Green tea polyphenols improve bone microarchitecture in high-fat-diet-induced obese female rats through suppressing bone formation and erosion

Journal of Medicinal Food

Volumn 16, Issue 5, 2013, Pages 421-427

  Shen, Chwan Li ^a,b   Chyu, Ming Chien ^a   Cao, Jay J ^c   Yeh, James K ^d  

^a TEXAS TECH UNIVERSITY   (United States)

^b TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c GRAND FORKS HUMAN NUTRITION RESEARCH CENTER   (United States)

^d WINTHROP UNIVERSITY HOSPITAL   (United States)

Author keywords

bone histomorphometry; green tea; high fat; micro CT; obesity; rat

Indexed keywords

GREEN TEA POLYPHENOL; POLYPHENOL DERIVATIVE; UNCLASSIFIED DRUG;

ADD ON THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE MASS; BONE MINERALIZATION; BONE STRUCTURE; BONE TURNOVER; CONTROLLED STUDY; CORTICAL BONE; DIET SUPPLEMENTATION; DRUG EFFECT; DRUG EFFICACY; FEMALE; FEMUR; LIPID DIET; LUMBAR SPINE; NONHUMAN; OBESITY; OSSIFICATION; PRIORITY JOURNAL; RAT; TEA; THICKNESS; TIBIA; TIBIA SHAFT; TRABECULAR BONE;

ANIMALS; BONE AND BONES; BONE DENSITY; CAMELLIA SINENSIS; DIET, HIGH-FAT; DOWN-REGULATION; FEMALE; OBESITY; OSTEOGENESIS; PLANT PREPARATIONS; POLYPHENOLS; RATS; RATS, SPRAGUE-DAWLEY; TEA;

EID: 84877856832     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2012.0199     Document Type: Article

References (27)

