Are extremes of consumption in eating disorders related to an altered balance between reward and inhibition?

Frontiers in Behavioral Neuroscience

Volumn 8, Issue DEC, 2014, Pages

  Wierenga, Christina E ^a,b   Ely, Alice ^a   Bischoff Grethe, Amanda ^a   Bailer, Ursula F ^a,c   Simmons, Alan N ^a,b   Kaye, Walter H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Anorexia nervosa; Bulimia nervosa; Cognitive control; Eating disorders; Gustatory processing; Inhibition; Reward processing

Indexed keywords

ANOREXIA NERVOSA; ANTERIOR CINGULATE; ARTICLE; BEHAVIOR CONTROL; BULIMIA; CONNECTOME; DSM-5; EATING DISORDER; EXECUTIVE FUNCTION; FOOD INTAKE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; INHIBITION (PSYCHOLOGY); INSULA; NEUROBIOLOGY; NEUROIMAGING; NEUROPHYSIOLOGY; NONHUMAN; OBSESSIVE COMPULSIVE DISORDER; REWARD; SELF CONTROL; VENTROMEDIAL PREFRONTAL CORTEX;

EID: 84905906899     PISSN: 16625153     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnbeh.2014.00410     Document Type: Article

References (172)

1. Abraham, S., and Beaumont, P. (1982). How patients describe bulimia or binge eating. Psychol. Med. 12, 625-635. doi: 10.1017/S0033291700055732
2. American Psychiatric Association. (2013). Diagnostic and Statistical Manual of Mental Disorders, 5th Edn. Washington, DC: APA.
3. Anderluh, M. B., Tchanturia, K., Rabe-Hesketh, S., and Treasure, J. (2003). Childhood obsessive-compulsive personality traits in adult women with eating disorders: defining a broader eating disorder phenotype. Am. J. Psychiatry 160, 242-247. doi:10.1176/appi.ajp.160.2.242
4. Avena, N., Borcarsly, M., and Hoebel, B. (2012). Animal models of sugar and fat bingeing: relationship to food addiction and increased body weight. Methods Mol. Biol. 829, 351-365. doi:10.1007/978-1-61779-458-2_23
5. Beaton, G., Milner, J., McGuire, V., Feather, T., and Little, J. (1979). Source of variance in 24-hour dietary recall data: implications for nutrition study design and interpretation. Am. J. Clin. Nutr. 32, 2546-2559.
6. Berrettini, W. (2000). Genetics of psychiatric disease. Annu. Rev. Med. 51, 465-479. doi:10.1146/annurev.med.51.1.465
7. Bischoff-Grethe, A., McCurdy, D., Grenesko-Stevens, E., Irvine, L., Wagner, A., Yau, W.-Y., et al. (2013). Altered brain response to reward and punishment in adolescents with anorexia nervosa. Psychiatry Res. 214, 331-340. doi:10.1016/j.pscychresns.2013.07.004
8. Boeka, A. L., and Lokken, K. L. (2006). The Iowa gambling task as a measure of decision making in women with bulimia nervosa. J. Int. Neuropsycohol. Soc. 12, 741-745. doi:10.1017/S1355617706060887
9. Bohon, C., and Stice, E. (2011). Reward abnormalities among women with full and subthreshold bulimia nervosa: a functional magnetic resonance imaging study. Int. J. Eat. Disord. 44, 585-595. doi:10.1002/eat.20869
10. Boyar, R. K., Katz, J., Finkelstein, J. W., Kapen, S., Weiner, H., Weitzman, E. D., et al. (1974). Anorexia nervosa. Immaturity of the 24-hour luteinizing hormone secretory pattern. N. Engl. J. Med. 291, 861-865. doi:10.1056/NEJM197410242911701
11. Brockmeyer, T., Skunde, M., Wu, M., Bresslein, E., Rudofsky, G., Herzog, W., et al. (2013). Difficulties in emotion regulation across the spectrum of eating disorders. Compr. Psychiatry 55, 565-571. doi:10.1016/j.comppsych.2013.12.001
12. Brogan, A., Hevey, D., and Pignatti, R. (2010). Anorexia, bulimia, and obesity: shared decision making deficits on the Iowa gambling task (IGT). J. Int. Neuropsychol. Soc. 16, 711-715. doi:10.1017/S1355617710000354
13. Brooks, S., O'Daly, O., Uher, R., Frederich, H.-C., Giampietro, V., Brammer, M., et al. (2011). Differential neural responses to food images in women with bulimia versus anorexia nervosa. PLoS ONE 6:e22259. doi:10.1371/journal.pone.0022259
14. Bruce, A., Martin, L., and Savage, C. (2011). Neural correlates of pediatric obesity. Prev. Med. 52(Suppl. 1), S29-S35. doi:10.1016/j.ypmed.2011.01.018
15. Bulik, C., Hebebrand, J., Keski-Rahkonen, A., Klump, K., Reichborn-Kjennerud, K. S., Mazzeo, S., et al. (2007). Genetic epidemiology, endophenotypes, and eating disorder classification. Int. J. Eat. Disord. 40, S52-S60. doi:10.1002/eat.20398
