IL-15 regulates Bcl-2 family members Bim and Mcl-1 through JAK/STAT and PI3K/AKT pathways in T cells

European Journal of Immunology

Volumn 44, Issue 8, 2014, Pages 2500-2507

  Shenoy, Aparna R ^a   Kirschnek, Susanne ^a   Häcker, Georg ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Apoptosis; Bim; Common gamma chain cytokines; Mcl 1; T cells

Indexed keywords

BIM PROTEIN; CD3 ANTIGEN; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 7; JANUS KINASE; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN MCL 1; RECOMBINANT CYTOKINE; STAT PROTEIN; STAT5 PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CONTROLLED STUDY; DOWN REGULATION; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PROCESSING; PROTEIN STABILITY; SIGNAL TRANSDUCTION; T LYMPHOCYTE; UPREGULATION;

APOPTOSIS; BIM; COMMON GAMMA CHAIN CYTOKINES; MCL-1; T CELLS;

ANIMALS; ANTIGENS, CD3; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL SURVIVAL; INTERLEUKIN-15; INTERLEUKIN-2; INTERLEUKIN-7; JANUS KINASES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; T-LYMPHOCYTES;

EID: 84906082010     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201344238     Document Type: Article

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