메뉴 건너뛰기




Volumn 8, Issue AUG, 2014, Pages

High-fat-diet-induced weight gain ameliorates bone loss without exacerbating AβPP processing and cognition in female APP/PS1 mice

Author keywords

Alzheimer's disease; Bone mineral density; Leptin; Osteoporosis; Weight gain

Indexed keywords


EID: 84905693592     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2014.00225     Document Type: Article
Times cited : (25)

References (71)
  • 1
    • 2942722529 scopus 로고    scopus 로고
    • Bone biomechanical properties in LRP5 mutant mice
    • doi:10.1016/j.bone.2004.02.018
    • Akhter, M., Wells, D., Short, S., Cullen, D., Johnson, M., Haynatzki, G., et al. Bone biomechanical properties in LRP5 mutant mice. Bone 35,162-169. doi:10.1016/j.bone.2004.02.018
    • Bone , vol.35 , pp. 162-169
    • Akhter, M.1    Wells, D.2    Short, S.3    Cullen, D.4    Johnson, M.5    Haynatzki, G.6
  • 3
    • 84897481309 scopus 로고    scopus 로고
    • Alzheimer's disease facts and figures
    • Alzheimer's Association. (2014), doi:10.1016/j.jalz.2014.02.001
    • Alzheimer's Association. (2014). 2014 Alzheimer's disease facts and figures. lzheimersDement. 10,e47-e92. doi:10.1016/j.jalz.2014.02.001
    • (2014) LzheimersDement , vol.10
  • 4
    • 0032786697 scopus 로고    scopus 로고
    • Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies. EURODEM Incidence Research Group
    • doi:10.1212/WNL.53.9.1992
    • Andersen, K., Launer, L. J., Dewey, M. E., Letenneur, L., Ott, A., Copeland, J. R., et al. (1999). Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies. EURODEM Incidence Research Group. Neurology 53, 1992-1997. doi:10.1212/WNL.53.9.1992
    • (1999) Neurology , vol.53 , pp. 1992-1997
    • Andersen, K.1    Launer, L.J.2    Dewey, M.E.3    Letenneur, L.4    Ott, A.5    Copeland, J.R.6
  • 5
    • 84902370768 scopus 로고    scopus 로고
    • Bone structure and estimated bone strength in obese patients evaluated by high-resolution peripheral quantitative computed tomography
    • doi:10.1007/s00223-014-9857-4
    • Andersen, S., Frederiksen, K. D., Hansen, S., Brixen, K., Gram, J., and St0ving, R. K. (2014). Bone structure and estimated bone strength in obese patients evaluated by high-resolution peripheral quantitative computed tomography. Calcif. Tissue Int. 95,19-28. doi:10.1007/s00223-014-9857-4
    • (2014) Calcif. Tissue Int , vol.95 , pp. 19-28
    • Andersen, S.1    Frederiksen, K.D.2    Hansen, S.3    Brixen, K.4    Gram, J.5    Stoving, R.K.6
  • 6
    • 84886611064 scopus 로고    scopus 로고
    • Sex-specific effects ofhigh fat diet on indices of metabolic syndrome in 3xTg-AD mice: Implications for Alzheimer's disease
    • doi:10.1371/journal.pone.0078554
    • Barron, A. M., Rosario, E. R., Elteriefi, R., and Pike, C. J. (2013). Sex-specific effects ofhigh fat diet on indices of metabolic syndrome in 3xTg-AD mice: implications for Alzheimer's disease. PLoS ONE 8:e78554. doi:10.1371/journal.pone.0078554
    • (2013) PLoS ONE , vol.8
    • Barron, A.M.1    Rosario, E.R.2    Elteriefi, R.3    Pike, C.J.4
  • 7
    • 84890806968 scopus 로고    scopus 로고
    • Dysregulation ofleptin signaling inAlzheimer disease: Evidence for neuronal leptin resistance
    • doi:10.1111/jnc.12380
    • Bonda, D. J., Stone, J. G., Torres, S. L., Siedlak, S. L., Perry, G., Kryscio, R., et al. (2013). Dysregulation ofleptin signaling inAlzheimer disease: evidence for neuronal leptin resistance. J. Neurochem. 128, 162-172. doi:10.1111/jnc.12380
    • (2013) J. Neurochem , vol.128 , pp. 162-172
    • Bonda, D.J.1    Stone, J.G.2    Torres, S.L.3    Siedlak, S.L.4    Perry, G.5    Kryscio, R.6
  • 8
    • 34248225957 scopus 로고    scopus 로고
    • Various effects of antidepressant drugs on bone microarchitecture, mechanical properties and bone remodeling
    • doi:10.1016/j.taap.2007.02.005
    • Bonnet, N., Bernard, P., Beaupied, H., Bizot, J., Trovero, F., Courteix, D., et al. (2007). Various effects of antidepressant drugs on bone microarchitecture, mechanical properties and bone remodeling. Toxicol. Appl. Pharmacol. 221, 111-118. doi:10.1016/j.taap.2007.02.005
    • (2007) Toxicol. Appl. Pharmacol , vol.221 , pp. 111-118
    • Bonnet, N.1    Bernard, P.2    Beaupied, H.3    Bizot, J.4    Trovero, F.5    Courteix, D.6
  • 9
    • 0030833055 scopus 로고    scopus 로고
    • Accelerated amyloid deposition in the brains of transgenic mice oexpressing mutant presenilin 1 and amyloid precursor proteins
