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Volumn 112, Issue 4, 2014, Pages 513-519

Oral administration of the milk casein-derived tripeptide Val-Pro-Pro attenuates high-fat diet-induced adipose tissue inflammation in mice

Author keywords

Adipose tissue; Casein derived tripeptides; High fat diet; Inflammation; Macrophages

Indexed keywords

CASEIN; CD18 ANTIGEN; CHEMOKINE RECEPTOR CCR2; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; RNA 18S; TAP WATER; TRIPEPTIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VALYLPROPYLPROLINE; ANTIINFLAMMATORY AGENT; INTEGRIN; MILK PROTEIN; VALINE PROLINE PROLINE;

EID: 84905593386     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114514001147     Document Type: Article
Times cited : (39)

References (42)
  • 1
    • 0348230958 scopus 로고    scopus 로고
    • Obesity is associated with macrophage accumulation in adipose tissue
    • Weisberg SP, McCann D, Desai M, et al. (2003) Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112, 1796-1808.
    • (2003) J Clin Invest , vol.112 , pp. 1796-1808
    • Weisberg, S.P.1    McCann, D.2    Desai, M.3
  • 2
    • 33845914986 scopus 로고    scopus 로고
    • Mechanisms linking obesity with cardiovascular disease
    • Van Gaal LF, Mertens IL & De Block CE (2006) Mechanisms linking obesity with cardiovascular disease. Nature 444, 875-880.
    • (2006) Nature , vol.444 , pp. 875-880
    • Van Gaal, L.F.1    Mertens, I.L.2    De Block, C.E.3
  • 3
    • 42449097289 scopus 로고    scopus 로고
    • Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
    • Guilherme A, Virbasius JV, Puri V, et al. (2008) Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat Rev Mol Cell Biol 9, 367-377.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 367-377
    • Guilherme, A.1    Virbasius, J.V.2    Puri, V.3
  • 4
    • 0029286291 scopus 로고
    • Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk
    • Nakamura Y, Yamamoto N, Sakai K, et al. (1995) Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk. J Dairy Sci 78, 777-783.
    • (1995) J Dairy Sci , vol.78 , pp. 777-783
    • Nakamura, Y.1    Yamamoto, N.2    Sakai, K.3
  • 5
    • 6944241742 scopus 로고    scopus 로고
    • Release of short and proline-rich antihypertensive peptides from casein hydrolysate with an Aspergillus oryzae protease
    • Mizuno S, Nishimura S, Matsuura K, et al. (2004) Release of short and proline-rich antihypertensive peptides from casein hydrolysate with an Aspergillus oryzae protease. J Dairy Sci 87, 3183-3188.
    • (2004) J Dairy Sci , vol.87 , pp. 3183-3188
    • Mizuno, S.1    Nishimura, S.2    Matsuura, K.3
  • 6
    • 79959288378 scopus 로고    scopus 로고
    • Blood pressure lowering effect of lactotripeptides assumed as functional foods: A meta-analysis of current available clinical trials
    • Cicero AF, Gerocarni B, Laghi L, et al. (2011) Blood pressure lowering effect of lactotripeptides assumed as functional foods: A meta-analysis of current available clinical trials. J Hum Hypertens 25, 425-436.
    • (2011) J Hum Hypertens , vol.25 , pp. 425-436
    • Cicero, A.F.1    Gerocarni, B.2    Laghi, L.3
  • 7
    • 84876557415 scopus 로고    scopus 로고
    • Do the lactotripeptides isoleucine-proline-proline and valine-prolineproline reduce systolic blood pressure in European subjects? A meta-analysis of randomized controlled trials
    • Cicero AF, Aubin F, Azais-Braesco V, et al. (2013) Do the lactotripeptides isoleucine-proline-proline and valine-prolineproline reduce systolic blood pressure in European subjects? A meta-analysis of randomized controlled trials. Am J Hypertens 26, 442-449.
