKINE CCL2; CYCLIN T; CYCLIN-DEPENDENT KINASE 9; GENE EXPRESSION REGULATION; HELA CELLS; HISTONE DEACETYLASES; HUMANS; NUCLEAR RECEPTOR CO-REPRESSOR 1; PHOSPHORYLATION; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; RNA, MESSENGER; RNA-BINDING PROTEINS; SERINE; TRANSCRIPTION ELONGATION, GENETIC; TRANSCRIPTOME;

EID: 84906271437     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku611     Document Type: Article

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