    • doi:10.1016/S0896-6273(00)80974-5
    • Borchelt, D. R., Ratovitski, T., van Lare, J., Lee, M. K., Gonzales, V., Jenkins, N. A., et al. (1997). Accelerated amyloid deposition in the brains of transgenic mice oexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19, 939-945. doi:10.1016/S0896-6273(00)80974-5
    • (1997) Neuron , vol.19 , pp. 939-945
    • Borchelt, D.R.1    Ratovitski, T.2    van Lare, J.3    Lee, M.K.4    Gonzales, V.5    Jenkins, N.A.6
  • 10
    • 77954756294 scopus 로고    scopus 로고
    • Guidelines for assessment of bone microstructure in rodents using micro-computed tomography
    • doi:10.1002/jbmr.141
    • Bouxsein, M. L., Boyd, S. K., Christiansen, B. A., Guldberg, R. E., Jepsen, K. J., and Müller, R. (2010). Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. J. Bone Miner. Res. 25, 1468-1486. doi:10.1002/jbmr.141
    • (2010) J. Bone Miner. Res , vol.25 , pp. 1468-1486
    • Bouxsein, M.L.1    Boyd, S.K.2    Christiansen, B.A.3    Guldberg, R.E.4    Jepsen, K.J.5    Müller, R.6
  • 11
    • 84878699428 scopus 로고    scopus 로고
    • Next generation therapeutics for Alzheimer's disease
    • doi:10.1002/emmm.201202307
    • Bredesen, D. E., and John, V. (2013). Next generation therapeutics for Alzheimer's disease. EMBOMol. Med. 5,795-798. doi:10.1002/emmm.201202307
    • (2013) EMBOMol. Med , vol.5 , pp. 795-798
    • Bredesen, D.E.1    John, V.2
  • 12
    • 0034914287 scopus 로고    scopus 로고
    • Leptin reduces ovariectomy-induced bone loss in rats
    • doi:10.1210/endo.142.8.8346
    • Burguera, B., Hofbauer, L. C., Thomas, T., Gori, F., Evans, G. L., Khosla, S., etal. Leptin reduces ovariectomy-induced bone loss in rats. Endocrinology 142, 3546-3553. doi:10.1210/endo.142.8.8346
    • Endocrinology , vol.142 , pp. 3546-3553
    • Burguera, B.1    Hofbauer, L.C.2    Thomas, T.3    Gori, F.4    Evans, G.L.5    Khosla, S.6
  • 13
    • 13344295079 scopus 로고    scopus 로고
    • Serum immunoreactive-leptin concentrations in normal-weight and obese humans
    • doi:10.1056/NEJM199602013340503
    • Considine, R. V., Sinha, M. K., Heiman, M. L., Kriauciunas, A., Stephens, T. W., Nyce, M. R., et al. (1996). Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N. Engl. J. Med. 334, 292-295. doi:10.1056/NEJM199602013340503
    • (1996) N. Engl. J. Med , vol.334 , pp. 292-295
    • Considine, R.V.1    Sinha, M.K.2    Heiman, M.L.3    Kriauciunas, A.4    Stephens, T.W.5    Nyce, M.R.6
  • 14
    • 84896741355 scopus 로고    scopus 로고
    • Diet studies challenge thinking on proteins versus carbs
    • doi:10.1126/science.343.6175.1068
    • Couzin-Frankel, J. (2014). Diet studies challenge thinking on proteins versus carbs. cience 343, 1068. doi:10.1126/science.343.6175.1068
    • (2014) Cience , pp. 343
    • Couzin-Frankel, J.1
  • 15
    • 0031023198 scopus 로고    scopus 로고
    • Weight loss in people with Alzheimer's disease: A prospective population based analysis
    • doi:10.1136/ bmj.314.7075.178
    • Cronin-Stubbs, D., Beckett, L. A., Scherr, P. A., Field, T. S., Chown, M. J., Pilgrim, D. M., et al. (1997). Weight loss in people with Alzheimer's disease: a prospective population based analysis. Br. Med. J. 314, 171-174. doi:10.1136/ bmj.314.7075.178
    • (1997) Br. Med. J , vol.314 , pp. 171-174
    • Cronin-Stubbs, D.1    Beckett, L.A.2    Scherr, P.A.3    Field, T.S.4    Chown, M.J.5    Pilgrim, D.M.6
  • 16
    • 27444442003 scopus 로고    scopus 로고
    • Body mass index as a predictor of fracture risk: A meta-analysis
    • doi:10.1007/s00198-005-1863-y
    • De Laet, C., Kanis, J., Oden, A., Johanson, H., Johnell, O., Delmas, P., et al. (2005). Body mass index as a predictor of fracture risk: a meta-analysis. Osteoporos. Int. 16,1330-1338. doi:10.1007/s00198-005-1863-y
    • (2005) Osteoporos. Int , vol.16 , pp. 1330-1338
    • de Laet, C.1    Kanis, J.2    Oden, A.3    Johanson, H.4    Johnell, O.5    Delmas, P.6
  • 17
    • 9644269024 scopus 로고    scopus 로고
    • Hippocampal lesions, species-typical behaviours and anxiety in mice
    • doi:10.1016/j. bbr.2004.05.027
    • Deacon, R. M., and Rawlins, J. N. P. (2005). Hippocampal lesions, species-typical behaviours and anxiety in mice. Behav. Brain Res. 156, 241-249. doi:10.1016/j. bbr.2004.05.027
    • (2005) Behav. Brain Res , vol.156 , pp. 241-249
    • Deacon, R.M.1    Rawlins, J.N.P.2
  • 19
    • 67650403445 scopus 로고    scopus 로고
