-
1
-
-
46949091517
-
Refinement and standardization of synthetic biological parts and devices
-
DOI 10.1038/nbt1413, PII NBT1413
-
Canton, B., Labno, A. & Endy, D. Refinement and standardization of synthetic biological parts and devices. Nat. Biotechnol. 26, 787-793 (2008). (Pubitemid 351961452)
-
(2008)
Nature Biotechnology
, vol.26
, Issue.7
, pp. 787-793
-
-
Canton, B.1
Labno, A.2
Endy, D.3
-
2
-
-
0034688174
-
Construction of a genetic toggle switch in Escherichia coli
-
DOI 10.1038/35002131
-
Gardner, T. S., Cantor, C. R. & Collins, J. J. Construction of a genetic toggle switch in Escherichia coli. Nature 403, 339-342 (2000). (Pubitemid 30062394)
-
(2000)
Nature
, vol.403
, Issue.6767
, pp. 339-342
-
-
Gardner, T.S.1
Cantor, C.R.2
Collins, J.J.3
-
3
-
-
34247517470
-
Computer-aided design of modular protein devices: Boolean AND gene activation
-
DOI 10.1088/1478-3975/3/4/007, PII S1478397506253391, 007
-
Salis, H. & Kaznessis, Y. N. Computer-aided design of modular protein devices: Boolean AND gene activation. Phys. Biol. 3, 295-310 (2006). (Pubitemid 46646260)
-
(2006)
Physical Biology
, vol.3
, Issue.4
, pp. 295-310
-
-
Salis, H.1
Kaznessis, Y.N.2
-
4
-
-
71849110893
-
Next-generation synthetic gene networks
-
Lu, T. K., Khalil, A. S. & Collins, J. J. Next-generation synthetic gene networks. Nat. Biotech. 27, 1139-1150 (2009).
-
(2009)
Nat. Biotech.
, vol.27
, pp. 1139-1150
-
-
Lu, T.K.1
Khalil, A.S.2
Collins, J.J.3
-
5
-
-
80055035853
-
Engineering modular and orthogonal genetic logic gates for robust digital-like synthetic biology
-
Wang, B. J., Kitney, R. I., Joly, N. & Buck, M. Engineering modular and orthogonal genetic logic gates for robust digital-like synthetic biology. Nat. Commun. 2, 508 (2011).
-
(2011)
Nat. Commun.
, vol.2
, pp. 508
-
-
Wang, B.J.1
Kitney, R.I.2
Joly, N.3
Buck, M.4
-
6
-
-
84877607428
-
Amplifying genetic logic gates
-
Bonnet, J., Yin, P., Ortiz, M. E., Subsoontorn, P. & Endy, D. Amplifying genetic logic gates. Science 340, 599-603 (2013).
-
(2013)
Science
, vol.340
, pp. 599-603
-
-
Bonnet, J.1
Yin, P.2
Ortiz, M.E.3
Subsoontorn, P.4
Endy, D.5
-
7
-
-
84875230351
-
Synthetic circuits integrating logic and memory in living cells
-
Siuti, P., Yazbek, J. & Lu, T. K. Synthetic circuits integrating logic and memory in living cells. Nat. Biotech. 31, 448-452 (2013).
-
(2013)
Nat. Biotech.
, vol.31
, pp. 448-452
-
-
Siuti, P.1
Yazbek, J.2
Lu, T.K.3
-
8
-
-
84874615774
-
A genetically encoded and gate for cell-targeted metabolic labeling of proteins
-
Mahdavi, A. et al. A genetically encoded AND gate for cell-targeted metabolic labeling of proteins. J. Am. Chem. Soc. 135, 2979-2982 (2013).
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 2979-2982
-
-
Mahdavi, A.1
-
9
-
-
84861193659
-
The radiation dose-regulated and gate genetic circuit, a novel targeted and real-time monitoring strategy for cancer gene therapy
-
Ding, M. et al. The radiation dose-regulated AND gate genetic circuit, a novel targeted and real-time monitoring strategy for cancer gene therapy. Cancer Gene Ther. 19, 382-392 (2012).
-
(2012)
Cancer Gene Ther
, vol.19
, pp. 382-392
-
-
Ding, M.1
-
10
-
-
84857335824
-
A logic-gated nanorobot for targeted transport of molecular payloads
-
Douglas, S. M., Bachelet, I. & Church, G. M. A logic-gated nanorobot for targeted transport of molecular payloads. Science 335, 831-834 (2012).
-
(2012)
Science
, vol.335
, pp. 831-834
-
-
Douglas, S.M.1
Bachelet, I.2
Church, G.M.3
-
11
-
-
0029037739
-
Protein molecules as computational elements in living cells
-
Bray, D. Protein molecules as computational elements in living cells. Nature 376, 307-312 (1995).
