메뉴 건너뛰기




Volumn 55, Issue 8, 2014, Pages 4832-4841

Quantitative autofluorescence and cell density maps of the human retinal pigment epithelium

Author keywords

Autofluorescence; Cytoskeleton; Lipofuscin; Photoreceptor; Retinal pigment epithelium

Indexed keywords

AUTOFLUORESCENCE; CYTOSKELETON; LIPOFUSCIN; PHOTORECEPTOR; RETINAL PIGMENT EPITHELIUM;

EID: 84905690180     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.14-14802     Document Type: Article
Times cited : (178)

References (85)
  • 1
    • 0021752680 scopus 로고
    • Age-related macular degeneration and blindness due to neovascular maculopathy
    • Ferris FL, Fine SL, Hyman L. Age-related macular degeneration and blindness due to neovascular maculopathy. Arch Ophthalmol. 1984;102:1640-1642.
    • (1984) Arch Ophthalmol , vol.102 , pp. 1640-1642
    • Ferris, F.L.1    Fine, S.L.2    Hyman, L.3
  • 2
    • 0028839002 scopus 로고
    • The prevalence of age-related macuolpathy in the Rotterdam study
    • Vingerling JR, Dielemans I, Hofman A, et al. The prevalence of age-related macuolpathy in the Rotterdam study. Ophthalmology. 1995;102:205-210.
    • (1995) Ophthalmology , vol.102 , pp. 205-210
    • Vingerling, J.R.1    Dielemans, I.2    Hofman, A.3
  • 3
    • 11144354339 scopus 로고    scopus 로고
    • Prevalence of agerelated macular degeneration in the United States
    • Friedman DS, O'colmain BJ, Munoz B, et al. Prevalence of agerelated macular degeneration in the United States. Arch Ophthalmol. 2004;122:564-572.
    • (2004) Arch Ophthalmol , vol.122 , pp. 564-572
    • Friedman, D.S.1    O'Colmain, B.J.2    Munoz, B.3
  • 5
    • 21244451958 scopus 로고    scopus 로고
    • The retinal pigment epithelium in visual function
    • Strauss O. The retinal pigment epithelium in visual function. Physiol Rev. 2005;85:845-881.
    • (2005) Physiol Rev , vol.85 , pp. 845-881
    • Strauss, O.1
  • 6
    • 53449084910 scopus 로고    scopus 로고
    • Control of chemokine gradients by the retinal pigment epithelium
    • Shi G, Maminishkis A, Banzon T, et al. Control of chemokine gradients by the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2008;49:4620-4630.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 4620-4630
    • Shi, G.1    Maminishkis, A.2    Banzon, T.3
  • 7
    • 59449093969 scopus 로고    scopus 로고
    • Lipoprotein particles of intraocular origin in human Bruch membrane: An unusual lipid profile
    • Wang L, Li CM, Rudolf M, et al. Lipoprotein particles of intraocular origin in human Bruch membrane: an unusual lipid profile. Invest Ophthalmol Vis Sci. 2009;50:870-877.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 870-877
    • Wang, L.1    Li, C.M.2    Rudolf, M.3
  • 8
    • 0017843940 scopus 로고
    • Lipofuscin and melanin of human retinal pigment epithelium. Fluorescence, enzyme cytochemical, and ultrastructural studies
    • Feeney L. Lipofuscin and melanin of human retinal pigment epithelium. Fluorescence, enzyme cytochemical, and ultrastructural studies. Invest Ophthalmol Vis Sci. 1978;17:583-600.
    • (1978) Invest Ophthalmol Vis Sci , vol.17 , pp. 583-600
    • Feeney, L.1
  • 9
    • 0021323978 scopus 로고
    • Aging human RPE: Morphometric analysis of macular, equatorial, and peripheral cells
    • Feeney-Burns L, Hilderbrand ES, Eldridge S. Aging human RPE: morphometric analysis of macular, equatorial, and peripheral cells. Invest Ophthalmol Vis Sci. 1984;25:195-200.
