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Volumn 61, Issue 2, 2013, Pages 556-564

Intracellular IFN-γ and IL-2 expression monitoring as surrogate markers of the risk of acute rejection and personal drug response in de novo liver transplant recipients

Author keywords

Acute rejection; IFN and IL 2; Liver transplantation; Personal drug response; Surrogate marker

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS;

EID: 84873150010     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2012.10.026     Document Type: Article
Times cited : (65)

References (24)
  • 1
    • 34249915322 scopus 로고    scopus 로고
    • The liver: a special case in transplant tolerance
    • Benseler V., McCaughan G.W., Schlitt H.J., et al. The liver: a special case in transplant tolerance. Semin Liver Dis 2007, 27:94-213.
    • (2007) Semin Liver Dis , vol.27 , pp. 94-213
    • Benseler, V.1    McCaughan, G.W.2    Schlitt, H.J.3
  • 2
    • 0016683869 scopus 로고
    • Identity and cytotoxic capacity of cells infiltrating renal allografts
    • Strom T.B., Tilney N.L., Carpenter C.B., et al. Identity and cytotoxic capacity of cells infiltrating renal allografts. N Engl J Med 1975, 292:1257-1263.
    • (1975) N Engl J Med , vol.292 , pp. 1257-1263
    • Strom, T.B.1    Tilney, N.L.2    Carpenter, C.B.3
  • 3
    • 56649102220 scopus 로고    scopus 로고
    • Novel noninvasive assays to predict transplantation rejection and tolerance. enumeration of cytokine-producing alloreactive T cells
    • Benítez F., Najafian N. Novel noninvasive assays to predict transplantation rejection and tolerance. enumeration of cytokine-producing alloreactive T cells. Clin Lab Med 2008, 28:365-373.
    • (2008) Clin Lab Med , vol.28 , pp. 365-373
    • Benítez, F.1    Najafian, N.2
  • 5
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin-2 in FOXP3-expressing regulatory T cells
    • Fontenot J.D., Rasmussen J.P., Gavin M.A., et al. A function for interleukin-2 in FOXP3-expressing regulatory T cells. Nat Immunol 2005, 6:1142-1151.
    • (2005) Nat Immunol , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3
  • 6
    • 13144281722 scopus 로고    scopus 로고
    • Defects in the interferon-gamma and interleukin-12 pathways
    • Rosenzweig S.D., Holland S.M. Defects in the interferon-gamma and interleukin-12 pathways. Immunol Rev 2005, 203:38-47.
    • (2005) Immunol Rev , vol.203 , pp. 38-47
    • Rosenzweig, S.D.1    Holland, S.M.2
  • 7
    • 84873142822 scopus 로고    scopus 로고
    • A model for harmonization flow cytometry in clinical trials
    • Maecker H.T., McCoy J.P. A model for harmonization flow cytometry in clinical trials. Nat Immunol 2010, 11:200-975.
    • (2010) Nat Immunol , vol.11 , pp. 200-975
    • Maecker, H.T.1    McCoy, J.P.2
  • 8
    • 10644278692 scopus 로고    scopus 로고
    • Enzyme-linked immunosorbent spot assay for donor-reactive interferon-gamma-producing cells identifies T-cell presensitization and correlates with graft function at 6 and 12months in renal-transplant recipients
    • Nickel P., Presber F., Bold G., et al. Enzyme-linked immunosorbent spot assay for donor-reactive interferon-gamma-producing cells identifies T-cell presensitization and correlates with graft function at 6 and 12months in renal-transplant recipients. Transplantation 2004, 78:1640-1646.
    • (2004) Transplantation , vol.78 , pp. 1640-1646
    • Nickel, P.1    Presber, F.2    Bold, G.3
  • 9
    • 37049010274 scopus 로고    scopus 로고
    • Pretransplant donor-specific interferon-gamma ELISPOT assay predicts acute rejection episodes in renal transplant recipients
