Urinary concentrations of phthalates in couples planning pregnancy and its association with 8-hydroxy-2′-deoxyguanosine, a biomarker of oxidative stress: Longitudinal investigation of fertility and the environment study

Environmental Science and Technology

Volumn 48, Issue 16, 2014, Pages 9804-9811

  Guo, Ying ^a   Weck, Jennifer ^b   Sundaram, Rajeswari ^b   Goldstone, Alexandra E ^c   Buck Louis, Germaine ^b   Kannan, Kurunthachalam ^a,d  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c GEORGE WASHINGTON UNIVERSITY   (United States)

^d KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; ENVIRONMENTAL PROTECTION AGENCY; METABOLITES; OBSTETRICS; OXIDATIVE STRESS; POTASSIUM COMPOUNDS;

DI-2-ETHYLHEXYL PHTHALATE; ENVIRONMENTAL CHEMICALS; ESTIMATED DAILY INTAKES; MEDIAN CONCENTRATION; MONOMETHYL PHTHALATE; PHTHALATE EXPOSURES; PHTHALATE METABOLITES; U.S. ENVIRONMENTAL PROTECTION AGENCY;

ESTERS;

8 HYDROXYDEOXYGUANOSINE; BIOLOGICAL MARKER; CREATININE; MONO (2 ISOBUTYL)PHTHALATE; MONO (3 CARBOXYPROPYL)PHTHALATE; MONO N BUTYL PHTHALATE; MONOBENZYL PHTHALATE; MONOMETHYL PHTHALATE; PHTHALIC ACID BIS(2 ETHYLHEXYL) ESTER; PHTHALIC ACID DERIVATIVE; PHTHALIC ACID DIMETHYL ESTER; PHTHALIC ACID ETHYL ESTER; UNCLASSIFIED DRUG; 8-OXO-7-HYDRODEOXYGUANOSINE; DEOXYGUANOSINE; PHTHALIC ACID;

BIOMARKER; CONCENTRATION (COMPOSITION); HEALTH RISK; INFERTILITY; METABOLITE; PHTHALATE; POLLUTION EXPOSURE; PREGNANCY; SAMPLING; URINE;

ADULT; ARTICLE; CREATININE URINE LEVEL; ENVIRONMENTAL EXPOSURE; FAMILY PLANNING; FEMALE; FEMALE FERTILITY; HUMAN; KIDNEY CONCENTRATING CAPACITY; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MALE FERTILITY; OXIDATIVE STRESS; PREGNANCY; SEX DIFFERENCE; UNITED STATES; URINALYSIS; URINE VOLUME; ADOLESCENT; ANALOGS AND DERIVATIVES; ENVIRONMENT; FAMILY SIZE; FERTILITY; MIDDLE AGED; URINE; YOUNG ADULT;

MICHIGAN; TEXAS; UNITED STATES;

ADOLESCENT; ADULT; BIOLOGICAL MARKERS; DEOXYGUANOSINE; ENVIRONMENT; FAMILY CHARACTERISTICS; FAMILY PLANNING SERVICES; FEMALE; FERTILITY; HUMANS; LONGITUDINAL STUDIES; MALE; MICHIGAN; MIDDLE AGED; OXIDATIVE STRESS; PHTHALIC ACIDS; PREGNANCY; TEXAS; YOUNG ADULT;

EID: 84906256983     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es5024898     Document Type: Article

References (47)

