High resistance of the mechanical properties of the chondrocyte pericellular matrix to proteoglycan digestion by chondroitinase, aggrecanase, or hyaluronidase

Journal of the Mechanical Behavior of Biomedical Materials

Volumn 38, Issue , 2014, Pages 183-197

  Wilusz, Rebecca E ^a,b   Guilak, Farshid ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b USA   (United States)

Author keywords

Aggrecanase; Atomic force microscopy; Chondroitin sulfate; Chondron; Hyaluronic acid; Perlecan; Type VI collagen

Indexed keywords

ATOMIC FORCE MICROSCOPY; BIOMECHANICS; BODY FLUIDS; COLLAGEN; ELASTIC MODULI; GLYCOPROTEINS; HYALURONIC ACID; TISSUE;

AGGRECANASE; BIOMECHANICAL PROPERTIES; CHONDROITIN SULFATES; CHONDRON; EXTRACELLULAR MATRICES; MICROMECHANICAL PROPERTY; NON-COLLAGENOUS PROTEINS; PERLECAN;

CARTILAGE;

AGGRECAN; AGGRECANASE; AGGRECANASE 1; CHONDROITIN; CHONDROITIN ABC LYASE; COLLAGEN TYPE 6; DERMATAN SULFATE; HYALURONIC ACID; HYALURONIDASE; LEUKOCYTE ELASTASE; N ACETYLGALACTOSAMINE 4 SULFATASE; PROTEOGLYCAN; HYALURONOGLUCOSAMINIDASE; PROTEINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; ATOMIC FORCE MICROSCOPY; CARTILAGE CELL; CONTROLLED STUDY; ENZYMATIC DEGRADATION; ENZYME THERAPY; EXTRACELLULAR MATRIX; HISTOLOGY; IMMUNOFLUORESCENCE; LEUKOCYTE; MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN METABOLISM; RIGIDITY; SWINE; ANIMAL; BIOMECHANICS; CYTOLOGY; HUMAN; MATERIALS TESTING; METABOLISM; PROTEIN DEGRADATION;

ANIMALS; BIOMECHANICAL PHENOMENA; CHONDROCYTES; CHONDROITINASES AND CHONDROITIN LYASES; ENDOPEPTIDASES; EXTRACELLULAR MATRIX; HUMANS; HYALURONOGLUCOSAMINIDASE; MATERIALS TESTING; MECHANICAL PROCESSES; PROTEOGLYCANS; PROTEOLYSIS; SWINE;

EID: 84905594257     PISSN: 17516161     EISSN: 18780180     Source Type: Journal    
DOI: 10.1016/j.jmbbm.2013.09.021     Document Type: Article

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