    • Kim S.H., Oh E.J., Kim M.J., et al. Pretransplant donor-specific interferon-gamma ELISPOT assay predicts acute rejection episodes in renal transplant recipients. Transplant Proc 2007, 39:3057-3060.
    • (2007) Transplant Proc , vol.39 , pp. 3057-3060
    • Kim, S.H.1    Oh, E.J.2    Kim, M.J.3
  • 10
    • 48149108073 scopus 로고    scopus 로고
    • Circulating alloreactive T cells correlate with graft function in longstanding renal transplant recipients
    • Bestard O., Nickel P., Cruzado J.M., et al. Circulating alloreactive T cells correlate with graft function in longstanding renal transplant recipients. J Am Soc Nephrol 2008, 19(7):1419-1429.
    • (2008) J Am Soc Nephrol , vol.19 , Issue.7 , pp. 1419-1429
    • Bestard, O.1    Nickel, P.2    Cruzado, J.M.3
  • 11
    • 84863275042 scopus 로고    scopus 로고
    • Intracellular interferon-γ staining analysis of donor-specific T-cell responses in liver transplant recipients
    • Okanami Y., Tsujimura K., Mizuno S., et al. Intracellular interferon-γ staining analysis of donor-specific T-cell responses in liver transplant recipients. Transplant Proc 2012, 44(2):548-554.
    • (2012) Transplant Proc , vol.44 , Issue.2 , pp. 548-554
    • Okanami, Y.1    Tsujimura, K.2    Mizuno, S.3
  • 12
    • 78149284732 scopus 로고    scopus 로고
    • Biomarkers of immunosuppression status in liver transplant recipients undergoing weaning of immunosuppressive therapy
    • Millán O., Benitez C., Guillen D., et al. Biomarkers of immunosuppression status in liver transplant recipients undergoing weaning of immunosuppressive therapy. Clin Immunol 2010, 137:337-346.
    • (2010) Clin Immunol , vol.137 , pp. 337-346
    • Millán, O.1    Benitez, C.2    Guillen, D.3
  • 13
    • 3042651960 scopus 로고    scopus 로고
    • + T cell IL-2 production by anti-calcineurin drugs during acute liver allograft rejection
    • + T cell IL-2 production by anti-calcineurin drugs during acute liver allograft rejection. Transplantation 2004, 77:1815-1820.
    • (2004) Transplantation , vol.77 , pp. 1815-1820
    • Boleslawski, E.1    Conti, F.2    Sanquer, S.3
  • 14
    • 70349918127 scopus 로고    scopus 로고
    • Interleukin-2 in CD8+ T cells correlates with Banff score during organ rejection in liver transplant recipients
    • Akoglu B., Kriener S., Martens S., et al. Interleukin-2 in CD8+ T cells correlates with Banff score during organ rejection in liver transplant recipients. Clin Exp Med 2009, 9(4):259-262.
    • (2009) Clin Exp Med , vol.9 , Issue.4 , pp. 259-262
    • Akoglu, B.1    Kriener, S.2    Martens, S.3
  • 15
    • 29544444906 scopus 로고    scopus 로고
    • Pharmacodynamic monitoring of the conversion of cyclosporine to tacrolimus in heart and lung transplant recipients
    • Barten M.J., Rahmel A., Garbade J., et al. Pharmacodynamic monitoring of the conversion of cyclosporine to tacrolimus in heart and lung transplant recipients. Transplant Proc 2005, 37(10):4532-4534.
    • (2005) Transplant Proc , vol.37 , Issue.10 , pp. 4532-4534
    • Barten, M.J.1    Rahmel, A.2    Garbade, J.3
  • 16
    • 0034900704 scopus 로고    scopus 로고
    • Quantitation of immunosuppression by tacrolimus using flow cytometric analysis of interleukin-2 and interferon-gamma inhibition in CD8(-) and CD8(+) peripheral blood T cells
    • Ahmed M., Venkataraman R., Logar A.J., et al. Quantitation of immunosuppression by tacrolimus using flow cytometric analysis of interleukin-2 and interferon-gamma inhibition in CD8(-) and CD8(+) peripheral blood T cells. Ther Drug Monit 2001, 23:354-362.
    • (2001) Ther Drug Monit , vol.23 , pp. 354-362
    • Ahmed, M.1    Venkataraman, R.2    Logar, A.J.3
  • 17
    • 84873138750 scopus 로고    scopus 로고
