Kit regulates HSC engraftment across the human-mouse species barrier

Cell Stem Cell

Volumn 15, Issue 2, 2014, Pages 227-238

  Cosgun, Kadriye Nehir ^a   Rahmig, Susann ^a   Mende, Nicole ^a   Reinke, Sören ^a   Hauber, Ilona ^b   Schäfer, Carola ^b   Petzold, Anke ^a   Weisbach, Henry ^a,f   Heidkamp, Gordon ^c   Purbojo, Ariawan ^c   Cesnjevar, Robert ^c   Platz, Alexander ^d   Bornhäuser, Martin ^a   Schmitz, Marc ^a   Dudziak, Diana ^c   Hauber, Joachim ^b   Kirberg, Jörg ^e   Waskow, Claudia ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^c UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^d DKMS Lifeline Cord Blood Bank   (Germany)

^e PAUL EHRLICH INSTITUT   (Germany)

^f CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

KIT RECEPTOR; RECEPTOR; UNCLASSIFIED DRUG; MESSENGER RNA; STEM CELL FACTOR;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL RENEWAL; CELL SUBPOPULATION; CONDITIONING; CONTROLLED STUDY; ENGRAFTMENT; GENE MUTATION; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; IRRADIATION; MOUSE; MOUSE STRAIN; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; C57BL MOUSE; CELL LINEAGE; CROSS BREEDING; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; FETUS BLOOD; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; LYMPHOCYTE; METABOLISM; MUTATION; PROCEDURES; SPECIES DIFFERENCE; THYMOCYTE; TIME; TRANSGENIC MOUSE;

MUS;

ANIMALS; CELL LINEAGE; CROSSES, GENETIC; ENZYME-LINKED IMMUNOSORBENT ASSAY; FETAL BLOOD; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; LYMPHOCYTES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; RNA, MESSENGER; SPECIES SPECIFICITY; STEM CELL FACTOR; THYMOCYTES; TIME FACTORS;

EID: 84905815023     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2014.06.001     Document Type: Article

References (35)