1. Antian, J. Toxicity and health threats of phthalate esters: Review of the literature Environ. Heal. Perspect. 1973, 1-26
2. Guo, Y.; Kannan, K. Comparative assessment of human exposure to phthalate ethers from house dust in China and the United States Environ. Sci. Technol. 2011, 45, 3788-3794
3. Schecter, A.; Lorber, M.; Guo, Y.; Wu, Q.; Yun, S.; Kannan, K.; Miller, J.; Hynan, L. S.; Cheng, D.; Colacino, J.; Birnbaum, L. Phthalate concentrations and dietary exposure from food purchased in New York State Environ. Heal. Perspect. 2013, 121, 473-479
4. Guo, Y.; Kannan, K. A survey of phthalates and parabens in personal care products from the United States and its implications for human exposure Environ. Sci. Technol. 2013, 47, 14442-14449
5. Silva, M. J.; Barr, D. B.; Reidy, J. A.; Malek, N. A.; Hodge, C. C.; Caudill, S. P.; Brock, J. W.; Needham, L. L.; Calafat, A. M. Urinary levels of seven phthalate metabolites in the US population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000 Environ. Heal. Perspect. 2004, 112, 331-338
6. Martino-Andrade, A. J.; Chahoud, I. Reproductive toxicity of phthalate esters Mol. Nutr. Food Res. 2010, 54, 148-157
7. Meeker, J. D. Exposure to environmental endocrine disrupting compounds and men's health Maturitas 2010, 66, 236-241
8. Huang, P. C.; Liou, S. H.; Ho, I. K.; Chiang, H. C.; Huang, H. I.; Wang, S. L. Phthalates exposure and endocrinal effects: An epidemiological review J. Food Drug Anal. 2012, 20, 719-833
9. Zhang, Y. H.; Zheng, L. X.; Chen, B. H. Phthalate exposure and human semen quality in Shanghai: A cross-sectional study Biomed. Environ. Sci. 2006, 19, 205-209
10. Hauser, R.; Meeker, J. D.; Singh, N. P.; Silva, M. J.; Ryan, L.; Duty, S.; Calafat, A. M. DNA damage in human sperm is related to urinary levels of phthalate monoester and oxidative metabolites Hum. Reprod. 2007, 22, 688-695
11. Meeker, J. D.; Calafat, A. M.; Hauser, R. Di(2-ethylhexyl) phthalate metabolites may alter thyroid hormone levels in men Environ. Heal. Perspect. 2007, 115, 1029-1034
12. Schmidt, J.-S.; Schaedlich, K.; Fiandanese, N.; Pocar, P.; Fischer, B. Effective of di(2-ethylhexyl) phthalate (DEHP) on female fertility and adipogenesis in C3H/N mice Environ. Heal. Perspect. 2012, 120, 1123-1129
13. Toft, G.; Jonsson, B. A. G.; Lindh, C. H.; Jensen, T. K.; Hjollund, N. H.; Vested, A.; Bonde, J. P. Association between pregnancy loss and urinary phthalate levels around the time of conception Environ. Health Perspect. 2012, 120, 458-463
14. Zeman, F. A.; Boudet, C.; Tack, K.; Barneaud, A. F.; Brochot, C.; Pery, A. R. R.; Oleko, A.; Vandentorren, S. Exposure assessment of phthalates in French pregnant women: Results of the ELFE pilot study Int. J. Hyg. Envir. Health 2013, 216, 271-279
15. Tranfo, G.; Caporossi, L.; Paci, E.; Aragona, C.; Romanzi, D.; De Carolis, C.; De Rosa, M.; Capanna, S.; Paraleo, B.; Pera, A. Urinary phthalate monoesters concentration in couples with infertility problems Toxicol. Lett. 2012, 213, 15-20
16. Braun, J. M.; Smith, K. W.; Williams, P. L.; Calafat, A. M.; Berry, K.; Ehrlich, S.; Hauser, R. Variability of urinary phthalate metabolites and bisphenol A concentrations before and during pregnancy Environ. Health Perspect. 2012, 120, 739-745
17. Kay, V. R.; Chambers, C.; Foster, W. G. Reproductive abd developmental effects of phthalate diesters in females Crit. Rev. Toxicol. 2013, 43, 200-219