    • (1984) Invest Ophthalmol Vis Sci , vol.25 , pp. 195-200
    • Feeney-Burns, L.1    Hilderbrand, E.S.2    Eldridge, S.3
  • 10
    • 0022585542 scopus 로고
    • Retinal pigment epithelial lipofuscin and melanin and choroidal melanin in human eyes
    • Weiter JJ, Delori FC, Wing GL, Fitch KA. Retinal pigment epithelial lipofuscin and melanin and choroidal melanin in human eyes. Invest Ophthalmol Vis Sci. 1986;27:145-152.
    • (1986) Invest Ophthalmol Vis Sci , vol.27 , pp. 145-152
    • Weiter, J.J.1    Delori, F.C.2    Wing, G.L.3    Fitch, K.A.4
  • 11
    • 0020323939 scopus 로고
    • Lipofuscin: Resolution of discrepant fluorescence data
    • Eldred G, Miller GV, Stark WS, Feeney-Burns L. Lipofuscin: resolution of discrepant fluorescence data. Science. 1982;216: 757-759.
    • (1982) Science , vol.216 , pp. 757-759
    • Eldred, G.1    Miller, G.V.2    Stark, W.S.3    Feeney-Burns, L.4
  • 12
    • 47849092882 scopus 로고    scopus 로고
    • Retinal pigment epithelium lipofuscin proteomics
    • Ng KP, Gugiu B, Renganathan K, et al. Retinal pigment epithelium lipofuscin proteomics. Mol Cell Proteomics. 2008; 7:1397-1405.
    • (2008) Mol Cell Proteomics , vol.7 , pp. 1397-1405
    • Ng, K.P.1    Gugiu, B.2    Renganathan, K.3
  • 15
    • 0024378477 scopus 로고
    • Cell loss in the aging retina. Relationship to lipofuscin accumulation and macular degeneration
    • Dorey CK, Wu G, Ebenstein D, Garsd A, Weiter JJ. Cell loss in the aging retina. Relationship to lipofuscin accumulation and macular degeneration. Invest Ophthalmol Vis Sci. 1989;30: 1691-1699.
    • (1989) Invest Ophthalmol Vis Sci , vol.30 , pp. 1691-1699
    • Dorey, C.K.1    Wu, G.2    Ebenstein, D.3    Garsd, A.4    Weiter, J.J.5
  • 17
    • 0017897377 scopus 로고
    • The topography and age relationship of lipofuscin concentration in the retinal pigment epithelium
    • Wing GL, Blanchard GC, Weiter JJ. The topography and age relationship of lipofuscin concentration in the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1978;17:601-607.
    • (1978) Invest Ophthalmol Vis Sci , vol.17 , pp. 601-607
    • Wing, G.L.1    Blanchard, G.C.2    Weiter, J.J.3
  • 18
    • 0001897347 scopus 로고
    • Topography of the layer of rods and cones in the human retina
    • Østerberg GA. Topography of the layer of rods and cones in the human retina. Acta Ophthalmol. 1935;13:1-103.
    • (1935) Acta Ophthalmol , vol.13 , pp. 1-103
    • Østerberg, G.A.1
  • 20
    • 0022342758 scopus 로고
    • Repigmentation of human retinal pigment epithelial cells in vitro
    • Boulton M, Marshall J. Repigmentation of human retinal pigment epithelial cells in vitro. Exp Eye Res. 1985;41:209-218.
    • (1985) Exp Eye Res , vol.41 , pp. 209-218
    • Boulton, M.1    Marshall, J.2
  • 21
    • 0030931137 scopus 로고    scopus 로고
    • Development and aging of cell topography in the human retinal pigment epithelium
    • Harman AM, Fleming PA, Hoskins RV, Moore SR. Development and aging of cell topography in the human retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1997;38:2016-2026.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 2016-2026
    • Harman, A.M.1    Fleming, P.A.2    Hoskins, R.V.3    Moore, S.R.4
  • 22
    • 0036785896 scopus 로고    scopus 로고
    • Age-related changes in human RPE cell density and apoptosis proportion in situ
    • Del Priore LV, Kuo YH, Tezel TH. Age-related changes in human RPE cell density and apoptosis proportion in situ. Invest Ophthalmol Vis Sci. 2002;43:3312-3318.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 3312-3318
    • Del, P.L.V.1    Kuo, Y.H.2    Tezel, T.H.3
  • 23
    • 0026502611 scopus 로고
    • Aging of the human retina. Differential loss of neurons and retinal pigment epithelial cells
    • Gao H, Hollyfield JG. Aging of the human retina. Differential loss of neurons and retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1992;33:1-17.