    • Central obesity and increased risk of dementia more than three decades later
    • doi:10.1212/01.wnl.0000343499. 72241.ea
    • Farooki, A. (2009). Central obesity and increased risk of dementia more than three decades later. Neurology 72, 1030-1031. doi:10.1212/01.wnl.0000343499. 72241.ea
    • (2009) Neurology , vol.72 , pp. 1030-1031
    • Farooki, A.1
  • 20
    • 0027310187 scopus 로고
    • Effects of weight and body mass index on bone mineral density in men and women: The Framingham study
    • doi:10.1002/jbmr. 5650080507
    • Felson, D. T., Zhang, Y., Hannan, M. T., and Anderson, J. J. (1993). Effects of weight and body mass index on bone mineral density in men and women: the Framingham study. J. Bone Miner. Res. 8, 567-573. doi:10.1002/jbmr. 5650080507
    • (1993) J. Bone Miner. Res , vol.8 , pp. 567-573
    • Felson, D.T.1    Zhang, Y.2    Hannan, M.T.3    Anderson, J.J.4
  • 21
    • 84871784819 scopus 로고    scopus 로고
    • Association of all-cause mortality with overweight and obesity using standard body mass index categories: A systematic review and meta-analysis
    • doi:10.1001/jama.2012.113905
    • Flegal, K. M., Kit, B. K., Orpana, H., and Graubard, B. I. (2013). Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA 309, 71-82. doi:10.1001/jama.2012.113905
    • (2013) JAMA , vol.309 , pp. 71-82
    • Flegal, K.M.1    Kit, B.K.2    Orpana, H.3    Graubard, B.I.4
  • 22
    • 0028793697 scopus 로고
    • Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
    • doi:10.1038/ nm1295-1311
    • Frederich, R. C., Hamann, A., Anderson, S., Löllmann, B., Lowell, B. B., and Flier, J. S. (1995). Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat. Med. 1, 1311-1314. doi:10.1038/ nm1295-1311
    • (1995) Nat. Med , vol.1 , pp. 1311-1314
    • Frederich, R.C.1    Hamann, A.2    Anderson, S.3    Löllmann, B.4    Lowell, B.B.5    Flier, J.S.6
  • 23
    • 33750819632 scopus 로고    scopus 로고
    • Characterization of amyloid deposition in the APP- swe/PS1dE9 mouse model of Alzheimer disease
    • doi:10.1016/j.nbd.2006.08.017
    • Garcia-Alloza, M., Robbins, E. M., Zhang-Nunes, S. X., Purcell, S. M., Betensky, R. A., Raju, S., et al. (2006). Characterization of amyloid deposition in the APP- swe/PS1dE9 mouse model of Alzheimer disease. Neurobiol. Dis. 24, 516-524. doi:10.1016/j.nbd.2006.08.017
    • (2006) Neurobiol. Dis , vol.24 , pp. 516-524
    • Garcia-Alloza, M.1    Robbins, E.M.2    Zhang-Nunes, S.X.3    Purcell, S.M.4    Betensky, R.A.5    Raju, S.6
  • 24
    • 0032167861 scopus 로고    scopus 로고
    • A new continuous alternation task in T-maze detects hippocampal dysfunction in mice: A strain comparison and lesion study
    • Gerlai,R, doi:10.1016/S0166-4328(97)00214-3
    • Gerlai,R. (1998). A new continuous alternation task in T-maze detects hippocampal dysfunction in mice: a strain comparison and lesion study. Behav. Brain Res. 95, 91-101. doi:10.1016/S0166-4328(97)00214-3
    • (1998) Behav. Brain Res , vol.95 , pp. 91-101
  • 25
    • 84883174365 scopus 로고    scopus 로고
    • Negative association between trunk fat, insulin resistance and skeleton in obese women
    • doi:10.4239/wjd.v4.i2.31
    • Greco, E. A., Francomano, D., Fornari, R., Marocco, C., Lubrano, C., Papa, V., et al. Negative association between trunk fat, insulin resistance and skeleton in obese women. WorldJ. Diabetes 4, 31-39. doi:10.4239/wjd.v4.i2.31
    • WorldJ. Diabetes , vol.4 , pp. 31-39
    • Greco, E.A.1    Francomano, D.2    Fornari, R.3    Marocco, C.4    Lubrano, C.5    Papa, V.6
  • 26
    • 4644286910 scopus 로고    scopus 로고
    • Diet- induced insulin resistance promotes amyloidosis in a transgenic mouse model ofAlzheimer's disease
    • doi:10.1096/fj.03-0978fje
    • Ho, L., Qin, W., Pompl, P. N., Xiang, Z., Wang, J., Zhao, Z., et al. (2004). Diet- induced insulin resistance promotes amyloidosis in a transgenic mouse model ofAlzheimer's disease. FASEB J. 18, 902-904. doi:10.1096/fj.03-0978fje
    • (2004) FASEB J , vol.18 , pp. 902-904
    • Ho, L.1    Qin, W.2    Pompl, P.N.3    Xiang, Z.4    Wang, J.5    Zhao, Z.6
  • 28
    • 79960243031 scopus 로고    scopus 로고
    • Changes in cortical bone response to high-fat diet from adolescence to adulthood in mice
    • doi:10.1007/s00198-010- 1432-x
    • Ionova-Martin, S., Wade, J., Tang, S., Shahnazari, M., Ager, III. J., Lane, N., et al. Changes in cortical bone response to high-fat diet from adolescence to adulthood in mice. Osteoporos. Int. 22, 2283-2293. doi:10.1007/s00198-010- 1432-x
