-
1
-
-
77649184739
-
The regulation of IL-10 production by immune cells
-
Saraiva, M., and O'Garra, A. (2010) The regulation of IL-10 production by immune cells. Nat. Rev. Immunol. 10, 170-181
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 170-181
-
-
Saraiva, M.1
O'Garra, A.2
-
2
-
-
33644506745
-
Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt
-
Pengal, R. A., Ganesan, L. P., Wei, G., Fang, H., Ostrowski, M. C., and Tridandapani, S. (2006) Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt. Mol. Immunol. 43, 1557-1564
-
(2006)
Mol. Immunol.
, vol.43
, pp. 1557-1564
-
-
Pengal, R.A.1
Ganesan, L.P.2
Wei, G.3
Fang, H.4
Ostrowski, M.C.5
Tridandapani, S.6
-
3
-
-
80155142474
-
Rapamycin passes the torch: A new generation of mTOR inhibitors
-
Benjamin, D., Colombi, M., Moroni, C., and Hall, M. N. (2011) Rapamycin passes the torch: a new generation of mTOR inhibitors. Nat. Rev. Drug Discov. 10, 868-880
-
(2011)
Nat. Rev. Drug Discov.
, vol.10
, pp. 868-880
-
-
Benjamin, D.1
Colombi, M.2
Moroni, C.3
Hall, M.N.4
-
4
-
-
0242496906
-
Phosphatidic Acid Regulates Systemic Inflammatory Responses by Modulating the Akt-Mammalian Target of Rapamycin-p70 S6 Kinase 1 Pathway
-
DOI 10.1074/jbc.M303789200
-
Lim, H. K., Choi, Y. A., Park, W., Lee, T., Ryu, S. H., Kim, S. Y., Kim, J. R., Kim, J. H., and Baek, S. H. (2003) Phosphatidic acid regulates systemic inflammatory responses by modulating the Akt-mammalian target of rapamycin-p70 S6 kinase 1 pathway. J. Biol. Chem. 278, 45117-45127 (Pubitemid 37432644)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.46
, pp. 45117-45127
-
-
Lim, H.-K.1
Choi, Y.-A.2
Park, W.3
Lee, T.4
Ryu, S.H.5
Kim, S.-Y.6
Kim, J.-R.7
Kim, J.-H.8
Baek, S.-H.9
-
5
-
-
33750325725
-
S6k1- and βTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth
-
DOI 10.1126/science.1130276
-
Dorrello, N. V., Peschiaroli, A., Guardavaccaro, D., Colburn, N. H., Sherman, N. E., and Pagano, M. (2006) S6K1- and βTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science 314, 467-471 (Pubitemid 44628968)
-
(2006)
Science
, vol.314
, Issue.5798
, pp. 467-471
-
-
Dorrello, N.V.1
Peschiaroli, A.2
Guardavaccaro, D.3
Colburn, N.H.4
Sherman, N.E.5
Pagano, M.6
-
6
-
-
75649113377
-
Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21
-
Sheedy, F. J., Palsson-McDermott, E., Hennessy, E. J., Martin, C., O'Leary, J. J., Ruan, Q., Johnson, D. S., Chen, Y., and O'Neill, L. A. (2010) Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21. Nat. Immunol. 11, 141-147
-
(2010)
Nat. Immunol.
, vol.11
, pp. 141-147
-
-
Sheedy, F.J.1
Palsson-McDermott, E.2
Hennessy, E.J.3
Martin, C.4
O'Leary, J.J.5
Ruan, Q.6
Johnson, D.S.7
Chen, Y.8
O'Neill, L.A.9
-
7
-
-
0038209450
-
Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation
-
DOI 10.1038/sj.onc.1206433
-
Yang, H. S., Knies, J. L., Stark, C., and Colburn, N. H. (2003) Pdcd4 suppresses tumor phenotype in JB6 cells by inhibiting AP-1 transactivation. Oncogene 22, 3712-3720 (Pubitemid 36760733)
-
(2003)
Oncogene
, vol.22
, Issue.24
, pp. 3712-3720
-
-
Yang, H.-S.1
Knies, J.L.2
Stark, C.3
Colburn, N.H.4
-
8
-
-
0037216626
-
The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation
-
DOI 10.1128/MCB.23.1.26-37.2003
-
Yang, H. S., Jansen, A. P., Komar, A. A., Zheng, X., Merrick, W. C., Costes, S., Lockett, S. J., Sonenberg, N., and Colburn, N. H. (2003) The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation. Mol. Cell. Biol. 23, 26-37 (Pubitemid 36008498)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.1
, pp. 26-37
-
-
Yang, H.-S.1
Jansen, A.P.2
Komar, A.A.3
Zheng, X.4
Merrick, W.C.5
Costes, S.6
Lockett, S.J.7
Sonenberg, N.8
Colburn, N.H.9
-
9
-
-
59649094064
-
Structural basis for translational inhibition by the tumour suppressor Pdcd4
-
Loh, P. G., Yang, H. S., Walsh, M. A., Wang, Q., Wang, X., Cheng, Z., Liu, D., and Song, H. (2009) Structural basis for translational inhibition by the tumour suppressor Pdcd4. EMBO J. 28, 274-285
-
(2009)
EMBO J.
