Phthalate concentrations and dietary exposure from food purchased in New York state

Environmental Health Perspectives

Volumn 121, Issue 4, 2013, Pages 473-479

  Schecter, Arnold ^a   Lorber, Matthew ^b   Guo, Ying ^c   Wu, Qian ^c,d   Yun, Se Hun ^c,d   Kannan, Kurunthachalam ^c,d   Hommel, Madeline ^a   Imran, Nadia ^a   Hynan, Linda S ^e   Cheng, Dunlei ^a   Colacino, Justin A ^f   Birnbaum, Linda S ^g,h  

^a UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c WADSWORTH CENTER   (United States)

^d STATE UNIVERSITY OF NEW YORK   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f UNIVERSITY OF MICHIGAN   (United States)

^g NATIONAL INSTITUTES OF HEALTH   (United States)

^h NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

BBZP; DEHP; DEP; DiBP; Market basket survey; Phthalate exposure

Indexed keywords

PHTHALIC ACID; PHTHALIC ACID BENZYL BUTYL ESTER; PHTHALIC ACID BIS (2 ETHYLHEXYL) ESTER; PHTHALIC ACID DIMETHYL ESTER; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; DIETARY INTAKE; ENVIRONMENTAL EXPOSURE; FOOD; FOOD INTAKE; HUMAN; MASS FRAGMENTOGRAPHY; PRIORITY JOURNAL;

ADULT; CHILD; DIET; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; FOOD CONTAMINATION; HUMANS; NEW YORK; PHTHALIC ACIDS;

EID: 84875892730     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1206367     Document Type: Article

References (35)