-
(1995)
Nature
, vol.376
, pp. 307-312
-
-
Bray, D.1
-
12
-
-
81055129599
-
A mechanism for the evolution of phosphorylation sites
-
Pearlman, S. M., Serber, Z. & Ferrell, J. E. A mechanism for the evolution of phosphorylation sites. Cell 147, 934-946 (2011).
-
(2011)
Cell
, vol.147
, pp. 934-946
-
-
Pearlman, S.M.1
Serber, Z.2
Ferrell, J.E.3
-
13
-
-
80052995647
-
A 'tag-and-modify' approach to site-selective protein modification
-
Chalker, J. M., Bernardes, G. J. L. & Davis, B. G. A 'tag-and-modify' approach to site-selective protein modification. Acc. Chem. Res. 44, 730-741 (2011).
-
(2011)
Acc. Chem. Res.
, vol.44
, pp. 730-741
-
-
Chalker, J.M.1
Bernardes, G.J.L.2
Davis, B.G.3
-
14
-
-
81355138529
-
Methods for converting cysteine to dehydroalanine on peptides and proteins
-
Chalker, J. M. et al. Methods for converting cysteine to dehydroalanine on peptides and proteins. Chem. Sci. 2, 1666-1676 (2011).
-
(2011)
Chem. Sci.
, vol.2
, pp. 1666-1676
-
-
Chalker, J.M.1
-
15
-
-
0027310612
-
Naturally-occurring antibodies devoid of lightchains
-
Hamerscasterman, C. et al. Naturally-occurring antibodies devoid of lightchains. Nature 363, 446-448 (1993).
-
(1993)
Nature
, vol.363
, pp. 446-448
-
-
Hamerscasterman, C.1
-
16
-
-
0029764444
-
Crystal structure of a camel single-domain V(H) antibody fragment in complex with lysozyme
-
DOI 10.1038/nsb0996-803
-
Desmyter, A. et al. Crystal structure of a camel single-domain V-H antibody fragment in complex with lysozyme. Nat. Struct. Biol. 3, 803-811 (1996). (Pubitemid 26303407)
-
(1996)
Nature Structural Biology
, vol.3
, Issue.9
, pp. 803-811
-
-
Desmyter, A.1
Transue, T.R.2
Ghahroudi, M.A.3
Thi, M.-H.D.4
Poortmans, F.5
Hamers, R.6
Muyldermans, S.7
Wyns, L.8
-
17
-
-
67650713930
-
The chemical biology of protein phosphorylation
-
Tarrant, M. K. & Cole, P. A. The chemical biology of protein phosphorylation. Annu. Rev. Biochem. 78, 797-825 (2009).
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 797-825
-
-
Tarrant, M.K.1
Cole, P.A.2
-
18
-
-
15044348175
-
Protein serine/threonine phosphatases: Life, death, and sleeping
-
DOI 10.1016/j.ceb.2005.01.002, Cell Regulation
-
Gallego, M. & Virshup, D. M. Protein serine/threonine phosphatases: life, death, and sleeping. Curr. Opin. Cell. Biol. 17, 197-202 (2005). (Pubitemid 40380944)
-
(2005)
Current Opinion in Cell Biology
, vol.17
, Issue.2
, pp. 197-202
-
-
Gallego, M.1
Virshup, D.M.2
-
19
-
-
84866550022
-
Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance
-
Sun, F. et al. Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance. Proc. Natl Acad. Sci. USA 109, 15461-15466 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 15461-15466
-
-
Sun, F.1
-
20
-
-
0023932371
-
Secreted placental alkaline-phosphatase-A powerful new quantitative indicator of geneexpression in eukaryotic cells
-
Berger, J., Hauber, J., Hauber, R., Geiger, R. & Cullen, B. R. Secreted placental alkaline-phosphatase-a powerful new quantitative indicator of geneexpression in eukaryotic cells. Gene 66, 1-10 (1988).
-
(1988)
Gene
, vol.66
, pp. 1-10
-
-
Berger, J.1
Hauber, J.2
Hauber, R.3
Geiger, R.4
Cullen, B.R.5
-
21
-
-
0027151961
-
Expression of the gene encoding secreted placental alkaline-phosphatase (SEAP) by a nondefective adenovirus vector
-
Doronin, K. K. et al. Expression of the gene encoding secreted placental alkaline-phosphatase (SEAP) by a nondefective adenovirus vector. Gene 126, 247-250 (1993).
