메뉴 건너뛰기




Volumn 67, Issue 1, 2014, Pages 7-14

Exposure to entry inhibitors alters hiv infectiousness and sensitivity to broadly neutralizing monoclonal antibodies

Author keywords

antibodies; antiretrovirals; entry inhibitors; HIV; maraviroc; T 20

Indexed keywords

CHEMOKINE RECEPTOR CCR5; ENFUVIRTIDE; GLYCOPROTEIN GP 120; HUMAN IMMUNODEFICIENCY VIRUS FUSION INHIBITOR; MARAVIROC; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2F5; MONOCLONAL ANTIBODY 2G12; MONOCLONAL ANTIBODY 4E10; MONOCLONAL ANTIBODY B12; MONOCLONAL ANTIBODY PG9; MONOCLONAL ANTIBODY VRC01; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; CYCLOHEXANE DERIVATIVE; TRIAZOLE DERIVATIVE;

EID: 84906084699     PISSN: 15254135     EISSN: 10779450     Source Type: Journal    
DOI: 10.1097/QAI.0000000000000223     Document Type: Article
Times cited : (3)

References (49)
  • 1
    • 0142187273 scopus 로고    scopus 로고
    • Enfuvirtide (T-20): A novel human immunodeficiency virus type 1 fusion inhibitor
    • Cervia JS, Smith MA. Enfuvirtide (T-20): a novel human immunodeficiency virus type 1 fusion inhibitor. Clin Infect Dis. 2003;37:1102-1106.
    • (2003) Clin Infect Dis. , vol.37 , pp. 1102-1106
    • Cervia, J.S.1    Smith, M.A.2
  • 2
    • 78751679808 scopus 로고    scopus 로고
    • Antiviral activity, pharmaco-kinetics, and safety of BMS-488043, a novel oral small-molecule HIV-1 attachment inhibitor, in HIV-1-infected subjects
    • Hanna GJ, Lalezari J, Hellinger JA, et al. Antiviral activity, pharmaco-kinetics, and safety of BMS-488043, a novel oral small-molecule HIV-1 attachment inhibitor, in HIV-1-infected subjects. Antimicrob Agents Che-mother. 2011;55:722-728.
    • (2011) Antimicrob Agents Che-mother. , vol.55 , pp. 722-728
    • Hanna, G.J.1    Lalezari, J.2    Hellinger, J.A.3
  • 3
    • 84866124136 scopus 로고    scopus 로고
    • Pharmacodynamics, safety, and pharmacokinetics of BMS-663068, an oral HIV-1 attachment inhibitor in HIV-1-infected subjects
    • Nettles RE, Schurmann D, Zhu L, et al. Pharmacodynamics, safety, and pharmacokinetics of BMS-663068, an oral HIV-1 attachment inhibitor in HIV-1-infected subjects. J Infect Dis. 2012;206:1002-1011.
    • (2012) J Infect Dis. , vol.206 , pp. 1002-1011
    • Nettles, R.E.1    Schurmann, D.2    Zhu, L.3
  • 4
    • 27644510382 scopus 로고    scopus 로고
    • Maraviroc (UK-427, 857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity
    • Dorr P, Westby M, Dobbs S, et al. Maraviroc (UK-427, 857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity. Antimicrob Agents Chemother. 2005;49:4721-4732.
    • (2005) Antimicrob Agents Chemother. , vol.49 , pp. 4721-4732
    • Dorr, P.1    Westby, M.2    Dobbs, S.3
  • 5
    • 0031891516 scopus 로고    scopus 로고
    • AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor
    • Donzella GA, Schols D, Lin SW, et al. AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor. Nat Med. 1998;4: 72-77.
    • (1998) Nat Med. , vol.4 , pp. 72-77
    • Donzella, G.A.1    Schols, D.2    Lin, S.W.3
  • 6
    • 84871904965 scopus 로고    scopus 로고
    • Escape from human immunodeficiency virus type 1 (HIV-1) entry inhibitors
    • De Feo CJ, Weiss CD. Escape from human immunodeficiency virus type 1 (HIV-1) entry inhibitors. Viruses. 2012;4:3859-3911.