18. Aqarwal, A.; Aponte-Mellado, A.; Premkumar, B. J.; Shaman, A.; Gupta, S. The effects of oxidative stress on female reproduction: A review Reprod. Biol. Endocrinol. 2012, 10, 49
19. Pilger, A.; Rudiger, H. W. 8-hydroxy-2′-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposure Int. Arch. Occup. Environ. Health 2006, 80, 1-15
20. Wu, L. L.; Chiou, C.-C.; Chang, P.-Y.; Wu, J. T. Urinary 8-OHdG: A marker of oxidative stress to DNA and a risk factor for cancer, atherosclerosis and diabetics Clin. Chim. Acta 2004, 339, 1-9
21. Valavanidis, A.; Vlachoqianni, T.; Fiotakis, C. 8-hydroxy-2′- deoxyguanosine (8-OHDG): A critical biomarker of oxidative stress and carcinogenesis J. Environ. Sci. Health, Part C: Environ. Carcin. Ecotoxicol. Rev. 2009, 27, 120-139
22. Wang, Q.; Wang, L.; Chen, X.; Rao, K. M.; Lu, S. Y.; Ma, S. T.; Jiang, P.; Zheng, D.; Xu, S. Q.; Zheng, H. Y.; Wang, J. S.; Yu, Z.-Q.; Zhang, R.; Tao, Y.; Yuan, J. Increased urinary 8-hydroxy-2′-deoxuguanosine levels in workers exposed to di-(2-ethylhexyl)phthalate in a waste plastic recycling site in China Environ. Sci. Pollut. Res. 2011, 18, 987-996
23. Buck Louis, G.; Sundaram, R.; Sweeney, A. M.; Schisterman, E. F.; Maisog, J.; Kannan, K. Urinary bisphenol A, phthalates, and couple fecundity: the Longitudinal investigation of fertility and the environment (LIFE) study Fertil. Steril. 2014, 101, 1359-1366
24. Buck Louis, G. M.; Schisterman, E. F.; Sweeney, A. M.; Wilcosky, T. C.; Gore-Langton, R. E.; Lynch, C. D.; Barr, D. B.; Schrader, S. M.; Kim, S.; Chen, Z.; Sundaram, R. Designing prospective cohort studies for assessing reproductive and developmental toxicity during sensitive windows of human reproduction and development-the LIFE Study Paediatr. Perinat. Epidemiol. 2011, 25, 413-424
25. Matsumoto, Y.; Ogawa, Y.; Yoshida, R.; Shimamori, A.; Kasai, H.; Ohta, H. The stability of the oxidative stress marker, urinary 8-hydroxy-2′- deoxyguanosine (8-OHdG), when stored at room temperature J. Occup. Health 2008, 50, 366-372
26. Guo, Y.; Wang, L.; Kannan, K. Effect of storage time and temperature on levels of phthalate metabolites and bisphenol A in Urine Adv. Environ. Res. 2013, 2, 9-17
27. Guo, Y.; Wu, Q.; Kannan, K. Phthalate metabolites in urine from China, and implications for human exposures Environ. Int. 2011, 37, 893-898
28. Hosozumi, C.; Toriba, A.; Chuesaard, T.; Kameda, T.; Tang, N.; Hayakawa, K. Analysis of 8-hydroxy-2′-deoxyguanosine in human urine using hydrophilic interaction chromatography with tandam mass spectrometry J. Chromatogr. B: Anal. Technol. Biomed. Life Sci. 2012, 893-894, 173-176
29. Department of Health and Human Services; Centers for Disease Control and Prevention. Fourth National Report on Human Exposure to Environmental Chemicals. http://www.cdc.gov/exposurereport/pdf/FourthReport.pdf (accessed Jan 25, 2014).
30. Duty, S. M.; Ackerman, R. M.; Calafat, A. M.; Hauser, R. Personal care product use predicts urinary concentrations of some phthalate monoesters Environ. Health Perspect. 2005, 113, 1530-1535
31. Parlett, L. E.; Calafat, A. M.; Swan, S. H. Women's exposure to phthalates in relation to use of personal care products J. Exposure Sci. Environ. Epidemiol. 2012, 1-10
