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Volumn 154, Issue 2, 2014, Pages 141-154

Should IFN-γ, IL-17 and IL-2 be considered predictive biomarkers of acute rejection in liver and kidney transplant? Results of a multicentric study

Author keywords

Acute rejection; ; Bootstrap; IFN , IL 2 and IL 17; ; Kidney transplantation; ; Liver transplantation;

Indexed keywords

AMINOTRANSFERASE; BASILIXIMAB; CD4 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2; MYCOPHENOLIC ACID; PREDNISONE; TACROLIMUS; THYMOCYTE ANTIBODY;

EID: 84905867612     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2014.07.007     Document Type: Article
Times cited : (61)

References (45)
  • 1
    • 79960630579 scopus 로고    scopus 로고
    • Biomarkers in solid organ transplantation: establishing personalized transplantation medicine
    • Roedder S., Vitalone M., Khatri P., Sarwal M.M. Biomarkers in solid organ transplantation: establishing personalized transplantation medicine. Genome Med. 2011, 3(6):37.
    • (2011) Genome Med. , vol.3 , Issue.6 , pp. 37
    • Roedder, S.1    Vitalone, M.2    Khatri, P.3    Sarwal, M.M.4
  • 2
    • 77957556484 scopus 로고    scopus 로고
    • A 'biomarker signature' for tolerance in transplantation
    • Hernandez-Fuentes M.P., Lechler R.I. A 'biomarker signature' for tolerance in transplantation. Nat. Rev. Nephrol. 2010, 6(10):606-613.
    • (2010) Nat. Rev. Nephrol. , vol.6 , Issue.10 , pp. 606-613
    • Hernandez-Fuentes, M.P.1    Lechler, R.I.2
  • 3
    • 79959667859 scopus 로고    scopus 로고
    • Peripheral blood sampling for the detection of allograft rejection: biomarker identification and validation
    • Heidt S., San Segundo D., Shankar S., Mittal S., Muthusamy A.S., Friend P.J., et al. Peripheral blood sampling for the detection of allograft rejection: biomarker identification and validation. Transplantation 2011, 92(1):1-9.
    • (2011) Transplantation , vol.92 , Issue.1 , pp. 1-9
    • Heidt, S.1    San Segundo, D.2    Shankar, S.3    Mittal, S.4    Muthusamy, A.S.5    Friend, P.J.6
  • 4
    • 16244368059 scopus 로고    scopus 로고
    • + T cells and interferon-gamma to the progress of chronic rejection of kidney allografts: the Th1 response mediates both acute and chronic rejection
    • + T cells and interferon-gamma to the progress of chronic rejection of kidney allografts: the Th1 response mediates both acute and chronic rejection. Transpl. Immunol. 2005, 14(1):21-25.
    • (2005) Transpl. Immunol. , vol.14 , Issue.1 , pp. 21-25
    • Obata, F.1    Yoshida, K.2    Ohkubo, M.3    Ikeda, Y.4    Taoka, Y.5    Takeuchi, Y.6
  • 5
    • 84872154468 scopus 로고    scopus 로고
    • Increase of peripheral Th17 lymphocytes during acute cellular rejection in liver transplant recipients
    • Fan H., Li L.X., Han D.D., Kou J.T., Li P., He Q. Increase of peripheral Th17 lymphocytes during acute cellular rejection in liver transplant recipients. Hepatobiliary Pancreat. Dis. Int. 2012, 11(6):606-611.
    • (2012) Hepatobiliary Pancreat. Dis. Int. , vol.11 , Issue.6 , pp. 606-611
    • Fan, H.1    Li, L.X.2    Han, D.D.3    Kou, J.T.4    Li, P.5    He, Q.6
  • 6
    • 33847206969 scopus 로고    scopus 로고
    • IL-17 family cytokines and the expanding diversity of effector T cell lineages
    • Weaver C.T., Hatton R.D., Mangan P.R., Harrington L.E. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 2007, 25:821-852.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 821-852
    • Weaver, C.T.1    Hatton, R.D.2    Mangan, P.R.3    Harrington, L.E.4
  • 7
    • 33748925713 scopus 로고    scopus 로고
    • After TH1/TH2 now comes Treg/TH17: significance of T helper cells in immune response organization
    • Homey B. After TH1/TH2 now comes Treg/TH17: significance of T helper cells in immune response organization. Hautarzt 2006, 57(8):730-732.
