-
1
-
-
19544371373
-
Gene targeting in mice: Functional analysis of the mammalian genome for the twenty-first century
-
1:CAS:528:DC%2BD2MXkslSmsro%3D 15931173 10.1038/nrg1619
-
Capecchi MR (2005) Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century. Nat Rev Genet 6:507-512
-
(2005)
Nat Rev Genet
, vol.6
, pp. 507-512
-
-
Capecchi, M.R.1
-
2
-
-
78549267889
-
Targeted genome modification in mice using zinc-finger nucleases
-
1:CAS:528:DC%2BC3cXhsFOnt7rI 2954478 20628038 10.1534/genetics.110.117002
-
Carbery ID, Ji D, Harrington A, Brown V, Weinstein EJ, et al. (2010) Targeted genome modification in mice using zinc-finger nucleases. Genetics 186:451-459
-
(2010)
Genetics
, vol.186
, pp. 451-459
-
-
Carbery, I.D.1
Ji, D.2
Harrington, A.3
Brown, V.4
Weinstein, E.J.5
-
3
-
-
80052292973
-
High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases
-
1:CAS:528:DC%2BC3MXovFygs7w%3D 3617923 21765410 10.1038/nmeth.1653
-
Chen F, Pruett-Miller SM, Huang Y, Gjoka M, Duda K, et al. (2011) High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases. Nat Methods 8:753-755
-
(2011)
Nat Methods
, vol.8
, pp. 753-755
-
-
Chen, F.1
Pruett-Miller, S.M.2
Huang, Y.3
Gjoka, M.4
Duda, K.5
-
4
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
1:CAS:528:DC%2BC3sXit1ygtb8%3D 3795411 23287718 10.1126/science.1231143
-
Cong L, Ran FA, Cox D, Lin S, Barretto R, et al. (2013) Multiplex genome engineering using CRISPR/Cas systems. Science 339:819-823
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
-
5
-
-
0023630807
-
Targetted correction of a mutant HPRT gene in mouse embryonic stem cells
-
1:CAS:528:DyaL1cXltVGisw%3D%3D 3683574 10.1038/330576a0
-
Doetschman T, Gregg RG, Maeda N, Hooper ML, Melton DW, et al. (1987) Targetted correction of a mutant HPRT gene in mouse embryonic stem cells. Nature 330:576-578
-
(1987)
Nature
, vol.330
, pp. 576-578
-
-
Doetschman, T.1
Gregg, R.G.2
Maeda, N.3
Hooper, M.L.4
Melton, D.W.5
-
6
-
-
84880570576
-
High-frequency off-target mutagenesis induced by CRISPR-Cas nuclease in human cells
-
1:CAS:528:DC%2BC3sXpvVykur4%3D 3773023 23792628 10.1038/nbt.2623
-
Fu Y, Foden JA, Khayter C, Maeder ML, Reyon D, et al. (2013) High-frequency off-target mutagenesis induced by CRISPR-Cas nuclease in human cells. Nat Biotechnol 31:822-826
-
(2013)
Nat Biotechnol
, vol.31
, pp. 822-826
-
-
Fu, Y.1
Foden, J.A.2
Khayter, C.3
Maeder, M.L.4
Reyon, D.5
-
7
-
-
52149086547
-
Trends in large-scale mouse mutagenesis: From genetics to functional genomics
-
1:CAS:528:DC%2BD1cXhtFeitrnJ 18781157 10.1038/nrg2431
-
Gondo Y (2008) Trends in large-scale mouse mutagenesis: from genetics to functional genomics. Nat Rev Genet 9:803-810
-
(2008)
Nat Rev Genet
, vol.9
, pp. 803-810
-
-
Gondo, Y.1
-
8
-
-
0019847283
-
Integration and stable germ line transmission of genes injected into mouse pronuclei
-
1:CAS:528:DyaL38XivFersA%3D%3D 6272397 10.1126/science.6272397
-
Gordon JW, Ruddle FH (1981) Integration and stable germ line transmission of genes injected into mouse pronuclei. Science 214:1244-1246
-
(1981)
Science
, vol.214
, pp. 1244-1246
-
-
Gordon, J.W.1
Ruddle, F.H.2
-
9
-
-
0036956227
-