1. Rosen CJ, Bouxsein ML: Mechanisms of disease: is osteoporosis the obesity of bone? Nat Clin Pract Rheumatol 2006;2:35-43.
2. Reid IR: Relationships between fat and bone. Osteoporos Int 2008;19:595-606.
3. Zhao LJ, Jiang H, Papasian CJ, Maulik D, Dress B, Hamilton J, Deng HW: Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis. J Bone Miner Res 2008;23:17-29.
4. Duque G: Bone and fat connection in aging bone. Curr Opin Rheumatol 2008;20:429-434.
5. Gimble JM, Nuttall ME: The relationship between adipose tissue and bone metabolism. Clin Biochem 2012;45:874-879.
6. Zaidi M, Buettner C, Sun L, Iqbal J: Minireview: the link between fat and bone: does mass beget mass? Endocrinology 2012;153:2070-2075.
7. Cao JJ, Gregoire BR, Gao H: High-fat diet decreases cancellous bone mass but has no effect on cortical bone mass in the tibia in mice. Bone 2009;44:1097-1104.
8. Cao JJ, Sun L, Gao H: Diet-induced obesity alters bone remodeling leading to decreased femoral trabecular bone mass in mice. Ann NY Acad Sci 2010;1192:292-297.
9. Ionova-Martin SS, Do SH, Barth HD, Szadkowska M, Porter AE, Ager JW 3rd, Ager JW Jr, Alliston T, Vaisse C, Ritchie RO: Reduced size-independent mechanical properties of cortical bone in high-fat diet-induced obesity. Bone 2010;46:217-225.
10. Ionova-Martin SS, Wade JM, Tang S, Shahnazari M, Ager JW 3rd, Lane NE, Yao W, Alliston T, Vaisse C, Ritchie RO: Changes in cortical bone response to high-fat diet from adolescence to adulthood in mice. Osteoporos Int 2011;22:2283-2293.
11. Lorincz C, Reimer RA, Boyd SK, Zernicke RF: High-fat, sucrose diet impairs geometrical and mechanical properties of cortical bone in mice. Br J Nutr 2010;103:1302-1308.
12. Chen JR, Lazarenko OP, Wu X, Tong Y, Blackburn ML, Shankar K, Badger TM, Ronis MJ: Obesity reduces bone density associated with activation of PPARc and suppression of Wnt/b-ca-tenin in rapidly growing male rats. PLoS One 2010;5:e13704.
13. Shen CL, Yeh JK, Cao JJ, Chyu MC, Wang JS: Green tea and bone health: evidence from laboratory studies. Pharmacol Res 2011;64:155-161.
14. Shen CL, Yeh JK, Stoecker BJ, Chyu MC, Wang JS: Green tea polyphenols mitigate deterioration of bone microarchitecture in middle-aged female rats. Bone 2009;44:684-690.
15. Shen CL, Yeh JK, Cao JJ, Tatum OL, Dagda RY, Wang JS: Green tea polyphenols mitigate bone loss of female rats in a chronic inflammation-induced bone loss model. J Nutr Biochem 2010;21:968-974.
16. Shen CL, Yeh JK, Samathanam C, Cao JJ, Stoecker BJ, Dagda RY, Chyu MC, Dunn DM, Wang JS: Green tea polyphenols attenuate deterioration of bone microarchitecture in female rats with systemic chronic inflammation. Osteoporos Int 2010;22:327-337.
17. Shen CL, Cao JJ, Dagda RY, Tenner TE Jr, Chyu MC, Yeh JK: Supplementation with green tea polyphenols improves bone microstructure and quality in aged, orchidectomized rats. Calcif Tissue Int 2011;88:455-463.
18. Shen CL, Cao JJ, Dagda RY, Chanjaplammootil S, Lu C, Chyu MC, Gao W, Wang JS, Yeh JK: Green tea polyphenols favors body composition and improves bond quality in long-term high-fat-diet-induced obese rats. Nutr Res 2012;32:448-457.
19. Parfitt AM, Drezner MJ, Glorieux FH, Kanis JA, Malluche H, Meunier PJ: Bone histomorphometry: standardization of nomenclature, symbols and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 1987;2:595-610.
20. Iwamoto J, Matsumoto H, Takeda T, Sato Y, Liu X, Yeh JK: Effects of vitamin K2 and residronate on bone formation and resorption, osteocyte lacunar system, and porosity the cortical bone of glucocorticoid-treated rats. Calcif Tissue Int 2008;83:121-128.
21. Patsch JM, Kiefer FW, Varga P, Pail P, Rauner M, Stupphann D, Resch H, Moser D, Zysset PK, Stulnig TM, Pietschmann P: Increased bone resorption and impaired bone microarchitecture in short-term and extended high-fat diet-induced obesity. Metabolism 2011;60:243-249.
22. Kamon M, Zhao R, Sakamoto K: Green tea polyphenol (-)-epigallocatechin gallate suppressed the differentiation of murine osteoblastic MC3T3-E1 cells. Cell Biol Int 2009;34: 109-116.
23. Lee JH, Jin H, Shim HE, Kim HN, Ha H, Lee ZH: Epigalloca-techin-3-gallate inhibits osteoclastogenesis by down-regulating c-Fos expression and suppressing the nuclear factor-kappaB signal. Mol Pharmacol 2010;77:17-25.
24. Lin RW, Chen CH, Wang YH, Ho ML, Hung SH, Chen IS, Wang GJ: (-)-Epigallocatechin gallate inhibition of osteoclastic differentiation via NF-kappaB. Biochem Biophys Res Commun 2009;379:1033-1037.
25. Yun JH, Pang EK, Kim CS, Yoo YJ, Cho KS, Chai JK, Kim CK, Choi SH: Inhibitory effects of green tea polyphenol (-)-epi-gallocatechin gallate on the expression of matrix metalloprotei-nase-9 and on the formation of osteoclasts. J Periodontal Res 2004;39:300-307.
26. Iwaniec UT, Turner RT, Koo SI, Kaur R, Ho E, Wong CP, Bruno RS: Consumption of green tea extract results in osteopenia in growing male mice. J Nutr 2009;139:1914-1919.
27. Shen CL, Wang P, Guerrieri J, Yeh JK, Wang JS: Protective effect of green tea polyphenols on bone loss in middle-aged female rats. Osteoporos Int 2008;19:979-990.