, vol.28
, pp. 274-285
-
-
Loh, P.G.1
Yang, H.S.2
Walsh, M.A.3
Wang, Q.4
Wang, X.5
Cheng, Z.6
Liu, D.7
Song, H.8
-
10
-
-
33751580087
-
Translational regulation of autoimmune inflammation and lymphoma genesis by programmed cell death 4
-
Hilliard, A., Hilliard, B., Zheng, S. J., Sun, H., Miwa, T., Song, W., Göke, R., and Chen, Y. H. (2006) Translational regulation of autoimmune inflammation and lymphoma genesis by programmed cell death 4. J. Immunol. 177, 8095-8102 (Pubitemid 44846328)
-
(2006)
Journal of Immunology
, vol.177
, Issue.11
, pp. 8095-8102
-
-
Billiard, A.1
Hilliard, B.2
Zheng, S.-J.3
Sun, H.4
Miwa, T.5
Song, W.6
Goke, R.7
Chen, Y.H.8
-
11
-
-
62549164363
-
Crystal structure of the eIF4A-PDCD4 complex
-
Chang, J. H., Cho, Y. H., Sohn, S. Y., Choi, J. M., Kim, A., Kim, Y. C., Jang, S. K., and Cho, Y. (2009) Crystal structure of the eIF4A-PDCD4 complex. Proc. Natl. Acad. Sci. U.S.A. 106, 3148-3153
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 3148-3153
-
-
Chang, J.H.1
Cho, Y.H.2
Sohn, S.Y.3
Choi, J.M.4
Kim, A.5
Kim, Y.C.6
Jang, S.K.7
Cho, Y.8
-
12
-
-
66149147100
-
Programmed cell death protein 4 down-regulates Y-box binding protein-1 expression via a direct interaction with Twist1 to suppress cancer cell growth
-
Shiota, M., Izumi, H., Tanimoto, A., Takahashi, M., Miyamoto, N., Kashiwagi, E., Kidani, A., Hirano, G., Masubuchi, D., Fukunaka, Y., Yasuniwa, Y., Naito, S., Nishizawa, S., Sasaguri, Y., and Kohno, K. (2009) Programmed cell death protein 4 down-regulates Y-box binding protein-1 expression via a direct interaction with Twist1 to suppress cancer cell growth. Cancer Res. 69, 3148-3156
-
(2009)
Cancer Res.
, vol.69
, pp. 3148-3156
-
-
Shiota, M.1
Izumi, H.2
Tanimoto, A.3
Takahashi, M.4
Miyamoto, N.5
Kashiwagi, E.6
Kidani, A.7
Hirano, G.8
Masubuchi, D.9
Fukunaka, Y.10
Yasuniwa, Y.11
Naito, S.12
Nishizawa, S.13
Sasaguri, Y.14
Kohno, K.15
-
13
-
-
0025963454
-
The M-twist gene of Mus is expressed in subsets of mesodermal cells and is closely related to the Xenopus X-twi and the Drosophila twist genes
-
Wolf, C., Thisse, C., Stoetzel, C., Thisse, B., Gerlinger, P., and Perrin- Schmitt, F. (1991) The M-twist gene of Mus is expressed in subsets of mesodermal cells and is closely related to the Xenopus X-twi and the Drosophila twist genes. Dev. Biol. 143, 363-373 (Pubitemid 121004661)
-
(1991)
Developmental Biology
, vol.143
, Issue.2
, pp. 363-373
-
-
Wolf, C.1
Thisse, C.2
Stoetzel, C.3
Thisse, B.4
Gerlinger, P.5
Perrin-Schmitt, F.6
-
14
-
-
0028829831
-
Dermo-1: A novel twist-related bHLH protein expressed in the developing dermis
-
Li, L., Cserjesi, P., and Olson, E. N. (1995) Dermo-1: a novel twist-related bHLH protein expressed in the developing dermis. Dev. Biol. 172, 280-292
-
(1995)
Dev. Biol.