    • (1992) Invest Ophthalmol Vis Sci , vol.33 , pp. 1-17
    • Gao, H.1    Hollyfield, J.G.2
  • 24
    • 0027368450 scopus 로고
    • Aging of the human photoreceptor mosaic: Evidence for selective vulnerability of rods in central retina
    • Curcio CA, Millican CL, Allen KA, Kalina RE. Aging of the human photoreceptor mosaic: evidence for selective vulnerability of rods in central retina. Invest Ophthalmol Vis Sci. 1993;34:3278-3296.
    • (1993) Invest Ophthalmol Vis Sci , vol.34 , pp. 3278-3296
    • Curcio, C.A.1    Millican, C.L.2    Allen, K.A.3    Kalina, R.E.4
  • 25
    • 0036594136 scopus 로고    scopus 로고
    • Photoreceptor degeneration and dysfunction in aging and age-related maculopathy
    • Jackson GR, Owsley C, Curcio CA. Photoreceptor degeneration and dysfunction in aging and age-related maculopathy. Ageing Res Rev. 2002;1:381-396.
    • (2002) Ageing Res Rev , vol.1 , pp. 381-396
    • Jackson, G.R.1    Owsley, C.2    Curcio, C.A.3
  • 26
    • 0031806880 scopus 로고    scopus 로고
    • The Alabama Age- Related Macular Degeneration Grading System for donor eyes
    • Curcio CA, Medeiros NE, Millican CL. The Alabama Age- Related Macular Degeneration Grading System for donor eyes. Invest Ophthalmol Vis Sci. 1998;39:1085-1096.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 1085-1096
    • Curcio, C.A.1    Medeiros, N.E.2    Millican, C.L.3
  • 27
    • 78049431560 scopus 로고    scopus 로고
    • Mass spectrometry provides accurate and sensitive quantitation of A2E
    • Gutierrez DB, Blakeley L, Goletz PW, et al. Mass spectrometry provides accurate and sensitive quantitation of A2E. Photochem Photobiol Sci. 2010;9:1513-1519.
    • (2010) Photochem Photobiol Sci , vol.9 , pp. 1513-1519
    • Gutierrez, D.B.1    Blakeley, L.2    Goletz, P.W.3
  • 28
    • 0024093159 scopus 로고
    • The cytoskeletal elements of human retinal pigment epithelium: In vitro and in vivo
    • McKechnie NM, Boulton M, Robey HL, Savage FJ, Grierson I. The cytoskeletal elements of human retinal pigment epithelium: in vitro and in vivo. J Cell Sci. 1988;91:303-312.
    • (1988) J Cell Sci , vol.91 , pp. 303-312
    • McKechnie, N.M.1    Boulton, M.2    Robey, H.L.3    Savage, F.J.4    Grierson, I.5
  • 30
    • 0034940622 scopus 로고    scopus 로고
    • Age-related accumulation and spatial distribution of lipofuscin in RPE of normal subjects
    • Delori FC, Goger DG, Dorey CK. Age-related accumulation and spatial distribution of lipofuscin in RPE of normal subjects. Invest Ophthalmol Vis Sci. 2001;42:1855-1866.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 1855-1866
    • Delori, F.C.1    Goger, D.G.2    Dorey, C.K.3
  • 31
    • 0033793224 scopus 로고    scopus 로고
    • Voronoi tessellation to study the numerical density and the spatial distribution of neurones
    • Duyckaerts C, Godefroy G. Voronoi tessellation to study the numerical density and the spatial distribution of neurones. J Chem Neuroanat. 2000;20:83-92.
