Antiepileptic activity of preferential inhibitors of persistent sodium current

Epilepsia

Volumn 55, Issue 8, 2014, Pages 1274-1283

  Anderson, Lyndsey L ^a   Thompson, Christopher H ^a,b   Hawkins, Nicole A ^b   Nath, Ravi D ^b   Petersohn, Adam A ^b   Rajamani, Sridharan ^c   Bush, William S ^d   Frankel, Wayne N ^e   Vanoye, Carlos G ^a,b   Kearney, Jennifer A ^b   George Jr , Alfred L ^a,b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c GILEAD SCIENCES   (United States)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^e JACKSON LABORATORY   (United States)

Author keywords

Epilepsy; Mossy fiber sprouting; Neurophysiology; Sodium channel

Indexed keywords

ANTICONVULSIVE AGENT; GS 967; RANOLAZINE; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ANGINA PECTORIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELECTRIC SHOCK; EPILEPSY; EXCITABILITY; FOOD AND DRUG ADMINISTRATION; HIPPOCAMPAL MOSSY FIBER; IN VIVO STUDY; LONG TERM CARE; MALE; MOUSE; NERVE CELL; NERVE SPROUTING; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; SODIUM CURRENT; UNITED STATES;

EPILEPSY; MOSSY FIBER SPROUTING; NEUROPHYSIOLOGY; SODIUM CHANNEL;

ACETANILIDES; ANIMALS; ANTICONVULSANTS; CELLS, CULTURED; FEMALE; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NAV1.2 VOLTAGE-GATED SODIUM CHANNEL; NEURONS; PIPERAZINES; PYRIDINES; SEIZURES; SODIUM CHANNEL BLOCKERS; TRIAZOLES;

EID: 84905438888     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/epi.12657     Document Type: Article

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