Coordinated regulation of transcription and alternative splicing by the thyroid hormone receptor and its associating coregulators

Biochemical and Biophysical Research Communications

Volumn 451, Issue 1, 2014, Pages 24-29

  Satoh, Tetsurou ^a   Katano Toki, Akiko ^a   Tomaru, Takuya ^a   Yoshino, Satoshi ^a   Ishizuka, Takahiro ^a   Horiguchi, Kazuhiko ^a   Nakajima, Yasuyo ^a   Ishii, Sumiyasu ^a   Ozawa, Atsushi ^a   Shibusawa, Nobuyuki ^a   Hashimoto, Koshi ^a   Mori, Masatomo ^b   Yamada, Masanobu ^a  

^a GUNMA UNIVERSITY   (Japan)

^b Kitakanto Molecular Novel Research Institute for Obesity and Metabolism   (Japan)

Author keywords

150 kDa; Alternative splicing; Polypyrimidine tract binding protein associated splicing factor; Thyroid hormone receptor; Thyroid hormone receptor associated protein; Transcription

Indexed keywords

HERMES ANTIGEN; LIOTHYRONINE; MEDIATOR COMPLEX; MESSENGER RNA PRECURSOR; POLYPYRIMIDINE TRACT BINDING PROTEIN; THYROID HORMONE RECEPTOR; CD44 PROTEIN, HUMAN; DNA BINDING PROTEIN; LUCIFERASE; PTB-ASSOCIATED SPLICING FACTOR; RNA BINDING PROTEIN; THRAP3 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

AGAR GEL ELECTROPHORESIS; ALTERNATIVE RNA SPLICING; ARTICLE; CYTOMEGALOVIRUS; DNA RESPONSIVE ELEMENT; EXON; EXPRESSION VECTOR; FEMALE; GENE ACTIVATION; GENETIC TRANSCRIPTION; HELA CELL LINE; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; DRUG EFFECTS; GENETICS; METABOLISM;

CYTOMEGALOVIRUS;

ALTERNATIVE SPLICING; ANTIGENS, CD44; DNA-BINDING PROTEINS; EXONS; HELA CELLS; HUMANS; LUCIFERASES; PROMOTER REGIONS, GENETIC; RECEPTORS, THYROID HORMONE; RESPONSE ELEMENTS; RNA-BINDING PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRIIODOTHYRONINE;

EID: 84906225733     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.07.029     Document Type: Article

References (41)

