메뉴 건너뛰기




Volumn 482, Issue 3, 2010, Pages 264-268

Neuroprotective effect of ginsenoside Rb1 on glutamate-induced neurotoxicity: With emphasis on autophagy

Author keywords

Autophagy; Beclin 1; Ginsenoside Rb1; Glutamate; Neuronal cell death

Indexed keywords

3 METHYLADENINE; BECLIN 1; CELL PROTEIN; GINSENOSIDE RB 1; GLUTAMIC ACID; PROTEIN LC3; UNCLASSIFIED DRUG;

EID: 77955924177     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.07.052     Document Type: Article
Times cited : (65)

References (32)
  • 1
    • 36749012387 scopus 로고    scopus 로고
    • The NMDA receptor/ion channel complex: a drug target for modulating synaptic plasticity and excitotoxicity
    • Albensi B.C. The NMDA receptor/ion channel complex: a drug target for modulating synaptic plasticity and excitotoxicity. Curr. Pharm. Des. 2007, 13:3185-3194.
    • (2007) Curr. Pharm. Des. , vol.13 , pp. 3185-3194
    • Albensi, B.C.1
  • 2
    • 68349151350 scopus 로고    scopus 로고
    • A novel protein complex in membrane rafts linking the NR2B glutamate receptor and autophagy is disrupted following traumatic brain injury
    • Bigford G.E., Alonso O.F., Dietrich D., Keane R.W. A novel protein complex in membrane rafts linking the NR2B glutamate receptor and autophagy is disrupted following traumatic brain injury. J. Neurotrauma 2009, 26:703-720.
    • (2009) J. Neurotrauma , vol.26 , pp. 703-720
    • Bigford, G.E.1    Alonso, O.F.2    Dietrich, D.3    Keane, R.W.4
  • 3
    • 0028971863 scopus 로고
    • N-methyl-d-aspartate-mediated or glutamate-mediated toxicity in cultured rat cortical neurons is antagonized by FPL-15896AR
    • Black M.A., Tremblay R., Mealing G., Ray R., Durkin J.P., Whitfield J.F., Blosser J., Morley P. N-methyl-d-aspartate-mediated or glutamate-mediated toxicity in cultured rat cortical neurons is antagonized by FPL-15896AR. J. Neurochem. 1995, 65:2170-2177.
    • (1995) J. Neurochem. , vol.65 , pp. 2170-2177
    • Black, M.A.1    Tremblay, R.2    Mealing, G.3    Ray, R.4    Durkin, J.P.5    Whitfield, J.F.6    Blosser, J.7    Morley, P.8
  • 4
    • 71549151931 scopus 로고    scopus 로고
    • Glutamate, excitotoxicity, and programmed cell death in parkinson disease
    • Caudle W.M., Zhang J. Glutamate, excitotoxicity, and programmed cell death in parkinson disease. Exp. Neurol. 2009, 220:230-233.
    • (2009) Exp. Neurol. , vol.220 , pp. 230-233
    • Caudle, W.M.1    Zhang, J.2
  • 5
    • 11844268081 scopus 로고    scopus 로고
    • Ginsenoside Rg1 reduces MPTP-induced substantia nigra neuron loss by suppressing oxidative stress
    • Chen X.C, Zhou Y.C., Chen Y., Zhu Y.G., Fang F., Chen L.M. Ginsenoside Rg1 reduces MPTP-induced substantia nigra neuron loss by suppressing oxidative stress. Acta Pharmacol. Sinica 2005, 26:56-62.
    • (2005) Acta Pharmacol. Sinica , vol.26 , pp. 56-62
    • Chen, X.C.1    Zhou, Y.C.2    Chen, Y.3    Zhu, Y.G.4    Fang, F.5    Chen, L.M.6
  • 6
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi D.W. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1988, 1:623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 7
    • 13944261588 scopus 로고    scopus 로고
    • Neurodegeneration: cellular defences destroyed
    • Choi D.W. Neurodegeneration: cellular defences destroyed. Nature 2005, 433:696-698.
    • (2005) Nature , vol.433 , pp. 696-698
    • Choi, D.W.1
  • 8
    • 33748424981 scopus 로고    scopus 로고
    • Protective effect of autophagy in anoxia-reoxygenation of isolated cardiomyocyte?
