Structure-function relationship of a plant NCS1 member - Homology modeling and mutagenesis identified residues critical for substrate specificity of PLUTO, a nucleobase transporter from arabidopsis

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Witz, Sandra ^a   Panwar, Pankaj ^b   Schober, Markus ^a   Deppe, Johannes ^a   Pasha, Farhan Ahmad ^c   Lemieux, M Joanne ^b   Moḧlmann, Torsten ^a  

^a Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

^b UNIVERSITY OF ALBERTA   (Canada)

^c KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CARRIER PROTEIN; GUANINE; NUCLEOBASE TRANSPORTER; NUCLEOBASE TRANSPORTER PLUTO; PROTEIN MHP 1; UNCLASSIFIED DRUG; URACIL; ARABIDOPSIS PROTEIN; NCS1 PROTEIN, ARABIDOPSIS;

AMINO ACID TRANSPORT; ARABIDOPSIS; ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME SPECIFICITY; MICROBACTERIUM LIQUEFACIEN; MOLECULAR DYNAMICS; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; BINDING COMPETITION; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR DOCKING; MOLECULAR GENETICS; MUTATION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ARABIDOPSIS; ARABIDOPSIS PROTEINS; BINDING, COMPETITIVE; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEOBASE TRANSPORT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 84898009362     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091343     Document Type: Article

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