    • (2006) Hautarzt , vol.57 , Issue.8 , pp. 730-732
    • Homey, B.1
  • 8
    • 47749124186 scopus 로고    scopus 로고
    • Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammat
    • Ichiyama K., Yoshida H., Wakabayashi Y., Chinen T., Saeki K., Nakaya M., et al. Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammat. J. Biol. Chem. 2008, 283(25):17003-17008.
    • (2008) J. Biol. Chem. , vol.283 , Issue.25 , pp. 17003-17008
    • Ichiyama, K.1    Yoshida, H.2    Wakabayashi, Y.3    Chinen, T.4    Saeki, K.5    Nakaya, M.6
  • 9
    • 0037093372 scopus 로고    scopus 로고
    • Multiple pathways to allograft rejection
    • Le Moine A., Goldman M., Abramowicz D. Multiple pathways to allograft rejection. Transplantation 2002, 73(9):1373-1381.
    • (2002) Transplantation , vol.73 , Issue.9 , pp. 1373-1381
    • Le Moine, A.1    Goldman, M.2    Abramowicz, D.3
  • 10
    • 77953347252 scopus 로고    scopus 로고
    • Pretransplant urine cytokine pattern predicts acute kidney rejection
    • Karczewski J., Karczewski M., Wiktorowicz K. Pretransplant urine cytokine pattern predicts acute kidney rejection. Cytokine 2010, 51(1):10-11.
    • (2010) Cytokine , vol.51 , Issue.1 , pp. 10-11
    • Karczewski, J.1    Karczewski, M.2    Wiktorowicz, K.3
  • 11
    • 67649210785 scopus 로고    scopus 로고
    • Relative roles of Th1 and Th17 effector cells in allograft rejection
    • Atalar K., Afzali B., Lord G., Lombardi G. Relative roles of Th1 and Th17 effector cells in allograft rejection. Curr. Opin. Organ Transplant. 2009, 14(1):23-29.
    • (2009) Curr. Opin. Organ Transplant. , vol.14 , Issue.1 , pp. 23-29
    • Atalar, K.1    Afzali, B.2    Lord, G.3    Lombardi, G.4
  • 12
    • 3042651960 scopus 로고    scopus 로고
    • Defective inhibition of peripheral CD8+ T cell IL-2 production by anti-calcineurin drugs during acute liver allograft rejection
    • Boleslawski E., Conti F., Sanquer S., Podevin P., Chouzenoux S., Batteux F., et al. Defective inhibition of peripheral CD8+ T cell IL-2 production by anti-calcineurin drugs during acute liver allograft rejection. Transplantation 2004, 77(12):1815-1820.
    • (2004) Transplantation , vol.77 , Issue.12 , pp. 1815-1820
    • Boleslawski, E.1    Conti, F.2    Sanquer, S.3    Podevin, P.4    Chouzenoux, S.5    Batteux, F.6
  • 13
    • 78149284732 scopus 로고    scopus 로고
    • Biomarkers of immunoregulatory status in stable liver transplant recipients undergoing weaning of immunosuppressive therapy
    • Millan O., Benitez C., Guillen D., Lopez A., Rimola A., Sanchez-Fueyo A., et al. Biomarkers of immunoregulatory status in stable liver transplant recipients undergoing weaning of immunosuppressive therapy. Clin. Immunol. 2010, 137(3):337-346.
    • (2010) Clin. Immunol. , vol.137 , Issue.3 , pp. 337-346
    • Millan, O.1    Benitez, C.2    Guillen, D.3    Lopez, A.4    Rimola, A.5    Sanchez-Fueyo, A.6
  • 14
    • 84873150010 scopus 로고    scopus 로고
    • Intracellular IFN-gamma and IL-2 expression monitoring as surrogate markers of the risk of acute rejection and personal drug response in de novo liver transplant recipients
    • Millan O., Rafael-Valdivia L., Torrademe E., Lopez A., Fortuna V., Sanchez-Cabus S., et al. Intracellular IFN-gamma and IL-2 expression monitoring as surrogate markers of the risk of acute rejection and personal drug response in de novo liver transplant recipients. Cytokine 2013, 61(2):556-564.