    • (2000) J Chem Neuroanat , vol.20 , pp. 83-92
    • Duyckaerts, C.1    Godefroy, G.2
  • 32
    • 79955630007 scopus 로고    scopus 로고
    • High-resolution imaging of the photoreceptor jayer in epiretinal membrane using adaptive optics scanning laser ophthalmoscopy
    • Ooto S, Hangai M, Takayama K, et al. High-resolution imaging of the photoreceptor jayer in epiretinal membrane using adaptive optics scanning laser ophthalmoscopy. Ophthalmology. 2011;118:873-881.
    • (2011) Ophthalmology , vol.118 , pp. 873-881
    • Ooto, S.1    Hangai, M.2    Takayama, K.3
  • 33
    • 62649152376 scopus 로고    scopus 로고
    • In vivo autofluorescence imaging of the human and macaque retinal pigment epithelial cell mosaic
    • Morgan JIW, Dubra A, Wolfe R, Merigan WH, Williams DR. In vivo autofluorescence imaging of the human and macaque retinal pigment epithelial cell mosaic. Invest Ophthalmol Vis Sci. 2009;50:1350-1359.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 1350-1359
    • Morgan, J.I.W.1    Dubra, A.2    Wolfe, R.3    Merigan, W.H.4    Williams, D.R.5
  • 34
    • 84862833106 scopus 로고    scopus 로고
    • Quantitative measurements of autofluorescence with the scanning laser ophthalmoscope
    • Delori F, Greenberg JP, Woods RL, et al. Quantitative measurements of autofluorescence with the scanning laser ophthalmoscope. Invest Ophthalmol Vis Sci. 2011;52:9379-9390.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 9379-9390
    • Delori, F.1    Greenberg, J.P.2    Woods, R.L.3
  • 36
    • 0037441919 scopus 로고    scopus 로고
    • Statistical analysis of correlated data using generalized estimating equations: An orientation
    • Hanley JA, Negassa A, Forrester JE. Statistical analysis of correlated data using generalized estimating equations: an orientation. Am J Epidemiol. 2003;157:364-375.
    • (2003) Am J Epidemiol , vol.157 , pp. 364-375
    • Hanley, J.A.1    Negassa, A.2    Forrester, J.E.3
  • 37
    • 0025011140 scopus 로고
    • Topography of ganglion cells in human retina
    • Curcio CA, Allen KA. Topography of ganglion cells in human retina. J Comp Neurol. 1990;300:5-25.
    • (1990) J Comp Neurol , vol.300 , pp. 5-25
    • Curcio, C.A.1    Allen, K.A.2
  • 38
    • 0030063374 scopus 로고    scopus 로고
    • Retinal pigment epithelial cell count, distribution, and correlations in normal human eyes
    • Panda-Jonas S, Jonas JB, Jakobczyk-Zmija M. Retinal pigment epithelial cell count, distribution, and correlations in normal human eyes. Am J Ophthalmol. 1996;121:181-189.
    • (1996) Am J Ophthalmol , vol.121 , pp. 181-189
    • Panda-Jonas, S.1    Jonas, J.B.2    Jakobczyk-Zmija, M.3
  • 39
    • 0014316848 scopus 로고
    • The retinal pigment epithelium. 3. Growth and development
    • Ts'o MO, Friedman E. The retinal pigment epithelium. 3. Growth and development. Arch Ophthalmol. 1968;80:214-216.
    • (1968) Arch Ophthalmol , vol.80 , pp. 214-216
    • Ts'O, M.O.1    Friedman, E.2
  • 40
    • 0014477738 scopus 로고
    • Development of the human retinal pigment epithelium and the posterior segment
    • Streeten BW. Development of the human retinal pigment epithelium and the posterior segment. Arch Ophthalmol. 1969;81:383-394.
    • (1969) Arch Ophthalmol , vol.81 , pp. 383-394
    • Streeten, B.W.1
  • 41
    • 0027534638 scopus 로고
    • Morphometric analysis of human retinal pigment epithelium: Correlation with age and location
    • Watzke RC, Soldevilla JD, Trune DR. Morphometric analysis of human retinal pigment epithelium: correlation with age and location. Curr Eye Res. 1993;12:133-142.
