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Volumn 55, Issue 3, 2014, Pages 347-360

Gene silencing triggers polycomb repressive complex 2 recruitment to CpG Islands genome wide

Author keywords

[No Author keywords available]

Indexed keywords

POLYCOMB REPRESSIVE COMPLEX 2;

EID: 84905572005     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.06.005     Document Type: Article
Times cited : (319)

References (51)
  • 1
    • 84870899395 scopus 로고    scopus 로고
    • H3K36me3 key to Polycomb-mediated gene silencing in lineage specification
    • Abed J.A., Jones R.S. H3K36me3 key to Polycomb-mediated gene silencing in lineage specification. Nat. Struct. Mol. Biol. 2012, 19:1214-1215.
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 1214-1215
    • Abed, J.A.1    Jones, R.S.2
  • 2
    • 77958481159 scopus 로고    scopus 로고
    • Nucleosome-interacting proteins regulated by DNA and histone methylation
    • Bartke T., Vermeulen M., Xhemalce B., Robson S.C., Mann M., Kouzarides T. Nucleosome-interacting proteins regulated by DNA and histone methylation. Cell 2010, 143:470-484.
    • (2010) Cell , vol.143 , pp. 470-484
    • Bartke, T.1    Vermeulen, M.2    Xhemalce, B.3    Robson, S.C.4    Mann, M.5    Kouzarides, T.6
  • 3
    • 78751590899 scopus 로고    scopus 로고
    • Silencing chromatin: comparing modes and mechanisms
    • Beisel C., Paro R. Silencing chromatin: comparing modes and mechanisms. Nat. Rev. Genet. 2011, 12:123-135.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 123-135
    • Beisel, C.1    Paro, R.2
  • 4
    • 79958701393 scopus 로고    scopus 로고
    • Inhibiting eukaryotic transcription: Which compound to choose? How to evaluate its activity?
    • Bensaude O. Inhibiting eukaryotic transcription: Which compound to choose? How to evaluate its activity?. Transcription 2011, 2:103-108.
    • (2011) Transcription , vol.2 , pp. 103-108
    • Bensaude, O.1
  • 7
    • 0027470184 scopus 로고
    • Silencers in abdominal-B, a homeotic Drosophila gene
    • Busturia A., Bienz M. Silencers in abdominal-B, a homeotic Drosophila gene. EMBO J. 1993, 12:1415-1425.
    • (1993) EMBO J. , vol.12 , pp. 1415-1425
    • Busturia, A.1    Bienz, M.2
  • 8
    • 3042801308 scopus 로고    scopus 로고
    • SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex
    • Cao R., Zhang Y. SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex. Mol. Cell 2004, 15:57-67.
    • (2004) Mol. Cell , vol.15 , pp. 57-67
    • Cao, R.1    Zhang, Y.2
  • 9
    • 0032524877 scopus 로고    scopus 로고
    • The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis
    • Cavalli G., Paro R. The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis. Cell 1998, 93:505-518.
    • (1998) Cell , vol.93 , pp. 505-518
    • Cavalli, G.1    Paro, R.2
  • 10
    • 48649091905 scopus 로고    scopus 로고
    • Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency
    • Chamberlain S.J., Yee D., Magnuson T. Polycomb repressive complex 2 is dispensable for maintenance of embryonic stem cell pluripotency. Stem Cells 2008, 26:1496-1505.
    • (2008) Stem Cells , vol.26 , pp. 1496-1505
    • Chamberlain, S.J.1    Yee, D.2    Magnuson, T.3
  • 11
    • 0028321783 scopus 로고
    • A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression
    • Chan C.S., Rastelli L., Pirrotta V. A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression. EMBO J. 1994, 13:2553-2564.
    • (1994) EMBO J. , vol.13 , pp. 2553-2564