16. Bulik, C., Sullivan, P. F., Tozzi, F., Furberg, H., Lichtenstein, P., and Pedersen, N. L. (2006). Prevalence, heritability and prospective risk factors for anorexia nervosa. Arch. Gen. Psychiatry 63, 305-312. doi:10.1001/archpsyc.63.3.305
17. Burger, K., and Stice, E. (2011). Variability in reward responsivity and obesity: evidence from brain imaging studies. Curr. Drug Abuse Rev. 4, 182-189. doi:10.2174/1874473711104030182
18. Calero-Elvira, A., Krug, I., Davis, K., Lopez, C., Fernandez-Aranda, F., and Treasure, J. (2009). Meta-analysis on drugs in people with eating disorders. Eur. Eat. Disord. Rev. 17, 243-259. doi:10.1002/erv.936
19. Carnell, S., Gibson, C., Benson, L., Ochner, C., and Geliebter, A. (2012). Neuroimaging and obesity: current knowledge and future directions. Obes. Res. 13, 43-56. doi:10.1111/j.1467-789X.2011.00927.x
20. Carver, C., and White, T. (1994). Behavioral inhibition, behavioral activation, and affective responses to impending reward and punishment: the BIS/BAS scales. J. Pers. Soc. Psychol. 67, 319-333. doi:10.1037/0022-3514.67.2.319
21. Cassin, S., and von Ranson, K. (2005). Personality and eating disorders: a decade in review. Clin. Psychol. Rev. 25, 895-916. doi:10.1016/j.cpr.2005.04.012
22. Chan, T. A., Ahn, W. Y., Bates, J. E., Busemeyer, J. R., Guillaume, S., Redgrave, G. W., et al. (2014). Differential impairments underlying decision making in anorexia nervosa and bulimia nervosa: a cognitive modeling analysis.Int. J. Eat. Disord. 47, 157-167. doi:10.1002/eat.22223
23. Claes, L., Klonsky, E., Muehlenkamp, J., Kuppens, P., and Vandereycken, W. (2010). The affect-regulation function of nonsuicidal self-injury in eating-disordered patients: which affect states are regulated? Compr. Psychiatry 51, 386-392. doi:10.1016/j.comppsych.2009.09.001
24. Claes, L., Mitchell, J., and Vandereycken, W. (2012). Out of control? Inhibition processes in eating disorders from a personality and cognitive perspective. Int. J. Eat. Disord. 45, 407-414. doi:10.1002/eat.20966
25. Claes, L., Nederkoorn, C., Vandereycken, W., Guerrieri, R., and Vertommen, H. (2006). Impulsiveness and lack of inhibitory control in eating disorders. Eat. Behav. 7, 196-203. doi:10.1016/j.eatbeh.2006.05.001
26. Clinton, D., Button, E., Norring, C., and Palmer, R. (2004). Cluster analysis of key diagnositic variables from two independent samples of eating-disorder patients: evidence for a consistent pattern. Psychol. Med. 34, 1035-1045. doi:10.1017/S0033291703001508
27. Cloninger, C., Przybeck, T., Svrakic, D., and Wetzel, R. (1994). The Temperament and Character Inventory (TCI): A Guide to Its Development and Use. St. Louis, MO: Center for Psychobiology of Personality, 19-28.
28. Cowdrey, F., Park, R., Harmer, C., and McCabe, C. (2011). Increased neural processing of rewarding and aversive food stimuli in recovered anorexia nervosa. Biol. Psychiatry 70, 736-743. doi:10.1016/j.biopsych.2011.05.028
29. Craig, A. (2004). Human feelings: why are some more aware than others? Trends Cogn. Sci. (Regul. Ed.) 8, 239-241. doi:10.1016/j.tics.2004.04.004
30. Craig, A. (2009). How do you feel - now? The anterior insula and human awareness. Nat. Rev. Neurosci. 10, 59-70. doi:10.1038/nrn2555
31. Craig, A. D. (2002). How do you feel? Interoception: the sense of the physiological condition of the body. Nat. Rev. Neurosci. 3, 655-666. doi:10.1038/nrn894
32. Crosby, R., Wonderlich, S., Engel, S., Simonich, H., Smyth, J., and Mitchell, J. (2009). Daily mood patterns and bulimic behaviors in the natural environment. Behav. Res. Ther. 47, 181-188. doi:10.1016/j.brat.2008.11.006
33. Delgado, M., Nystrom, L., Fissel, C., Noll, D., and Fiez, J. (2000). Tracking the hemodynamic responses to reward and punishment in the striatum. J. Neurophysiol. 84, 3072-3077.
34. Dietz, W. (1998). Health consequences of obesity in youth: childhood predictors of adult disease. Pediatrics 101(3 Pt 2), 518-525.
35. Dixon, L., Subar, A., Winderoff, L., Thompson, F., Kahle, L., and Potischman, N. (2006). Carotenoid and tocopherol estimates from the NCI diet history questionnaire are valid compared with multiple recalls and serum biomarkers.J. Nutr. 136, 3054-3061.