    • Osteoporos. Int , vol.22 , pp. 2283-2293
    • Ionova-Martin, S.1    Wade, J.2    Tang, S.3    Shahnazari, M.4    Ager, I.I.I.J.5    Lane, N.6
  • 29
    • 0032145985 scopus 로고    scopus 로고
    • Comparison of three-point bending test and peripheral quantitative computed tomography analysis in the evaluation of the strength of mouse femur and tibia
    • doi:10.1016/S8756-3282(98)00076-3
    • Jamsa, T., Jalovaara, P., Peng, Z., Vaananen, H. K., and Tuukkanen, J. (1998). Comparison of three-point bending test and peripheral quantitative computed tomography analysis in the evaluation of the strength of mouse femur and tibia. Bone 23,155-161. doi:10.1016/S8756-3282(98)00076-3
    • (1998) Bone , vol.23 , pp. 155-161
    • Jamsa, T.1    Jalovaara, P.2    Peng, Z.3    Vaananen, H.K.4    Tuukkanen, J.5
  • 30
    • 84890944922 scopus 로고    scopus 로고
    • A Meta-analysis of the association of fracture risk and body mass indexinwomen
    • doi:10.1002/jbmr.2017
    • Johansson, H., Kanis, J. A., Oden, A., McCloskey, E., Chapurlat, R. D., Christiansen, C., et al. (2014). A Meta-analysis of the association of fracture risk and body mass indexinwomen. J. BoneMiner. Res. 29,223-233. doi:10.1002/jbmr.2017
    • (2014) J. BoneMiner. Res , vol.29 , pp. 223-233
    • Johansson, H.1    Kanis, J.A.2    Oden, A.3    McCloskey, E.4    Chapurlat, R.D.5    Christiansen, C.6
  • 31
    • 0033786473 scopus 로고    scopus 로고
    • Metabolic cardiovascular syndrome and risk of dementia in Japanese- American elderly men. The Honolulu-Asia Aging Study
    • doi:10.1161/01.ATV.20.10.2255
    • Kalmijn, S., Foley, D., White, L., Burchfiel, C. M., Curb, J. D., Petrovitch, H., et al. (2000). Metabolic cardiovascular syndrome and risk of dementia in Japanese- American elderly men. The Honolulu-Asia Aging Study. Arterioscler. Thromb. Vase. Biol. 20, 2255-2260. doi:10.1161/01.ATV.20.10.2255
    • (2000) Arterioscler. Thromb. Vase. Biol , vol.20 , pp. 2255-2260
    • Kalmijn, S.1    Foley, D.2    White, L.3    Burchfiel, C.M.4    Curb, J.D.5    Petrovitch, H.6
  • 32
    • 0030003905 scopus 로고    scopus 로고
    • Relationship between body composition and bone mass in women
    • doi:10.1002/jbmr.5650110618
    • Khosla, S., Atkinson, E. J., Riggs, B. L., and Melton, L. J. (1996).Relationship between body composition and bone mass in women. J. Bone Miner. Res. 11, 857-863. doi:10.1002/jbmr.5650110618
    • (1996) J. Bone Miner. Res , vol.11 , pp. 857-863
    • Khosla, S.1    Atkinson, E.J.2    Riggs, B.L.3    Melton, L.J.4
  • 33
    • 26444463825 scopus 로고    scopus 로고
    • Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease
    • doi:10.1001/archneur. 62.10.1556
    • Kivipelto, M., Ngandu, T., Fratiglioni, L., Viitanen, M., Kareholt, I., Winblad, B., et al. (2005). Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch. Neurol. 62, 1556-1560. doi:10.1001/archneur. 62.10.1556
    • (2005) Arch. Neurol , vol.62 , pp. 1556-1560
    • Kivipelto, M.1    Ngandu, T.2    Fratiglioni, L.3    Viitanen, M.4    Kareholt, I.5    Winblad, B.6
  • 34
    • 84876572014 scopus 로고    scopus 로고
    • Detrimental effects of diet-induced obesity on tau pathology are independent of insulin resistance in tau transgenic mice
    • doi:10.2337/db12-0866
    • Leboucher, A., Laurent, C., Fernandez-Gomez, F. J., Burnouf, S., Troquier, L., Eddark- aoui, S., et al. (2013). Detrimental effects of diet-induced obesity on tau pathology are independent of insulin resistance in tau transgenic mice. Diabetes 62, 1681-1688. doi:10.2337/db12-0866
    • (2013) Diabetes , vol.62 , pp. 1681-1688
    • Leboucher, A.1    Laurent, C.2    Fernandez-Gomez, F.J.3    Burnouf, S.4    Troquier, L.5    Eddarkaoui, S.6
  • 35
    • 84862776789 scopus 로고    scopus 로고
    • Association between cognitive impairment and bone mineral density in postmenopausal women
    • doi:10.1097/gme.0b013e31823dbec7
    • Lee, D.-Y., Na, D. L., Seo, S. W., Chin, J., Lim, S.-J., Choi, D., et al. (2012). Association between cognitive impairment and bone mineral density in postmenopausal women. Menopause 19, 636-641. doi:10.1097/gme.0b013e31823dbec7
    • (2012) Menopause , vol.19 , pp. 636-641
    • Lee, D.-Y.1    Na, D.L.2    Seo, S.W.3    Chin, J.4    Lim, S.-J.5    Choi, D.6
  • 37
    • 72549091935 scopus 로고    scopus 로고
    • Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging
    • doi:10.1001/jama.2009.1836
    • Lieb, W., Beiser, A. S., Vasan, R. S., Tan, Z. S., Au, R., Harris, T. B., et al. (2009). Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA 302, 2565-2572. doi:10.1001/jama.2009.1836
    • (2009) JAMA , vol.302 , pp. 2565-2572
    • Lieb, W.1    Beiser, A.S.2    Vasan, R.S.3    Tan, Z.S.4    Au, R.5    Harris, T.B.6
  • 38
    • 0034107525 scopus 로고    scopus 로고
    • Development of high fat diet-induced obesity and leptin resistance in C57Bl/6J mice
    • doi:10.1038/sj.ijo.0801209
    • Lin, S., Thomas, T., Storlien, L., and Huang, X. (2000). Development of high fat diet-induced obesity and leptin resistance in C57Bl/6J mice. Int. J. Obes. Relat. Metab. Disord. 24, 639-646. doi:10.1038/sj.ijo.0801209
    • (2000) Int. J. Obes. Relat. Metab. Disord , vol.24 , pp. 639-646
    • Lin, S.1    Thomas, T.2    Storlien, L.3    Huang, X.4
  • 39
    • 74949101402 scopus 로고    scopus 로고
    • Bone density and brain atrophy in early Alzheimer's disease
    • doi:10.3233/JAD-2009-1185
    • Loskutova, N., Honea, R. A., Vidoni, E. D., Brooks, W. M., and Burns, J. M. (2009). Bone density and brain atrophy in early Alzheimer's disease. J. Alzheimers Dis. 777-785. doi:10.3233/JAD-2009-1185
    • (2009) J. Alzheimers Dis , pp. 777-785
    • Loskutova, N.1    Honea, R.A.2    Vidoni, E.D.3    Brooks, W.M.4    Burns, J.M.5
  • 40
    • 13244267455 scopus 로고    scopus 로고
    • Osteoclast-derived activity in the coupling of bone formation to resorption
    • doi:10.1016/j. molmed.2004.12.004
    • Martin, T. J., and Sims, N. A. (2005). Osteoclast-derived activity in the coupling of bone formation to resorption. Trends Mol. Med. 11, 76-81. doi:10.1016/j. molmed.2004.12.004
    • (2005) Trends Mol. Med , vol.11 , pp. 76-81
    • Martin, T.J.1    Sims, N.A.2
  • 41
    • 84867575440 scopus 로고    scopus 로고
    • A high-fat-diet-induced cognitive deficit in rats that is not prevented by improving insulin sensitivity with metformin
    • doi:10.1007/s00125-012-2686-y
    • McNeilly, A. D., Williamson, R., Balfour, D. J., Stewart, C. A., and Sutherland, C. A high-fat-diet-induced cognitive deficit in rats that is not prevented by improving insulin sensitivity with metformin. Diabetologia 55, 3061-3070. doi:10.1007/s00125-012-2686-y
    • Diabetologia , vol.55 , pp. 3061-3070
    • McNeilly, A.D.1    Williamson, R.2    Balfour, D.J.3    Stewart, C.A.4    Sutherland, C.5
  • 42
    • 78149325368 scopus 로고    scopus 로고
    • High fat feeding promotes simultaneous decline in insulin sensitivity and cognitive performance in a delayed matching and non-matching to position task
    • doi:10.1016/j.bbr.2010.10.017
    • McNeilly, A. D., Williamson, R., Sutherland, C., Balfour, D. J., and Stewart, C. A. (2011). High fat feeding promotes simultaneous decline in insulin sensitivity and cognitive performance in a delayed matching and non-matching to position task. Behav. Brain Res. 217, 134-141. doi:10.1016/j.bbr.2010.10.017
    • (2011) Behav. Brain Res , vol.217 , pp. 134-141
    • McNeilly, A.D.1    Williamson, R.2    Sutherland, C.3    Balfour, D.J.4    Stewart, C.A.5
  • 43
    • 33751218916 scopus 로고    scopus 로고
    • Longitudinal study of the effects of a high-fat diet on glucose regulation, hippocampal function, and cerebral insulin sensitivity in C57BL/6 mice
    • doi:10.1016/j.bbr.2006.09.010
    • Mielke, J. G., Nicolitch, K., Avellaneda, V., Earlam, K., Ahuja, T., Mealing, G., et al. (2006). Longitudinal study of the effects of a high-fat diet on glucose regulation, hippocampal function, and cerebral insulin sensitivity in C57BL/6 mice. Behav. Brain Res. 175, 374-382. doi:10.1016/j.bbr.2006.09.010
    • (2006) Behav. Brain Res , vol.175 , pp. 374-382
    • Mielke, J.G.1    Nicolitch, K.2    Avellaneda, V.3    Earlam, K.4    Ahuja, T.5    Mealing, G.6
  • 44
    • 52449087540 scopus 로고    scopus 로고
    • Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus
    • doi:10.1096/fj.03-0978fje
    • Moroz, N., Tong, M., Longato, L., Xu, H., and De La Monte, S. M. (2008). Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus. J. Alzheimers Dis. 15, 29-44. doi:10.1096/fj.03-0978fje
    • (2008) J. Alzheimers Dis , vol.15 , pp. 29-44
    • Moroz, N.1    Tong, M.2    Longato, L.3    Xu, H.4    De La Monte, S.M.5
  • 45
    • 0032881714 scopus 로고    scopus 로고
    • Low body mass index is an important risk factor for low bone mass and increased bone loss in early postmenopausal women
