Netrin-1 induces MMP-12-dependent E-cadherin degradation via the distinct activation of PKCα and FAK/Fyn in promoting mesenchymal stem cell motility

Stem Cells and Development

Volumn 23, Issue 16, 2014, Pages 1870-1882

  Lee, Sei Jung ^a   Jung, Young Hyun ^a   Oh, Sang Yub ^a   Yong, Min Sik ^a   Ryu, Jung Min ^a   Han, Ho Jae ^a  

^a Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTININ 4; ALPHA6BETA4 INTEGRIN; COFILIN 1; COLLAGENASE 3; F ACTIN; FOCAL ADHESION KINASE; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; MATRILYSIN; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 16; MATRIX METALLOPROTEINASE 17; MATRIX METALLOPROTEINASE 19; MITOGEN ACTIVATED PROTEIN KINASE; NETRIN 1; NEUTROPHIL COLLAGENASE; PROFILIN; PROFILIN I; PROTEIN CDC42; PROTEIN KINASE C ALPHA; PROTEIN KINASE FYN; RAC1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; STROMELYSIN; STROMELYSIN 2; STROMELYSIN 3; UNCLASSIFIED DRUG; UVOMORULIN; CADHERIN; CDH1 PROTEIN, HUMAN; FOCAL ADHESION KINASE 1; FYN PROTEIN, HUMAN; MMP12 PROTEIN, HUMAN; NERVE GROWTH FACTOR; NETRIN-1; PRKCA PROTEIN, HUMAN; PTK2 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CELL MIGRATION; CELL MOTILITY; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UMBILICAL CORD BLOOD; CALCIUM SIGNALING; CELL CULTURE; CELL MOTION; CYTOSKELETON; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY;

CADHERINS; CALCIUM SIGNALING; CELL MOVEMENT; CELLS, CULTURED; CYTOSKELETON; ENZYME ACTIVATION; FOCAL ADHESION KINASE 1; HUMANS; MATRIX METALLOPROTEINASE 12; MESENCHYMAL STROMAL CELLS; NERVE GROWTH FACTORS; PROTEIN KINASE C-ALPHA; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-FYN; TUMOR SUPPRESSOR PROTEINS;

EID: 84905658928     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2013.0632     Document Type: Article

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