36. Epstein, L., Temple, J., Neaderhiser, B., Salis, R., Erbe, R., Leddy, J., et al. (2007). Food reinforcement, the dopamine D2 receptor genotype, and energy intake in obese and nonobese humans. Behav. Neurosci. 121, 877-886. doi:10.1037/0735-7044.121.5.877
37. Epstein, L., Wright, S., Paluch, R., Leddy, J., Hawk, L., and Jaroni, J. (2004). Food hedonics and reinforcement as determinants of laboratory food intake in smokers. Physiol. Behav. 81, 511-517. doi:10.1016/j.physbeh.2004.02.015
38. Evans, E., and Rothbart, M. (2007). Developing a model for adult temperament. J. Res. Pers. 41, 868-888. doi:10.1016/j.jrp.2006.11.002
39. Fassino, S., Amianto, F., Gramaglia, C., Faccchini, F., and Abbate Daga, G. (2004). Temperament and character in eating disorders: ten years of studies. Eat. Weight Disord. 9, 81-90. doi:10.1007/BF03325050
40. Feil, J., Sheppard, D., Fitzgerald, P., Yucel, M., Lubman, D., and Bradshaw, J. (2010). Addiction, compulsive drug seeking, and the role of frontostriatal mechanisms in regulating inhibitory control. Neurosci. Biobehav. Rev. 35, 248-275. doi:10.1016/j.neubiorev.2010.03.001
41. Ferro, A., Brugnolo, A., De Leo, C., Dessi, B., Girtler, N., Morbelli, S., et al. (2005). Stroop interference task and single-photon emossion tomography in anorexia: a preliminary report. Int. J. Eat. Disord. 38, 323-329. doi:10.1002/eat.20203
42. Fischer, S., Smith, G., and Cyders, M. (2008). Another look at impulsivity: a meta-analytic review comparing specific dispositions to rash action in their relationship to bulimic symptoms. Clin. Psychol. Rev. 28, 1413-1425. doi:10.1016/j.cpr.2008.09.001
43. Frank, G. (2013). Altered brain reward circuits in eating disorders: chicken or egg? Curr. Psychiatry Rep. 15, 396. doi:10.1007/s11920-013-0396-x
44. 11C]raclopride. Biol. Psychiatry 58, 908-912. doi:10.1016/j.biopsych.2005.05.003
45. Frank, G., and Kaye, W. (2012). Current status of functional imaging in eating disorders. Int. J. Eat. Disord. 45, 723-736. doi:10.1002/eat.22016
46. Frank, G., Reynolds, J., Shott, M., and O'Reilly, R. (2011). Altered temporal difference learning in bulimia nervosa.Biol. Psychiatry 70, 728-735. doi:10.1016/j.biopsych.2011.05.011
47. Frank, G., Roblek, T., Shott, M., Jappe, L., Rollin, M., Hagman, J., et al. (2012a). Heightened fear of uncertainty in anorexia and bulimia nervosa. Int. J. Eat. Disord. 45, 227-232. doi:10.1002/eat.20929
48. Frank, G., Reynolds, J., Shott, M., Jappe, L., Yang, T., Tregellas, J., et al. (2012b). Anorexia nervosa and obesity are associated with opposite brain reward response. Neuropsychopharmacology 37, 2031-2046. doi:10.1038/npp.2012.51
49. Franken, I., Muris, P., and Georgieva, I. (2006). Gray's model of personality and addiction. Addict. Behav. 31, 399-403. doi:10.1016/j.addbeh.2005.05.022
50. Friederich, H., and Herzog, W. (2011). Cognitive-behavioral flexibility in anorexia nervosa. Curr. Top. Behav. Neurosci. 6, 111-123. doi:10.1007/7854_2010_83
51. Gadalla, T., and Piran, N. (2007). Co-occurrence of eating disorders and alcohol use disorders in women: a meta analysis. Arch. Womens Ment. Health 10, 133-140. doi:10.1007/s00737-007-0184-x
52. Garcia-Garcia, I., Narberhaus, A., Marqués-Iturria, I., Garolera, M., Rădoi, A., Segura, B., et al. (2013). Neural responses to visual food cues: insights from functional magnetic resonance imaging. Eur. Eat. Disord. Rev. 21, 89-98. doi:10.1002/erv.2216
53. Gazzillo, F., Lingiardi, V., Peloso, A., Giordani, S., Vesco, S., Zanna, V., et al. (2013). Personality subtypes in adolescents with anorexia nervosa. Compr. Psychiatry 54, 702-712. doi:10.1016/j.comppsych.2013.03.006
54. Gizewski, E., Rosenberger, C., de Greiff, A., Moll, A., Senf, W., Wanke, I., et al. (2010). Influence of satiety and subjective valence rating on cerebral activation patterns in response to visual stimulation with high-calorie stimuli among restrictive anorectic and control women. Neuropsychobiology 62, 182-192. doi:10.1159/000319360
55. Glashouwer, K., Bloot, L., Veenstra, E., Franken, I., and de Jong, P. (2014). Heightened sensitivity to punishment and reward in anorexia nervosa. Appetite 75C, 97-102. doi:10.1016/j.appet.2013.12.019
56. Godart, N., Perdereau, F., Rein, Z., Berthoz, S., Wallier, J., Jeammet, P., et al. (2007). Comorbidity studies of eating disorders and mood disorders. Critical review of the literature. J. Affect. Disord. 97, 37-49. doi:10.1016/j.jad.2006.06.023
57. Goldner, E., Srikameswaran, S., Schroeder, M., Livesley, W., and Birmingham, A. (1999). Dimensional assessment of personality pathology in patients with eating disorders. Psychiatry Res. 85, 151-159. doi:10.1016/S0165-1781(98)00145-0
58. Goldstein, R., and Volkow, N. D. (2002). Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. Am. J. Psychiatry 159, 1642-1652. doi:10.1176/appi.ajp.159.10.1642
59. Goldstone, A., Prechtl de Hernandez, C., Beaver, J., Muhammed, K., Croese, C., Bell, G., et al. (2009). Fasting biases brain reward systems towards high-calorie foods. Eur. J. Neurosci. 30, 1625-1635. doi:10.1111/j.1460-9568.2009.06949.x
60. Grupe, D., and Nitschke, J. (2013). Uncertainty and anticipation in anxiety: an integrated neurobiological and psychological perspective. Nat. Rev. Neurosci. 14, 488-501. doi:10.1038/nrn3524
61. Haase, L., Cerf-Ducastel, B., and Murphy, C. (2009). Cortical activation in response to pure taste stimuli during the physiological states of hunger and satiety. Neuroimage 44, 1008-1021. doi:10.1016/j.neuroimage.2008.09.044
62. Haber, S., and Knutson, B. (2010). The reward circuit: linking primate anatomy and human imaging.Neuropsychopharmacology 35, 4-26. doi:10.1038/npp.2009.129
63. Haedt-Matt, A., and Keel, P. (2011). Revisiting the affect regulation model of binge eating: a meta-analysis of studies using ecological momentary assessment. Psychol. Bull. 137, 660-681. doi:10.1037/a0023660
64. Harnishfeger, K., and Pope, R. (1996). Intending to forget: the development of cognitive inhibition in directed forgetting. J. Exp. Child Psychol. 62, 292-315. doi:10.1006/jecp.1996.0032
65. Harrison, A., O'Brien, N., Lopez, C., and Treasure, J. (2010). Sensitivity to reward and punishment in eating disorders. Psychiatry Res. 177, 1-11. doi:10.1016/j.psychres.2009.06.010
66. Harrison, A., Treasure, J., and Smillie, L. (2011). Approach and avoidance motivation in eating disorders.Psychiatry Res. 188, 396-401. doi:10.1016/j.psychres.2011.04.022
67. Herzog, D. B., Keller, M. B., Lavori, P. W., Kenny, G. M., and Sacks, N. R. (1992). The prevalence of personality disorders in 210 women with eating disorders. J. Clin. Psychiatry 53, 147-152.