    • (1993) Curr Eye Res , vol.12 , pp. 133-142
    • Watzke, R.C.1    Soldevilla, J.D.2    Trune, D.R.3
  • 42
    • 84905698800 scopus 로고    scopus 로고
    • Mosaicism of the retinal pigment epitheliums
    • Burke JM, Hjelmeland LM. Mosaicism of the retinal pigment epitheliums. Mol Interv. 2005;5:9.
    • (2005) Mol Interv , vol.5 , pp. 9
    • Burke, J.M.1    Hjelmeland, L.M.2
  • 43
    • 0011922008 scopus 로고
    • The geometry of growth and cell division in epithelial mosaics
    • Lewis FT. The geometry of growth and cell division in epithelial mosaics. Am J Bot. 1943;30:766-776.
    • (1943) Am J Bot , vol.30 , pp. 766-776
    • Lewis, F.T.1
  • 44
    • 84882781321 scopus 로고    scopus 로고
    • Lack of correlation between the spatial distribution of A2E and lipofuscin fluorescence in the human retinal pigment epithelium
    • Ablonczy Z, Higbee D, Anderson DM, et al. Lack of correlation between the spatial distribution of A2E and lipofuscin fluorescence in the human retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2013;54:5535-5542.
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , pp. 5535-5542
    • Ablonczy, Z.1    Higbee, D.2    Anderson, D.M.3
  • 46
    • 0022455524 scopus 로고
    • Melanin concentration in normal human retinal pigment epithelium. Regional variation and agerelated reduction
    • Schmidt SY, Peisch RD. Melanin concentration in normal human retinal pigment epithelium. Regional variation and agerelated reduction. Invest Ophthalmol Vis Sci. 1986;27:1063- 1067.
    • (1986) Invest Ophthalmol Vis Sci , vol.27 , pp. 1063-1067
    • Schmidt, S.Y.1    Peisch, R.D.2
  • 47
    • 70350422838 scopus 로고    scopus 로고
    • Aging, Rudolf M. age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins
    • Curcio CA, Johnson M, Huang JD, Aging, Rudolf M. age-related macular degeneration, and the response-to-retention of apolipoprotein B-containing lipoproteins. Prog Retin Eye Res. 2009;28:393-422.
    • (2009) Prog Retin Eye Res , vol.28 , pp. 393-422
    • Curcio, C.A.1    Johnson, M.2    Huang, J.D.3
  • 48
    • 84855926087 scopus 로고    scopus 로고
    • Passage of lowdensity lipoproteins through Bruch's membrane and choroid
    • Cankova Z, Huang JD, Kruth HS, Johnson M. Passage of lowdensity lipoproteins through Bruch's membrane and choroid. Exp Eye Res. 2011;93:947-955.
    • (2011) Exp Eye Res , vol.93 , pp. 947-955
    • Cankova, Z.1    Huang, J.D.2    Kruth, H.S.3    Johnson, M.4
  • 49
    • 0033924382 scopus 로고    scopus 로고
    • Spare the rods, save the cones in aging and age-related maculopathy
    • Curcio CA, Owsley C, Jackson GR. Spare the rods, save the cones in aging and age-related maculopathy. Invest Ophthalmol Vis Sci. 2000;41:2015-2018.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 2015-2018
    • Curcio, C.A.1    Owsley, C.2    Jackson, G.R.3
  • 50
    • 84887838450 scopus 로고    scopus 로고
    • Altered gene expression in dry age-related macular degeneration suggests early loss of choroidal endothelial cells
    • Whitmore SS, Braun TA, Skeie JM, et al. Altered gene expression in dry age-related macular degeneration suggests early loss of choroidal endothelial cells. Mol Vis. 2013;19: 2274-2297.
    • (2013) Mol Vis , vol.19 , pp. 2274-2297
    • Whitmore, S.S.1    Braun, T.A.2    Skeie, J.M.3
  • 52
    • 0027982045 scopus 로고
    • Histopathology and immunocytochemistry of the neurosensory retina in fundus flavimaculatus
    • Birnbach CD, Jarvelainen M, Possin DE, Milam AH. Histopathology and immunocytochemistry of the neurosensory retina in fundus flavimaculatus. Ophthalmology. 1994;101:1211-1219.