    • (2013) Cytokine , vol.61 , Issue.2 , pp. 556-564
    • Millan, O.1    Rafael-Valdivia, L.2    Torrademe, E.3    Lopez, A.4    Fortuna, V.5    Sanchez-Cabus, S.6
  • 15
    • 10644278692 scopus 로고    scopus 로고
    • Enzyme-linked immunosorbent spot assay for donor-reactive interferon-gamma-producing cells identifies T-cell presensitization and correlates with graft function at 6 and 12months in renal-transplant recipients
    • Nickel P., Presber F., Bold G., Biti D., Schonemann C., Tullius S.G., et al. Enzyme-linked immunosorbent spot assay for donor-reactive interferon-gamma-producing cells identifies T-cell presensitization and correlates with graft function at 6 and 12months in renal-transplant recipients. Transplantation 2004, 78(11):1640-1646.
    • (2004) Transplantation , vol.78 , Issue.11 , pp. 1640-1646
    • Nickel, P.1    Presber, F.2    Bold, G.3    Biti, D.4    Schonemann, C.5    Tullius, S.G.6
  • 16
    • 37049010274 scopus 로고    scopus 로고
    • Pretransplant donor-specific interferon-gamma ELISPOT assay predicts acute rejection episodes in renal transplant recipients
    • Kim S.H., Oh E.J., Kim M.J., Park Y.J., Han K., Yang H.J., et al. Pretransplant donor-specific interferon-gamma ELISPOT assay predicts acute rejection episodes in renal transplant recipients. Transplant. Proc. 2007, 39(10):3057-3060.
    • (2007) Transplant. Proc. , vol.39 , Issue.10 , pp. 3057-3060
    • Kim, S.H.1    Oh, E.J.2    Kim, M.J.3    Park, Y.J.4    Han, K.5    Yang, H.J.6
  • 17
    • 48149108073 scopus 로고    scopus 로고
    • Circulating alloreactive T cells correlate with graft function in longstanding renal transplant recipients
    • Bestard O., Nickel P., Cruzado J.M., Schoenemann C., Boenisch O., Sefrin A., et al. Circulating alloreactive T cells correlate with graft function in longstanding renal transplant recipients. J. Am. Soc. Nephrol. 2008, 19(7):1419-1429.
    • (2008) J. Am. Soc. Nephrol. , vol.19 , Issue.7 , pp. 1419-1429
    • Bestard, O.1    Nickel, P.2    Cruzado, J.M.3    Schoenemann, C.4    Boenisch, O.5    Sefrin, A.6
  • 18
    • 0032939561 scopus 로고    scopus 로고
    • Evidence for a role of IL-17 in organ allograft rejection: IL-17 promotes the functional differentiation of dendritic cell progenitors
    • Antonysamy M.A., Fanslow W.C., Fu F., Li W., Qian S., Troutt A.B., et al. Evidence for a role of IL-17 in organ allograft rejection: IL-17 promotes the functional differentiation of dendritic cell progenitors. J. Immunol. 1999, 162(1):577-584.
    • (1999) J. Immunol. , vol.162 , Issue.1 , pp. 577-584
    • Antonysamy, M.A.1    Fanslow, W.C.2    Fu, F.3    Li, W.4    Qian, S.5    Troutt, A.B.6
  • 20
    • 0034765223 scopus 로고    scopus 로고
    • IL-17 expression as a possible predictive parameter for subclinical renal allograft rejection
    • Hsieh H.G., Loong C.C., Lui W.Y., Chen A., Lin C.Y. IL-17 expression as a possible predictive parameter for subclinical renal allograft rejection. Transpl. Int. 2001, 14(5):287-298.
    • (2001) Transpl. Int. , vol.14 , Issue.5 , pp. 287-298
    • Hsieh, H.G.1    Loong, C.C.2    Lui, W.Y.3    Chen, A.4    Lin, C.Y.5
  • 21
    • 68349144297 scopus 로고    scopus 로고
    • Changes in the serum levels of interleukin-17/interleukin-23 during acute rejection in liver transplantation
    • Fabrega E., Lopez-Hoyos M., San Segundo D., Casafont F., Pons-Romero F. Changes in the serum levels of interleukin-17/interleukin-23 during acute rejection in liver transplantation. Liver Transpl. 2009, 15(6):629-633.
