Saponins from rubus parvifolius L. induce apoptosis in human chronic myeloid leukemia cells through AMPK activation and STAT3 inhibition

Asian Pacific Journal of Cancer Prevention

Volumn 15, Issue 13, 2014, Pages 5455-5461

  Ge, Yu Qing ^a   Xu, Xiao Feng ^b   Yang, Bo ^a   Chen, Zhe ^a   Cheng, Ru Bin ^a  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b Hangzhou Red Cross Hospital   (China)

Author keywords

AMPK; Apoptosis induction; K562 cells; SRP; STAT3 pathways

Indexed keywords

ANTINEOPLASTIC AGENT; CORTICOTROPIN RELEASING FACTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PROTEIN C JUN; SAPONIN; STAT3 PROTEIN; STAT3 PROTEIN, HUMAN; UCN2 PROTEIN, HUMAN; UROCORTIN;

APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; HUMAN; K562 CELL LINE; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; METABOLISM; PHOSPHORYLATION; RUBUS; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CORTICOTROPIN-RELEASING HORMONE; HUMANS; K562 CELLS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-JUN; RUBUS; SAPONINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; UROCORTINS;

EID: 84905385603     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2014.15.13.5455     Document Type: Article

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