    • (1994) Ophthalmology , vol.101 , pp. 1211-1219
    • Birnbach, C.D.1    Jarvelainen, M.2    Possin, D.E.3    Milam, A.H.4
  • 53
    • 0039688932 scopus 로고
    • The effect of cell division on the shape and size of hexagonal cells
    • Lewis FT. The effect of cell division on the shape and size of hexagonal cells. Anat Rec. 1926;33:331-355.
    • (1926) Anat Rec , vol.33 , pp. 331-355
    • Lewis, F.T.1
  • 54
    • 0018621985 scopus 로고
    • Mitotic activity of the pigment epithelium during embryonic and postembryonic development
    • Kaldarar-Pedotti S. Mitotic activity of the pigment epithelium during embryonic and postembryonic development. Adv Ophthalmol. 1979;39:37-58.
    • (1979) Adv Ophthalmol , vol.39 , pp. 37-58
    • Kaldarar-Pedotti, S.1
  • 56
    • 79961005068 scopus 로고    scopus 로고
    • Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration
    • Ding JD, Johnson LV, Herrmann R, et al. Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration. Proc Natl Acad Sci U S A. 2011;108:E279-E287.
    • (2011) Proc Natl Acad Sci U S A , vol.108
    • Ding, J.D.1    Johnson, L.V.2    Herrmann, R.3
  • 57
    • 0036119813 scopus 로고    scopus 로고
    • Potential role of retinal pigment epithelial lipofuscin accumulation in age-related macular degeneration
    • Katz ML. Potential role of retinal pigment epithelial lipofuscin accumulation in age-related macular degeneration. Arch Gerontol Geriatr. 2002;34:359-370.
    • (2002) Arch Gerontol Geriatr , vol.34 , pp. 359-370
    • Katz, M.L.1
  • 59
    • 0036124957 scopus 로고    scopus 로고
    • What is lipofuscin? Defining characteristics and differentiation from other autofluorescent lysosomal storage bodies
    • Katz ML, Robison WG. What is lipofuscin? Defining characteristics and differentiation from other autofluorescent lysosomal storage bodies. Arch Gerontol Geriatr. 2002;34:169-184.
    • (2002) Arch Gerontol Geriatr , vol.34 , pp. 169-184
    • Katz, M.L.1    Robison, W.G.2
  • 60
    • 0027234987 scopus 로고
    • Age pigment structure
    • Eldred G. Age pigment structure. Nature. 1993;364:396.
    • (1993) Nature , vol.364 , pp. 396
    • Eldred, G.1
  • 61
    • 77949503904 scopus 로고    scopus 로고
    • Phospholipid meets alltrans- retinal: The making of RPE bisretinoids
    • Sparrow JR, Wu Y, Kim CY, Zhou J. Phospholipid meets alltrans- retinal: the making of RPE bisretinoids. J Lipid Res. 2010; 51:247-261.
    • (2010) J Lipid Res , vol.51 , pp. 247-261
    • Sparrow, J.R.1    Wu, Y.2    Kim, C.Y.3    Zhou, J.4
  • 63
    • 0035069027 scopus 로고    scopus 로고
    • Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration
    • Holz FG, Bellman C, Staudt S, Schutt F, Volcker HE. Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2001;42:1051-1056.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 1051-1056
    • Holz, F.G.1    Bellman, C.2    Staudt, S.3    Schutt, F.4    Volcker, H.E.5
  • 64
    • 84864385517 scopus 로고    scopus 로고
    • Lipofuscin can be eliminated from the retinal pigment epithelium of monkeys
    • Julien S, Schraermeyer U. Lipofuscin can be eliminated from the retinal pigment epithelium of monkeys. Neurobiol Aging. 2012;33:2390-2397.