    • doi:10.1359/jbmr.1999.14.9.1622
    • Ravn, P., Cizza, G., Bjarnason, N., Thompson, D., Daley, M., Wasnich, R., et al. (1999). Low body mass index is an important risk factor for low bone mass and increased bone loss in early postmenopausal women. J. Bone Miner. Res. 14, 1622-1627. doi:10.1359/jbmr.1999.14.9.1622
    • (1999) J. Bone Miner. Res , vol.14 , pp. 1622-1627
    • Ravn, P.1    Cizza, G.2    Bjarnason, N.3    Thompson, D.4    Daley, M.5    Wasnich, R.6
  • 46
    • 0036861322 scopus 로고    scopus 로고
    • Relationships among body mass, its components, andbone
    • doi:10.1016/S8756-3282(02)00864-5
    • Reid, I. R. (2002). Relationships among body mass, its components, andbone. Bone 31, 547-555. doi:10.1016/S8756-3282(02)00864-5
    • (2002) Bone , vol.31 , pp. 547-555
    • Reid, I.R.1
  • 47
    • 0026775342 scopus 로고
    • Fat mass is an important determinant of whole body bone density in premenopausal women but not in men
    • doi:10.1210/jc.75.3.779
    • Reid, I. R., Plank, L. D., and Evans, M. C. (1992). Fat mass is an important determinant of whole body bone density in premenopausal women but not in men. J. Clin. Endocrinol. Metab. 75, 779-782. doi:10.1210/jc.75.3.779
    • (1992) J. Clin. Endocrinol. Metab , vol.75 , pp. 779-782
    • Reid, I.R.1    Plank, L.D.2    Evans, M.C.3
  • 49
    • 0032402974 scopus 로고    scopus 로고
    • High prevalence of vitamin D deficiency and reduced bone mass in elderly women with Alzheimer's disease
    • doi:10.1016/S8756-3282(98)00134-3
    • Sato, Y., Asoh, T., and Oizumi, K. (1998). High prevalence of vitamin D deficiency and reduced bone mass in elderly women with Alzheimer's disease. Bone 23, 555-557. doi:10.1016/S8756-3282(98)00134-3
    • (1998) Bone , vol.23 , pp. 555-557
    • Sato, Y.1    Asoh, T.2    Oizumi, K.3
  • 50
    • 84877856832 scopus 로고    scopus 로고
    • Green tea polyphenols improve bone microarchitecture in high-fat-diet-induced obese female rats through suppressing bone formation and erosion
    • doi:10.1089/jmf.2012.0199
    • Shen, C.-L., Chyu, M.-C., Cao, J. J., and Yeh, J. K. (2013). Green tea polyphenols improve bone microarchitecture in high-fat-diet-induced obese female rats through suppressing bone formation and erosion. J. Med. Food 16, 421-427. doi:10.1089/jmf.2012.0199
    • (2013) J. Med. Food , vol.16 , pp. 421-427
    • Shen, C.-L.1    Chyu, M.-C.2    Cao, J.J.3    Yeh, J.K.4
  • 51
    • 79957533273 scopus 로고    scopus 로고
    • The role of bone marrow and visceral fat on bone metabolism
    • doi:10.1007/s11914-011- 0051-6
    • Sheu, Y., and Cauley, J. A. (2011). The role of bone marrow and visceral fat on bone metabolism. Curr. Osteoporos. Rep. 9, 67-75. doi:10.1007/s11914-011- 0051-6
    • (2011) Curr. Osteoporos. Rep , vol.9 , pp. 67-75
    • Sheu, Y.1    Cauley, J.A.2
  • 52
    • 80051800457 scopus 로고    scopus 로고
    • Long-term metreleptin treatment increases bone mineral density and content at the lumbar spine of lean hypoleptinemic women
    • doi:10.1016/j.metabol.2011.05.016
    • Sienkiewicz, E., Magkos, F., Aronis, K. N., Brinkoetter, M., Chamberland, J. P., Chou, S., et al. (2011). Long-term metreleptin treatment increases bone mineral density and content at the lumbar spine of lean hypoleptinemic women. Metab. Clin. Exp. 60,1211-1221. doi:10.1016/j.metabol.2011.05.016
    • (2011) Metab. Clin. Exp , vol.60 , pp. 1211-1221
    • Sienkiewicz, E.1    Magkos, F.2    Aronis, K.N.3    Brinkoetter, M.4    Chamberland, J.P.5    Chou, S.6
  • 53
    • 84895765028 scopus 로고    scopus 로고
    • The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice
    • doi:10.1016/j.cmet.2014.02.009
    • Solon-Biet, S. M., McMahon, A. C., Ballard, J. W. O., Ruohonen, K., Wu, L. E., Cogger, V. C., et al. (2014). The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice. Cell Metab. 418-430. doi:10.1016/j.cmet.2014.02.009
    • (2014) Cell Metab , pp. 418-430
    • Solon-Biet, S.M.1    McMahon, A.C.2    Ballard, J.W.O.3    Ruohonen, K.4    Wu, L.E.5    Cogger, V.C.6
  • 54
    • 12144268588 scopus 로고    scopus 로고
    • A 32-year prospective study of change in body weight and incident dementia: The Honolulu-Asia Aging Study
    • doi:10.1001/archneur. 62.1.55
    • Stewart, R., Masaki, K., Xue, Q.-L., Peila, R., Petrovitch, H., White, L. R., et al. (2005). A 32-year prospective study of change in body weight and incident dementia: the Honolulu-Asia Aging Study. Arch. Neurol. 62, 55-60. doi:10.1001/archneur. 62.1.55