68. Holliday, J., Landau, S., Collier, D., and Trasure, J. (2006). Do illness characteristics and familial risk differ between women with anorexia nervosa grouped on the basis of personality pathology? Psychol. Med. 36, 529-538. doi:10.1017/S0033291705006641
69. Holliday, J., Tchanturia, K., Landau, S., Collier, D. A., and Treasure, J. (2005). Is impaired set-shifting an endophenotype of anorexia nervosa? Am. J. Psychiatry 162, 2269-2275. doi:10.1176/appi.ajp.162.12.2269
70. Holsen, L., Lawson, E., Blum, K., Ko, E., Makris, N., and Fazeli, P. (2012). Food motivation circuitry hypoactivation related to hedonic and nonhedonic aspects of hunger and satiety in women with active anorexia nervosa and weight-restored women with anorexia nervosa. J. Psychiatry Neurosci. 37, 322-332. doi:10.1503/jpn.110156
71. Jappe, L., Frank, G., Shott, M., Rollin, M., Pryor, T., Hagman, J., et al. (2011). Heightened sensitivity to reward and punishment in anorexia nervosa. Int. J. Eat. Disord. 44, 317-324. doi:10.1002/eat.20815
72. Jimerson, D., and Wolfe, B. (2006). "Psychobiology of eating disorders," in Annual Review of Eating Disorders: Part 2 - 2006, eds S. Wonderlich, J. Mitchell, M. de Zwaan, and H. Steiger (Oxford: Radcliffe Publishing), 1-15.
73. Johnson, C., and Larson, R. (1982). Bulimia: an analysis of mood and behavior. Psychosom. Med. 44, 341-351. doi:10.1097/00006842-198209000-00003
74. Johnson, P., and Kenny, P. (2010). Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats. Nat. Neurosci. 13, 635-641. doi:10.1038/nn.2519
75. Karwautz, A., Troop, N. A., Rabe-Hesketh, S., Collier, D. A., and Treasure, J. L. (2003). Personality disorders and personality dimensions in anorexia nervosa. J. Pers. Disord. 17, 73-85. doi:10.1521/pedi.17.1.73.24057
76. Katzman, D. K., Lambe, E. K., Mikulis, D. J., Ridgley, J. N., Goldbloom, D. S., and Zipursky, R. B. (1996). Cerebral gray matter and white matter volume deficits in adolescent girls with anorexia nervosa. J. Pediatr. 129, 794-803. doi:10.1016/S0022-3476(96)70021-5
77. Kaye, W., Bulik, C., Thornton, L., Barbarich, N., Masters, K., Fichter, M., et al. (2004). Comorbidity of anxiety disorders with anorexia and bulimia nervosa. Am. J. Psychiatry 161, 2215-2221. doi:10.1176/appi.ajp.161.12.2215
78. Kaye, W., Fudge, J., and Paulus, M. (2009). New insight into symptoms and neurocircuit function of anorexia nervosa. Nat. Rev. Neurosci. 10, 573-584. doi:10.1038/nrn2682
79. Kaye, W., Strober, M., and Jimerson, D. (2008). "The neurobiology of eating disorders," in The Neurobiology of Mental Illness, 3rd Edn, eds D. Charney and E. Nestler (New York, NY: Oxford Press), 1349-1369.
80. Kaye, W., Strober, M., and Klump, K. L. (2003). "Neurobiology of eating disorders," in Pediatric Psychopharmacology, Principles & Practice, eds A. Martin, L. Scahill, D. S. Charney, and J. F. Leckman (New York, NY: Oxford University Press), 224-237.
81. Kaye, W., Wagner, A., Frank, G., and UF, B. (2006). "Review of brain imaging in anorexia and bulimia nervosa," inAED Annual Review of Eating Disorders, Part 2, eds J. Mitchell, S. Wonderlich, H. Steiger, and M. deZwaan (Abingdon: Radcliffe Publishing Ltd), 113-130.
82. Kaye, W., Wierenga, C., Bailer, U., Simmons, A., Wagner, A., and Bischoff-Grethe, A. (2013). Does a shared neurobiology for foods and drugs of abuse contribute to extremes of food ingestion in anorexia and bulimia nervosa? Biol. Psychiatry 73, 836-842. doi:10.1016/j.biopsych.2013.01.002
83. Kaye, W. H., Gwirtsman, H. E., George, D. T., Weiss, S. R., and Jimerson, D. C. (1986). Relationship of mood alterations to bingeing behaviour in bulimia. Br. J. Psychiatry 149, 479-485. doi:10.1192/bjp.149.4.479
84. Keel, P. K., Mitchell, J. E., Miller, K. B., Davis, T. L., and Crow, S. J. (1999). Long-term outcome of bulimia nervosa.Arch. Gen. Psychiatry 56, 63-69. doi:10.1001/archpsyc.56.1.63
85. Kendler, K. S., MacLean, C., Neale, M., Kessler, R., Heath, A., and Eaves, L. (1991). The genetic epidemiology of bulimia nervosa. Am. J. Psychiatry 148, 1627-1637.