    • (2013) Am J Hypertens , vol.26 , pp. 442-449
    • Cicero, A.F.1    Aubin, F.2    Azais-Braesco, V.3
  • 8
    • 84855726245 scopus 로고    scopus 로고
    • Milk caseinderived tripeptides, VPP and IPP induced NO production in cultured endothelial cells and endothelium-dependent relaxation of isolated aortic rings
    • Hirota T, Nonaka A, Matsushita A, et al. (2011) Milk caseinderived tripeptides, VPP and IPP induced NO production in cultured endothelial cells and endothelium-dependent relaxation of isolated aortic rings. Heart Vessels 26, 549-556.
    • (2011) Heart Vessels , vol.26 , pp. 549-556
    • Hirota, T.1    Nonaka, A.2    Matsushita, A.3
  • 9
    • 34447567157 scopus 로고    scopus 로고
    • Casein hydrolysate containing the antihypertensive tripeptides Val-Pro-Pro and Ile-Pro-Pro improves vascular endothelial function independent of blood pressure-lowering effects: Contribution of the inhibitory action of angiotensin-converting enzyme
    • Hirota T, Ohki K, Kawagishi R, et al. (2007) Casein hydrolysate containing the antihypertensive tripeptides Val-Pro-Pro and Ile-Pro-Pro improves vascular endothelial function independent of blood pressure-lowering effects: Contribution of the inhibitory action of angiotensin-converting enzyme. Hypertens Res 30, 489-496.
    • (2007) Hypertens Res , vol.30 , pp. 489-496
    • Hirota, T.1    Ohki, K.2    Kawagishi, R.3
  • 10
    • 70350448855 scopus 로고    scopus 로고
    • Additive beneficial effects of lactotripeptides and aerobic exercise on arterial compliance in postmenopausal women
    • Yoshizawa M, Maeda S, Miyaki A, et al. (2009) Additive beneficial effects of lactotripeptides and aerobic exercise on arterial compliance in postmenopausal women. Am J Physiol Heart Circ Physiol 297, H1899-H1903.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Yoshizawa, M.1    Maeda, S.2    Miyaki, A.3
  • 11
    • 80052476500 scopus 로고    scopus 로고
    • Casein hydrolysate containing Val-Pro-Pro and Ile-Pro-Pro improves central blood pressure and arterial stiffness in hypertensive subjects: A randomized, double-blind, placebo-controlled trial
    • Nakamura T, Mizutani J, Ohki K, et al. (2011) Casein hydrolysate containing Val-Pro-Pro and Ile-Pro-Pro improves central blood pressure and arterial stiffness in hypertensive subjects: A randomized, double-blind, placebo-controlled trial. Atherosclerosis 219, 298-303.
    • (2011) Atherosclerosis , vol.219 , pp. 298-303
    • Nakamura, T.1    Mizutani, J.2    Ohki, K.3
  • 12
    • 84877869409 scopus 로고    scopus 로고
    • Milkderived peptides, Val-Pro-Pro and Ile-Pro-Pro, attenuate atherosclerosis development in apolipoprotein E-deficient mice: A preliminary study
    • Nakamura T, Hirota T, Mizushima K, et al. (2013) Milkderived peptides, Val-Pro-Pro and Ile-Pro-Pro, attenuate atherosclerosis development in apolipoprotein E-deficient mice: A preliminary study. J Med Food 16, 396-403.
    • (2013) J Med Food , vol.16 , pp. 396-403
    • Nakamura, T.1    Hirota, T.2    Mizushima, K.3
  • 13
    • 73249119117 scopus 로고    scopus 로고
    • Casein-derived tripeptide, Val-Pro-Pro (VPP), modulates monocyte adhesion to vascular endothelium
    • Aihara K, Ishii H & Yoshida M (2009) Casein-derived tripeptide, Val-Pro-Pro (VPP), modulates monocyte adhesion to vascular endothelium. J Atheroscler Thromb 16, 594-603.
    • (2009) J Atheroscler Thromb , vol.16 , pp. 594-603
    • Aihara, K.1    Ishii, H.2    Yoshida, M.3
  • 14
    • 0029000526 scopus 로고
    • Flow cytometric analysis of peripheral blood lymphocyte subset light scatter characteristics as a means of monitoring the development of rat small bowel allograft rejection
    • Webster GA, Bowles MJ, Karim MS, et al. (1995) Flow cytometric analysis of peripheral blood lymphocyte subset light scatter characteristics as a means of monitoring the development of rat small bowel allograft rejection. Clin Exp Immunol 100, 536-542.