1. K. Arndt, T. Grinenko, N. Mende, D. Reichert, M. Portz, T. Ripich, P. Carmeliet, D. Corbeil, and C. Waskow CD133 is a modifier of hematopoietic progenitor frequencies but is dispensable for the maintenance of mouse hematopoietic stem cells Proc. Natl. Acad. Sci. USA 110 2013 5582 5587
2. M.A. Brehm, A. Cuthbert, C. Yang, D.M. Miller, P. DiIorio, J. Laning, L. Burzenski, B. Gott, O. Foreman, and A. Kavirayani et al. Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation Clin. Immunol. 135 2010 84 98
3. M.A. Brehm, W.J. Racki, J. Leif, L. Burzenski, V. Hosur, A. Wetmore, B. Gott, M. Herlihy, R. Ignotz, and R. Dunn et al. Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2rγ null mice is enhanced by transgenic expression of membrane-bound human SCF Blood 119 2012 2778 2788
4. C.L. Carbonneau, G. Despars, S. Rojas-Sutterlin, A. Fortin, O. Le, T. Hoang, and C.M. Beauséjour Ionizing radiation-induced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis Blood 119 2012 717 726
5. S. Doulatov, F. Notta, E. Laurenti, and J.E. Dick Hematopoiesis: a human perspective Cell Stem Cell 10 2012 120 136
6. P. Ghia, E. ten Boekel, E. Sanz, A. de la Hera, A. Rolink, and F. Melchers Ordering of human bone marrow B lymphocyte precursors by single-cell polymerase chain reaction analyses of the rearrangement status of the immunoglobulin H and L chain gene loci J. Exp. Med. 184 1996 2217 2229
7. T. Grinenko, K. Arndt, M. Portz, N. Mende, M. Günther, K.N. Cosgun, D. Alexopoulou, N. Lakshmanaperumal, I. Henry, A. Dahl, and C. Waskow Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells J. Exp. Med. 211 2014 209 215
8. M.D. Hazenberg, S.A. Otto, J.W. Cohen Stuart, M.C. Verschuren, J.C. Borleffs, C.A. Boucher, R.A. Coutinho, J.M. Lange, T.F. Rinke de Wit, and A. Tsegaye et al. Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection Nat. Med. 6 2000 1036 1042
9. Y. Hu, and G.K. Smyth ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays J. Immunol. Methods 347 2009 70 78
10. F. Ishikawa, M. Yasukawa, B. Lyons, S. Yoshida, T. Miyamoto, G. Yoshimoto, T. Watanabe, K. Akashi, L.D. Shultz, and M. Harada Development of functional human blood and immune systems in NOD/SCID/IL2 receptor gamma chain(null) mice Blood 106 2005 1565 1573
11. M. Ito, H. Hiramatsu, K. Kobayashi, K. Suzue, M. Kawahata, K. Hioki, Y. Ueyama, Y. Koyanagi, K. Sugamura, and K. Tsuji et al. NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells Blood 100 2002 3175 3182
12. I. Kawashima, E.D. Zanjani, G. Almaida-Porada, A.W. Flake, H. Zeng, and M. Ogawa CD34+ human marrow cells that express low levels of Kit protein are enriched for long-term marrow-engrafting cells Blood 87 1996 4136 4142
13. J. Kirberg, A. Berns, and H. von Boehmer Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules J. Exp. Med. 186 1997 1269 1275
14. R. Majeti, C.Y. Park, and I.L. Weissman Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood Cell Stem Cell 1 2007 635 645
15. P.H. Miller, A.M. Cheung, P.A. Beer, D.J. Knapp, K. Dhillon, G. Rabu, S. Rostamirad, R.K. Humphries, and C.J. Eaves Enhanced normal short-term human myelopoiesis in mice engineered to express human-specific myeloid growth factors Blood 121 2013 e1 e4
16. F.E. Nicolini, J.D. Cashman, D.E. Hogge, R.K. Humphries, and C.J. Eaves NOD/SCID mice engineered to express human IL-3, GM-CSF and Steel factor constitutively mobilize engrafted human progenitors and compromise human stem cell regeneration Leukemia 18 2004 341 347
17. S.K. Nilsson, M.S. Dooner, C.Y. Tiarks, H.U. Weier, and P.J. Quesenberry Potential and distribution of transplanted hematopoietic stem cells in a nonablated mouse model Blood 89 1997 4013 4020
18. K. Nocka, J.C. Tan, E. Chiu, T.Y. Chu, P. Ray, P. Traktman, and P. Besmer Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W EMBO J. 9 1990 1805 1813
19. A. Rongvaux, T. Willinger, H. Takizawa, C. Rathinam, W. Auerbach, A.J. Murphy, D.M. Valenzuela, G.D. Yancopoulos, E.E. Eynon, and S. Stevens et al. Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo Proc. Natl. Acad. Sci. USA 108 2011 2378 2383
20. A. Rongvaux, T. Willinger, J. Martinek, T. Strowig, S.V. Gearty, L.L. Teichmann, Y. Saito, F. Marches, S. Halene, and A.K. Palucka et al. Development and function of human innate immune cells in a humanized mouse model Nat. Biotechnol. 32 2014 364 372
21. F.A. Scheeren, M. Nagasawa, K. Weijer, T. Cupedo, J. Kirberg, N. Legrand, and H. Spits T cell-independent development and induction of somatic hypermutation in human IgM+ IgD+ CD27+ B cells J. Exp. Med. 205 2008 2033 2042
22. L. Shao, W. Feng, H. Li, D. Gardner, Y. Luo, Y. Wang, L. Liu, A. Meng, N.E. Sharpless, and D. Zhou Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner Blood 123 2014 3105 3115
23. H. Shen, H. Yu, P.H. Liang, H. Cheng, R. XuFeng, Y. Yuan, P. Zhang, C.A. Smith, and T. Cheng An acute negative bystander effect of γ-irradiated recipients on transplanted hematopoietic stem cells Blood 119 2012 3629 3637
24. J.Y. Shin, W. Hu, M. Naramura, and C.Y. Park High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias J. Exp. Med. 211 2014 217 231
25. L.D. Shultz, F. Ishikawa, and D.L. Greiner Humanized mice in translational biomedical research Nat. Rev. Immunol. 7 2007 118 130
26. L.D. Shultz, M.A. Brehm, J.V. Garcia-Martinez, and D.L. Greiner Humanized mice for immune system investigation: progress, promise and challenges Nat. Rev. Immunol. 12 2012 786 798
27. T. Strowig, A. Rongvaux, C. Rathinam, H. Takizawa, C. Borsotti, W. Philbrick, E.E. Eynon, M.G. Manz, and R.A. Flavell Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice Proc. Natl. Acad. Sci. USA 108 2011 13218 13223
28. S. Takagi, Y. Saito, A. Hijikata, S. Tanaka, T. Watanabe, T. Hasegawa, S. Mochizuki, J. Kunisawa, H. Kiyono, and H. Koseki et al. Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation Blood 119 2012 2768 2777
29. K. Takenaka, T.K. Prasolava, J.C. Wang, S.M. Mortin-Toth, S. Khalouei, O.I. Gan, J.E. Dick, and J.S. Danska Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells Nat. Immunol. 8 2007 1313 1323
30. E. Traggiai, L. Chicha, L. Mazzucchelli, L. Bronz, J.C. Piffaretti, A. Lanzavecchia, and M.G. Manz Development of a human adaptive immune system in cord blood cell-transplanted mice Science 304 2004 104 107
31. M. von Bonin, M. Wermke, K.N. Cosgun, C. Thiede, M. Bornhauser, G. Wagemaker, and C. Waskow In vivo expansion of co-transplanted T cells impacts on tumor re-initiating activity of human acute myeloid leukemia in NSG mice PLoS ONE 8 2013 e60680
32. C. Waskow, G. Terszowski, C. Costa, M. Gassmann, and H.R. Rodewald Rescue of lethal c-KitW/W mice by erythropoietin Blood 104 2004 1688 1695
33. C. Waskow, K. Liu, G. Darrasse-Jèze, P. Guermonprez, F. Ginhoux, M. Merad, T. Shengelia, K. Yao, and M. Nussenzweig The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues Nat. Immunol. 9 2008 676 683
34. C. Waskow, V. Madan, S. Bartels, C. Costa, R. Blasig, and H.R. Rodewald Hematopoietic stem cell transplantation without irradiation Nat. Methods 6 2009 267 269
35. T. Willinger, A. Rongvaux, T. Strowig, M.G. Manz, and R.A. Flavell Improving human hemato-lymphoid-system mice by cytokine knock-in gene replacement Trends Immunol. 32 2011 321 327