    • (2012) Neurobiol Aging , vol.33 , pp. 2390-2397
    • Julien, S.1    Schraermeyer, U.2
  • 66
    • 84855205404 scopus 로고    scopus 로고
    • Safety and effect on rod function of ACU-4429, a novel smallmolecule visual cycle modulator
    • Kubota R, Boman NL, David R, Mallikaarjun S, Patil S, Birch D. Safety and effect on rod function of ACU-4429, a novel smallmolecule visual cycle modulator. Retina. 2012;32:183-188.
    • (2012) Retina , vol.32 , pp. 183-188
    • Kubota, R.1    Boman, N.L.2    David, R.3    Mallikaarjun, S.4    Patil, S.5    Birch, D.6
  • 67
    • 84898047300 scopus 로고    scopus 로고
    • Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium
    • Nociari MM, Lehmann GL, Perez Bay AE, et al. Beta cyclodextrins bind, stabilize, and remove lipofuscin bisretinoids from retinal pigment epithelium. Proc Natl Acad Sci U S A. 2014;111:E1402-E1408.
    • (2014) Proc Natl Acad Sci U S A , vol.111
    • Nociari, M.M.1    Lehmann, G.L.2    Perez, B.A.E.3
  • 69
    • 78650806834 scopus 로고    scopus 로고
    • Blue-blocking IOLS vs. shortwavelength visible light: Hypothesis-based vs. evidence-based medical practice
    • Mainster MA, Turner PL. Blue-blocking IOLS vs. shortwavelength visible light: hypothesis-based vs. evidence-based medical practice. Ophthalmology. 2011;118:1-2.
    • (2011) Ophthalmology , vol.118 , pp. 1-2
    • Mainster, M.A.1    Turner, P.L.2
  • 70
    • 52249097846 scopus 로고    scopus 로고
    • New approach to evaluate retinal protection by intraocular lenses against age-related lipofuscin accumulation-mediated retinal phototoxicity
    • Carson D, Margrain TH, Patel A. New approach to evaluate retinal protection by intraocular lenses against age-related lipofuscin accumulation-mediated retinal phototoxicity. J Cataract Refract Surg. 2008;34:1785-1792.
    • (2008) J Cataract Refract Surg , vol.34 , pp. 1785-1792
    • Carson, D.1    Margrain, T.H.2    Patel, A.3
  • 71
    • 33745646365 scopus 로고    scopus 로고
    • Predictive value of fundus autofluorescence for development of geographic atrophy in age-related macular degeneration
    • Hwang JC, Chan JW, Chang S, Smith RT. Predictive value of fundus autofluorescence for development of geographic atrophy in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2006;47:2655-2661.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 2655-2661
    • Hwang, J.C.1    Chan, J.W.2    Chang, S.3    Smith, R.T.4
  • 72
    • 84875734739 scopus 로고    scopus 로고
    • Histologic basis of variations in retinal pigment epithelium autofluorescence in eyes with geographic atrophy
    • Rudolf M, Vogt SD, Curcio CA, et al. Histologic basis of variations in retinal pigment epithelium autofluorescence in eyes with geographic atrophy. Ophthalmology. 2013;120:821-828.
    • (2013) Ophthalmology , vol.120 , pp. 821-828
    • Rudolf, M.1    Vogt, S.D.2    Curcio, C.A.3
  • 73
    • 62349128260 scopus 로고    scopus 로고
    • Retinal carotenoids can attenuate formation of A2E in the retinal pigment epithelium
    • Bhosale P, Serban B, Bernstein PS. Retinal carotenoids can attenuate formation of A2E in the retinal pigment epithelium. Arch Biochem Biophys. 2009;483:175-181.
    • (2009) Arch Biochem Biophys , vol.483 , pp. 175-181
    • Bhosale, P.1    Serban, B.2    Bernstein, P.S.3
  • 75
    • 84880551919 scopus 로고    scopus 로고
    • Noncanonical autophagy promotes the visual cycle
    • Kim JY, Zhao H, Martinez J, et al. Noncanonical autophagy promotes the visual cycle. Cell. 2013;154:365-376.
    • (2013) Cell , vol.154 , pp. 365-376
    • Kim, J.Y.1    Zhao, H.2    Martinez, J.3
  • 76
    • 84860883878 scopus 로고    scopus 로고
    • DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88
    • Tarallo V, Hirano Y, Gelfand BD, et al. DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell. 2012;149:847-859.