    • (1995) Clin Exp Immunol , vol.100 , pp. 536-542
    • Webster, G.A.1    Bowles, M.J.2    Karim, M.S.3
  • 15
    • 0032126447 scopus 로고    scopus 로고
    • Permeabilization and fixation conditions for intracellular flow cytometric detection of the T-cell receptor zeta chain and other intracellular proteins in lymphocyte subpopulations
    • Lazarus AH, Ellis J, Blanchette V, et al. (1998) Permeabilization and fixation conditions for intracellular flow cytometric detection of the T-cell receptor zeta chain and other intracellular proteins in lymphocyte subpopulations. Cytometry 32, 206-213.
    • (1998) Cytometry , vol.32 , pp. 206-213
    • Lazarus, A.H.1    Ellis, J.2    Blanchette, V.3
  • 16
    • 79956318109 scopus 로고    scopus 로고
    • Adipose inflammation initiates recruitment of leukocytes to mouse femoral artery: Role of adipo-vascular axis in chronic inflammation
    • Hagita S, Osaka M, Shimokado K, et al. (2011) Adipose inflammation initiates recruitment of leukocytes to mouse femoral artery: Role of adipo-vascular axis in chronic inflammation. PLoS ONE 6, e19871.
    • (2011) PLoS ONE , vol.6
    • Hagita, S.1    Osaka, M.2    Shimokado, K.3
  • 17
    • 33845298616 scopus 로고    scopus 로고
    • ICAM-1 expression in adipose tissue: Effects of diet-induced obesity in mice
    • Brake DK, Smith EO, Mersmann H, et al. (2006) ICAM-1 expression in adipose tissue: Effects of diet-induced obesity in mice. Am J Physiol Cell Physiol 291, C1232-C1239.
    • (2006) Am J Physiol Cell Physiol , vol.291
    • Brake, D.K.1    Smith, E.O.2    Mersmann, H.3
  • 18
    • 75149197353 scopus 로고    scopus 로고
    • CD11c expression in adipose tissue and blood and its role in diet-induced obesity
    • Wu H, Perrard XD, Wang Q, et al. (2010) CD11c expression in adipose tissue and blood and its role in diet-induced obesity. Arterioscler Thromb Vasc Biol 30, 186-192.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 186-192
    • Wu, H.1    Perrard, X.D.2    Wang, Q.3
  • 19
    • 58149102605 scopus 로고    scopus 로고
    • Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue
    • Ito A, Suganami T, Yamauchi A, et al. (2008) Role of CC chemokine receptor 2 in bone marrow cells in the recruitment of macrophages into obese adipose tissue. J Biol Chem 283, 35715-35723.
    • (2008) J Biol Chem , vol.283 , pp. 35715-35723
    • Ito, A.1    Suganami, T.2    Yamauchi, A.3
  • 20
    • 79954600458 scopus 로고    scopus 로고
    • Significance of M2-polarized tumor-associated macrophage in pancreatic cancer
    • Kurahara H, Shinchi H, Mataki Y, et al. (2011) Significance of M2-polarized tumor-associated macrophage in pancreatic cancer. J Surg Res 167, e211-e219.
    • (2011) J Surg Res , vol.167
    • Kurahara, H.1    Shinchi, H.2    Mataki, Y.3
  • 21
    • 50249144131 scopus 로고    scopus 로고
    • Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas
    • Komohara Y, Ohnishi K, Kuratsu J, et al. (2008) Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas. J Pathol 216, 15-24.
    • (2008) J Pathol , vol.216 , pp. 15-24
    • Komohara, Y.1    Ohnishi, K.2    Kuratsu, J.3
  • 22
    • 71449120759 scopus 로고    scopus 로고
    • Glucocorticoids and thiazolidinediones interfere with adipocyte-mediated macrophage chemotaxis and recruitment
    • Patsouris D, Neels JG, Fan W, et al. (2009) Glucocorticoids and thiazolidinediones interfere with adipocyte-mediated macrophage chemotaxis and recruitment. J Biol Chem 284, 31223-31235.