Gene-based SNP discovery as part of the Japanese Millennium Genome Project: Identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism
-
1:CAS:528:DC%2BD38XoslOrurY%3D 12436197 10.1007/s100380200092
-
Haga H, Yamada R, Ohnishi Y, Nakamura Y, Tanaka T (2002) Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism. J Hum Genet 47:605-610
-
(2002)
J Hum Genet
, vol.47
, pp. 605-610
-
-
Haga, H.1
Yamada, R.2
Ohnishi, Y.3
Nakamura, Y.4
Tanaka, T.5
-
10
-
-
84881147545
-
Gene knockout and knockin by zinc-finger nucleases: Current status and perspectives
-
1:CAS:528:DC%2BC3sXhtFKlu77M 23161061 10.1007/s00018-012-1204-1
-
Hauschild-Quintern J, Petersen B, Cost GJ, Niemann H (2013) Gene knockout and knockin by zinc-finger nucleases: current status and perspectives. Cell Mol Life Sci 70:2969-2983
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 2969-2983
-
-
Hauschild-Quintern, J.1
Petersen, B.2
Cost, G.J.3
Niemann, H.4
-
11
-
-
0036087166
-
JSNP: A database of common gene variations in the Japanese population
-
1:CAS:528:DC%2BD38Xht12ktb4%3D 99126 11752280 10.1093/nar/30.1.158
-
Hirakawa M, Tanaka T, Hashimoto Y, Kuroda M, Takagi T, et al. (2002) JSNP: a database of common gene variations in the Japanese population. Nucleic Acids Res 30:158-162
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 158-162
-
-
Hirakawa, M.1
Tanaka, T.2
Hashimoto, Y.3
Kuroda, M.4
Takagi, T.5
-
12
-
-
84863503465
-
A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations
-
1:CAS:528:DC%2BC38Xos1yltLs%3D 22456796 10.1093/hmg/dds113
-
Imamura M, Maeda S, Yamauchi T, Hara K, Yasuda K, et al. (2012) A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations. Hum Mol Genet 21:3042-3049
-
(2012)
Hum Mol Genet
, vol.21
, pp. 3042-3049
-
-
Imamura, M.1
Maeda, S.2
Yamauchi, T.3
Hara, K.4
Yasuda, K.5
-
13
-
-
79955788680
-
Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese
-
1:CAS:528:DC%2BC3MXmtFWhtLg%3D 3089633 21573128 10.1371/journal.pone. 0019641
-
Kou I, Takahashi A, Urano T, Fukui N, Ito H, et al. (2011) Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese. PLoS ONE 6:e19641
-
(2011)
PLoS ONE
, vol.6
, pp. 19641
-
-
Kou, I.1
Takahashi, A.2
Urano, T.3
Fukui, N.4
Ito, H.5
-
14
-
-
0030588070
-
Base substitution at different alternative splice donor sites of the tyrosinase gene in murine albinism
-
10.1006/geno.1996.0551
-
Le FN, Kelsall SR, Mintz B (1996) Base substitution at different alternative splice donor sites of the tyrosinase gene in murine albinism. Genomics 37:245-248
-
(1996)
Genomics
, vol.37
, pp. 245-248
-
-
Le, F.N.1
Kelsall, S.R.2
Mintz, B.3
-
15
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
1:CAS:528:DC%2BC3sXit1ygtb0%3D 3712628 23287722 10.1126/science.1232033
-
Mali P, Yang L, Esvelt KM, Aach J, Guell M, et al. (2013) RNA-guided human genome engineering via Cas9. Science 339:823-826
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
-
16
-
-
84889589440
-
Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA
-
3842082 24284873 10.1038/srep03355
-
Mashiko D, Fujihara Y, Satouh Y, Miyata H, Isotani A, et al. (2013) Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA. Sci Rep. 3:3355
-
(2013)
Sci Rep.