    • (2005) Arch. Neurol , vol.62 , pp. 55-60
    • Stewart, R.1    Masaki, K.2    Xue, Q.-L.3    Peila, R.4    Petrovitch, H.5    White, L.R.6
  • 55
    • 84859718265 scopus 로고    scopus 로고
    • Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
    • doi:10.1172/JCI59903
    • Talbot, K., Wang, H.-Y., Kazi, H., Han, L.-Y., Bakshi, K. P., Stucky, A., et al. (2012). Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline. J. Clin. Invest. 122, 1316-1338. doi:10.1172/JCI59903
    • (2012) J. Clin. Invest , vol.122 , pp. 1316-1338
    • Talbot, K.1    Wang, H.-Y.2    Kazi, H.3    Han, L.-Y.4    Bakshi, K.P.5    Stucky, A.6
  • 56
    • 12144277271 scopus 로고    scopus 로고
    • Bone mineral density and the risk of Alzheimer disease
    • doi:10.1001/archneur.62.1.107
    • Tan, Z. S., Seshadri, S., Beiser, A., Zhang, Y., Felson, D., Hannan, M. T., et al. Bone mineral density and the risk of Alzheimer disease. Arch. Neurol. 62, 107-111. doi:10.1001/archneur.62.1.107
    • Arch. Neurol , vol.62 , pp. 107-111
    • Tan, Z.S.1    Seshadri, S.2    Beiser, A.3    Zhang, Y.4    Felson, D.5    Hannan, M.T.6
  • 57
    • 0032982438 scopus 로고    scopus 로고
    • Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes
    • doi:10.1210/en.140.4.1630
    • Thomas, T., Gori, F., Khosla, S., Jensen, M. D., Burguera, B., and Riggs, B. L. (1999). Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes. Endocrinology 140, 1630-1638. doi:10.1210/en.140.4.1630
    • (1999) Endocrinology , vol.140 , pp. 1630-1638
    • Thomas, T.1    Gori, F.2    Khosla, S.3    Jensen, M.D.4    Burguera, B.5    Riggs, B.L.6
  • 58
    • 0027369098 scopus 로고
    • Vertebral postmenopausal bone loss is reduced in overweight women: A longitudinal study in 155 early postmenopausal women
    • doi:10.1210/jcem. 77.3.8370689
    • Tremollieres, F., Pouilles, J., and Ribot, C. (1993). Vertebral postmenopausal bone loss is reduced in overweight women: a longitudinal study in 155 early postmenopausal women. J. Clin. Endocrinol. Metab. 77, 683-686. doi:10.1210/jcem. 77.3.8370689
    • (1993) J. Clin. Endocrinol. Metab , vol.77 , pp. 683-686
    • Tremollieres, F.1    Pouilles, J.2    Ribot, C.3
  • 59
    • 0036128709 scopus 로고    scopus 로고
    • Biomechanics of bone: Determinants of skeletal fragility and bone quality
    • doi:10.1007/s001980200000
    • Turner, C. (2002). Biomechanics of bone: determinants of skeletal fragility and bone quality. Osteoporos. Int. 13, 97-104. doi:10.1007/s001980200000
    • (2002) Osteoporos. Int , vol.13 , pp. 97-104
    • Turner, C.1
  • 60
    • 33846461062 scopus 로고    scopus 로고
    • Morris water maze: Procedures for assessing spatial and related forms of learning and memory
    • doi:10.1038/nprot.2006.116
    • Vorhees, C. V., and Williams, M. T. (2006). Morris water maze: procedures for assessing spatial and related forms of learning and memory. Nat. Protoc. 1, 848-858. doi:10.1038/nprot.2006.116
    • (2006) Nat. Protoc , vol.1 , pp. 848-858
    • Vorhees, C.V.1    Williams, M.T.2
  • 61
    • 30644469500 scopus 로고    scopus 로고
    • RANKL-RANK signaling in osteoclastogenesis and bone disease
    • doi:10.1016/j.molmed.2005.11.007
    • Wada, T., Nakashima, T., Hiroshi, N., and Penninger, J. M. (2006). RANKL-RANK signaling in osteoclastogenesis and bone disease. Trends Mol. Med. 12, 17-25. doi:10.1016/j.molmed.2005.11.007
    • (2006) Trends Mol. Med , vol.12 , pp. 17-25
    • Wada, T.1    Nakashima, T.2    Hiroshi, N.3    Penninger, J.M.4
  • 62
    • 2942585282 scopus 로고    scopus 로고
    • Hip fractures and Alzheimer's disease in elderly institutionalized Canadians
    • doi:10.1016/j. annepidem.2003.08.005
    • Weller, I., and Schatzker, J. (2004). Hip fractures and Alzheimer's disease in elderly institutionalized Canadians. Ann. Epidemiol. 14, 319-324. doi:10.1016/j. annepidem.2003.08.005
    • (2004) Ann. Epidemiol , vol.14 , pp. 319-324
    • Weller, I.1    Schatzker, J.2
  • 63
    • 0031670604 scopus 로고    scopus 로고
    • The association ofweight change in Alzheimer's disease with severity of disease and mortality: A longitudinal analysis
    • White, H., Pieper, C., and Schmader, K. (1998). The association ofweight change in Alzheimer's disease with severity of disease and mortality: a longitudinal analysis. J. Am. Geriatr. Soc. 46, 1223-1227.
