The calcineurin signaling network evolves via conserved kinase-phosphatase modules that transcend substrate identity

Molecular Cell

Volumn 55, Issue 3, 2014, Pages 422-435

  Goldman, Aaron ^a   Roy, Jagoree ^a   Bodenmiller, Bernd ^b   Wanka, Stefanie ^b   Landry, Christian R ^c   Aebersold, Ruedi ^b,d   Cyert, Martha S ^a  

^a STANFORD UNIVERSITY   (United States)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITÉ LAVAL   (Canada)

^d ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; COMPUTER MODEL; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MOLECULAR DOCKING; MOLECULAR EVOLUTION; NONHUMAN; PROTEIN DEPHOSPHORYLATION; PROTEIN MOTIF; SACCHAROMYCES CEREVISIAE;

MAMMALIA;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; BINDING SITES; CALCINEURIN; CONSERVED SEQUENCE; EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, FUNGAL; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR DOCKING SIMULATION; PHOSPHORYLATION; PHYLOGENY; PROTEOMICS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY;

EID: 84905574813     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.05.012     Document Type: Article

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