Heavy metal-induced metallothionein expression is regulated by specific protein phosphatase 2A complexes

Journal of Biological Chemistry

Volumn 289, Issue 32, 2014, Pages 22413-22426

  Chen, Liping ^a   Ma, Lu ^a   Bai, Qing ^a   Zhu, Xiaonian ^a   Zhang, Jinmiao ^a   Wei, Qing ^a   Li, Daochuan ^a   Gao, Chen ^a   Li, Jie ^a   Zhang, Zhengbao ^a   Liu, Caixia ^a   He, Zhini ^a   Zeng, Xiaowen ^a   Zhang, Aihua ^b   Qu, Weidong ^c   Zhuang, Zhixiong ^d   Chen, Wen ^a   Xiao, Yongmei ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUIZHOU MEDICAL UNIVERSITY   (China)

^c FUDAN UNIVERSITY   (China)

^d SHENZHEN CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGY;

CELLULAR STRESS RESPONSE; METAL STRESS; METALLOTHIONEINS; MOLECULAR MECHANISM; PROTEIN PHOSPHATASE 2A; SIGNALING PATHWAYS; TRANSACTIVATION;

HEAVY METALS;

DNA BINDING PROTEIN; HEAVY METAL; METALLOTHIONEIN; MULTIENZYME COMPLEX; PHOSPHOPROTEIN PHOSPHATASE 2; PROTEIN SUBUNIT; RECOMBINANT PROTEIN; THREONINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MTF-1;

ACTIVE TRANSPORT; AMINO ACID SUBSTITUTION; BIOSYNTHESIS; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; PROTEIN SUBUNIT; SITE DIRECTED MUTAGENESIS; TOXICITY;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SUBSTITUTION; DNA-BINDING PROTEINS; GENE EXPRESSION; HEK293 CELLS; HUMANS; METALLOTHIONEIN; METALS, HEAVY; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN PHOSPHATASE 2; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; STRESS, PHYSIOLOGICAL; THREONINE; TRANSCRIPTION FACTORS;

EID: 84905841279     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.548677     Document Type: Article

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