    • (2012) Viruses. , vol.4 , pp. 3859-3911
    • De Feo, C.J.1    Weiss, C.D.2
  • 7
    • 84860342068 scopus 로고    scopus 로고
    • Mini CD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency
    • Grupping K, Selhorst P, Michiels J, et al. Mini CD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency. Retrovirology. 2012;9:36.
    • (2012) Retrovirology. , vol.9 , pp. 36
    • Grupping, K.1    Selhorst, P.2    Michiels, J.3
  • 8
    • 84863116880 scopus 로고    scopus 로고
    • HIV-1 clinical isolates resistant to CCR5 antagonists exhibit delayed entry kinetics that are corrected in the presence of drug
    • Putcharoen O, Lee SH, Henrich TJ, et al. HIV-1 clinical isolates resistant to CCR5 antagonists exhibit delayed entry kinetics that are corrected in the presence of drug. J Virol. 2012;86:1119-1128.
    • (2012) J Virol. , vol.86 , pp. 1119-1128
    • Putcharoen, O.1    Lee, S.H.2    Henrich, T.J.3
  • 9
    • 84864018506 scopus 로고    scopus 로고
    • Vicriviroc resistance decay and relative replicative fitness in HIV-1 clinical isolates under sequential drug selection pressures
    • Tsibris AM, Hu Z, Paredes R, et al. Vicriviroc resistance decay and relative replicative fitness in HIV-1 clinical isolates under sequential drug selection pressures. J Virol. 2012;86:6416-6426.
    • (2012) J Virol. , vol.86 , pp. 6416-6426
    • Tsibris, A.M.1    Hu, Z.2    Paredes, R.3
  • 10
    • 79955398621 scopus 로고    scopus 로고
    • HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropism
    • Roche M, Jakobsen MR, Sterjovski J, et al. HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropism. J Virol. 2011;85:4330-4342.
    • (2011) J Virol. , vol.85 , pp. 4330-4342
    • Roche, M.1    Jakobsen, M.R.2    Sterjovski, J.3
  • 11
    • 77953305009 scopus 로고    scopus 로고
    • HIV-1 resistance to CCR5 antagonists associated with highly efficient use of CCR5 and altered tropism on primary CD4+ T cells
    • Pfaff JM, Wilen CB, Harrison JE, et al. HIV-1 resistance to CCR5 antagonists associated with highly efficient use of CCR5 and altered tropism on primary CD4+ T cells. J Virol. 2010;84:6505-6514.
    • (2010) J Virol. , vol.84 , pp. 6505-6514
    • Pfaff, J.M.1    Wilen, C.B.2    Harrison, J.E.3
  • 12
    • 38949206356 scopus 로고    scopus 로고
    • Passive immunization as tool to identify protective HIV-1 Env epitopes
    • Kramer VG, Siddappa NB, Ruprecht RM. Passive immunization as tool to identify protective HIV-1 Env epitopes. Curr HIV Res. 2007;5:642-655.
    • (2007) Curr HIV Res. , vol.5 , pp. 642-655
    • Kramer, V.G.1    Siddappa, N.B.2    Ruprecht, R.M.3
  • 14
    • 84885401068 scopus 로고    scopus 로고
    • The potential of the human immune system to develop broadly neutralizing HIV-1 antibodies: Implications for vaccine development
    • Zhang Y, Yuan T, Li J, et al. The potential of the human immune system to develop broadly neutralizing HIV-1 antibodies: implications for vaccine development. AIDS. 2013;27:2529-2539.
    • (2013) AIDS. , vol.27 , pp. 2529-2539
    • Zhang, Y.1    Yuan, T.2    Li, J.3
  • 15
    • 0037389643 scopus 로고    scopus 로고
    • Rapid evolution of the neutralizing antibody response to HIV type 1 infection
    • Richman DD, Wrin T, Little SJ, et al. Rapid evolution of the neutralizing antibody response to HIV type 1 infection. Proc Natl Acad Sci USA. 2003;100:4144-4149.