    • (2009) Liver Transpl. , vol.15 , Issue.6 , pp. 629-633
    • Fabrega, E.1    Lopez-Hoyos, M.2    San Segundo, D.3    Casafont, F.4    Pons-Romero, F.5
  • 22
    • 79958856466 scopus 로고    scopus 로고
    • IL-17 expression by tubular epithelial cells in renal transplant recipients with acute antibody-mediated rejection
    • Loverre A., Tataranni T., Castellano G., Divella C., Battaglia M., Ditonno P., et al. IL-17 expression by tubular epithelial cells in renal transplant recipients with acute antibody-mediated rejection. Am. J. Transplant. 2011, 11(6):1248-1259.
    • (2011) Am. J. Transplant. , vol.11 , Issue.6 , pp. 1248-1259
    • Loverre, A.1    Tataranni, T.2    Castellano, G.3    Divella, C.4    Battaglia, M.5    Ditonno, P.6
  • 24
    • 0031052357 scopus 로고    scopus 로고
    • Banff schema for grading liver allograft rejection: an international consensus document
    • Banff schema for grading liver allograft rejection: an international consensus document. Hepatology 1997, 25(3):658-663.
    • (1997) Hepatology , vol.25 , Issue.3 , pp. 658-663
  • 25
    • 33644616547 scopus 로고    scopus 로고
    • Sequential determination of pharmacokinetics and pharmacodynamics of mycophenolic acid in liver transplant patients treated with mycophenolate mofetil
    • Brunet M., Cirera I., Martorell J., Vidal E., Millan O., Jimenez O., et al. Sequential determination of pharmacokinetics and pharmacodynamics of mycophenolic acid in liver transplant patients treated with mycophenolate mofetil. Transplantation 2006, 81(4):541-546.
    • (2006) Transplantation , vol.81 , Issue.4 , pp. 541-546
    • Brunet, M.1    Cirera, I.2    Martorell, J.3    Vidal, E.4    Millan, O.5    Jimenez, O.6
  • 26
    • 67651115805 scopus 로고    scopus 로고
    • The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: the Symphony pharmacokinetic substudy
    • Grinyo J.M., Ekberg H., Mamelok R.D., Oppenheimer F., Sanchez-Plumed J., Gentil M.A., et al. The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: the Symphony pharmacokinetic substudy. Nephrol. Dial. Transplant. 2009, 24(7):2269-2276.
    • (2009) Nephrol. Dial. Transplant. , vol.24 , Issue.7 , pp. 2269-2276
    • Grinyo, J.M.1    Ekberg, H.2    Mamelok, R.D.3    Oppenheimer, F.4    Sanchez-Plumed, J.5    Gentil, M.A.6
  • 27
    • 0034699514 scopus 로고    scopus 로고
    • Flow cytometric measurement of intracellular cytokines
    • Pala P., Hussell T., Openshaw P.J. Flow cytometric measurement of intracellular cytokines. J. Immunol. Methods 2000, 243(1-2):107-124.
    • (2000) J. Immunol. Methods , vol.243 , Issue.1-2 , pp. 107-124
    • Pala, P.1    Hussell, T.2    Openshaw, P.J.3
  • 28
    • 4444318682 scopus 로고    scopus 로고
    • Optimum culture conditions for specific and nonspecific activation of whole blood and PBMC for intracellular cytokine assessment by flow cytometry
    • Godoy-Ramirez K., Franck K., Mahdavifar S., Andersson L., Gaines H. Optimum culture conditions for specific and nonspecific activation of whole blood and PBMC for intracellular cytokine assessment by flow cytometry. J. Immunol. Methods 2004, 292(1-2):1-15.
    • (2004) J. Immunol. Methods , vol.292 , Issue.1-2 , pp. 1-15
    • Godoy-Ramirez, K.1    Franck, K.2    Mahdavifar, S.3    Andersson, L.4    Gaines, H.5
  • 29
    • 16244366026 scopus 로고
    • Index for ratting diagnosis test
    • Youden W. Index for ratting diagnosis test. Cancer Biol. Ther. 1950, 3:32-35.