    • (2009) J Biol Chem , vol.284 , pp. 31223-31235
    • Patsouris, D.1    Neels, J.G.2    Fan, W.3
  • 23
    • 36849005372 scopus 로고    scopus 로고
    • A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
    • Nguyen MT, Favelyukis S, Nguyen AK, et al. (2007) A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem 282, 35279-35292.
    • (2007) J Biol Chem , vol.282 , pp. 35279-35292
    • Nguyen, M.T.1    Favelyukis, S.2    Nguyen, A.K.3
  • 24
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng CN, Bodzin JL & Saltiel AR (2007) Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 117, 175-184.
    • (2007) J Clin Invest , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 25
    • 27444437321 scopus 로고    scopus 로고
    • Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans
    • Cinti S, Mitchell G, Barbatelli G, et al. (2005) Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res 46, 2347-2355.
    • (2005) J Lipid Res , vol.46 , pp. 2347-2355
    • Cinti, S.1    Mitchell, G.2    Barbatelli, G.3
  • 26
    • 34249719581 scopus 로고    scopus 로고
    • Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels
    • Nishimura S, Manabe I, Nagasaki M, et al. (2007) Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels. Diabetes 56, 1517-1526.
    • (2007) Diabetes , vol.56 , pp. 1517-1526
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3
  • 27
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon S & Taylor PR (2005) Monocyte and macrophage heterogeneity. Nat Rev Immunol 5, 953-964.
    • (2005) Nat Rev Immunol , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 28
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • Mantovani A, Sica A, Sozzani S, et al. (2004) The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25, 677-686.
    • (2004) Trends Immunol , vol.25 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3
  • 30
    • 84864825178 scopus 로고    scopus 로고
    • The PepT1-transportable soy tripeptide VPY reduces intestinal inflammation
    • Kovacs-Nolan J, Zhang H, Ibuki M, et al. (2012) The PepT1-transportable soy tripeptide VPY reduces intestinal inflammation. Biochim Biophys Acta 1820, 1753-1763.
    • (2012) Biochim Biophys Acta , vol.1820 , pp. 1753-1763
    • Kovacs-Nolan, J.1    Zhang, H.2    Ibuki, M.3
  • 31
    • 84855321171 scopus 로고    scopus 로고
    • Role of dietary proteins and peptides in cardiovascular disease
    • Cam A & de Mejia EG (2012) Role of dietary proteins and peptides in cardiovascular disease. Mol Nutr Food Res 56, 53-66.
    • (2012) Mol Nutr Food Res , vol.56 , pp. 53-66
    • Cam, A.1    De Mejia, E.G.2
  • 32
    • 67249131192 scopus 로고    scopus 로고
    • Functional role of CD11c\+ monocytes in atherogenesis associated with hypercholesterolemia
    • Wu H, Gower RM, Wang H, et al. (2009) Functional role of CD11c\+ monocytes in atherogenesis associated with hypercholesterolemia. Circulation 119, 2708-2717.
    • (2009) Circulation , vol.119 , pp. 2708-2717
    • Wu, H.1    Gower, R.M.2    Wang, H.3
  • 33
    • 21244443731 scopus 로고    scopus 로고
    • Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences
    • Stout RD, Jiang C, Matta B, et al. (2005) Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J Immunol 175, 342-349.
    • (2005) J Immunol , vol.175 , pp. 342-349
    • Stout, R.D.1    Jiang, C.2    Matta, B.3
  • 34
    • 58149347227 scopus 로고    scopus 로고
    • Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes
    • Lumeng CN, DelProposto JB, Westcott DJ, et al. (2008) Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes. Diabetes 57, 3239-3246.
    • (2008) Diabetes , vol.57 , pp. 3239-3246
    • Lumeng, C.N.1    Delproposto, J.B.2    Westcott, D.J.3
  • 35
    • 31044456529 scopus 로고    scopus 로고
    • CCR2 modulates inflammatory and metabolic effects of high-fat feeding
    • Weisberg SP, Hunter D, Huber R, et al. (2006) CCR2 modulates inflammatory and metabolic effects of high-fat feeding. J Clin Invest 116, 115-124.