, vol.3
, pp. 3355
-
-
Mashiko, D.1
Fujihara, Y.2
Satouh, Y.3
Miyata, H.4
Isotani, A.5
-
17
-
-
84892659943
-
Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes
-
1:CAS:528:DC%2BC2cXht1eiu7g%3D 24372541 10.1111/dgd.12113
-
Mashiko D, Young SA, Muto M, Kato H, Nozawa K (2014) Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes. Dev Growth Differ 56:122-129
-
(2014)
Dev Growth Differ
, vol.56
, pp. 122-129
-
-
Mashiko, D.1
Young, S.A.2
Muto, M.3
Kato, H.4
Nozawa, K.5
-
18
-
-
78650974285
-
A novel locus on proximal chromosome 18 associated with agenesis of the corpus callosum in mice
-
20967545 10.1007/s00335-010-9292-4
-
Mizuno S, Mizobuchi A, Iseki H, Iijima S, Matsuda Y, et al. (2010) A novel locus on proximal chromosome 18 associated with agenesis of the corpus callosum in mice. Mamm Genome 21:525-533
-
(2010)
Mamm Genome
, vol.21
, pp. 525-533
-
-
Mizuno, S.1
Mizobuchi, A.2
Iseki, H.3
Iijima, S.4
Matsuda, Y.5
-
19
-
-
34548633862
-
Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C→T (Arg493X) mutation: An international initiative
-
1:CAS:528:DC%2BD2sXht1Krtr7O 17826340 10.1016/S1474-4422(07)70221-1
-
Rademakers R, Baker M, Gass J, Adamson J, Huey ED, et al. (2007) Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C→T (Arg493X) mutation: an international initiative. Lancet Neurol 6:857-868
-
(2007)
Lancet Neurol
, vol.6
, pp. 857-868
-
-
Rademakers, R.1
Baker, M.2
Gass, J.3
Adamson, J.4
Huey, E.D.5
-
20
-
-
58149397222
-
Bioluminescence imaging modality for in vitro and in vivo gene expression
-
10.1007/978-1-60327-517-0-29
-
Sadiko RT, Blackwell TS (2008) Bioluminescence imaging modality for in vitro and in vivo gene expression. Methods Mol Biol 477:383-394
-
(2008)
Methods Mol Biol
, vol.477
, pp. 383-394
-
-
Sadiko, R.T.1
Blackwell, T.S.2
-
21
-
-
20044382684
-
In vivo bioluminescence imaging
-
1:CAS:528:DC%2BD2MXnvFekug%3D%3D 15679260
-
Sato A, Kaaunber B, Tolwani T (2004) In vivo bioluminescence imaging. Comp Med 54:631-634
-
(2004)
Comp Med
, vol.54
, pp. 631-634
-
-
Sato, A.1
Kaaunber, B.2
Tolwani, T.3
-
22
-
-
84864500003
-
Noninvasive monitoring of β-cell mass and fetal β-cell genesis in mice using bioluminescence imaging
-
1:CAS:528:DC%2BC3sXhslert7%2FK 22850644 10.1538/expanim.61.445
-
Sekiguchi Y, Owada J, Oishi H, Katsumata T, Ikeda K, et al. (2012) Noninvasive monitoring of β-cell mass and fetal β-cell genesis in mice using bioluminescence imaging. Exp Anim 61:445-451
-
(2012)
Exp Anim
, vol.61
, pp. 445-451
-
-
Sekiguchi, Y.1
Owada, J.2
Oishi, H.3
Katsumata, T.4
Ikeda, K.5
-
23
-
-
84872194963
-
Knockout mice created by TALEN-mediated gene targeting
-
1:CAS:528:DC%2BC3sXltVCksg%3D%3D 23302927 10.1038/nbt.2477
-
Sung YH, Baek IJ, Kim DH, Jeon J, Lee J, et al. (2013) Knockout mice created by TALEN-mediated gene targeting. Nat Biotechnol 31:23-24
-
(2013)
Nat Biotechnol
, vol.31
, pp. 23-24
-
-
Sung, Y.H.1
Baek, I.J.2
Kim, D.H.3
Jeon, J.4
Lee, J.5
-
24
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
1:CAS:528:DC%2BC3sXmvF2nt7w%3D 3969854 23643243 10.1016/j.cell.2013.04. 025
-
Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, et al. (2013) One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153:910-918
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
-
25
-
-
84857097177
-
RNA-guided genetic silencing systems in bacteria and archaea
-
1:CAS:528:DC%2BC38Xit12jur4%3D 22337052 10.1038/nature10886
-
Wiedenheft B, Sternberg SH, Doudna JA (2012) RNA-guided genetic silencing systems in bacteria and archaea. Nature 482:331-338
-
(2012)
Nature
, vol.482
, pp. 331-338
-
-
Wiedenheft, B.1
Sternberg, S.H.2
Doudna, J.A.3
-
26
-
-
84890050551
-
Correction of a genetic disease in mouse via use of CRISPR-Cas9
-
1:CAS:528:DC%2BC3sXhvFymtbzN 24315440 10.1016/j.stem.2013.10.016
-
Wu Y, Liang D, Wang Y, Bai M, Tang W (2013) Correction of a genetic disease in mouse via use of CRISPR-Cas9. Cell Stem Cell 13:659-662
-
(2013)
Cell Stem Cell
, vol.13
, pp. 659-662
-
-
Wu, Y.1
Liang, D.2
Wang, Y.3
Bai, M.4
Tang, W.5
-
27
-
-
84884289608
-
One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering
-
1:CAS:528:DC%2BC3sXhtlGqtr%2FN 23992847 10.1016/j.cell.2013.08.022
-
Yang H, Wang H, Shivalila CS, Cheng AW, Shi L, et al. (2013) One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering. Cell 154:1370-1379
-
(2013)
Cell
, vol.154
, pp. 1370-1379
-
-
Yang, H.1
Wang, H.2
Shivalila, C.S.3
Cheng, A.W.4
Shi, L.5
|