The dynamic mechanical environment of the chondrocyte: A biphasic finite element model of cell-matrix interactions under cyclic compressive loading

Journal of Biomechanical Engineering

Volumn 130, Issue 6, 2008, Pages

  Kim, Eunjung ^a   Guilak, Farshid ^b   Haider, Mansoor A ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Chondron; Collagen; Finite element method; Poroelastic; Proteoglycan

Indexed keywords

AMPLIFICATION FACTORS; ARTICULAR CARTILAGES; AXIAL STRAINS; AXISYMMETRIC; BIPHASIC; BIPHASIC MATERIALS; BIPHASIC REGIONS; BIPHASIC THEORIES; CELLULAR ENVIRONMENTS; CELLULAR MICROENVIRONMENT; CHONDROCYTE; CHONDROCYTES; CHONDRON; COMPRESSIVE LOADINGS; CYCLIC MECHANICAL LOADINGS; DYNAMIC LOADING CONDITIONS; DYNAMIC MECHANICALS; EXTRACELLULAR MATRIXES; FINITE ELEMENT MODELS; GEL DIFFUSIONS; HIGHER FREQUENCIES; IN VITRO; LOADING FREQUENCIES; MACROSCOPIC LOADINGS; MATERIAL PROPERTIES; MECHANICAL TRANSDUCERS; METABOLIC ACTIVITIES; MICROPIPETTE ASPIRATIONS; MULTISCALE MODELS; MULTISCALE SIMULATIONS; OSTEO ARTHRITISES; OSTEOARTHRITIC CARTILAGES; PERICELLULAR MATRIXES; POROELASTIC; PROTECTIVE LAYERS; PROTEOGLYCAN; QUANTITATIVE RELATIONSHIPS; RELATIVE MAGNITUDES; STRAIN AMPLIFICATIONS; TIME VARYING; WEIGHTED RESIDUAL FORMULATIONS;

AMPLIFICATION; BIOMECHANICS; BODY FLUIDS; BOUNDARY VALUE PROBLEMS; CARTILAGE; COLLAGEN; COLLOIDS; DYNAMIC LOADS; ELECTRIC DISCHARGE MACHINING; ENZYME ACTIVITY; FLOW INTERACTIONS; GELATION; LIGAMENTS; LOADING; ORGANIC POLYMERS; PULSE CODE MODULATION; STIFFNESS MATRIX; TISSUE; ULTRASONIC MEASUREMENT;

FINITE ELEMENT METHOD;

ANIMAL; ARTICLE; BIOLOGICAL MODEL; CARTILAGE CELL; COMPRESSIVE STRENGTH; COMPUTER SIMULATION; EXTRACELLULAR MATRIX; FINITE ELEMENT ANALYSIS; HUMAN; MECHANICAL STRESS; MECHANOTRANSDUCTION; METHODOLOGY; PHYSIOLOGY; POROSITY; STIMULATION; YOUNG MODULUS;

ANIMALS; CHONDROCYTES; COMPRESSIVE STRENGTH; COMPUTER SIMULATION; ELASTIC MODULUS; EXTRACELLULAR MATRIX; FINITE ELEMENT ANALYSIS; HUMANS; MECHANOTRANSDUCTION, CELLULAR; MODELS, BIOLOGICAL; PHYSICAL STIMULATION; POROSITY; STRESS, MECHANICAL;

EID: 58149202349     PISSN: 01480731     EISSN: None     Source Type: Journal    
DOI: 10.1115/1.2978991     Document Type: Article

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