86. Kim, H., Shimojo, S., and O'Doherty, J. (2011). Overlapping responses for the expectation of juice and money rewards in human ventromedial prefrontal cortex. Cereb. Cortex 21, 769-776. doi:10.1093/cercor/bhq145
87. Kim, K., Ku, J., Lee, J., Lee, H., and Jung, Y. (2012). Functional and effective connectivity of anterior insula in anorexia nervosa and bulimia nervosa. Neurosci. Lett. 521, 152-157. doi:10.1016/j.neulet.2012.05.075
88. Klein, D., and Walsh, B. (2003). Eating disorders. Int. Rev. Psychiatry 15, 205-216. doi:10.1080/0954026031000136839
89. Klump, K., Strober, M., Johnson, C., Thornton, L., Bulik, C., Devlin, B., et al. (2004). Personality characteristics of women before and after recovery from an eating disorder. Psychol. Med. 34, 1407-1418. doi:10.1017/S0033291704002442
90. Konishi, S., Nakajima, K., Uchida, I., Sekihara, K., and Miyashita, Y. (1998). No-go dominant brain activity in human inferior prefrontal cortex revealed by functional magnetic resonance imaging. Eur. J. Neurosci. 10, 1209-1213. doi:10.1046/j.1460-9568.1998.00167.x
91. Krug, I., Root, T., Bulik, C., Granero, R., Penelo, E., Jimenez-Murcia, S., et al. (2011). Redefining phenotypes in eating disorders based on personality: a latent profile analysis. Psychiatry Res. 188, 439-445. doi:10.1016/j.psychres.2011.05.026
92. Levy, D., Thavikulwat, A., and Glimcher, P. (2013). State dependent valuation: the effect of deprivation on risk preferences. PLoS ONE 8:e53978. doi:10.1371/journal.pone.0053978
93. Liao, P., Uher, R., Lawrence, N., Treasure, J., Schmidt, U., Campbell, I., et al. (2009). An examination of decision making in bulimia nervosa. J. Clin. Exp. Neuropsychol. 31, 455-461. doi:10.1080/13803390802251378
94. Lilenfeld, L. (2011). "Personality and temperament in eating disorders," in Current Topics in Behavioral Neurosciences, eds W. H. Kaye and R. Adan (New York, NY: Springer), 3-9.
95. Lilenfeld, L., Wonderlich, S., Riso, L. P., Crosby, R., and Mitchell, J. (2006). Eating disorders and personality: a methodological and empirical review. Clin. Psychol. Rev. 26, 299-320. doi:10.1016/j.cpr.2005.10.003
96. Lilenfeld, L. R., Kaye, W. H., Greeno, C. G., Merikangas, K. R., Plotnicov, K., Pollice, C., et al. (1998). A controlled family study of anorexia nervosa and bulimia nervosa: psychiatric disorders in first-degree relatives and effects of proband comorbidity. Arch. Gen. Psychiatry 55, 603-610. doi:10.1001/archpsyc.55.7.603
97. Lock, J., Garrett, A., Beenhakker, J., and Reiss, A. (2011). Aberrant brain activation during a response inhibition task in adolescent eating disorder subtypes. Am. J. Psychiatry 168, 55-64. doi:10.1176/appi.ajp.2010.10010056
98. Marsh, R., Horga, G., Wang, Z., Wang, P., Klahr, K., Berner, L., et al. (2011). An fMRI study of self-regulatory control and conflict resolution in adolescents with bulimia nervosa. Am. J. Psychiatry 168, 1210-1220. doi:10.1176/appi.ajp.2011.11010094
99. Marsh, R., Steinglass, J., Gerber, A., Graziano O'Leary, K., Wang, Z., Murphy, D., et al. (2009). Deficient activity in the neural systems that mediate self-regulatory control in bulimia nervosa. Arch. Gen. Psychiatry 66, 51-63. doi:10.1001/archgenpsychiatry.2008.504
100. Matton, A., Goossens, L., Braet, C., and Vervaet, M. (2013). Punishment and reward sensitivity: are naturally occurring clusters in these traits related to eating and weight problems in adolescents? Eur. Eat. Disord. Rev. 21, 184-194. doi:10.1002/erv.2226
101. McClure, S., Ericson, K., Laibson, D., Loewenstein, G., and Cohan, J. (2007). Time discounting for primary rewards.J. Neurosci. 27, 5796-5804. doi:10.1523/JNEUROSCI.4246-06.2007
102. McClure, S., Laibson, D., Loewenstein, G., and Cohen, J. (2004). Separate neural systems value immediate and delayed monetary rewards. Science 306, 503-507. doi:10.1126/science.1100907
103. McKenzie, J. M., and Joyce, P. R. (1992). Hospitalization for anorexia nervosa. Int. J. Eat. Disord. 11, 235-241. doi:10.1002/1098-108X(199204)11:3<235::AID-EAT2260110306>3.0.CO;2-T
104. Montague, R., Hyman, S., and Cohen, J. (2004). Computational roles for dopamine in behavioural control. Nature431, 760-767. doi:10.1038/nature03015
105. Nakazato, M., Hashimoto, K., Schmidt, U., Tchanturia, K., Campbell, I., Collier, D., et al. (2010). Serum glutamine, set-shifting ability and anorexia nervosa. Ann. Gen. Psychiatry 25, 29. doi:10.1186/1744-859X-9-29
106. Nakazato, M., Tchanturia, K., Schmidt, U., Campbell, I., Treasure, J., Collier, D., et al. (2009). Brain-derived neurotrophic factor (BDNF) and set-shifting in currently ill and recovered anorexia nervosa (AN) patients. Psychol. Med. 39, 1029-1035. doi:10.1017/S0033291708004108
107. Oberndorfer, T., Frank, G., Fudge, J., Simmons, A., Paulus, M., Wagner, A., et al. (2013a). Altered insula response to sweet taste processing after recovery from anorexia and bulimia nervosa. Am. J. Psychiatry 170, 1143-1151. doi:10.1176/appi.ajp.2013.11111745
108. Oberndorfer, T., Simmons, A., McCurdy, D., Strigo, I., Matthews, S., Yang, T., et al. (2013b). Greater anterior insula activation during anticipation of food images in women recovered from anorexia nervosa. Psychiatry Res. 214, 132-141. doi:10.1016/j.pscychresns.2013.06.010
109. Oberndorfer, T., Kaye, W., Simmons, A., Strigo, I., and Matthews, S. (2011). Demand-specific alteration of medial prefrontal cortex response during an inhibition task in recovered anorexic women. Int. J. Eat. Disord. 44, 1-8. doi:10.1002/eat.20750