    • Specific method for simultaneous determination of calcineurin and mTOR inhibitor immunosuppressants in human whole blood by LC/MS/MS. J Chromat B, submitted for publication.
    • Guillen D, Millán O, Rimola A, Brunet M. Specific method for simultaneous determination of calcineurin and mTOR inhibitor immunosuppressants in human whole blood by LC/MS/MS. J Chromat B, submitted for publication.
    • Guillen, D.1    Millán, O.2    Rimola, A.3    Brunet, M.4
  • 18
    • 33644616547 scopus 로고    scopus 로고
    • Sequential determination of pharmacokinetics of mycophenolic acid in liver transplant patients treated with mycophenolate mofetil
    • Brunet M., Cirera I., Martorell J., Vidal E., Millán O., Jiménez O., et al. Sequential determination of pharmacokinetics of mycophenolic acid in liver transplant patients treated with mycophenolate mofetil. Transplantation 2006, 81:541-546.
    • (2006) Transplantation , vol.81 , pp. 541-546
    • Brunet, M.1    Cirera, I.2    Martorell, J.3    Vidal, E.4    Millán, O.5    Jiménez, O.6
  • 19
    • 67651115805 scopus 로고    scopus 로고
    • The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: the Symphony pharmacokinetic substudy
    • Grinyó J.M., Ekberg H., Mamelok R.D., et al. The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: the Symphony pharmacokinetic substudy. Nephrol Dial Transplant 2009, 24(7):2269-2276.
    • (2009) Nephrol Dial Transplant , vol.24 , Issue.7 , pp. 2269-2276
    • Grinyó, J.M.1    Ekberg, H.2    Mamelok, R.D.3
  • 20
    • 77957258769 scopus 로고    scopus 로고
    • Biomarkers as a tool for management of immunosuppression in transplant patients
    • Wieland E., Olbricht C.J., Süsal C., et al. Biomarkers as a tool for management of immunosuppression in transplant patients. Ther Drug Monit 2010, 72:560-572.
    • (2010) Ther Drug Monit , vol.72 , pp. 560-572
    • Wieland, E.1    Olbricht, C.J.2    Süsal, C.3
  • 21
    • 34548392743 scopus 로고    scopus 로고
    • T-cell function monitoring in stable renal transplant patients treated with sirolimus monotherapy
    • Brunet M., Campistol J.M., Diekmann F., Guillen D., Millán O. T-cell function monitoring in stable renal transplant patients treated with sirolimus monotherapy. Mol Diagn Ther 2007, 11:247-256.
    • (2007) Mol Diagn Ther , vol.11 , pp. 247-256
    • Brunet, M.1    Campistol, J.M.2    Diekmann, F.3    Guillen, D.4    Millán, O.5
  • 22
    • 41149157985 scopus 로고    scopus 로고
    • Pretransplant donor-specific and non-specific immune parameters associated with early acute rejection
    • Reinsmoen N.L., Cornett K.M., Kloehn R., et al. Pretransplant donor-specific and non-specific immune parameters associated with early acute rejection. Transplantation 2008, 85:462-470.
    • (2008) Transplantation , vol.85 , pp. 462-470
    • Reinsmoen, N.L.1    Cornett, K.M.2    Kloehn, R.3
  • 23
    • 33748690103 scopus 로고    scopus 로고
    • Assessing relative risks of infection and rejection: a meta-analysis using an immune function assay
    • Kowalski R.J., Post D.R., Mannon R.B., et al. Assessing relative risks of infection and rejection: a meta-analysis using an immune function assay. Transplantation 2006, 82:663-668.
    • (2006) Transplantation , vol.82 , pp. 663-668
    • Kowalski, R.J.1    Post, D.R.2    Mannon, R.B.3
  • 24
    • 0033566737 scopus 로고    scopus 로고
    • Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes
    • Heeger P.S., Greenspan N.S., Kuhlenschmidt S., et al. Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes. J Immunol 1999, 163:2267-2275.
    • (1999) J Immunol , vol.163 , pp. 2267-2275
    • Heeger, P.S.1    Greenspan, N.S.2    Kuhlenschmidt, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.