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Volumn 118, Issue 24, 2011, Pages 6399-6402

Antileukemic effects of AMPK activators on BCR-ABL-expressing cells

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; BCR ABL PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; METFORMIN;

EID: 83455225509     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-01-332783     Document Type: Article
Times cited : (73)

References (31)
  • 1
    • 58149398623 scopus 로고    scopus 로고
    • Translation of the Philadelphia chromosome into therapy for CML
    • Druker BJ. Translation of the Philadelphia chromosome into therapy for CML. Blood. 2008;112(13):4808-4817.
    • (2008) Blood , vol.112 , Issue.13 , pp. 4808-4817
    • Druker, B.J.1
  • 4
    • 0141508021 scopus 로고    scopus 로고
    • Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin
    • Ly C, Arechiga AF, Melo JV, Walsh CM, Ong ST. Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin. Cancer Res. 2003;63(18):5716-5722. (Pubitemid 37187466)
    • (2003) Cancer Research , vol.63 , Issue.18 , pp. 5716-5722
    • Ly, C.1    Arechiga, A.F.2    Melo, J.V.3    Walsh, C.M.4    Ong, S.T.5
  • 6
    • 33847217892 scopus 로고    scopus 로고
    • A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation
    • Prabhu S, Saadat D, ZhangM, Halbur L, Fruehauf JP, Ong ST. A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation. Oncogene. 2007;26(8):1188-1200.
    • (2007) Oncogene , vol.26 , Issue.8 , pp. 1188-1200
    • Prabhu, S.1    Saadat, D.2    Zhang, M.3    Halbur, L.4    Fruehauf, J.P.5    Ong, S.T.6
  • 9
    • 51349164790 scopus 로고    scopus 로고
    • Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
    • Carracedo A, Ma L, Teruya-Feldstein J, et al. Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer. J Clin Invest. 2008;118(9):3065-3074.
    • (2008) J Clin Invest , vol.118 , Issue.9 , pp. 3065-3074
    • Carracedo, A.1    Ma, L.2    Teruya-Feldstein, J.3
  • 10
    • 43749110929 scopus 로고    scopus 로고
    • Suppression of programmed cell death 4 (PDCD4) protein expression by BCR-ABL-regulated engagement of the mTOR/p70 S6 kinase pathway
    • Carayol N, Katsoulidis E, Sassano A, Altman JK, Druker BJ, Platanias LC. Suppression of programmed cell death 4 (PDCD4) protein expression by BCR-ABL-regulated engagement of the mTOR/p70 S6 kinase pathway. J Biol Chem. 2008;283(13):8601-8610.
    • (2008) J Biol Chem , vol.283 , Issue.13 , pp. 8601-8610
    • Carayol, N.1    Katsoulidis, E.2    Sassano, A.3    Altman, J.K.4    Druker, B.J.5    Platanias, L.C.6
  • 11
    • 76349104427 scopus 로고    scopus 로고
    • Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor
    • Janes MR, Limon JJ, So L, et al. Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor. Nat Med. 2010;16(2):205-213.
    • (2010) Nat Med , vol.16 , Issue.2 , pp. 205-213
    • Janes, M.R.1    Limon, J.J.2    So, L.3
  • 12
    • 77955443001 scopus 로고    scopus 로고
    • Critical roles for mTORC2- and rapamycin-insensitive mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells
    • Carayol N, Vakana E, Sassano A, et al. Critical roles for mTORC2- and rapamycin-insensitive mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells. Proc Natl Acad Sci U S A. 2010;107(28):12469-12474.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.28 , pp. 12469-12474
    • Carayol, N.1    Vakana, E.2    Sassano, A.3
  • 13
    • 0031425839 scopus 로고    scopus 로고
    • AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle
    • Merrill GF, Kurth EJ, Hardie DG, Winder WW. AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle. Am J Physiol. 1997;273(6):E1107-E1112.