    • Dosenko V.E., Nagibin V.S., Tumanovska L.V., Moibenko A.A. Protective effect of autophagy in anoxia-reoxygenation of isolated cardiomyocyte?. Autophagy 2006, 2:305-306.
    • (2006) Autophagy , vol.2 , pp. 305-306
    • Dosenko, V.E.1    Nagibin, V.S.2    Tumanovska, L.V.3    Moibenko, A.A.4
  • 9
    • 0842328798 scopus 로고    scopus 로고
    • Roles of mitochondria in health and disease
    • Duchen M.R. Roles of mitochondria in health and disease. Diabetes 2004, 53(Suppl. 1):S96-S102.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Duchen, M.R.1
  • 10
    • 34047100940 scopus 로고    scopus 로고
    • N-methyl-d-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease
    • Fan M.M., Raymond L.A. n-methyl-d-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease. Prog. Neurobiol. 2007, 81:272-293.
    • (2007) Prog. Neurobiol. , vol.81 , pp. 272-293
    • Fan, M.M.1    Raymond, L.A.2
  • 13
    • 3042693940 scopus 로고    scopus 로고
    • Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease
    • Hynd M.R, Scott H.L., Dodd P.R. Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease. Neurochem. Int. 2004, 45:583-595.
    • (2004) Neurochem. Int. , vol.45 , pp. 583-595
    • Hynd, M.R.1    Scott, H.L.2    Dodd, P.R.3
  • 14
    • 65249104617 scopus 로고    scopus 로고
    • The role of autophagy in spinal cord injury
    • Kanno H., Ozawa H., Sekiguchi A., Itoi E. The role of autophagy in spinal cord injury. Autophagy 2009, 5:390-392.
    • (2009) Autophagy , vol.5 , pp. 390-392
    • Kanno, H.1    Ozawa, H.2    Sekiguchi, A.3    Itoi, E.4
  • 16
    • 0031596324 scopus 로고    scopus 로고
    • Ginsenosides Rb1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration
    • Kim Y.C., Kim S.R., Markelonis G.J., Oh T.H. Ginsenosides Rb1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration. J. Neurosci. Res. 1998, 53:426-432.
    • (1998) J. Neurosci. Res. , vol.53 , pp. 426-432
    • Kim, Y.C.1    Kim, S.R.2    Markelonis, G.J.3    Oh, T.H.4
  • 17
    • 34248583762 scopus 로고    scopus 로고
    • Methods for monitoring autophagy from yeast to human
    • Klionsky D.J., Cuervo A.M., Seglen P.O. Methods for monitoring autophagy from yeast to human. Autophagy 2007, 3:181-206.
    • (2007) Autophagy , vol.3 , pp. 181-206
    • Klionsky, D.J.1    Cuervo, A.M.2    Seglen, P.O.3
  • 19
    • 37649005234 scopus 로고    scopus 로고
    • Autophagy in the pathogenesis of disease
    • Levine B., Kroemer G. Autophagy in the pathogenesis of disease. Cell 2008, 132:27-42.
    • (2008) Cell , vol.132 , pp. 27-42
    • Levine, B.1    Kroemer, G.2
  • 20
    • 0036180097 scopus 로고    scopus 로고
    • Neuroprotective effects of ginseng total saponin and ginsenosides Rb1 and Rg1 on spinal cord neurons in vitro
    • Liao B.S., Newmark H., Zhou R.P. Neuroprotective effects of ginseng total saponin and ginsenosides Rb1 and Rg1 on spinal cord neurons in vitro. Exp. Neurol. 2002, 173:224-234.
    • (2002) Exp. Neurol. , vol.173 , pp. 224-234
    • Liao, B.S.1    Newmark, H.2    Zhou, R.P.3
  • 21
    • 0031570787 scopus 로고    scopus 로고
    • Glutamate-treated rat cortical neuronal cultures die in a way different from the classical apoptosis induced by staurosporine
    • MacManus J.P., Rasquinha I., Black M.A., Laferriere N.B., Monette R., Walker T., Morley P. Glutamate-treated rat cortical neuronal cultures die in a way different from the classical apoptosis induced by staurosporine. Exp. Cell Res. 1997, 233:310-320.