    • (2003) Proc Natl Acad Sci USA. , vol.100 , pp. 4144-4149
    • Richman, D.D.1    Wrin, T.2    Little, S.J.3
  • 16
    • 80053025493 scopus 로고    scopus 로고
    • An allosteric model of maravir-oc binding to CCR5
    • Garcia-Perez J, Rueda P, Alcami J, et al. An allosteric model of maravir-oc binding to CCR5. J Biol Chem. 2011;286:33409-33421.
    • (2011) J Biol Chem. , vol.286 , pp. 33409-33421
    • Garcia-Perez, J.1    Rueda, P.2    Alcami, J.3
  • 17
    • 84884673669 scopus 로고    scopus 로고
    • Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc Complex
    • Tan Q, Zhu Y, Li J, et al. Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc Complex. Science. 2013;341:1387-1390.
    • (2013) Science. , vol.341 , pp. 1387-1390
    • Tan, Q.1    Zhu, Y.2    Li, J.3
  • 18
    • 84864385246 scopus 로고    scopus 로고
    • Maraviroc and other HIV-1 entry inhibitors exhibit a class-specific redistribution effect that results in increased extracellular viral load
    • Kramer VG, Schader SM, Oliveira M, et al. Maraviroc and other HIV-1 entry inhibitors exhibit a class-specific redistribution effect that results in increased extracellular viral load. Antimicrob Agents Chemother. 2012; 56:4154-4160.
    • (2012) Antimicrob Agents Chemother. , vol.56 , pp. 4154-4160
    • Kramer, V.G.1    Schader, S.M.2    Oliveira, M.3
  • 19
    • 0027692502 scopus 로고
    • A synthetic peptide from HIV-1 gp41 is a potent inhibitor of virus-mediated cell-cell fusion
    • Wild C, Greenwell T, Matthews T. A synthetic peptide from HIV-1 gp41 is a potent inhibitor of virus-mediated cell-cell fusion. AIDS Res Hum Retroviruses. 1993;9:1051-1053.
    • (1993) AIDS Res Hum Retroviruses. , vol.9 , pp. 1051-1053
    • Wild, C.1    Greenwell, T.2    Matthews, T.3
  • 20
    • 84887626950 scopus 로고    scopus 로고
    • Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys
    • Barouch DH, Whitney JB, Moldt B, et al. Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys. Nature. 2013;503:224-228.
    • (2013) Nature. , vol.503 , pp. 224-228
    • Barouch, D.H.1    Whitney, J.B.2    Moldt, B.3
  • 21
    • 84887627657 scopus 로고    scopus 로고
    • Antibody-mediated immuno-Therapy of macaques chronically infected with SHIV suppresses virae-mia
    • Shingai M, Nishimura Y, Klein F, et al. Antibody-mediated immuno-Therapy of macaques chronically infected with SHIV suppresses virae-mia. Nature. 2013;503:277-280.
    • (2013) Nature. , vol.503 , pp. 277-280
    • Shingai, M.1    Nishimura, Y.2    Klein, F.3
  • 22
    • 67249131966 scopus 로고    scopus 로고
    • Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers
    • Hessell AJ, Rakasz EG, Poignard P, et al. Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titers. PLoS Pathog. 2009;5: e1000433.
    • (2009) PLoS Pathog. , vol.5
    • Hessell, A.J.1    Rakasz, E.G.2    Poignard, P.3
  • 23
    • 84870562234 scopus 로고    scopus 로고
    • HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
    • Klein F, Halper-Stromberg A, Horwitz JA, et al. HIV therapy by a combination of broadly neutralizing antibodies in humanized mice. Nature. 2012;492:118-122.