110. Onoda, K., Okamoto, Y., Kunisato, Y., Aoyama, S., Shishida, K., Okada, G., et al. (2011). Inter-individual discount factor differences in reward prediction are topographically associated with caudate activation. Exp. Brain Res. 212, 593-601. doi:10.1007/s00221-011-2771-3
111. Paulus, M., and Stein, M. B. (2006). An insular view of anxiety. Biol. Psychiatry 60, 383-387. doi:10.1016/j.biopsych.2006.03.042
112. Paus, T., Collins, D., Evans, A., Leonard, G., Pike, B., and Zijdenbos, A. (2001). Maturation of white matter in the human brain: a review of magnetic resonance studies. Brain Res. Bull. 54, 255-266. doi:10.1016/S0361-9230(00)00434-2
113. Peñas-Lledó, E., Jiménez-Murcia, S., Granero, R., Penelo, E., Aguera, Z., Alvarez-Moya, E., et al. (2010). Specific eating disorder clusters based on social anxiety and novelty seeking. J. Anxiety Disord. 24, 767-773. doi:10.1016/j.janxdis.2010.05.010
114. Petersen, S., van Mier, H., Fiez, J., and Raichle, M. (1998). The effects of practice on the functional anatomy of task performance. Proc. Natl. Acad. Sci. U.S.A. 95, 853-860. doi:10.1073/pnas.95.3.853
115. Phillips, M., Drevets, W. R., Rauch, S. L., and Lane, R. (2003). Neurobiology of emotion perception I: the neural basis of normal emotion perception. Biol. Psychiatry 54, 504-514. doi:10.1016/S0006-3223(03)00168-9
116. Pieters, G., de Bruijn, E., Maas, Y., Hulstijn, W., Vandereycken, W., Pueskens, J., et al. (2007). Action monitoring and perfectionism in anorexia nervosa. Brain Cogn. 63, 42-50. doi:10.1016/j.bandc.2006.07.009
117. Pollice, C., Kaye, W. H., Greeno, C. G., and Weltzin, T. E. (1997). Relationship of depression, anxiety, and obsessionality to state of illness in anorexia nervosa. Int. J. Eat. Disord. 21, 367-376. doi:10.1002/(SICI)1098-108X(1997)21:4<367::AID-EAT10>3.0.CO;2-W
118. Radeloff, D., Willmann, K., Otto, L., Lindner, M., Putnam, K., van Leeuwen, S., et al. (2012). High-fat taste challenge reveals altered striatal response in women recovered from bulimia nervosa - a pilot study. World J. Biol. Psychiatry 15, 307-316. doi:10.3109/15622975.2012.671958
119. Roberts, M., Tchanturia, K., Stahl, D., Southgate, L., and Treasure, J. (2007). A systematic review and meta-analysis of set-shifting ability in eating disorders. Psychol. Med. 37, 1075-1084. doi:10.1017/S0033291707009877
120. Rosval, L., Steiger, H., Bruce, K., Israel, M., Richardson, J., and Aubut, M. (2006). Impulsivity in women with eating disorders: problem of response inhibition, planning, or attention? Int. J. Eat. Disord. 39, 590-593. doi:10.1002/eat.20296
121. Sato, Y., Saito, N., Utsumi, A., Aizawa, E., Shoji, T., Izumiyama, M., et al. (2013). Neural basis of impaired cognitive flexibility in patients with anorexia nervosa. PLoS ONE 8:e61108. doi:10.1371/journal.pone.0061108
122. Schienle, A., Schafer, A., Hermann, A., and Vaitl, D. (2009). Binge-eating disorder: reward sensitivity and brain activation to images of food. Biol. Psychiatry 65, 654-661. doi:10.1016/j.biopsych.2008.09.028
123. Schmidt, U., and Treasure, J. (2006). Anorexia nervosa: valued and visible. A cognitive-interpersonal maintenance model and its implications for research and practice. Br. J. Clin. Psychol. 45, 343-366. doi:10.1348/014466505X53902
124. Schultz, W. (2002). Getting formal with dopamine and reward. Neuron 36, 241-263. doi:10.1016/S0896-6273(02)00967-4
125. Schultz, W. (2004). Neural coding of basic reward terms of animal learning theory, game theory, microeconomics and behavioural ecology. Curr. Opin. Neurobiol. 14, 139-147. doi:10.1016/j.conb.2004.03.017
126. Simmons, A., Strigo, I., Matthews, S., Paulus, M., and Stein, M. (2006). Anticipation of aversive visual stimuli is associated with increased insula activation in anxiety-prone subjects. Biol. Psychiatry 60, 402-409. doi:10.1016/j.biopsych.2006.04.038
127. Sloan, D., Mizes, J., and Epstein, E. (2005). Empirical classification of eating disorders. Eat. Behav. 6, 53-62. doi:10.1016/j.eatbeh.2004.06.002
128. Small, D. (2009). Individual differences in the neurophysiology of reward and the obesity epidemic. Int. J. Obes.33(Suppl. 2), S44-S48. doi:10.1038/ijo.2009.71
129. Smyth, J., Wonderlich, S., Heron, K., Sliwinski, M., Crosby, R., Mitchell, J., et al. (2007). Daily and momentary mood and stress are associated with binge eating and vomiting in bulimia nervosa patients in the natural environment. J. Consult. Clin. Psychol. 75, 629-638. doi:10.1037/0022-006X.75.4.629
130. Sripada, C., Gonzalez, R., Phan, K., and Liberzon, I. (2011). The neural correlates of intertemporal decision-making: contributions of subjective value, stimulus type, and trait impulsivity. Hum. Brain Mapp. 32, 1637-1648. doi:10.1002/hbm.21136
131. Stedal, K., Frampton, I., Landro, N., and Lask, B. (2012). An examination of the Ravello profile - a neuropsychological test battery for anorexia nervosa. Eur. Eat. Disord. Rev. 20, 175-181. doi:10.1002/erv.1160
132. Steinglass, J., Albano, A., Simpson, H., Carpenter, K., Schebendach, J., and Attia, E. (2012). Fear of food as a treatment target: exposure and response prevention for anorexia nervosa in an open series. Int. J. Eat. Disord. 45, 615-621. doi:10.1002/eat.20936
133. Steinglass, J., Decker, H., Figner, B., and Walsh, B. (2014). Is Delay of Gratification a Stable Trait of Anorexia Nervosa? New York, NY: Society of Biological Psychiatry; New York Hilton Midtown.
