Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA

Oncotarget

Volumn 5, Issue 14, 2014, Pages 5581-5590

  Ohno, Motoko ^a   Otsuka, Motoyuki ^a,b   Kishikawa, Takahiro ^a   Shibata, Chikako ^a   Yoshikawa, Takeshi ^a   Takata, Akemi ^a   Muroyama, Ryosuke ^c   Kowatari, Norie ^c   Sato, Masaya ^a   Kato, Naoya ^c   Kuroda, Shun'ichi ^d   Koike, Kazuhiko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d NAGOYA UNIVERSITY   (Japan)

Author keywords

Bionanocapsules; Drug delivery; Hepatitis; Primary hepatocyte

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VIRUS L PROTEIN; MESSENGER RNA; MICRORNA; MICRORNA 93; PROTEIN; PROTEIN MHC CLASS I POLYPEPTIDE RELATED SEQUENCE A; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; HLA ANTIGEN CLASS 1; MHC CLASS I-RELATED CHAIN A; MIRN93 MICRORNA, HUMAN;

ARTICLE; BIONANOCAPSULE; CANCER INHIBITION; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE THERAPY; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; LIVER CELL CARCINOMA; MICA GENE; PROTEIN EXPRESSION; RNA TRANSCRIPTION; UPREGULATION; VIRAL CLEARANCE; VIRUS REPLICATION; ANIMAL; BIOSYNTHESIS; BLOOD; CHIMERA; GENETICS; LIVER TUMOR; METABOLISM; MOUSE; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE; VIROLOGY;

ANIMALS; CELL LINE, TUMOR; CHIMERA; DOWN-REGULATION; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HEPATOCYTES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; LIVER NEOPLASMS; MICE; MICRORNAS; VIRUS REPLICATION;

EID: 84906230495     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2143     Document Type: Article

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