Neuroprotective effect of chebulagic acid via autophagy induction in SH-SY5Y cells

Biomolecules and Therapeutics

Volumn 22, Issue 4, 2014, Pages 275-281

  Kim, Hee Ju ^a,b   Kim, Joonki ^a   Kang, Ki Sung ^a   Lee, Keun Taik ^b   Yang, Hyun Ok ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Gangneung Wonju National University   (South Korea)

Author keywords

Autophagy; Chebulagic acid; Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; BECLIN 1; CELL PROTEIN; CHEBULAGIC ACID; GOLGI ASSOCIATED ATPASE ENHANCER OF 16 KDA PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LIGHT CHAIN 3 II PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN DOR; PROTEIN TP53INP2; UNCLASSIFIED DRUG;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL STRAIN; CELL STRAIN SH SY5Y; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NEUROPROTECTION; PARKINSON DISEASE; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; SYMPTOM;

EID: 84905235799     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2014.068     Document Type: Article

References (39)

1. Bae, N. Y., Ahn, T. K., Chung, S. K., Oh, M. S., Ko, H. S., Oh, H. G., Park, G. H. and Yang, H. O. (2011) The neuroprotective effect of modified Yeoldahanso-tang via autophagy enhancement in models of Parkinson's disease. J. Ethnopharmacol. 134, 313-322.
2. Baliga, M. S. and Dsouza, J. J. (2011) Amla(Emblica officinalis Gaertn), a wonder berry in the treatment and prevention of cancer. Eur. J. Cancer Prev. 20, 225-239.
3. Bao, X. X., Xie, B. S., Li, Q., Li, X. P., Wei, L. H. and Wang, J. L. (2012) Nifedipine induced autophagy through Beclin1 and mTOR pathway in endometrial carcinoma cells. Chin. Med. J. 125, 3120-3126
4. Bollimuntha, S., Singh, B. B. and Shavali, S. (2005) TRPC1-mediated inhibition of 1-methyl-4-phenylpyridinium ion neurotoxicity in human SH-SY5Y neuroblastoma cells. J. Biol. Chem. 280, 2132-2140.
5. Chang, C. L. and Lin, C. S. (2012) Phytochemical composition, antioxidant activity, and neuroprotective effect of Terminalia chebula Retzius extracts. Evid. Based Complement. Alternat. Med. 2012, 125247.
6. +-induced apoptosis in SH-SY5Y cells. J. Neural Transm. 110, 835-845.
7. Chen, Z., Lu, T., Yue, X., Wei, N., Jiang, Y., Chen, M., Ni, G., Liu, X. and Xu, G. (2010) Neuroprotective effect of ginsenoside Rb1 on glutamate-induced neurotoicity: With emphasis on autophagy. Neurosci. Lett. 482, 264-268.
8. Choi, J. Y., Jang, E. H., Park, C. S. and Kang, J. H. (2005) Enhanced susceptibility to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine neurotoxicity in high-fat diet induced obesity. Free Radic. Biol. Med. 38, 806-816.
9. Dadakhujaev, S., Noh, H. S., Jung, E. J., Cha, J. Y., Baek, S. M., Ha, J. H. and Kim, D. R. (2010) Autophagy protects the rotenone-induced cell death in alpha-synuclein overexpressing SH-SY5Y cells. Neurosci. Lett. 472, 47-52.
10. Dauer, W. and Przedborski, S. (2003) Parkinson's disease: mechanisms and models. Neuron 39, 889-909.
11. Gurusamy, N., Lekli, I., Mukherjee, S., Ray, D., Ahsan, K., Gherghiceanu, M., Popescu, L. M. and Das, D. K. (2010) Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway. Cardiovasc. Res. 86, 103-112.
12. Hara, T., Nakamura, K., Matsui, M., Yamamoto, A., Nakahara, Y., Suzuki-Migishima, R., Yokoyama, M., Mishima, K., Ichiro, S., Okano, H. and Mizushima, N. (2006) Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441, 885-889.
13. Han, J., Pan, X. Y., Xu, Y., Xiao, Y., An, Y., Tie, L., Pan, Y. and Li, X. J. (2012) Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage. Autophagy 8, 812-825.
14. Hay, N. and Sonenberg, N. (2004) Upstream and downstream of mTOR. Genes Dev. 18, 1926-1945.
15. Kabeya, Y., Mizushima, N., Yamamoto, A., Satsuki, O. O., Ohsumi, Y. and Yoshimori, T. (2004) LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. J. Cell Sci. 117, 2805-2812.
16. Ko, H. S., Kim, Y. J., Amor, E. C., Lee, J. W., Kim, H. C., Kim, H. J. and Yang, H. O. (2011) Induction of autophagy by dimethyl cardamonin is associated with proliferative arrest in human colorectal carcinoma HCT116 and LOVO cells. J. Cell. Biochem. 112, 2471-2479.