134. Steinglass, J., Sysko, R., Mayer, L., Berner, L., Schebendach, J., Wang, Y., et al. (2010). Pre-meal anxiety and food intake in anorexia nervosa. Appetite 55, 214-218. doi:10.1016/j.appet.2010.05.090
135. Steinglass, J. E., Walsh, B. T., and Stern, Y. (2006). Set shifting deficit in anorexia nervosa. J. Int. Neuropsychol. Soc. 12, 431-435. doi:10.1017/S1355617706060528
136. Stice, E., Spoor, S., Bohon, C., and Small, D. (2008). Relation between obesity and blunted striatal response to foods is moderated by TaqIA A1 allele. Science 322, 449-452. doi:10.1126/science.1161550
137. Stice, E., Spoor, S., Ng, J., and Zald, D. (2009). Relation of obesity to consummatory and anticipatory food reward.Physiol. Behav. 97, 551-560. doi:10.1016/j.physbeh.2009.03.020
138. Stice, E., Yokum, S., Burger, K., Epstein, L., and Small, D. (2011). Youth at risk for obesity show greater activation of striatal and somatosensory regions to food. J. Neurosci. 31, 4360-4366. doi:10.1523/JNEUROSCI.6604-10.2011
139. Strober, M., Freeman, R., Lampert, C., Diamond, J., and Kaye, W. (2000). Controlled family study of anorexia nervosa and bulimia nervosa: evidence of shared liability and transmission of partial syndromes. Am. J. Psychiatry157, 393-401. doi:10.1176/appi.ajp.157.3.393
140. Strober, M., Freeman, R., and Morrell, W. (1997). The long-term course of severe anorexia nervosa in adolescents: survival analysis of recovery, relapse, and outcome predictors over 10-15 years in a prospective study. Int. J. Eat. Disord. 22, 339-360. doi:10.1002/(SICI)1098-108X(199712)22:4<339::AID-EAT1>3.0.CO;2-N
141. Sullivan, P. F. (1995). Mortality in anorexia nervosa. Am. J. Psychiatry 152, 1073-1074.
142. Suskauer, S., Simmonds, D., Caffo, B., Denckla, M., Pekar, J., and Mostofsky, S. (2008). fMRI of intrasubject variability in ADHD: anomalous premotor activity with prefrontal compensation. J. Am. Acad. Child Adolesc. Psychiatry 47, 1141-1150. doi:10.1097/CHI.0b013e3181825b1f
143. Tal, A., and Wansink, B. (2013). Fattening fasting: hungry grocery shoppers buy more calories, not more food.JAMA Intern. Med. 173, 1146-1148. doi:10.1001/jamainternmed.2013.650
144. Tchanturia, K., Davies, H., Roberts, M., Harrison, A., Nakazato, M., Schmidt, U., et al. (2012). Poor cognitive flexibility in eating disorders: examining the evidence using the wisconsin card sorting task. PLoS ONE 7:e28331. doi:10.1371/journal.pone.0028331
145. Tchanturia, K., Morris, R., Surguladze, S., and Treasure, J. (2002). An examination of perceptual and cognitive set shifting tasks in acute anorexia nervosa and following recovery. Eat. Weight Disord. 7, 312-315. doi:10.1007/BF03324978
146. Thompson-Brenner, H., Eddy, K., Franko, D., Dorer, D., Vaschenko, M., Kass, A., et al. (2008). A personality classification system for eating disorders: a longitudinal study. Compr. Psychiatry 49, 551-560. doi:10.1016/j.comppsych.2008.04.002
147. Torrubia, R., Avila, C., Molto, J., and Caseras, X. (2001). The sensitivity to punishment and sensitivity to reward questionnaire (SPSRQ) as a measure of Gray's anxiety and impulsivity dimensions. Pers. Individ. Dif. 31, 837-862. doi:10.1016/j.paid.2006.04.024
148. Uher, R., Brammer, M., Murphy, T., Campbell, I., Ng, V., Williams, S., et al. (2003). Recovery and chronicity in anorexia nervosa: brain activity associated with differential outcomes. Biol. Psychiatry 54, 934-942. doi:10.1016/S0006-3223(03)00172-0
149. van den Heuvel, O., Veltman, D., Groenewegen, H., Witter, M., Merkelbach, J., Cath, D., et al. (2005). Disorder-specific neuroanatomical correlates of attentional bias in obsessive-compulsive disorder, panic disorder, and hypochondriasis. Arch. Gen. Psychiatry 62, 922-933. doi:10.1001/archpsyc.62.8.922
150. Velázquez-Sánchez, C., Ferragud, A., Moore, C., Everitt, B., Sabino, V., and Cottone, P. (2014). High trait impulsivity predicts food addiction-like behavior in the rat. Neuropsychopharmacology 39, 2643-2672. doi:10.1038/npp.2014.98
151. Vitousek, K., and Manke, F. (1994). Personality variables and disorders in anorexia nervosa and bulimia nervosa. J. Abnorm. Psychol. 103, 137-147. doi:10.1037/0021-843X.103.1.137
152. Vocks, S., Herpertz, S., Rosenberger, C., Senf, W., and Gizewski, E. (2011). Effects of gustatory stimulation on brain activity during hunger and satiety in females with restricting-type anorexia nervosa: an fMRI study. J. Psychiatr. Res. 45, 395-403. doi:10.1016/j.jpsychires.2010.07.012
