Molecular mechanism of ligand recognition by membrane transport protein, Mhp1

EMBO Journal

Volumn 33, Issue 16, 2014, Pages 1831-1844

  Simmons, Katie J ^a   Jackson, Scott M ^a   Brueckner, Florian ^b,c,d,h   Patching, Simon G ^a   Beckstein, Oliver ^e,f   Ivanova, Ekaterina ^a   Geng, Tian ^b,c,d   Weyand, Simone ^b,c,d   Drew, David ^c   Lanigan, Joseph ^a   Sharples, David J ^a   Sansom, Mark S P ^f   Iwata, So ^b,c,d   Fishwick, Colin W G ^a   Johnson, A Peter ^a   Cameron, Alexander D ^b,c,g   Henderson, Peter J F ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b Membrane Protein Laboratory   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d RUTHERFORD APPLETON LABORATORY   (United Kingdom)

^e ARIZONA STATE UNIVERSITY   (United States)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g UNIVERSITY OF WARWICK   (United Kingdom)

^h PAUL SCHERRER INSTITUTE   (Switzerland)

Author keywords

five helix inverted repeat superfamily; hydantoin; membrane transport; Mhp1; molecular recognition; nucleobase cation symport, NCS1, family

Indexed keywords

FIVE HELIX INVERTED REPEAT SUPERFAMILY; HYDANTOIN; MEMBRANE TRANSPORT; MHP1; MOLECULAR RECOGNITION; NUCLEOBASE-CATION-SYMPORT, NCS1, FAMILY;

BACTERIAL PROTEINS; BINDING SITES; BIOLOGICAL TRANSPORT; CRYSTALLOGRAPHY, X-RAY; HYDANTOINS; HYDROGEN BONDING; LIGANDS; MICROCOCCACEAE; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84905752809     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201387557     Document Type: Article

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