Preparation of ibuprofen-loaded chitosan films for oral mucosal drug delivery using supercritical solution impregnation

International Journal of Pharmaceutics

Volumn 473, Issue 1-2, 2014, Pages 434-441

  Tang, Chuan ^a   Guan, Yi Xin ^a   Yao, Shan Jing ^a   Zhu, Zi Qiang ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Ibuprofen; In vitro and ex vivo release; Mucoadhesive chitosan film; Oral mucosal drug delivery system; Supercritical solution impregnation

Indexed keywords

CHITOSAN; IBUPROFEN; DRUG CARRIER; NONSTEROID ANTIINFLAMMATORY AGENT; SOLUTION AND SOLUBILITY;

ANTIBACTERIAL ACTIVITY; ARTICLE; CHEEK MUCOSA; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SYNTHESIS; EX VIVO STUDY; IN VITRO STUDY; MOUTH MUCOSA; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; X RAY DIFFRACTION; ANIMAL; BACTERIAL LOAD; CHEMISTRY; DRUG EFFECTS; DRUG FORMULATION; FEMALE; GROWTH, DEVELOPMENT AND AGING; METABOLISM; ORAL DRUG ADMINISTRATION; PROCEDURES; PSEUDOMONAS AERUGINOSA; RABBIT; SOLUTION AND SOLUBILITY; STAPHYLOCOCCUS AUREUS;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BACTERIAL LOAD; CHITOSAN; DRUG CARRIERS; DRUG COMPOUNDING; FEMALE; IBUPROFEN; MOUTH MUCOSA; PSEUDOMONAS AERUGINOSA; RABBITS; SOLUTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84905511113     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.07.039     Document Type: Article

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