153. Vogt, B., Vogt, L., Farber, N., and Bush, G. (2005). Architecture and neurocytology of monkey cingulate gyrus. J. Comp. Neurol. 485, 218-239. doi:10.1002/cne.20512
154. Volkow, N., Wang, G., Fowler, J., Tomasi, A., and Baler, R. (2012). Food and drug reward: overlapping circuits in human obesity and addiction. Curr. Top. Behav. Neurosci. 11, 1-24. doi:10.1007/7854_2011_169
155. Wagner, A., Aizeinstein, H., Venkatraman, V., Bischoff-Grethe, A., Fudge, J., May, J., et al. (2010). Altered striatal response to reward in bulimia nervosa after recovery. Int. J. Eat. Disord. 43, 289-294. doi:10.1002/eat.20699
156. Wagner, A., Aizenstein, H., Frank, G. K., Figurski, J., May, J. C., Putnam, K., et al. (2008). Altered insula response to a taste stimulus in individuals recovered from restricting-type anorexia nervosa. Neuropsychopharmacology 33, 513-523. doi:10.1038/sj.npp.1301443
157. Wagner, A., Aizenstein, H., Venkatraman, M., Fudge, J., May, J., Mazurkewicz, L., et al. (2007). Altered reward processing in women recovered from anorexia nervosa. Am. J. Psychiatry 164, 1842-1849. doi:10.1176/appi.ajp.2007.07040575
158. Wagner, A., Barbarich, N., Frank, G., Bailer, U., Weissfeld, L., Henry, S., et al. (2006). Personality traits after recovery from eating disorders: do subtypes differ? Int. J. Eat. Disord. 39, 276-284. doi:10.1002/eat.20251
159. Walters, E. E., and Kendler, K. S. (1995). Anorexia nervosa and anorexic-like syndromes in a population-based female twin sample. Am. J. Psychiatry 152, 64-71.
160. Walton, M., Bannerman, D., Alterescu, K., and Rushworth, M. (2003). Functional specialization within medial frontal cortex of the anterior cingulate for evaluating effort-related decisions. J. Neurosci. 23, 6475-6479.
161. Wang, X., and Dvorak, R. (2010). Sweet future: fluctuating blood glucose levels affect future discounting. Psychol. Sci. 21, 183-188. doi:10.1177/0956797609358096
162. Wartenburger, I., Heekeren, H., Preusse, F., Kramer, J., and van der Meer, E. (2009). Cerebral correlates of analogical processing and their modulation by training. Neuroimage 48, 291-302. doi:10.1016/j.neuroimage.2009.06.025
163. Westen, D., and Harnden-Fischer, J. (2001). Personality profiles in eating disorders: rethinking the distinction between axis I and axis II. Am. J. Psychiatry 158, 547-562. doi:10.1176/appi.ajp.158.4.547
164. Weygandt, M., Schaefer, A., Schienle, A., and Haynes, J. (2012). Diagnosing different binge-eating disorders based on reward-related brain activation patterns. Hum. Brain Mapp. 33, 2135-2146. doi:10.1002/hbm.21345
165. Wierenga, C., Bischoff-Grethe, A., Melrose, A., Torres, L., Irvine, L., and Bailer, U. F. (2014a). Hunger does not motivate reward in women remitted from anorexia nervosa. Biol. Psychiatry (in press). doi:10.1016/j.biopsych.2014.09.024
166. Wierenga, C., Bischoff-Grethe, A., Melrose, J., Grenesko-Stevens, E., Irvine, Z., Wagner, A., et al. (2014b). Altered BOLD response during inhibitory and error processing in adolescents with anorexia nervosa. PLoS ONE 9:e92017. doi:10.1371/journal.pone.0092017
167. Wittman, M. L., Lovero, K. L., Lane, S. D., and Paulus, M. P. (2010). Now or later? Striatum and insula activation to immediate versus delayed rewards. J. Neurosci. Psychol. Econ. 3, 15-26. doi:10.1037/a0017252
168. Wittmann, M., Leland, D., and Paulus, M. (2007). Time and decision making: differential contribution of the posterior insular cortex and the striatum during a delay discounting task. Exp. Brain Res. 179, 643-653. doi:10.1007/s00221-006-0822-y
169. Wonderlich, S., Crosby, R., Joiner, T., Peterson, C., Bardone-Cone, A., Klein, M., et al. (2005). Personality subtyping and bulimia nervosa: psychopathological and genetic correlates. Psychol. Med. 35, 649-657. doi:10.1017/S0033291704004234
170. Wu, M., Hartmann, M., Skunde, M., Herzog, W., and Friederich, H. (2013). Inhibitory control in bulimic-type eating disorders: a systematic review and meta-analysis. PLoS ONE 8:e83412. doi:10.1371/journal.pone.0083412
171. Yin, H., and Knowlton, B. (2006). The role of the basal ganglia in habit formation. Nat. Rev. Neurosci. 7, 464-476. doi:10.1038/nrn1919
172. Zastrow, A., Kaiser, S. S., Stippich, C., Walther, S., Herzog, W., Tchanturia, K., et al. (2009). Neural correlates of impaired cognitive-behavioral flexibility in anorexia nervosa. Am. J. Psychiatry 166, 608-616. doi:10.1176/appi.ajp.2008.08050775