    • (1997) Am J Physiol , vol.273 , Issue.6
    • Merrill, G.F.1    Kurth, E.J.2    Hardie, D.G.3    Winder, W.W.4
  • 15
    • 34547114475 scopus 로고    scopus 로고
    • Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentration
    • DOI 10.1152/ajpheart.00002.2007
    • Zhang L, He H, Balschi JA. Metformin and phenformin activate AMP-activated protein kinase in the heart by increasing cytosolic AMP concentration. Am J Physiol Heart Circ Physiol. 2007;293(1):H457-H466. (Pubitemid 47105103)
    • (2007) American Journal of Physiology - Heart and Circulatory Physiology , vol.293 , Issue.1
    • Zhang, L.1    He, H.2    Balschi, J.A.3
  • 17
    • 38349165863 scopus 로고    scopus 로고
    • Regulatory effects of mammalian target of rapamycinmediated signals in the generation of arsenic trioxide responses
    • Altman JK, Yoon P, Katsoulidis E, et al. Regulatory effects of mammalian target of rapamycinmediated signals in the generation of arsenic trioxide responses. J Biol Chem. 2008;283(4):1992-2001.
    • (2008) J Biol Chem , vol.283 , Issue.4 , pp. 1992-2001
    • Altman, J.K.1    Yoon, P.2    Katsoulidis, E.3
  • 18
    • 0028073143 scopus 로고
    • Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase
    • DOI 10.1016/0014-5793(94)01006-4
    • Sullivan JE, Brocklehurst KJ, Marley AE, Carey F, Carling D, Beri RK. Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase. FEBS Lett. 1994;353(1):33-36. (Pubitemid 24312538)
    • (1994) FEBS Letters , vol.353 , Issue.1 , pp. 33-36
    • Sullivan, J.E.1
  • 19
    • 0345167800 scopus 로고    scopus 로고
    • TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
    • DOI 10.1016/S0092-8674(03)00929-2
    • Inoki K, Zhu T, Guan KL. TSC2 mediates cellular energy response to control cell growth and survival. Cell. 2003;115(5):577-590. (Pubitemid 37506046)
    • (2003) Cell , vol.115 , Issue.5 , pp. 577-590
    • Inoki, K.1    Zhu, T.2    Guan, K.-L.3
  • 20
    • 77950930479 scopus 로고    scopus 로고
    • ON012380, a putative BCR-ABL kinase inhibitor with a unique mechanism of action in imatinib-resistant cells
    • Wu J, Meng F, Ying Y, et al. ON012380, a putative BCR-ABL kinase inhibitor with a unique mechanism of action in imatinib-resistant cells. Leukemia. 2010;24(4):869-872.
    • (2010) Leukemia , vol.24 , Issue.4 , pp. 869-872
    • Wu, J.1    Meng, F.2    Ying, Y.3
  • 21
    • 0035542970 scopus 로고    scopus 로고
    • AMP-activated protein kinase: The energy charge hypothesis revisited
    • Hardie DG, Hawley SA. AMP-activated protein kinase: the energy charge hypothesis revisited. Bioessays. 2001;23(12):1112-1119.
    • (2001) Bioessays , vol.23 , Issue.12 , pp. 1112-1119
    • Hardie, D.G.1    Hawley, S.A.2
  • 22
    • 10944247187 scopus 로고    scopus 로고
    • The AMP-activated protein kinase pathway - New players upstream and downstream
    • DOI 10.1242/jcs.01540
    • Hardie DG. The AMP-activated protein kinase pathway: new players upstream and downstream. J Cell Sci. 2004;117(Pt 23):5479-5487. (Pubitemid 40012195)
    • (2004) Journal of Cell Science , vol.117 , Issue.23 , pp. 5479-5487
    • Hardie, D.G.1
  • 23
    • 36348950449 scopus 로고    scopus 로고
    • Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells
    • DOI 10.1158/0008-5472.CAN-07-2310
    • Dowling RJ, Zakikhani M, Fantus IG, Pollak M, Sonenberg N. Metformin inhibits mammalian target of rapamycin-dependent translation initiation in breast cancer cells. Cancer Res. 2007;67(22):10804-10812. (Pubitemid 350145909)
    • (2007) Cancer Research , vol.67 , Issue.22 , pp. 10804-10812
