Low body mass index is an important risk factor for low bone mass and increased bone loss in early postmenopausal women

Journal of Bone and Mineral Research

Volumn 14, Issue 9, 1999, Pages 1622-1627

  Ravn, Pernille ^a   Cizza, G ^b   Bjarnason, N H ^a   Thompson, D ^b   Daley, M ^b   Wasnich, R D ^c   McClung, M ^d   Hosking, D ^e   Yates, A J ^b   Christiansen, C ^a  

^a CENTER FOR CLINICAL AND BASIC RESEARCH   (Denmark)

^b MERCK RESEARCH LABORATORIES   (United States)

^c Hawaii Osteoporosis Center   (United States)

^d OREGON OSTEOPOROSIS CENTER   (United States)

^e NOTTINGHAM CITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; OSTEOCALCIN; PROCOLLAGEN N PROTEINASE;

ADULT; ARTICLE; BODY MASS; BONE DENSITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; ORAL DRUG ADMINISTRATION; POSTMENOPAUSE OSTEOPOROSIS; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR;

ALENDRONATE; BODY MASS INDEX; BONE DENSITY; COLLAGEN; COLLAGEN TYPE I; FEMALE; HUMANS; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; PEPTIDES; RISK FACTORS; THINNESS;

EID: 0032881714     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1999.14.9.1622     Document Type: Article

References (22)

1. Jones G, Nguyen T, Sambrook PN, Kelly PJ, Gilbert C, Eisman JA 1994 Symptomatic fracture incidence in elderly men and women: Dubbo Osteoporosis Epidemiol Study (DOES). Osteoporos Int 4:277-282.
2. Melton LJ III, Lane AW, Cooper C, Eastell R, O'Fallon WM, Riggs BL 1993 Prevalence and incidence of vertebral deformities. Osteoporos Int 3:113-119.
3. Riggs BL, Melton LJ III 1992 The prevention and treatment of osteoporosis. N Engl J Med 327:620-627.
4. Cummings SR, Rubin SM, Black D 1990 The future of hip fractures in the United States: Numbers, costs, and potential effect of postmenopausal estrogen. Clin Orthop 252:163-166.
5. Stevenson JC, Lees B, Devenport M, Cust MP, Ganger KF 1989 Determinants of bone density in normal women: Risk factors for future osteoporosis? Br Med J 298:924-928.
6. Dawson-Hughes B, Shipp C, Sadowski L, Dallal G 1987 Bone density of the radius, spine, and hip in relation to percent of ideal body weight in postmenopausal women. Calcif Tissue Int 40:310-314.
7. Lindsay R, Cosman F, Herrington BS, Himmelstein S 1992 Bone mass and body composition in normal women. J Bone Miner Res 7:55-63.
8. Ribot C, Tremollieres F, Pouilles JM, Bonneu M, Germain F, Louvet JP 1988 Obesity and postmenopausal bone loss: The influence of obesity on vertebral density and bone turnover in postmenopausal women. Bone 8:327-331.
9. Edelstein SL, Barrett-Connor E 1993 Relation between body size and bone mineral density in elderly men and women. Am J Epidemiol 138:160-169.
10. Hassager C, Christiansen C 1989 Influence of soft tissue body composition on bone mass and metabolism. Bone 10:415-419.
11. Christiansen C, Riis BJ, Rødbro P 1987 Prediction of rapid bone loss in postmenopausal women. Lancet 1:1105-1108.
12. Hosking D, Chilvers CED, Christiansen C, Ravn P, Wasnich R, Ross P, McClung M, Balske A, Thompson D, Daley M, Yates AJ 1998 Prevention of bone loss wilh alendronate in postmenopausal women under 60 years of age. N Engl J Med 338:485-492.
13. Minisola S, Rosso R, Romagnoli E, D'Erasmo E, Manfredi G, Damiani C, De Antoni F, Mazzuoli G 1997 Serum osteocalcin and bone mineral density at various skeletal sites: A study performed with three different assays. J Lab Clin Med 129:422-429.
14. Hanson DA, Weis MAE, Bollen AM, Maslan SL, Singer FR, Eyre DR 1992 A specific immunoassay for monitoring human bone resorption: Quantitation of type 1 collagen cross-linked N-telopeptides in urine. J Bone Miner Res 7:1251-1258.
15. Ravn P, Overgaard K, Huang C, Ross PD, Green D, McClung M 1996 Comparison of bone densitometry of the phalanges, distal forearm and axial skeleton in early postmenopausal women participating in the EPIC study. Osteoporos Int 6:308-313.
16. Kanis JA, Melton LJ III, Christiansen C, Johnston CC, Khaltaev N 1994 The diagnosis of osteoporosis. J Bone Miner Res 9:1137-1141.
17. Hansen M, Overgaard K, Riis BJ, Christiansen C 1991 Role of peak bone mass and bone loss in postmenopausal osteoporosis: 12 year study. BMJ 303:961-964.
18. Fleisch H 1991 Bisphosphonates: Pharmacology and use in the treatment of tumour-induced hypercalcaemic and metastatic bone disease. Drugs 42:919-944.
19. Lin JH, Duggan DE, Chen IW, Ellsworth RL 1991 Physiological disposition of alendronate, a potent anti-osteolytic bisphosphonate, in laboratory animals. Drug Metab Dispos 19:926-932.
20. Gertz BJ, Holland SD, Kline WF, Matuszeswki BK, Freeman A, Quan H, Lasseter KC, Mucklow JC, Porras AG 1995 Studies of oral bioavailablity of alendronate. Clin Pharmacol Ther 58:288-298.
21. Gallagher JC, Goldgar D, Moy A 1987 Total bone calcium in normal women: Effect of age and menopause status. J Bone Miner Res 2:491-496.
22. Sambrook PN, Eisman JA, Furler SM, Pocock NA 1987 Computer modelling and analysis of cross-sectional bone density studies with respect to age and the menopause. J Bone Miner Res 2:109-114.