, vol.172
, pp. 280-292
-
-
Li, L.1
Cserjesi, P.2
Olson, E.N.3
-
15
-
-
58149169001
-
Twist-2 controls myeloid lineage development and function
-
Sharabi, A. B., Aldrich, M., Sosic, D., Olson, E. N., Friedman, A. D., Lee, S. H., and Chen, S. Y. (2008) Twist-2 controls myeloid lineage development and function. PLoS Biol. 6, e316
-
(2008)
PLoS Biol.
, vol.6
-
-
Sharabi, A.B.1
Aldrich, M.2
Sosic, D.3
Olson, E.N.4
Friedman, A.D.5
Lee, S.H.6
Chen, S.Y.7
-
16
-
-
77958126087
-
A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation
-
Haidinger, M., Poglitsch, M., Geyeregger, R., Kasturi, S., Zeyda, M., Zlabinger, G. J., Pulendran, B., Hörl, W. H., Säemann, M. D., and Weichhart, T. (2010) A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation. J. Immunol. 185, 3919-3931
-
(2010)
J. Immunol.
, vol.185
, pp. 3919-3931
-
-
Haidinger, M.1
Poglitsch, M.2
Geyeregger, R.3
Kasturi, S.4
Zeyda, M.5
Zlabinger, G.J.6
Pulendran, B.7
Hörl, W.H.8
Säemann, M.D.9
Weichhart, T.10
-
17
-
-
80053144773
-
Inflammation-induced loss of Pdcd4 is mediated by phosphorylation- dependent degradation
-
Schmid, T., Bajer, M. M., Blees, J. S., Eifler, L. K., Milke, L., Rübsamen, D., Schulz, K., Weigert, A., Baker, A. R., Colburn, N. H., and Brüne, B. (2011) Inflammation-induced loss of Pdcd4 is mediated by phosphorylation-dependent degradation. Carcinogenesis 32, 1427-1433
-
(2011)
Carcinogenesis
, vol.32
, pp. 1427-1433
-
-
Schmid, T.1
Bajer, M.M.2
Blees, J.S.3
Eifler, L.K.4
Milke, L.5
Rübsamen, D.6
Schulz, K.7
Weigert, A.8
Baker, A.R.9
Colburn, N.H.10
Brüne, B.11
-
18
-
-
40449091284
-
Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion
-
DOI 10.1158/0008-5472.CAN-07-1719
-
Schmid, T., Jansen, A. P., Baker, A. R., Hegamyer, G., Hagan, J. P., and Colburn, N. H. (2008) Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion. Cancer Res. 68, 1254-1260 (Pubitemid 351346830)
-
(2008)
Cancer Research
, vol.68
, Issue.5
, pp. 1254-1260
-
-
Schmid, T.1
Jansen, A.P.2
Baker, A.R.3
Hegamyer, G.4
Hagan, J.P.5
Colburn, N.H.6
-
19
-
-
0038446051
-
Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide
-
Martin, M., Schifferle, R. E., Cuesta, N., Vogel, S. N., Katz, J., and Michalek, S. M. (2003) Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide. J. Immunol. 171, 717-725 (Pubitemid 36871381)
-
(2003)
Journal of Immunology
, vol.171
, Issue.2
, pp. 717-725
-
-
Martin, M.1
Schifferle, R.E.2
Cuesta, N.3
Vogel, S.N.4
Katz, J.5
Michalek, S.M.6
-
20
-
-
67349217332
-
Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-α expression in macrophages by reducing IL-10 expression
-
Baker, A. K., Wang, R., Mackman, N., and Luyendyk, J. P. (2009) Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-α expression in macrophages by reducing IL-10 expression. Mol. Immunol. 46, 2249-2255
-
(2009)
Mol. Immunol.