17. Larsen, K. E. and Sulzer, D. (2002) Autophagy in neurons: a review. Histol. Histopathol. 17, 897-908.
18. Liang, J., Shao, S. H., Xu, Z. X., Hennessy, B., Ding, Z., Larrea, M., Kondo, S., Dumont, D. J., Gutterman, J. U., Walker, C. L., Slingerland, J. M. and Mills, G. B. (2007) The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis. Nat. Cell. Biol. 9, 218-224.
19. Liu, D., Si, H., Reynolds, K. A., Zhen, W., Jia, Z. and Dillon, J. S. (2007) Dehydroepiandrosterone protects vascular endothelial cells against apoptosis through a Galphai protein-dependent activation of phosphatidylinositol 3-kinase/Akt and regulation of antiapoptotic Bcl-2 expression. Endocrinology 148, 3068-3076.
20. +-induced neurotoxicity in SH-SY5Y cells. Brain Res. 1003, 86-97.
21. Mauvezin, C., Orpinell, M., Francis, V. A., Mansilla, F., Duran, J., Ribas, V., Palacín, M., Boya, P., Teleman, A. A. and Zorzano, A. (2010) The nuclear cofactor DOR regulates autophagy in mammalian and Drosophila cells. EMBO Rep. 11, 37-44.
22. Melendez, A., Talloczy, Z., Seaman, M., Eskelinen, E. L., Hall, D. H. and Levine, B. (2003) Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301, 1387-1391.
23. Nowak, J., Archange, C., Joel, T. L., Pontarotti, P., Pébusque, M., Vaccaro, M. I., Velasco, G., Dagorn, J. C. and Iovanna, J. L. (2009) The TP53INP2 protein is required for autophagy in mammalian cells. Mol. Biol. Cell 20, 870-881.
24. Nowak, J. and Iovanna, J. L. (2009) TP53INP2 is the new guest at the table of self-eating. Autophagy 5, 383-384.
25. Pan, T., Kondo, S., Le, W. and Jankovic, J. (2008a) The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease. Brain 131, 1969-1978.
26. Pan, T., Kondo, S., Zhu, W., Xie, W., Jankovic, J. and Le, W. (2008b) Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement. Neurobiol. Dis. 32, 16-25.
27. Pan, T., Rawal, P., Wu, Y., Xie, W., Jankovic, J. and Le, W. (2009) Rapamycin protects against rotenone-induced apoptosis through autophagy induction. Neuroscience 164, 541-551.
28. Park, J. H., Joo, H. S., Yoo, K. Y., Shin, B. N., Kim, I. H., Lee, C. H., Choi, J. H., Byun, K., Lee, B., Lim, S. S., Kim, M. J. and Won, M. H. (2011) Extract from Terminalia chebula seeds protect against experimental ischemic neuronal damage via maintaining SODs and BDNF levels. Neurochem. Res. 36, 2043-2050.
29. Patschan, S., Chen, J. and Polotskaia, A. (2008) Lipid mediators of autophagy in stressinduced premature senescence of endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 294, 1119-1129.
30. Per, O. S. and Paul, B. G. (1982) 3-methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc. Nati. Acad. Sci. U.S.A. 79, 1889-1892.
31. Ravikumar, B., Berger, Z., Vacher, C., O'Kane, C. J. and Rubinsztein, D. C. (2006) Rapamycin pre-treatment protects against apoptosis. Hum. Mol. Genet. 15, 1209-1216.
32. Shin, H. Y., Chu, S. H., Lee, H. K. and Lee, J. W. (2011) mTOR inhibitor as a potential drug of age-related disease. Korean. J. Clin. Geri. 12, 149-159.
33. Spowart, J. and Lum, J. J. (2010) Opening a new DOR to autophagy. EMBO. Rep. 11, 4-5.
34. Tanida, I., Ueno, T. and Kominami, E. (2004) LC3 conjugation system in mammalian autophagy. Int. J. Biochem. Cell Biol. 36, 2503-2518.
35. Underwood, B. R., Imarisio, S., Fleming, A., Rose, C., Krishna, G., Heard, P., Quick, M., Korolchuk, V. I., Renna, M., Sarkar, S., García-Arencibia, M., O'Kane, C. J., Murphy, M. P. and Rubinsztein, D. C. (2010) Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease. Hum. Mol. Genet. 19, 3413-3429.
36. +: partial protection of PC12 cells by acetyl-L-carnitine. Ann. N. Y. Acad. Sci. 1025, 267-273.
37. Weidberg, H., Shvets, E., Shpilka, T., Shimron, F., Shinder, V. and Elazar, Z. (2010) LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis. EMBO J. 29, 1792-1802.
38. Williams, T., Forsberg, L. J., Viollet, B. and Brenman, J. E. (2009) Basal autophagy induction without AMP-activated protein kinase under low glucose conditions. Autophagy 5, 1155-1165.
39. Wu, Y., Li, X., Zhu, J. X., Xie, W., Le, W., Fan, Z., Jankovic, J. and Pan, T. (2011) Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease. Neurosignals 19, 163-174.