    • (2012) Cell , vol.149 , pp. 847-859
    • Tarallo, V.1    Hirano, Y.2    Gelfand, B.D.3
  • 77
    • 84925545770 scopus 로고    scopus 로고
    • Cholesterol in the retina: The best is yet to come
    • Pikuleva IA, Curcio CA. Cholesterol in the retina: the best is yet to come. Prog Retin Eye Res. 2014;41C:64-89.
    • (2014) Prog Retin Eye Res , vol.41 C , pp. 64-89
    • Pikuleva, I.A.1    Curcio, C.A.2
  • 78
    • 84895070241 scopus 로고    scopus 로고
    • Assessing the cone photoreceptor mosaic in eyes with pseudodrusen and soft Drusen in vivo using adaptive optics imaging
    • Mrejen S, Sato T, Curcio CA, Spaide RF. Assessing the cone photoreceptor mosaic in eyes with pseudodrusen and soft Drusen in vivo using adaptive optics imaging. Ophthalmology. 2014;121:545-551.
    • (2014) Ophthalmology , vol.121 , pp. 545-551
    • Mrejen, S.1    Sato, T.2    Curcio, C.A.3    Spaide, R.F.4
  • 80
    • 84887196401 scopus 로고    scopus 로고
    • In vivo imaging of retinal pigment epithelium cells in age related macular degeneration
    • Rossi EA, Rangel-Fonseca P, Parkins K, et al. In vivo imaging of retinal pigment epithelium cells in age related macular degeneration. Biomed Opt Express. 2013;4:2527-2539.
    • (2013) Biomed Opt Express , vol.4 , pp. 2527-2539
    • Rossi, E.A.1    Rangel-Fonseca, P.2    Parkins, K.3
  • 81
    • 84883361410 scopus 로고    scopus 로고
    • In vivo dark-field imaging of the retinal pigment epithelium cell mosaic
    • Scoles D, Sulai YN, Dubra A. In vivo dark-field imaging of the retinal pigment epithelium cell mosaic. Biomed Opt Express. 2013;4:1710-1723.
    • (2013) Biomed Opt Express , vol.4 , pp. 1710-1723
    • Scoles, D.1    Sulai, Y.N.2    Dubra, A.3
  • 82
    • 80054860164 scopus 로고    scopus 로고
    • Recovery of macular pigment spectrum in vivo using hyperspectral image analysis
    • Fawzi AA, Lee N, Acton JH, Laine AF, Smith RT. Recovery of macular pigment spectrum in vivo using hyperspectral image analysis. J Biomed Opt. 2011;16:106008.
    • (2011) J Biomed Opt , vol.16 , pp. 106008
    • Fawzi, A.A.1    Lee, N.2    Acton, J.H.3    Laine, A.F.4    Smith, R.T.5
  • 84
    • 0029007962 scopus 로고
    • Age-related variation in the hydraulic conductivity of Bruch's membrane
    • Moore DJ, Hussain AA, Marshall J. Age-related variation in the hydraulic conductivity of Bruch's membrane. Invest Ophthalmol Vis Sci. 1995;36:1290-1297.
    • (1995) Invest Ophthalmol Vis Sci , vol.36 , pp. 1290-1297
    • Moore, D.J.1    Hussain, A.A.2    Marshall, J.3
  • 85
    • 84873411625 scopus 로고    scopus 로고
    • Subretinal drusenoid deposits in non-neovascular age-related macular degeneration: Morphology, prevalence, topography, and biogenesis model
    • Curcio CA, Messinger JD, Sloan KR, McGwin G, Medeiros NE, Spaide RF. Subretinal drusenoid deposits in non-neovascular age-related macular degeneration: morphology, prevalence, topography, and biogenesis model. Retina. 2013;33:265-276.
    • (2013) Retina , vol.33 , pp. 265-276
    • Curcio, C.A.1    Messinger, J.D.2    Sloan, K.R.3    McGwin, G.4    Medeiros, N.E.5    Spaide, R.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.