, vol.46
, pp. 2249-2255
-
-
Baker, A.K.1
Wang, R.2
Mackman, N.3
Luyendyk, J.P.4
-
21
-
-
54949109311
-
The TSC-mTOR signaling pathway regulates the innate inflammatory response
-
Weichhart, T., Costantino, G., Poglitsch, M., Rosner, M., Zeyda, M., Stuhlmeier, K. M., Kolbe, T., Stulnig, T. M., Hörl, W. H., Hengstschläger, M., Müller, M., and Säemann, M. D. (2008) The TSC-mTOR signaling pathway regulates the innate inflammatory response. Immunity 29, 565-577
-
(2008)
Immunity
, vol.29
, pp. 565-577
-
-
Weichhart, T.1
Costantino, G.2
Poglitsch, M.3
Rosner, M.4
Zeyda, M.5
Stuhlmeier, K.M.6
Kolbe, T.7
Stulnig, T.M.8
Hörl, W.H.9
Hengstschläger, M.10
Müller, M.11
Säemann, M.D.12
-
22
-
-
79955548609
-
Convergence of the mammalian target of rapamycin complex 1- and glycogen synthase kinase 3-β-signaling pathways regulates the innate inflammatory response
-
Wang, H., Brown, J., Gu, Z., Garcia, C. A., Liang, R., Alard, P., Beurel, E., Jope, R. S., Greenway, T., and Martin, M. (2011) Convergence of the mammalian target of rapamycin complex 1- and glycogen synthase kinase 3-β-signaling pathways regulates the innate inflammatory response. J. Immunol. 186, 5217-5226
-
(2011)
J. Immunol.
, vol.186
, pp. 5217-5226
-
-
Wang, H.1
Brown, J.2
Gu, Z.3
Garcia, C.A.4
Liang, R.5
Alard, P.6
Beurel, E.7
Jope, R.S.8
Greenway, T.9
Martin, M.10
-
23
-
-
14844340837
-
The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages
-
Cao, S., Liu, J., Song, L., and Ma, X. (2005) The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages. J. Immunol. 174, 3484-3492 (Pubitemid 40354056)
-
(2005)
Journal of Immunology
, vol.174
, Issue.6
, pp. 3484-3492
-
-
Cao, S.1
Liu, J.2
Song, L.3
Ma, X.4
-
24
-
-
0034577944
-
Toll-like receptor 2-mediated NF-κB activation requires a Rac1-dependent pathway
-
Arbibe, L., Mira, J. P., Teusch, N., Kline, L., Guha, M., Mackman, N., Godowski, P. J., Ulevitch, R. J., and Knaus, U. G. (2000) Toll-like receptor 2-mediated NF-κB activation requires a Rac1-dependent pathway. Nat. Immunol. 1, 533-540
-
(2000)
Nat. Immunol.
, vol.1
, pp. 533-540
-
-
Arbibe, L.1
Mira, J.P.2
Teusch, N.3
Kline, L.4
Guha, M.5
Mackman, N.6
Godowski, P.J.7
Ulevitch, R.J.8
Knaus, U.G.9
-
25
-
-
7544225495
-
Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling
-
DOI 10.1038/nsmb847
-
Sarkar, S. N., Peters, K. L., Elco, C. P., Sakamoto, S., Pal, S., and Sen, G. C. (2004) Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling. Nat. Struct. Mol. Biol. 11, 1060-1067 (Pubitemid 39453334)
-
(2004)
Nature Structural and Molecular Biology
, vol.11
, Issue.11
, pp. 1060-1067
-
-
Sarkar, S.N.1
Peters, K.L.2
Elco, C.P.3
Sakamoto, S.4
Pal, S.5
Sen, G.C.6
-
26
-
-
67651183597
-
Mal connects TLR2 to PI3Kinase activation and phagocyte polarization
-
Santos-Sierra, S., Deshmukh, S. D., Kalnitski, J., Küenzi, P., Wymann, M. P., Golenbock, D. T., and Henneke, P. (2009) Mal connects TLR2 to PI3Kinase activation and phagocyte polarization. EMBO J. 28, 2018-2027
-
(2009)
EMBO J.
, vol.28
, pp. 2018-2027
-
-
Santos-Sierra, S.1
Deshmukh, S.D.2
Kalnitski, J.3
Küenzi, P.4
Wymann, M.P.5
Golenbock, D.T.6
Henneke, P.7
-
27
-
-
0032412057
-
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
-
Sellon, R. K., Tonkonogy, S., Schultz, M., Dieleman, L. A., Grenther, W., Balish, E., Rennick, D. M., and Sartor, R. B. (1998) Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infection and immunity 66, 5224-5231 (Pubitemid 29044613)
-
(1998)
Infection and Immunity
, vol.66
, Issue.11
, pp. 5224-5231
-
-
Sellon, R.K.1
Tonkonogy, S.2
Schultz, M.3
Dieleman, L.A.4
Grenther, W.5
Balish, E.6
Rennick, D.M.7
Sartor, R.B.8
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