    • (2012) Nature. , vol.492 , pp. 118-122
    • Klein, F.1    Halper-Stromberg, A.2    Horwitz, J.A.3
  • 24
    • 0037436188 scopus 로고    scopus 로고
    • Post-exposure prophylaxis with human monoclonal antibodies prevented SHIV89.6P infection or disease in neonatal macaques
    • Ferrantelli F, Hofmann-Lehmann R, Rasmussen RA, et al. Post-exposure prophylaxis with human monoclonal antibodies prevented SHIV89.6P infection or disease in neonatal macaques. AIDS. 2003;17:301-309.
    • (2003) AIDS. , vol.17 , pp. 301-309
    • Ferrantelli, F.1    Hofmann-Lehmann, R.2    Rasmussen, R.A.3
  • 25
    • 84885338257 scopus 로고    scopus 로고
    • HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice
    • Horwitz JA, Halper-Stromberg A, Mouquet H, et al. HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice. Proc Natl Acad Sci USA. 2013;110:16538-16543.
    • (2013) Proc Natl Acad Sci USA. , vol.110 , pp. 16538-16543
    • Horwitz, J.A.1    Halper-Stromberg, A.2    Mouquet, H.3
  • 26
    • 20944446452 scopus 로고    scopus 로고
    • Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
    • Trkola A, Kuster H, Rusert P, et al. Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies. Nat Med. 2005;11:615-622.
    • (2005) Nat Med. , vol.11 , pp. 615-622
    • Trkola, A.1    Kuster, H.2    Rusert, P.3
  • 27
    • 84879290459 scopus 로고    scopus 로고
    • A global approach to HIV-1 vaccine development
    • Stephenson KE, Barouch DH. A global approach to HIV-1 vaccine development. Immunol Rev. 2013;254:295-304.
    • (2013) Immunol Rev. , vol.254 , pp. 295-304
    • Stephenson, K.E.1    Barouch, D.H.2
  • 28
    • 0032947286 scopus 로고    scopus 로고
    • Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies
    • Mascola JR, Lewis MG, Stiegler G, et al. Protection of Macaques against pathogenic simian/human immunodeficiency virus 89.6PD by passive transfer of neutralizing antibodies. J Virol. 1999;73:4009-4018.
    • (1999) J Virol. , vol.73 , pp. 4009-4018
    • Mascola, J.R.1    Lewis, M.G.2    Stiegler, G.3
  • 29
    • 0033951746 scopus 로고    scopus 로고
    • Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies
    • Mascola JR, Stiegler G, VanCott TC, et al. Protection of macaques against vaginal transmission of a pathogenic HIV-1/SIV chimeric virus by passive infusion of neutralizing antibodies. Nat Med. 2000;6:207-210.
    • (2000) Nat Med. , vol.6 , pp. 207-210
    • Mascola, J.R.1    Stiegler, G.2    Vancott, T.C.3
  • 30
    • 0033952103 scopus 로고    scopus 로고
    • Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection
    • Baba TW, Liska V, Hofmann-Lehmann R, et al. Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection. Nat Med. 2000;6:200-206.
    • (2000) Nat Med. , vol.6 , pp. 200-206
    • Baba, T.W.1    Liska, V.2    Hofmann-Lehmann, R.3
  • 31
    • 77951882041 scopus 로고    scopus 로고
    • Toward an antibody-based HIV-1 vaccine
    • Hoxie JA. Toward an antibody-based HIV-1 vaccine. Annu Rev Med. 2010;61:135-152.
    • (2010) Annu Rev Med. , vol.61 , pp. 135-152
    • Hoxie, J.A.1
  • 32
    • 0029063578 scopus 로고
    • Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): Failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1
    • Lusso P, Cocchi F, Balotta C, et al. Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1. J Virol. 1995;69:3712-3720.
    • (1995) J Virol. , vol.69 , pp. 3712-3720
    • Lusso, P.1    Cocchi, F.2    Balotta, C.3
  • 33
    • 0031954686 scopus 로고    scopus 로고
    • Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1
    • Platt EJ, Wehrly K, Kuhmann SE, et al. Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1. J Virol. 1998;72:2855-2864.