    • Chan, C.S.1    Rastelli, L.2    Pirrotta, V.3
  • 12
    • 77952996319 scopus 로고    scopus 로고
    • Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones
    • Deal R.B., Henikoff J.G., Henikoff S. Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones. Science 2010, 328:1161-1164.
    • (2010) Science , vol.328 , pp. 1161-1164
    • Deal, R.B.1    Henikoff, J.G.2    Henikoff, S.3
  • 13
    • 79956330964 scopus 로고    scopus 로고
    • CpG islands and the regulation of transcription
    • Deaton A.M., Bird A. CpG islands and the regulation of transcription. Genes Dev. 2011, 25:1010-1022.
    • (2011) Genes Dev. , vol.25 , pp. 1010-1022
    • Deaton, A.M.1    Bird, A.2
  • 14
    • 0031699524 scopus 로고    scopus 로고
    • The Polycomb-group gene eed is required for normal morphogenetic movements during gastrulation in the mouse embryo
    • Faust C., Lawson K.A., Schork N.J., Thiel B., Magnuson T. The Polycomb-group gene eed is required for normal morphogenetic movements during gastrulation in the mouse embryo. Development 1998, 125:4495-4506.
    • (1998) Development , vol.125 , pp. 4495-4506
    • Faust, C.1    Lawson, K.A.2    Schork, N.J.3    Thiel, B.4    Magnuson, T.5
  • 15
    • 84859867313 scopus 로고    scopus 로고
    • In vivo Polycomb kinetics and mitotic chromatin binding distinguish stem cells from differentiated cells
    • Fonseca J.P., Steffen P.A., Müller S., Lu J., Sawicka A., Seiser C., Ringrose L. In vivo Polycomb kinetics and mitotic chromatin binding distinguish stem cells from differentiated cells. Genes Dev. 2012, 26:857-871.
    • (2012) Genes Dev. , vol.26 , pp. 857-871
    • Fonseca, J.P.1    Steffen, P.A.2    Müller, S.3    Lu, J.4    Sawicka, A.5    Seiser, C.6    Ringrose, L.7
  • 17
    • 84886808679 scopus 로고    scopus 로고
    • Chromatin proteins and modifications as drug targets
    • Helin K., Dhanak D. Chromatin proteins and modifications as drug targets. Nature 2013, 502:480-488.
    • (2013) Nature , vol.502 , pp. 480-488
    • Helin, K.1    Dhanak, D.2
  • 18
  • 20
    • 0025149495 scopus 로고
    • Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster
    • Jones R.S., Gelbart W.M. Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster. Genetics 1990, 126:185-199.
    • (1990) Genetics , vol.126 , pp. 185-199
    • Jones, R.S.1    Gelbart, W.M.2
  • 21
    • 84887460647 scopus 로고    scopus 로고
    • PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells
    • Kaneko S., Son J., Shen S.S., Reinberg D., Bonasio R. PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells. Nat. Struct. Mol. Biol. 2013, 20:1258-1264.
    • (2013) Nat. Struct. Mol. Biol. , vol.20 , pp. 1258-1264
    • Kaneko, S.1    Son, J.2    Shen, S.S.3    Reinberg, D.4    Bonasio, R.5
  • 23
    • 84884626274 scopus 로고    scopus 로고
    • Chromatin sampling-an emerging perspective on targeting polycomb repressor proteins
    • Klose R.J., Cooper S., Farcas A.M., Blackledge N.P., Brockdorff N. Chromatin sampling-an emerging perspective on targeting polycomb repressor proteins. PLoS Genet. 2013, 9:e1003717.
    • (2013) PLoS Genet. , vol.9
    • Klose, R.J.1    Cooper, S.2    Farcas, A.M.3    Blackledge, N.P.4    Brockdorff, N.5
  • 24
    • 2442594080 scopus 로고    scopus 로고
    • The histone methyltransferases Trithorax and Ash1 prevent transcriptional silencing by Polycomb group proteins
    • Klymenko T., Müller J. The histone methyltransferases Trithorax and Ash1 prevent transcriptional silencing by Polycomb group proteins. EMBO Rep. 2004, 5:373-377.