    • (1998) J. Am. Geriatr. Soc , vol.46 , pp. 1223-1227
    • White, H.1    Pieper, C.2    Schmader, K.3
  • 65
    • 84884506516 scopus 로고    scopus 로고
    • Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by n-acetyl-l-cysteine
    • doi:10.1002/jbmr.1954
    • Xia, W.-F., Jung, J.-U., Shun, C., Xiong, S., Xiong, L., Shi, X.-M., et al. (2013). Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by n-acetyl-l-cysteine. J. BoneMiner. Res. 28,2122-2135. doi:10.1002/jbmr.1954
    • (2013) J. BoneMiner. Res , vol.28 , pp. 2122-2135
    • Xia, W.-F.1    Jung, J.-U.2    Shun, C.3    Xiong, S.4    Xiong, L.5    Shi, X.-M.6
  • 66
    • 84868117008 scopus 로고    scopus 로고
    • Adipokines in psoriatic arthritis patients: The correlations with osteoclast precursors and bone erosions
    • doi:10.1371/journal.pone. 0046740
    • Xue, Y., Jiang, L., Cheng, Q., Chen, H., Yu, Y., Lin, Y., et al. (2012). Adipokines in psoriatic arthritis patients: the correlations with osteoclast precursors and bone erosions. PLoS ONE 7:e46740. doi:10.1371/journal.pone. 0046740
    • (2012) PLoS ONE , vol.7
    • Xue, Y.1    Jiang, L.2    Cheng, Q.3    Chen, H.4    Yu, Y.5    Lin, Y.6
  • 67
    • 78651292213 scopus 로고    scopus 로고
    • Curcumin improves bone microarchitecture and enhances mineral density in APP/PS1 transgenic mice
    • doi:10.1016/j.phymed. 2010.05.011
    • Yang, M.-W., Wang, T.-H., Yan, P.-P., Chu, L.-W., Yu, J., Gao, Z.-D., et al. (2011). Curcumin improves bone microarchitecture and enhances mineral density in APP/PS1 transgenic mice. Phytomedicine 18, 205-213. doi:10.1016/j.phymed. 2010.05.011
    • (2011) Phytomedicine , vol.18 , pp. 205-213
    • Yang, M.-W.1    Wang, T.-H.2    Yan, P.-P.3    Chu, L.-W.4    Yu, J.5    Gao, Z.-D.6
  • 68
    • 58849093595 scopus 로고    scopus 로고
    • Whole-body vibration effects on bone before and after hind-limb unloading in rats
    • doi:10.3357/ASEM.2368.2009
    • Yang, P., Jia, B., Ding, C., Wang, Z., Qian, A., and Shang, P. (2009). Whole-body vibration effects on bone before and after hind-limb unloading in rats. Aviat. Space Environ. Med. 80, 88-93. doi:10.3357/ASEM.2368.2009
    • (2009) Aviat. Space Environ. Med , vol.80 , pp. 88-93
    • Yang, P.1    Jia, B.2    Ding, C.3    Wang, Z.4    Qian, A.5    Shang, P.6
  • 69
    • 0032584208 scopus 로고    scopus 로고
    • Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
    • doi:10.1073/pnas. 95.7.3597
    • Yasuda, H., Shima, N., Nakagawa, N., Yamaguchi, K., Kinosaki, M., Mochizuki, S., et al. (1998). Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc. Natl.Acad. Sci. U.S.A. 95,3597-3602. doi:10.1073/pnas. 95.7.3597
    • (1998) Proc. Natl.Acad. Sci. U.S.A , vol.95 , pp. 3597-3602
    • Yasuda, H.1    Shima, N.2    Nakagawa, N.3    Yamaguchi, K.4    Kinosaki, M.5    Mochizuki, S.6
  • 70
    • 23844435985 scopus 로고    scopus 로고
    • Epidemiology of hip fracture in Japan: Incidence and risk factors
    • doi:10.1007/BF03026328
    • Yoshimura, N., Suzuki, T., Hosoi, T., and Orimo, H. (2005). Epidemiology of hip fracture in Japan: incidence and risk factors. J. Bone Miner. Res. 23(Suppl.), 78-80. doi:10.1007/BF03026328
    • (2005) J. Bone Miner. Res , vol.23 , Issue.SUPPL. , pp. 78-80
    • Yoshimura, N.1    Suzuki, T.2    Hosoi, T.3    Orimo, H.4
  • 71
    • 79955668093 scopus 로고    scopus 로고
    • Association between bone mineral density and the risk of Alzheimer's disease
    • doi:10.3233/JAD-2010-101467
    • Zhou, R., Deng, J., Zhang, M., Zhou, H.-D., and Wang, Y.-J. (2011). Association between bone mineral density and the risk of Alzheimer's disease. J. Alzheimers Dis. 24, 101-108. doi:10.3233/JAD-2010-101467
    • (2011) J. Alzheimers Dis , vol.24 , pp. 101-108
    • Zhou, R.1    Deng, J.2    Zhang, M.3    Zhou, H.-D.4    Wang, Y.-J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.