    • (1997) Exp. Cell Res. , vol.233 , pp. 310-320
    • MacManus, J.P.1    Rasquinha, I.2    Black, M.A.3    Laferriere, N.B.4    Monette, R.5    Walker, T.6    Morley, P.7
  • 22
    • 0037087625 scopus 로고    scopus 로고
    • The polychlorinated biphenyl mixture aroclor 1254 induces death of rat cerebellar granule cells: the involvement of the n-methyl-d-aspartate receptor and reactive oxygen species
    • Mariussen E., Myhre O., Reistad T., Fonnum F. The polychlorinated biphenyl mixture aroclor 1254 induces death of rat cerebellar granule cells: the involvement of the n-methyl-d-aspartate receptor and reactive oxygen species. Toxicol. Appl. Pharmacol. 2002, 179:137-144.
    • (2002) Toxicol. Appl. Pharmacol. , vol.179 , pp. 137-144
    • Mariussen, E.1    Myhre, O.2    Reistad, T.3    Fonnum, F.4
  • 23
    • 34147168105 scopus 로고    scopus 로고
    • Distinct roles of autophagy in the heart during ischemia and reperfusion-Roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy
    • Matsui Y., Takagi H., Qu X.P., Abdellatif M., Sakoda H., Asano T., Levine B., Sadoshima J. Distinct roles of autophagy in the heart during ischemia and reperfusion-Roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy. Circ. Res. 2007, 100:914-922.
    • (2007) Circ. Res. , vol.100 , pp. 914-922
    • Matsui, Y.1    Takagi, H.2    Qu, X.P.3    Abdellatif, M.4    Sakoda, H.5    Asano, T.6    Levine, B.7    Sadoshima, J.8
  • 24
    • 27644495684 scopus 로고    scopus 로고
    • Autophagic degeneration of motor neurons in a model of slow glutamate excitotoxicity in vitro
    • Matyja E., Taraszewska A., Naganska E., Rafalowska J. Autophagic degeneration of motor neurons in a model of slow glutamate excitotoxicity in vitro. Ultrastruct. Pathol. 2005, 29:331-339.
    • (2005) Ultrastruct. Pathol. , vol.29 , pp. 331-339
    • Matyja, E.1    Taraszewska, A.2    Naganska, E.3    Rafalowska, J.4
  • 25
    • 1842767259 scopus 로고    scopus 로고
    • Mitochondrial regulation of apoptotic cell death
    • Orrenius S. Mitochondrial regulation of apoptotic cell death. Toxicol. Lett. 2004, 149:19-23.
    • (2004) Toxicol. Lett. , vol.149 , pp. 19-23
    • Orrenius, S.1
  • 27
  • 28
    • 4344622460 scopus 로고    scopus 로고
    • Ginsenosides Rb-1 and Rg(1) effects on mesencephalic dopaminergic cells stressed with glutamate
    • Radad K., Gille G., Moldzio R., Saito H., Rausch W.D. Ginsenosides Rb-1 and Rg(1) effects on mesencephalic dopaminergic cells stressed with glutamate. Brain Res. 2004, 1021:41-53.
    • (2004) Brain Res. , vol.1021 , pp. 41-53
    • Radad, K.1    Gille, G.2    Moldzio, R.3    Saito, H.4    Rausch, W.D.5
  • 29
    • 0034688312 scopus 로고    scopus 로고
    • Glutamate release in severe brain ischaemia is mainly by reversed uptake
    • Rossi D.J., Oshima T., Attwell D. Glutamate release in severe brain ischaemia is mainly by reversed uptake. Nature 2000, 403:316-321.
    • (2000) Nature , vol.403 , pp. 316-321
    • Rossi, D.J.1    Oshima, T.2    Attwell, D.3
  • 31
    • 34247186472 scopus 로고    scopus 로고
    • Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
    • Scherz-Shouval R., Shvets E., Fass E., Shorer H., Gil L., Elazar Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J. 2007, 26:1749-1760.
    • (2007) EMBO J. , vol.26 , pp. 1749-1760
    • Scherz-Shouval, R.1    Shvets, E.2    Fass, E.3    Shorer, H.4    Gil, L.5    Elazar, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.