    • (2004) EMBO Rep. , vol.5 , pp. 373-377
    • Klymenko, T.1    Müller, J.2
  • 26
    • 76149142791 scopus 로고    scopus 로고
    • Polycomb complexes act redundantly to repress genomic repeats and genes
    • Leeb M., Pasini D., Novatchkova M., Jaritz M., Helin K., Wutz A. Polycomb complexes act redundantly to repress genomic repeats and genes. Genes Dev. 2010, 24:265-276.
    • (2010) Genes Dev. , vol.24 , pp. 265-276
    • Leeb, M.1    Pasini, D.2    Novatchkova, M.3    Jaritz, M.4    Helin, K.5    Wutz, A.6
  • 28
    • 78751662908 scopus 로고    scopus 로고
    • The Polycomb complex PRC2 and its mark in life
    • Margueron R., Reinberg D. The Polycomb complex PRC2 and its mark in life. Nature 2011, 469:343-349.
    • (2011) Nature , vol.469 , pp. 343-349
    • Margueron, R.1    Reinberg, D.2
  • 31
    • 33947098453 scopus 로고    scopus 로고
    • Histone replacement marks the boundaries of cis-regulatory domains
    • Mito Y., Henikoff J.G., Henikoff S. Histone replacement marks the boundaries of cis-regulatory domains. Science 2007, 315:1408-1411.
    • (2007) Science , vol.315 , pp. 1408-1411
    • Mito, Y.1    Henikoff, J.G.2    Henikoff, S.3
  • 34
    • 8144230178 scopus 로고    scopus 로고
    • Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity
    • Pasini D., Bracken A.P., Jensen M.R., Lazzerini Denchi E., Helin K. Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity. EMBO J. 2004, 23:4061-4071.
    • (2004) EMBO J. , vol.23 , pp. 4061-4071
    • Pasini, D.1    Bracken, A.P.2    Jensen, M.R.3    Lazzerini Denchi, E.4    Helin, K.5
  • 35
    • 34248169728 scopus 로고    scopus 로고
    • The polycomb group protein Suz12 is required for embryonic stem cell differentiation
    • Pasini D., Bracken A.P., Hansen J.B., Capillo M., Helin K. The polycomb group protein Suz12 is required for embryonic stem cell differentiation. Mol. Cell. Biol. 2007, 27:3769-3779.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 3769-3779
    • Pasini, D.1    Bracken, A.P.2    Hansen, J.B.3    Capillo, M.4    Helin, K.5
  • 37
    • 15444361900 scopus 로고    scopus 로고
    • Intergenic transcription through a polycomb group response element counteracts silencing
    • Schmitt S., Prestel M., Paro R. Intergenic transcription through a polycomb group response element counteracts silencing. Genes Dev. 2005, 19:697-708.
    • (2005) Genes Dev. , vol.19 , pp. 697-708
    • Schmitt, S.1    Prestel, M.2    Paro, R.3
  • 38
    • 84888001513 scopus 로고    scopus 로고
    • A new world of Polycombs: unexpected partnerships and emerging functions
    • Schwartz Y.B., Pirrotta V. A new world of Polycombs: unexpected partnerships and emerging functions. Nat. Rev. Genet. 2013, 14:853-864.
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 853-864
    • Schwartz, Y.B.1    Pirrotta, V.2
  • 39
    • 2542513044 scopus 로고    scopus 로고
    • General transcriptional silencing by a Polycomb response element in Drosophila
    • Sengupta A.K., Kuhrs A., Müller J. General transcriptional silencing by a Polycomb response element in Drosophila. Development 2004, 131:1959-1965.
    • (2004) Development , vol.131 , pp. 1959-1965
    • Sengupta, A.K.1    Kuhrs, A.2    Müller, J.3
  • 40
    • 55949124844 scopus 로고    scopus 로고
    • EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency
    • Shen X., Liu Y., Hsu Y.-J., Fujiwara Y., Kim J., Mao X., Yuan G.-C., Orkin S.H. EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Mol. Cell 2008, 32:491-502.