-
(1993)
Gene
, vol.126
, pp. 247-250
-
-
Doronin, K.K.1
-
22
-
-
67349162130
-
Tumour necrosis factor and cancer
-
Balkwill, F. Tumour necrosis factor and cancer. Nat. Rev. Cancer 9, 361-371 (2009).
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 361-371
-
-
Balkwill, F.1
-
23
-
-
35348819390
-
Properties, production, and applications of camelid single-domain antibody fragments
-
DOI 10.1007/s00253-007-1142-2
-
Harmsen, M. M. & Haard, H. J. D. Properties, production, and applications of camelid single-domain antibody fragments. Appl. Microbiol. Biotechnol. 77, 13-22 (2007). (Pubitemid 47573319)
-
(2007)
Applied Microbiology and Biotechnology
, vol.77
, Issue.1
, pp. 13-22
-
-
Harmsen, M.M.1
De Haard, H.J.2
-
24
-
-
33750328972
-
Targeting and tracing antigens in live cells with fluorescent nanobodies
-
DOI 10.1038/nmeth953, PII NMETH953
-
Rothbauer, U. et al. Targeting and tracing antigens in live cells with fluorescent nanobodies. Nat. Methods 3, 887-889 (2006). (Pubitemid 44614722)
-
(2006)
Nature Methods
, vol.3
, Issue.11
, pp. 887-889
-
-
Rothbauer, U.1
Zolghadr, K.2
Tillib, S.3
Nowak, D.4
Schermelleh, L.5
Gahl, A.6
Backmann, N.7
Conrath, K.8
Muyldermans, S.9
Cardoso, M.C.10
Leonhardt, H.11
-
25
-
-
77449102676
-
Modulation of protein properties in living cells using nanobodies
-
Kirchhofer, A. et al. Modulation of protein properties in living cells using nanobodies. Nat. Struct. Mol. Biol. 17, 133-138 (2010).
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 133-138
-
-
Kirchhofer, A.1
-
26
-
-
0027265866
-
Regulation of prostatic acid-phosphatase expression and secretion by androgen in lncap human prostate carcinoma-cells
-
Lin, M. F. et al. Regulation of prostatic acid-phosphatase expression and secretion by androgen in lncap human prostate carcinoma-cells. Arch. Biochem. Biophys. 300, 384-390 (1993).
-
(1993)
Arch. Biochem. Biophys.
, vol.300
, pp. 384-390
-
-
Lin, M.F.1
-
27
-
-
33846606299
-
Human breast cancer cell lines and tissues express tartrate-resistant acid phosphatase (TRAP)
-
DOI 10.1016/j.cellbi.2006.09.022, PII S1065699506002150
-
Adams, L. M., Warburton, M. J. & Hayman, A. R. Human breast cancer cell lines and tissues express tartrate-resistant acid phosphatase (TRAP). Cell Biol. Int. 31, 191-195 (2007). (Pubitemid 46187104)
-
(2007)
Cell Biology International
, vol.31
, Issue.2
, pp. 191-195
-
-
Adams, L.M.1
Warburton, M.J.2
Hayman, A.R.3
-
28
-
-
77952298131
-
Design and development of masked therapeutic antibodies to limit off-target effects: Application to anti-EGFR antibodies
-
Donaldson, J. M., Kari, C., Fragoso, R. C., Rodeck, U. & Williams, J. C. Design and development of masked therapeutic antibodies to limit off-target effects: application to anti-EGFR antibodies. Cancer Biol. Ther. 8, 2147-2152 (2009).
-
(2009)
Cancer Biol. Ther.
, vol.8
, pp. 2147-2152
-
-
Donaldson, J.M.1
Kari, C.2
Fragoso, R.C.3
Rodeck, U.4
Williams, J.C.5
-
29
-
-
0021904975
-
Glycosidases in cancer and invasion
-
Bernacki, R. J., Niedbala, M. J. & Korytnyk, W. Glycosidases in cancer and invasion. Cancer Metastasis Rev. 4, 81-101 (1985).