1. Agency for Toxic Substances and Disease Registry. 2002. Toxicological Profile for Di-(2-ethylhexyl) Phthalate (DEHP). Atlanta, GA:Agency for Toxic Substances and Disease Registry.
2. Bodner-Montville J, Ahuja JKC, Ingwersen LA, Haggerty ES, Enns CE, Perlo BP. 2006. USDA Food and Nutrient Database for Dietary Studies: released on the web. J Food Comp Anal 19(suppl 1):S100-S107.
3. Cao, Xu-Liang. 2010. Phthalate esters in foods: sources, occurrence, and analytical methods. Comp Rev Food Sci Food Safety 9:21-43.
4. Clark K, David RM, Guinn R, Kramarz KW, Lampi M, Staples CA. 2011. Modeling human exposure to phthalate esters: a comparison of indirect and biomonitoring estimation methods. Hum Ecol Risk Assess 17(4):923-965.
5. Colón I, Caro D, Bourdony CJ, Rosario O. 2000. Identification of phthalate esters in the serum of young Puerto Rican girls with premature breast development. Environ Health Perspect 108:895-900.
6. CPSC (Consumer Product Safety Commission). 2010. Chronic Hazard Advisory Panel (CHAP) on Phthalates. Available: http://www.cpsc.gov/about/cpsia/chapmain.html [accessed 22 May 2012].
7. Dinovi M, Brookmire L. 2011. Memorandum from M Dinovi and L Brookmire, Food and Drug Administration, to M Lorber, U.S. Environmental Protection Agency. Average Adult Intake for a Specific Class of Condiments, 17 October 2011
8. Duty SM, Singh NP, Silva MJ, Barr DB, Brock JW, Ryan L, et al. 2003. The relationship between environmental exposures to phthalates and DNA damage in human sperm using the neutral comet assay. Environ Health Perspect 111:1164-1169
9. Fierens T, Servaes K, Van Holderbeke M, Geerts L, De Henauw S, Sioen I, et al. 2012. Phthalates in food-Part 1: Analysis in food products and packaging materials sold on the Belgian market. Food Chem Toxicol 50(7):2575-2583.
10. Foster PMD, Cattley RC, Mylchreest E. 2000. Effects of di-n-butyl phthalate (DBP) on male reproductive development in the rat: implications for human risk assessment. Food Chem Toxicol 38(suppl 1):S97-S99.
11. Fromme H, Gruber L, Schlummer M, Wolz G, Böhmer S, Angerer J, et al. 2007. Intake of phthalates and di(2-ethylhexyl)adipate: results of the integrated exposure assessment survey based on duplicate diet samples and biomonitoring data. Environ Int 33(8):1012-1020.
12. FSA (Food Standards Agency). 2012. Determination of Phthalates in Foods and Establishing Methodology to Distinguish their Source. Available: http://www.food.gov.uk/science/ research/contaminantsresearch/env-cont/organic-cont/c01048/#.US5Q-egS30Q [accessed 7 March 2013].
13. Green R, Hauser R, Calafat AM, Weuve J, Schettler T, Ringer S, et al. 2005. Use of di(2-ethylhexyl) phthalate-containing medical products and urinary levels of mono(2-ethylhexyl) phthalate in neonatal intensive care unit infants. Environ Health Perspect 113:1222-1225.
14. Guo Y, Kannan K. 2012. Challenges encountered in the analysis of phthalate esters in foodstuffs and other biological matrices. Anal Bioanal Chem 404(9):2539-2554.
15. Guo Y, Zhang Z, Liu L, Li Y-F, Ren N, Kannan K. 2012. Occurrence and profiles of phthalates in foodstuffs from China, and their implications for human exposures. J Agric Food Chem 60: 6913-6919.
16. Kamrin MA. 2009. Phthalate risks, phthalate regulation, and public health: a review. J Toxicol Environ Health B Crit Rev 12(2):157-174.
17. Koch HM, Calafat AM. 2009. Human body burdens of chemicals used in plastic manufacture. Philos Trans R Soc Lond B Biol Sci 364:2063-2078.
18. Latini G, de Felice C, Presta G, Del Vecchio A, Paris I, Ruggieri F, et al. 2003. In utero exposure to di-(2-ethylhexyl) phthalate and duration of human pregnancy. Environ Health Perspect 111:1783-1785.
19. National Academies of Science. 2008. Phthalates and Cumulative Risk Assessment-The Task Ahead. Available: http://www.nap.edu/openbook.php?record_id=12528 [accessed 13 September 2012].
20. Page BD, Lacroix GM. 1995. The occurrence of phthalate ester and di-2-ethylhexyl adipate plasticizers in Canadian packaging and food sampled in 1985-1989: a survey. Food Addit Contam 12:129-151.
21. Petersen JH, Breindahl T. 2000. Placticizers in total diet samples, baby food and infant formulae. Food Addit Contam 17(2):133-141.
22. Schecter A, Colacino J, Haffner D, Patel K, Opel M, Päpke O, et al. 2010. Perfluorinated compounds, polychlorinated biphenyls, and organ ochlorine pesticide contamination in composite food samples from Dallas, Texas, USA. Environ Health Perspect 118:796-802.
23. Schecter A, Päpke O, Harris TR, Tung KC, Musumba A, Olson J, et al. 2006. Polybrominated diphenyl ether (PBDE) levels in an expanded market basket survey of U.S. food and estimated PBDE dietary intake by age and sex. Environ Health Perspect 114:1515-1520.
24. Schecter A, Szabo DT, Miller J, Gent TL, Malik-Bass N, Petersen M, et al. 2012. Hexabrom ocyclododecane (HBCD) stereoisomers in U.S. food from Dallas, Texas. Environ Health Perspect 120:1260-1264.
25. Swan SH, Main KM, Liu F, Stewart SL, Kruse RL, Calafat AM, et al. 2005. Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environ Health Perspect 113:1056-1061.
26. Tsumura Y, Ishimitsu S, Saito I, Sakai H, Kobayashi Y, Tonogai Y. 2001. Eleven phthalate esters and di(2-ethylhexyl) adipate in one-week duplicate diet samples obtained from hospitals and their estimated daily intake. Food Addit Contam 18(5):449-460.
27. U.S. EPA (U.S. Environmental Protection Agency). 2008. ChildSpecific Exposure Factors Handbook (Final Report). EPA/600/R-06/096F. Washington, DC:U.S. EPA. Available: http://ofmpub.epa.gov/eims/eimscomm.getfile?p_download_id=484738 [accessed 7 March 2013].
28. U.S. EPA (U.S. Environmental Protection Agency). 2011a. Existing Chemicals. Available: http://www.epa.gov/oppt/existingchemicals/ [accessed 7 March 2012].
29. U.S. EPA (U.S. Environmental Protection Agency). 2011b. Exposure Factors Handbook: 2011 Edition. EPA/600/R-09/052F. Washington, DC:U.S. EPA, National Center for Enviromental Assessment. Available: http://www.epa.gov/ncea/efh/pdfs/efh-complete.pdf [accessed 7 March 2013]
30. U.S. EPA (U.S. Environmental Protection Agency). 2011c Phthalates Action Plan Summary. Available: http://www.epa.gov/oppt/existingchemicals/pubs/actionplans/phthalates.html [accessed 12 March 2012]
31. U.S. EPA (U.S. Environmental Protection Agency). 2012a. Butyl Benzyl Phthalate (CASRN 85-68-7). Available: http://www.epa.gov/iris/subst/0293.htm [accessed 26 November 2012].
32. U.S. EPA (U.S. Environmental Protection Agency). 2012b. Dibutyl Phthalate (CASRN 84-74-2). Available: http://www.epa.gov/iris/subst/0038.htm [accessed 15 March 2012].
33. U.S. EPA (U.S. Environmental Protection Agency). 2012c. Di(2-ethylhexyl)phthalate (DEHP) (CASRN 117-81-7). Available: http://www.epa.gov/iris/subst/0014.htm [accessed 15 March 2012].
34. U.S. EPA (U.S. Environmental Protection Agency). 2012d. Diethyl Phthalate (CASRN 84-66-2). Available: http://www.epa.gov/iris/subst/0226.htm [accessed 15 March 2012]
35. Wormuth M, Scheringer M, Vollenweider M, Hungerbühler K. 2006. What are the sources of exposure to eight frequently used phthalic acid esters in Europeans? Risk Anal 26(3):803-824.