    • (2008) Mol. Cell , vol.32 , pp. 491-502
    • Shen, X.1    Liu, Y.2    Hsu, Y.-J.3    Fujiwara, Y.4    Kim, J.5    Mao, X.6    Yuan, G.-C.7    Orkin, S.H.8
  • 41
    • 84876871047 scopus 로고    scopus 로고
    • Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put
    • Simon J.A., Kingston R.E. Occupying chromatin: Polycomb mechanisms for getting to genomic targets, stopping transcriptional traffic, and staying put. Mol. Cell 2013, 49:808-824.
    • (2013) Mol. Cell , vol.49 , pp. 808-824
    • Simon, J.A.1    Kingston, R.E.2
  • 42
    • 0026503711 scopus 로고
    • Ten different Polycomb group genes are required for spatial control of the abdA and AbdB homeotic products
    • Simon J., Chiang A., Bender W. Ten different Polycomb group genes are required for spatial control of the abdA and AbdB homeotic products. Development 1992, 114:493-505.
    • (1992) Development , vol.114 , pp. 493-505
    • Simon, J.1    Chiang, A.2    Bender, W.3
  • 44
    • 0022326910 scopus 로고
    • Altered distributions of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila
    • Struhl G., Akam M. Altered distributions of Ultrabithorax transcripts in extra sex combs mutant embryos of Drosophila. EMBO J. 1985, 4:3259-3264.
    • (1985) EMBO J. , vol.4 , pp. 3259-3264
    • Struhl, G.1    Akam, M.2
  • 46
    • 84879260661 scopus 로고    scopus 로고
    • A double take on bivalent promoters
    • Voigt P., Tee W.-W., Reinberg D. A double take on bivalent promoters. Genes Dev. 2013, 27:1318-1338.
    • (2013) Genes Dev. , vol.27 , pp. 1318-1338
    • Voigt, P.1    Tee, W.-W.2    Reinberg, D.3
  • 48
    • 73149111929 scopus 로고    scopus 로고
    • A region of the human HOXD cluster that confers polycomb-group responsiveness
    • Woo C.J., Kharchenko P.V., Daheron L., Park P.J., Kingston R.E. A region of the human HOXD cluster that confers polycomb-group responsiveness. Cell 2010, 140:99-110.
    • (2010) Cell , vol.140 , pp. 99-110
    • Woo, C.J.1    Kharchenko, P.V.2    Daheron, L.3    Park, P.J.4    Kingston, R.E.5
  • 49
    • 79959950773 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
    • Wray J., Kalkan T., Gomez-Lopez S., Eckardt D., Cook A., Kemler R., Smith A. Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation. Nat. Cell Biol. 2011, 13:838-845.
    • (2011) Nat. Cell Biol. , vol.13 , pp. 838-845
    • Wray, J.1    Kalkan, T.2    Gomez-Lopez, S.3    Eckardt, D.4    Cook, A.5    Kemler, R.6    Smith, A.7
  • 50
    • 77954842322 scopus 로고    scopus 로고
    • Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes
    • Wu H., Coskun V., Tao J., Xie W., Ge W., Yoshikawa K., Li E., Zhang Y., Sun Y.E. Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science 2010, 329:444-448.
    • (2010) Science , vol.329 , pp. 444-448
    • Wu, H.1    Coskun, V.2    Tao, J.3    Xie, W.4    Ge, W.5    Yoshikawa, K.6    Li, E.7    Zhang, Y.8    Sun, Y.E.9
  • 51
    • 84865292901 scopus 로고    scopus 로고
    • Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation
    • Yuan W., Wu T., Fu H., Dai C., Wu H., Liu N., Li X., Xu M., Zhang Z., Niu T., et al. Dense chromatin activates Polycomb repressive complex 2 to regulate H3 lysine 27 methylation. Science 2012, 337:971-975.
    • (2012) Science , vol.337 , pp. 971-975
    • Yuan, W.1    Wu, T.2    Fu, H.3    Dai, C.4    Wu, H.5    Liu, N.6    Li, X.7    Xu, M.8    Zhang, Z.9    Niu, T.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.