    • (1998) J Virol. , vol.72 , pp. 2855-2864
    • Platt, E.J.1    Wehrly, K.2    Kuhmann, S.E.3
  • 34
    • 0025783669 scopus 로고
    • Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1
    • Hwang SS, Boyle TJ, Lyerly HK, et al. Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1. Science. 1991; 253:71-74.
    • (1991) Science. , vol.253 , pp. 71-74
    • Hwang, S.S.1    Boyle, T.J.2    Lyerly, H.K.3
  • 35
    • 0029062117 scopus 로고
    • Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection
    • Freed EO, Englund G, Martin MA. Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection. J Virol. 1995;69:3949-3954.
    • (1995) J Virol. , vol.69 , pp. 3949-3954
    • Freed, E.O.1    Englund, G.2    Martin, M.A.3
  • 36
    • 1142309492 scopus 로고    scopus 로고
    • Evaluation of plasmid DNA removal from lentiviral vectors by benzonase treatment
    • Sastry L, Xu Y, Cooper R, et al. Evaluation of plasmid DNA removal from lentiviral vectors by benzonase treatment. Hum Gene Ther. 2004; 15:221-226.
    • (2004) Hum Gene Ther. , vol.15 , pp. 221-226
    • Sastry, L.1    Xu, Y.2    Cooper, R.3
  • 37
    • 0031575431 scopus 로고    scopus 로고
    • Change in coreceptor use correlates with disease progression in HIV-1-infected individuals
    • Connor RI, Sheridan KE, Ceradini D, et al. Change in coreceptor use correlates with disease progression in HIV-1-infected individuals. J Exp Med. 1997;185:621-628.
    • (1997) J Exp Med. , vol.185 , pp. 621-628
    • Connor, R.I.1    Sheridan, K.E.2    Ceradini, D.3
  • 38
    • 0037039380 scopus 로고    scopus 로고
    • HIV-1 escape from a small molecule CCR5-specific entry inhibitor does not involve CXCR4 use
    • Trkola A, Kuhmann SE, Strizki JM, et al. HIV-1 escape from a small molecule, CCR5-specific entry inhibitor does not involve CXCR4 use. Proc Natl Acad Sci USA. 2002;99:395-400.
    • (2002) Proc Natl Acad Sci USA. , vol.99 , pp. 395-400
    • Trkola, A.1    Kuhmann, S.E.2    Strizki, J.M.3
  • 39
    • 77950196300 scopus 로고    scopus 로고
    • Differential inhibition of human immunodeficiency virus type 1 in peripheral blood mononuclear cells and TZM-bl cells by endotoxin-mediated chemokine and gamma inter-feron production
    • Geonnotti AR, Bilska M, Yuan X, et al. Differential inhibition of human immunodeficiency virus type 1 in peripheral blood mononuclear cells and TZM-bl cells by endotoxin-mediated chemokine and gamma inter-feron production. AIDS Res Hum Retroviruses. 2010;26:279-291.
    • (2010) AIDS Res Hum Retroviruses. , vol.26 , pp. 279-291
    • Geonnotti, A.R.1    Bilska, M.2    Yuan, X.3
  • 40
    • 79958098668 scopus 로고    scopus 로고
    • A time-of-drug addition approach to target identification of antiviral compounds
    • Daelemans D, Pauwels R, De Clercq E, et al. A time-of-drug addition approach to target identification of antiviral compounds. Nat Protoc. 2011;6:925-933.
    • (2011) Nat Protoc. , vol.6 , pp. 925-933
    • Daelemans, D.1    Pauwels, R.2    De Clercq, E.3
  • 41
    • 66349110542 scopus 로고    scopus 로고
    • Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state
    • Haim H, Si Z, Madani N, et al. Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state. PLoS Pathog. 2009;5:e1000360.