    • (2006) J Clin Invest , vol.116 , pp. 115-124
    • Weisberg, S.P.1    Hunter, D.2    Huber, R.3
  • 36
    • 34548434020 scopus 로고    scopus 로고
    • Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue
    • Inouye KE, Shi H, Howard JK, et al. (2007) Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue. Diabetes 56, 2242-2250.
    • (2007) Diabetes , vol.56 , pp. 2242-2250
    • Inouye, K.E.1    Shi, H.2    Howard, J.K.3
  • 37
    • 48449102722 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein deficiency fails to restrain macrophage infiltration into adipose tissue [corrected]
    • Kirk EA, Sagawa ZK, McDonald TO, et al. (2008) Monocyte chemoattractant protein deficiency fails to restrain macrophage infiltration into adipose tissue [corrected]. Diabetes 57, 1254-1261.
    • (2008) Diabetes , vol.57 , pp. 1254-1261
    • Kirk, E.A.1    Sagawa, Z.K.2    McDonald, T.O.3
  • 38
    • 38849118568 scopus 로고    scopus 로고
    • In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue
    • Nishimura S, Manabe I, Nagasaki M, et al. (2008) In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue. J Clin Invest 118, 710-721.
    • (2008) J Clin Invest , vol.118 , pp. 710-721
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3
  • 39
    • 0030469762 scopus 로고    scopus 로고
    • Antihypertensive peptides are present in aorta after oral administration of sour milk containing these peptides to spontaneously hypertensive rats
    • Masuda O, Nakamura Y & Takano T (1996) Antihypertensive peptides are present in aorta after oral administration of sour milk containing these peptides to spontaneously hypertensive rats. J Nutr 126, 3063-3068.
    • (1996) J Nutr , vol.126 , pp. 3063-3068
    • Masuda, O.1    Nakamura, Y.2    Takano, T.3
  • 40
    • 0036479384 scopus 로고    scopus 로고
    • Transepithelial transport of the bioactive tripeptide, Val-Pro-Pro, in human intestinal Caco-2 cell monolayers
    • Satake M, Enjoh M, Nakamura Y, et al. (2002) Transepithelial transport of the bioactive tripeptide, Val-Pro-Pro, in human intestinal Caco-2 cell monolayers. Biosci Biotechnol Biochem 66, 378-384.
    • (2002) Biosci Biotechnol Biochem , vol.66 , pp. 378-384
    • Satake, M.1    Enjoh, M.2    Nakamura, Y.3
  • 41
    • 80051848862 scopus 로고    scopus 로고
    • Producibility and digestibility of antihypertensive beta-casein tripeptides, Val-Pro-Pro and Ile-Pro-Pro, in the gastrointestinal tract: Analyses using an in vitro model of mammalian gastrointestinal digestion
    • Ohsawa K, Satsu H, Ohki K, et al. (2008) Producibility and digestibility of antihypertensive beta-casein tripeptides, Val-Pro-Pro and Ile-Pro-Pro, in the gastrointestinal tract: Analyses using an in vitro model of mammalian gastrointestinal digestion. J Agric Food Chem 56, 854-858.
    • (2008) J Agric Food Chem , vol.56 , pp. 854-858
    • Ohsawa, K.1    Satsu, H.2    Ohki, K.3
  • 42
    • 84866659743 scopus 로고    scopus 로고
    • Accumulation of ACE inhibitory tripeptides, Val-Pro-Pro and Ile-Pro-Pro, in vascular endothelial cells
    • Kawaguchi K, Nakamura T, Kamiie J, et al. (2012) Accumulation of ACE inhibitory tripeptides, Val-Pro-Pro and Ile-Pro-Pro, in vascular endothelial cells. Biosci Biotechnol Biochem 76, 1792-1795.
    • (2012) Biosci Biotechnol Biochem , vol.76 , pp. 1792-1795
    • Kawaguchi, K.1    Nakamura, T.2    Kamiie, J.3


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