1. K.M. Neugebauer On the importance of being co-transcriptional J. Cell Sci. 115 2002 3865 3871
2. S. Shukla, and S. Oberdoerffer Co-transcriptional regulation of alternative pre-mRNA splicing Biochem. Biophys. Acta 2012 1819 673 683
3. E.T. Wang, R. Sandberg, and S. Luo et al. Alternative isoform regulation in human tissue transcriptomes Nature 456 2008 470 476
4. J. Tazi, N. Bakkour, and S. Stamm Alternative splicing and disease Biochim. Biophys. Acta 1792 2009 14 26
5. A. Piekiełko-Witkowska, and A. Nauman Alternative splicing and its role in pathologies of the endocrine system Endokrynol. Pol. 62 2011 160 170
6. J. Boultwood, H. Dolatshad, and S.S. Varanasi et al. The role of splicing factor mutations in the pathogenesis of the myelodysplastic syndromes Adv. Biol. Regul. 54 2014 153 161
7. C.K. Glass Differential recognition of target genes by nuclear receptor monomers dimers, and heterodimers Endocr. Rev. 15 1994 391 407
8. R.C. Ribeiro, P.J. Kushner, and J.D. Baxter The nuclear hormone receptor gene superfamily Annu. Rev. Med. 46 1995 443 453
9. C.K. Glass, and M.G. Rosenfeld The coregulator exchange in transcriptional functions of nuclear receptors Genes Dev. 14 2000 121 141
10. D.M. Lonard, R.B. Lanz, and B.W. O'Malley Nuclear receptor coregulators and human disease Endocr. Rev. 28 2007 575 587
11. D.M. Lonard, and B.W. O'Malley Nuclear receptor coregulators: modulators of pathology and therapeutic targets Nat. Rev. Endocrinol. 8 2012 598 604
12. M. Monsalve, Z. Wu, and G. Adelmant et al. Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1 Mol. Cell 6 2000 307 316
13. D. Auboeuf, A. Hönig, and S.M. Berget et al. Coordinate regulation of transcription and splicing by steroid receptor coregulators Science 298 2002 416 419
14. 65-related proteins CAPERα and CAPERβ Mol. Cell 17 2005 429 439
15. J. Sun, A.L. Blair, and S.E. Aiyar et al. Cofactor of BRCA1 modulates androgen-dependent transcription and alternative splicing J. Steroid Biochem. Mol. Biol. 107 2007 131 139
16. P. Rajan, L. Gaughan, and C. Dalgliesh et al. The RNA-binding and adaptor protein Sam68 modulates signal-dependent splicing and transcriptional activity of the androgen receptor J. Pathol. 215 2008 67 77
17. M.A. Lazar Thyroid hormone action: a binding contract J. Clin. Invest. 112 2003 497 499
18. M.J. Latasa, B. Belandia, and A. Pascual Thyroid hormones regulate beta-amyloid gene splicing and protein secretion in neuroblastoma cells Endocrinology 139 1998 2692 2698
19. D.C. Timmer, O. Bakker, and W.M. Wiersinga Triiodothyronine affects the alternative splicing of thyroid hormone receptor alpha mRNA J. Endocrinol. 179 2003 217 225
20. J.D. Fondell, H. Ge, and R.G. Roeder Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex Proc. Natl. Acad. Sci. U.S.A. 93 1996 8329 8333
21. K.M. Lee, W. Hsu Ia, and W.Y. Tarn TRAP150 activates pre-mRNA splicing and promotes nuclear mRNA degradation Nucleic Acids Res. 38 2010 3340 3350
22. F. Heyd, and K.W. Lynch Phosphorylation-dependent regulation of PSF by GSK3 controls CD45 alternative splicing Mol. Cell 40 2010 126 137
23. K. Horiuchi, T. Kawamura, and H. Iwanari et al. Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle J. Biol. Chem. 288 2013 33292 33302
24. J.G. Patton, E.B. Porro, and J. Galceran et al. Cloning and characterization of PSF, a novel pre-mRNA splicing factor Genes Dev. 7 1993 393 406
25. P. Close, P. East, and A.B. Dirac-Svejstrup et al. DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation Nature 484 2012 386 389
26. M. Mathur, P.W. Tucker, and H.H. Samuels PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors Mol. Cell. Biol. 21 2001 2298 2311
27. X. Dong, O. Shylnova, and J.R. Challis et al. Identification and characterization of the protein-associated splicing factor as a negative co-regulator of the progesterone receptor J. Biol. Chem. 280 2005 13329 13340
28. X. Dong, J. Sweet, and J.R. Challis et al. Transcriptional activity of androgen receptor is modulated by two RNA splicing factors, PSF and p54nrb Mol. Cell. Biol. 27 2007 4863 4875
29. A. Katano-Toki, T. Satoh, and T. Tomaru et al. THRAP3 interacts with HELZ2 and plays a novel role in adipocyte differentiation Mol. Endocrinol. 27 2013 769 780
30. T. Tomaru, T. Satoh, and S. Yoshino et al. Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma Endocrinology 147 2006 377 388
31. K.K. Kim, Y.C. Kim, R.S. Adelstein, and S. Kawamoto Fox-3 and PSF interact to activate neural cell-specific alternative splicing Nucleic Acids Res. 39 2011 3064 3078
32. T. Satoh, T. Ishizuka, and S. Yoshino et al. Roles of proteasomal 19S regulatory particles in promoter loading of thyroid hormone receptor Biochem. Biophys. Res. Commun. 386 2009 697 702
33. E. Stickeler, S.D. Frase, and A. Honig et al. The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4 EMBO J. 20 2001 3821 3830
34. A. Emili, M. Shale, and S. McCracken et al. Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD RNA 8 2002 1102 1111
35. C. Merz, H. Urlaub, and C.L. Will et al. Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment RNA 13 2007 116 128
36. K.T. Lin, R.M. Lu, and W.Y. Tarn The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo Mol. Cell. Biol. 24 2004 9176 9185
37. A.C. Goldstrohm, T.R. Albrecht, and C. Suñé et al. The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1 Mol. Cell. Biol. 21 2001 7617 7628
38. Y. Huang, W. Li, and X. Yao et al. Mediator complex regulates alternative mRNA processing via the MED23 subunit Mol. Cell 45 2012 459 469
39. O. Gozani, J.G. Patton, and R. Reed A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction EMBO J. 13 1994 3356 3367
40. C.S. Lutz, C. Cooke, and J.P. O'Connor et al. The snRNP-free U1A (SF-A) complex(es): identification of the largest subunit as PSF, the polypyrimidine-tract binding protein-associated splicing factor RNA 4 1998 1493 1499
41. E. Rosonina, J.Y. Ip, and J.A. Calarco et al. Role for PSF in mediating transcriptional activator-dependent stimulation of pre-mRNA processing in vivo Mol. Cell. Biol. 25 2005 6734 6746