32. Guo, Y.; Zhang, Z.; Liu, L.; Li, Y.; Ren, N.; Kannan, K. Occurrence and profiles of phthalates in foodstuffs from China and their implications for human exposure J. Agric. Food Chem. 2012, 60, 6913-6919
33. Hatch, E. E.; Nelson, J. W.; Qureshi, M. M.; Weinberg, J.; Moore, L. L.; Singer, M.; Webster, T. F. Association of urinary phthalate metabolite concentrations with body mass index and waist circumference: a cross-sectional study of NHANES data, 1999-2002. Environ. Health 2008, 7,27.
34. Stahlhut, R. W.; van Wijngaarden, E.; Dye, T. D.; Cook, S.; Swan, S. H. Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males Environ. Health Perspect. 2007, 115, 876-882
35. Teitelbaum, S.; Mervish, N.; Moshier, E. L.; Vangeepuram, N.; Galves, M. P.; Calafat, A.; Silva, M. J.; Brenner, B. L.; Wolff, M. S. Association between phthalate metabolite urinary concentrations and body size measures in New York City children Environ. Res. 2012, 112, 186-193
36. Guo, Y.; Alomirah, H.; Cho, H.-S.; Minh, T. B.; Mohd, M. A.; Nakata, H.; Kannan, K. Occurrences of phthalate metabolites in human urine from several Asian countries Environ. Sci. Technol. 2011, 45, 3138-3144
37. Seo, K. W.; Kim, K. B.; Kim, Y. J.; Choi, J. Y.; Lee, K. T.; Choi, K. S. Comparison of oxidative stress and changes of xenobiotic metabolizing enzymes induced by phthalate in rats Food Chem. Toxicol. 2004, 42, 107-114
38. Shono, T.; Taguchi, T. Short-time exposure to mono-n-butyl phthalate (mBP) induced oxidative stress associated with DNA damage and the atrophy of the testis in pubertal rats Environ. Sci. Pollut. Res. 2014, 21, 3187-3190
39. Lord, T.; Aitken, J. R. Oxidative stress and ageing of the post-ovulatory oocyte Reproduction 2013, 146, R217-R227
40. Guz, J.; Gackowskl, D.; Foksinski, M.; Rozalski, R.; Zarakowska, E.; Siomek, A.; Szpila, A.; Kotzbach, M.; Kotzbach, R.; Olinski, R. Comparison of oxidative stress/DNA damage in semen and blood of fertile and infertile men PLoS One 2013, 8, e68490
41. Calafat, A. M.; McKee, R. H. Integrating biomonitoring exposure data into the risk assessment process: Phthalates diethyl phthalate and di(2-ethylhexyl) phthalate as a case study Environ. Health Perspect. 2006, 114, 1783-1789
42. Koch, H. M.; Drexler, H.; Angerer, J. An estimation of the daily intake of di(2-ethylhexyl)phthalate (DEHP) and other phthalates in the general population Int. J. Hyg. Environ. Health 2003, 206, 77-83
43. Jackson, S. Creatinine in urine as an index of urinary excretion rate Health Phys. 1966, 12, 737-850
44. Koch, H. M.; Bolt, H. M.; Angerer, J. Di(2-ethylhexyl)phthalate (DEHP) metabolites in human urine and serum after a single oral dose of deuterium-labelled DEHP Arch. Toxicol. 2004, 78, 123-130
45. Marsee, K.; Woodruff, T. J.; Axelrad, D. A.; Calafat, A. M.; Swan, S. H. Estimated daily phthalate exposures in a population of mothers of male infants exhibiting reduced anogenital distance Environ. Health Perspect. 2006, 114, 805-809
46. Aylward, L. L.; Hays, S. M.; Gagne, M.; Krishnan, K. Derivation of Biomonitoring Equivalents for di-n-butyl phthalate (DBP), benzylbutyl phthalate (BzBP), and diethyl phthalate (DEP) Regul. Toxicol. Pharmacol. 2009, 55, 259-267
47. Wormuth, M.; Scheringer, M.; Vollenweider, M.; Hungerbuhler, K. What are the sources of exposure to eight frequently used phthalic acid esters in Europeans? Risk Anal. 2006, 26, 803-824