    • (1950) Cancer Biol. Ther. , vol.3 , pp. 32-35
    • Youden, W.1
  • 30
    • 0020083498 scopus 로고
    • The meaning and use of the area under a receiver operating characteristic (ROC) curve
    • Hanley J.A., McNeil B.J. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 1982, 143(1):29-36.
    • (1982) Radiology , vol.143 , Issue.1 , pp. 29-36
    • Hanley, J.A.1    McNeil, B.J.2
  • 31
    • 0002704161 scopus 로고    scopus 로고
    • Model-building strategies and methods for logistic regression
    • Wiley, New York, D. Hosmer, S. Lemeshow (Eds.)
    • Hosmer D., Lemeshow S. Model-building strategies and methods for logistic regression. Applied Logistic Regression 2000, 91-142. Wiley, New York. 2nd ed. D. Hosmer, S. Lemeshow (Eds.).
    • (2000) Applied Logistic Regression , pp. 91-142
    • Hosmer, D.1    Lemeshow, S.2
  • 32
    • 0024592074 scopus 로고
    • The impact of confounder selection criteria on effect estimation
    • Mickey R.M., Greenland S. The impact of confounder selection criteria on effect estimation. Am. J. Epidemiol. 1989, 129(1):125-137.
    • (1989) Am. J. Epidemiol. , vol.129 , Issue.1 , pp. 125-137
    • Mickey, R.M.1    Greenland, S.2
  • 33
    • 77950991213 scopus 로고    scopus 로고
    • Model development
    • Chapman & Hall/CRC Press, Boca Raton, J. Hilbe (Ed.)
    • Hilbe J. Model development. Logistic Regression Models 2009, 73-187. Chapman & Hall/CRC Press, Boca Raton. J. Hilbe (Ed.).
    • (2009) Logistic Regression Models , pp. 73-187
    • Hilbe, J.1
  • 35
    • 0030069896 scopus 로고    scopus 로고
    • Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors
    • Harrel F.E., Lee K.L., Mark D.B. Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors. Stat. Med. 1996, 15:361-387.
    • (1996) Stat. Med. , vol.15 , pp. 361-387
    • Harrel, F.E.1    Lee, K.L.2    Mark, D.B.3
  • 36
    • 0034068707 scopus 로고    scopus 로고
    • Cytokine profile of liver- and blood-derived nonspecific T cells after liver transplantation: T helper cells type 1/0 lymphokines dominate in recurrent hepatitis C virus infection and rejection
    • Schirren C.A., Jung M., Worzfeld T., Mamin M., Baretton G.B., Gruener N.H., et al. Cytokine profile of liver- and blood-derived nonspecific T cells after liver transplantation: T helper cells type 1/0 lymphokines dominate in recurrent hepatitis C virus infection and rejection. Liver Transpl. 2000, 6(2):222-228.
    • (2000) Liver Transpl. , vol.6 , Issue.2 , pp. 222-228
    • Schirren, C.A.1    Jung, M.2    Worzfeld, T.3    Mamin, M.4    Baretton, G.B.5    Gruener, N.H.6
  • 37
    • 70349918127 scopus 로고    scopus 로고
    • Interleukin-2 in CD8+ T cells correlates with Banff score during organ rejection in liver transplant recipients
    • Akoglu B., Kriener S., Martens S., Herrmann E., Hofmann W.P., Milovic V., et al. Interleukin-2 in CD8+ T cells correlates with Banff score during organ rejection in liver transplant recipients. Clin. Exp. Med. 2009, 9(4):259-262.
    • (2009) Clin. Exp. Med. , vol.9 , Issue.4 , pp. 259-262
    • Akoglu, B.1    Kriener, S.2    Martens, S.3    Herrmann, E.4    Hofmann, W.P.5    Milovic, V.6
  • 38
    • 84863275042 scopus 로고    scopus 로고
    • Intracellular interferon-gamma staining analysis of donor-specific T-cell responses in liver transplant recipients
    • Okanami Y., Tsujimura K., Mizuno S., Tabata M., Isaji S., Akatsuka Y., et al. Intracellular interferon-gamma staining analysis of donor-specific T-cell responses in liver transplant recipients. Transplant. Proc. 2012, 44(2):548-554.