    • Dowling, R.J.O.1    Zakikhani, M.2    Fantus, I.G.3    Pollak, M.4    Sonenberg, N.5
  • 24
    • 79953016397 scopus 로고    scopus 로고
    • Genistein, resveratrol, and 5-aminoimidazole-4- carboxamide-1-beta-D- ribofuranoside induce cytochrome P450 4F2 expression through an AMPactivated protein kinase-dependent pathway
    • Hsu MH, Savas U, Lasker JM, Johnson EF. Genistein, resveratrol, and 5-aminoimidazole-4- carboxamide-1-beta-D-ribofuranoside induce cytochrome P450 4F2 expression through an AMPactivated protein kinase-dependent pathway. J Pharmacol Exp Ther. 2011;337(1):125-136.
    • (2011) J Pharmacol Exp Ther , vol.337 , Issue.1 , pp. 125-136
    • Hsu, M.H.1    Savas, U.2    Lasker, J.M.3    Johnson, E.F.4
  • 25
    • 70849113936 scopus 로고    scopus 로고
    • Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death
    • Robert G, Ben Sahra I, Puissant A, et al. Acadesine kills chronic myelogenous leukemia (CML) cells through PKC-dependent induction of autophagic cell death. PLoS One. 2009;4(11):e7889.
    • (2009) PLoS One , vol.4 , Issue.11
    • Robert, G.1    Ben Sahra, I.2    Puissant, A.3
  • 26
    • 77955287742 scopus 로고    scopus 로고
    • Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner
    • Kalender A, Selvaraj A, Kim SY, et al. Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner. Cell Metab. 2010;11(5):390-401.
    • (2010) Cell Metab , vol.11 , Issue.5 , pp. 390-401
    • Kalender, A.1    Selvaraj, A.2    Kim, S.Y.3
  • 27
    • 34547981921 scopus 로고    scopus 로고
    • Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4- ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: Implication for targeted therapy
    • Sengupta TK, Leclerc GM, Hsieh-Kinser TT, Leclerc GJ, Singh I, Barredo JC. Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy. Mol Cancer. 2007;6:46.
    • (2007) Mol Cancer , vol.6 , pp. 46
    • Sengupta, T.K.1    Leclerc, G.M.2    Hsieh-Kinser, T.T.3    Leclerc, G.J.4    Singh, I.5    Barredo, J.C.6
  • 28
    • 78549283186 scopus 로고    scopus 로고
    • The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation
    • Green AS, Chapuis N, Maciel TT, et al. The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation. Blood. 2010;116(20):4262-4273.
    • (2010) Blood , vol.116 , Issue.20 , pp. 4262-4273
    • Green, A.S.1    Chapuis, N.2    Maciel, T.T.3
  • 29
    • 77954761710 scopus 로고    scopus 로고
    • AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival
    • Woodard J, Platanias LC. AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival. Biochem Biophys Res Commun. 2010;398(1):135-139.
    • (2010) Biochem Biophys Res Commun , vol.398 , Issue.1 , pp. 135-139
    • Woodard, J.1    Platanias, L.C.2
  • 30
    • 77952116629 scopus 로고    scopus 로고
    • Metformin in cancer therapy: A new perspective for an old antidiabetic drug?
    • Ben Sahra I, Le Marchand-Brustel Y, Tanti JF, Bost F. Metformin in cancer therapy: a new perspective for an old antidiabetic drug? Mol Cancer Ther. 2010;9(5):1092-1099.
    • (2010) Mol Cancer Ther , vol.9 , Issue.5 , pp. 1092-1099
    • Ben Sahra, I.1    Le Marchand-Brustel, Y.2    Tanti, J.F.3    Bost, F.4
  • 31
    • 78650949272 scopus 로고    scopus 로고
    • Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity
    • Corbin AS, Agarwal A, Loriaux M, Cortes J, Deininger MW, Druker BJ. Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity. J Clin Invest. 2011;121(1):396-409.
    • (2011) J Clin Invest , vol.121 , Issue.1 , pp. 396-409
    • Corbin, A.S.1    Agarwal, A.2    Loriaux, M.3    Cortes, J.4    Deininger, M.W.5    Druker, B.J.6


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