Rheumatoid arthritis bone fragility is associated with upregulation of IL17 and DKK1 gene expression

Clinical Reviews in Allergy and Immunology

Volumn 47, Issue 1, 2014, Pages 38-45

  Caetano Lopes, Joana ^a   Rodrigues, Ana ^a,b   Lopes, Ana ^a   Vale, Ana C ^c   Pitts Kiefer, Michael A ^d   Vidal, Bruno ^a   Perpétuo, Inês P ^a   Monteiro, Jacinto ^b   Konttinen, Yrjö T ^e   Vaz, Maria F ^c   Nazarian, Ara ^d   Canhão, Helena ^a,b   Fonseca, João E ^a,b  

^a INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^b Rheumatology and Bone Metabolic Diseases Department Lisbon Academic Medical Centre ^*  (Portugal)

^c INSTITUTO SUPERIOR TÉCNICO   (Portugal)

^d HARVARD MEDICAL SCHOOL   (United States)

^e HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Bone turnover; IL17; Osteoblast; Rheumatoid arthritis; Wnt pathway

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ALKALINE PHOSPHATASE; BETA CATENIN; CALCIUM; DICKKOPF 1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 16; INTERLEUKIN 17; INTERLEUKIN 1BETA; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PHOSPHORUS; TRANSCRIPTION FACTOR RUNX2; TUMOR NECROSIS FACTOR; WNT10B PROTEIN; DKK1 PROTEIN, HUMAN; DKK2 PROTEIN, HUMAN; INFLAMMATION MEDIATORS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-17; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; LRP6 PROTEIN, HUMAN; PROTO-ONCOGENE PROTEINS; TRANSCRIPTOME; WNT PROTEINS; WNT10B PROTEIN, HUMAN;

AGED; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; BODY MASS; BONE DENSITY; BONE FRAGILITY; BONE MASS; BONE REMODELING; BONE TURNOVER; CALCIUM BLOOD LEVEL; CALCIUM METABOLISM; COMPRESSION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HIP ARTHROPLASTY; HIP FRACTURE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; OSTEOCLASTOGENESIS; OSTEOLYSIS; PHOSPHATE BLOOD LEVEL; PRIMARY OSTEOPOROSIS; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; UPREGULATION; WNT SIGNALING PATHWAY; ARTHRITIS, RHEUMATOID; BIOSYNTHESIS; BLOOD; BONE RESORPTION; CASE-CONTROL STUDIES; COHORT STUDIES; COMPARATIVE STUDY; DOWN-REGULATION; GENE EXPRESSION REGULATION; GENETICS; HUMANS; METABOLISM; MIDDLE AGED; MOLECULAR TARGETED THERAPY; OSTEOPOROSIS; UP-REGULATION;

AGED; ARTHRITIS, RHEUMATOID; BETA CATENIN; BONE RESORPTION; CASE-CONTROL STUDIES; COHORT STUDIES; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION MEDIATORS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-17; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-6; MALE; MIDDLE AGED; MOLECULAR TARGETED THERAPY; OSTEOPOROSIS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTOME; UP-REGULATION; WNT PROTEINS;

EID: 84906080781     PISSN: 10800549     EISSN: 15590267     Source Type: Journal    
DOI: 10.1007/s12016-013-8366-y     Document Type: Article

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