    • (2012) Transplant. Proc. , vol.44 , Issue.2 , pp. 548-554
    • Okanami, Y.1    Tsujimura, K.2    Mizuno, S.3    Tabata, M.4    Isaji, S.5    Akatsuka, Y.6
  • 39
    • 84865714930 scopus 로고    scopus 로고
    • Pretransplant IFN-gamma ELISPOT assay as a potential screening test to select immunosuppression protocols for patients receiving basiliximab induction therapy
    • Kim Y., Park K.H., Chung B.H., Choi B.S., Yang C.W., Kim J.I., et al. Pretransplant IFN-gamma ELISPOT assay as a potential screening test to select immunosuppression protocols for patients receiving basiliximab induction therapy. Transl. Res. 2012, 160(3):230-236.
    • (2012) Transl. Res. , vol.160 , Issue.3 , pp. 230-236
    • Kim, Y.1    Park, K.H.2    Chung, B.H.3    Choi, B.S.4    Yang, C.W.5    Kim, J.I.6
  • 40
    • 84870544713 scopus 로고    scopus 로고
    • Distinct expression of interleukin 17, tumor necrosis factor alpha, transforming growth factor beta, and forkhead box P3 in acute rejection after kidney transplantation
    • de Menezes Neves P.D., Machado J.R., dos Reis M.A., Faleiros A.C., de Lima Pereira S.A., Rodrigues D.B. Distinct expression of interleukin 17, tumor necrosis factor alpha, transforming growth factor beta, and forkhead box P3 in acute rejection after kidney transplantation. Ann. Diagn. Pathol. 2013, 17(1):75-79.
    • (2013) Ann. Diagn. Pathol. , vol.17 , Issue.1 , pp. 75-79
    • de Menezes Neves, P.D.1    Machado, J.R.2    dos Reis, M.A.3    Faleiros, A.C.4    de Lima Pereira, S.A.5    Rodrigues, D.B.6
  • 42
    • 27544465354 scopus 로고    scopus 로고
    • A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
    • Park H., Li Z., Yang X.O., Chang S.H., Nurieva R., Wang Y.H., et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 2005, 6(11):1133-1141.
    • (2005) Nat. Immunol. , vol.6 , Issue.11 , pp. 1133-1141
    • Park, H.1    Li, Z.2    Yang, X.O.3    Chang, S.H.4    Nurieva, R.5    Wang, Y.H.6
  • 43
    • 36248975343 scopus 로고    scopus 로고
    • Interleukin-23 and TH17 cells in transplantation immunity: does 23+17 equal rejection?
    • Chen Y., Wood K.J. Interleukin-23 and TH17 cells in transplantation immunity: does 23+17 equal rejection?. Transplantation 2007, 84(9):1071-1074.
    • (2007) Transplantation , vol.84 , Issue.9 , pp. 1071-1074
    • Chen, Y.1    Wood, K.J.2
  • 44
    • 84873145622 scopus 로고    scopus 로고
    • Long-term heart transplant survival by targeting the ionotropic purinergic receptor P2X7
    • Vergani A., Tezza S., D'Addio F., Fotino C., Liu K., Niewczas M., et al. Long-term heart transplant survival by targeting the ionotropic purinergic receptor P2X7. Circulation 2013, 127:463-475.
    • (2013) Circulation , vol.127 , pp. 463-475
    • Vergani, A.1    Tezza, S.2    D'Addio, F.3    Fotino, C.4    Liu, K.5    Niewczas, M.6
  • 45
    • 0034906866 scopus 로고    scopus 로고
    • Internal validation of predictive models: efficiency of some procedures for logistic regression analysis
    • Steyerberg E.W., Harrell F.E., Borsboom G.J., et al. Internal validation of predictive models: efficiency of some procedures for logistic regression analysis. J. Clin. Epidemiol. 2001, 54:774-781.
    • (2001) J. Clin. Epidemiol. , vol.54 , pp. 774-781
    • Steyerberg, E.W.1    Harrell, F.E.2    Borsboom, G.J.3


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