-
(1985)
Cancer Metastasis Rev
, vol.4
, pp. 81-101
-
-
Bernacki, R.J.1
Niedbala, M.J.2
Korytnyk, W.3
-
30
-
-
29044433378
-
O-GlcNAcase catalyzes cleavage of thioglycosides without general acid catalysis
-
DOI 10.1021/ja0567687
-
Macauley, M. S., Stubbs, K. A. & Vocadlo, D. J. O-GlcNAcase catalyzes cleavage of thioglycosides without general acid catalysis. J. Am. Chem. Soc. 127, 17202-17203 (2005). (Pubitemid 41791036)
-
(2005)
Journal of the American Chemical Society
, vol.127
, Issue.49
, pp. 17202-17203
-
-
Macauley, M.S.1
Stubbs, K.A.2
Vocadlo, D.J.3
-
31
-
-
0031558240
-
Antibody-directed enzyme prodrug therapy (ADEPT): A review
-
DOI 10.1016/S0169-409X(97)00032-X, PII S0169409X9700032X
-
Niculescu-Duvaz, I. & Springer, C. J. Antibody-directed enzyme prodrug therapy (ADEPT): a review. Adv. Drug Deliv. Rev. 26, 151-172 (1997). (Pubitemid 27289531)
-
(1997)
Advanced Drug Delivery Reviews
, vol.26
, Issue.2-3
, pp. 151-172
-
-
Niculescu-Duvaz, I.1
Springer, C.J.2
-
32
-
-
25144485908
-
Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence
-
DOI 10.1002/cncr.21326
-
Larson, R. A. et al. Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence. Cancer 104, 1442-1452 (2005). (Pubitemid 41356159)
-
(2005)
Cancer
, vol.104
, Issue.7
, pp. 1442-1452
-
-
Larson, R.A.1
Sievers, E.L.2
Stadtmauer, E.A.3
Lowenberg, B.4
Estey, E.H.5
Dombret, H.6
Theobald, M.7
Voliotis, D.8
Bennett, J.M.9
Richte, M.10
Leopold, L.H.11
Berger, M.S.12
Sherman, M.L.13
Loken, M.R.14
Van Dongen, J.J.M.15
Bernstein, I.D.16
Appelbaum, F.R.17
-
33
-
-
0141757323
-
Reprogramming control of an allosteric signaling switch through modular recombination
-
DOI 10.1126/science.1085945
-
Dueber, J. E., Yeh, B. J., Chak, K. & Lim, W. A. Reprogramming control of an allosteric signaling switch through modular recombination. Science 301, 1904-1908 (2003). (Pubitemid 37221395)
-
(2003)
Science
, vol.301
, Issue.5641
, pp. 1904-1908
-
-
Dueber, J.E.1
Yeh, B.J.2
Chak, K.3
Lim, W.A.4
-
34
-
-
0028129315
-
Computational functions in biochemical reaction networks
-
Arkin, A. & Ross, J. Compuational functions in biochemical reaction networks. Biophys. J. 67, 560-578 (1994). (Pubitemid 24235385)
-
(1994)
Biophysical Journal
, vol.67
, Issue.2
, pp. 560-578
-
-
Arkin, A.1
Ross, J.2
-
35
-
-
33645031060
-
Towards computing with proteins
-
Unger, R. & Moult, J. Towards computing with proteins. Proteins 63, 53-64 (2006).
-
(2006)
Proteins
, vol.63
, pp. 53-64
-
-
Unger, R.1
Moult, J.2
-
36
-
-
0027202171
-
Engineering bispecific antibodies
-
DOI 10.1016/0958-1669(93)90010-T
-
Holliger, P. & Winter, G. Engineering bispecific antibodies. Curr. Opin. Biotechnol. 4, 446-449 (1993). (Pubitemid 23250384)
-
(1993)
Current Opinion in Biotechnology
, vol.4
, Issue.4
, pp. 446-449
-
-
Holliger, P.1
Winter, G.2
-
37
-
-
0032126878
-
Matrix metalloproteinase expression in an experimentally-induced DTH model of multiple sclerosis in the rat CNS
-
DOI 10.1016/S0165-5728(98)00046-0, PII S0165572898000460
-
Anthony, D. C. et al. Matrix metalloproteinase expression in an experimentallyinduced DTH model of multiple sclerosis in the rat CNS. J. Neuroimmunol. 87, 62-72 (1998). (Pubitemid 28319845)
-
(1998)
Journal of Neuroimmunology
, vol.87
, Issue.1-2
, pp. 62-72
-
-
Anthony, D.C.1
Miller, K.M.2
Fearn, S.3
Townsend, M.J.4
Opdenakker, G.5
Wells, G.M.A.6
Clements, J.M.7
Chandler, S.8
Gearing, A.J.H.9
Perry, V.H.10
-
38
-
-
82155168545
-
The acute inflammatory response to intranigral alpha-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation
-
Couch, Y., Alvarez-Erviti, L., Sibson, N. R., Wood, M. J. A. & Anthony, D. C. The acute inflammatory response to intranigral alpha-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation. J. Neuroinflammation 8, 166 (2011).
-
(2011)
J. Neuroinflammation
, vol.8
, pp. 166
-
-
Couch, Y.1
Alvarez-Erviti, L.2
Sibson, N.R.3
Wood, M.J.A.4
Anthony, D.C.5
|