    • (2009) PLoS Pathog. , vol.5
    • Haim, H.1    Si, Z.2    Madani, N.3
  • 42
    • 33745203490 scopus 로고    scopus 로고
    • Distribution and three-dimensional structure of AIDS virus envelope spikes
    • Zhu P, Liu J, Bess J Jr, et al. Distribution and three-dimensional structure of AIDS virus envelope spikes. Nature. 2006;441:847-852.
    • (2006) Nature. , vol.441 , pp. 847-852
    • Zhu, P.1    Liu, J.2    Bess Jr., J.3
  • 43
    • 62849099645 scopus 로고    scopus 로고
    • Effects of mutations on HIV-1 infec-tivity and neutralization involving the conserved NNNT amino acid sequence in the gp120 V3 loop
    • Polzer S, Muller H, Schreiber M. Effects of mutations on HIV-1 infec-tivity and neutralization involving the conserved NNNT amino acid sequence in the gp120 V3 loop. FEBS Lett. 2009;583:1201-1206.
    • (2009) FEBS Lett. , vol.583 , pp. 1201-1206
    • Polzer, S.1    Muller, H.2    Schreiber, M.3
  • 44
    • 18244422922 scopus 로고    scopus 로고
    • The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-.2 mannose residues on the outer face of gp120
    • Scanlan CN, Pantophlet R, Wormald MR, et al. The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-.2 mannose residues on the outer face of gp120. J Virol. 2002;76:7306-7321.
    • (2002) J Virol. , vol.76 , pp. 7306-7321
    • Scanlan, C.N.1    Pantophlet, R.2    Wormald, M.R.3
  • 45
    • 84864603281 scopus 로고    scopus 로고
    • Structural mechanism of tri-meric HIV-1 envelope glycoprotein activation
    • Tran EE, Borgnia MJ, Kuybeda O, et al. Structural mechanism of tri-meric HIV-1 envelope glycoprotein activation. PLoS Pathog. 2012;8: e1002797.
    • (2012) PLoS Pathog. , vol.8
    • Tran, E.E.1    Borgnia, M.J.2    Kuybeda, O.3
  • 46
    • 1642377363 scopus 로고    scopus 로고
    • The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4
    • Pugach P, Kuhmann SE, Taylor J, et al. The prolonged culture of human immunodeficiency virus type 1 in primary lymphocytes increases its sensitivity to neutralization by soluble CD4. Virology. 2004;321:8-22.
    • (2004) Virology. , vol.321 , pp. 8-22
    • Pugach, P.1    Kuhmann, S.E.2    Taylor, J.3
  • 47
    • 11144227042 scopus 로고    scopus 로고
    • Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycopro-tein gp41 to neutralize HIV-1
    • Zwick MB, Jensen R, Church S, et al. Anti-human immunodeficiency virus type 1 (HIV-1) antibodies 2F5 and 4E10 require surprisingly few crucial residues in the membrane-proximal external region of glycopro-tein gp41 to neutralize HIV-1. J Virol. 2005;79:1252-1261.
    • (2005) J Virol. , vol.79 , pp. 1252-1261
    • Zwick, M.B.1    Jensen, R.2    Church, S.3
  • 48
    • 79959845498 scopus 로고    scopus 로고
    • Contribution of intrinsic reactivity of the HIV-1 envelope glycoproteins to CD4-independent infection and global inhibitor sensitivity
    • Haim H, Strack B, Kassa A, et al. Contribution of intrinsic reactivity of the HIV-1 envelope glycoproteins to CD4-independent infection and global inhibitor sensitivity. PLoS Pathog. 2011;7:e1002101.
    • (2011) PLoS Pathog. , vol.7
    • Haim, H.1    Strack, B.2    Kassa, A.3
  • 49
    • 84887625124 scopus 로고    scopus 로고
    • HIV: Antibodies advance the search for a cure
    • Picker LJ, Deeks SG. HIV: antibodies advance the search for a cure. Nature. 2013;503:207-208.
    • (2013) Nature. , vol.503 , pp. 207-208
    • Picker, L.J.1    Deeks, S.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.