Multicapillary SDS-gel electrophoresis for the analysis of fluorescently labeled mAb preparations: A high throughput quality control process for the production of QuantiPlasma and PlasmaScan mAb libraries

Electrophoresis

Volumn 35, Issue 15, 2014, Pages 2155-2162

  Székely, Andrea ^a   Szekrényes, Ákos ^b   Kerékgyártó, Márta ^b   Balogh, Attila ^a   Kádas, János ^a,b   Lázár, József ^a   Guttman, András ^b,c   Kurucz, István ^a   Takács, László ^a,b  

^a Biosystems International Kft   (Hungary)

^b UNIVERSITY OF DEBRECEN   (Hungary)

^c UNIVERSITY OF PANNONIA   (Hungary)

Author keywords

Capillary electrophoresis; Glycoform; MAb proteomics; Quality control; SDS

Indexed keywords

LIBRARIES; MOLECULAR BIOLOGY; PROCESS CONTROL; QUALITY ASSURANCE; THROUGHPUT;

CONTROL PROCESS; GEL ELECTROPHORESIS; GLYCOFORMS; HIGH-THROUGHPUT; MAB PROTEOMIC; MOLECULAR HETEROGENEITY; MULTICAPILLARIES; POST-TRANSLATIONAL MODIFICATIONS; PROTEOMICS; SDS;

CAPILLARY ELECTROPHORESIS;

IMMUNOGLOBULIN G ANTIBODY; MONOCLONAL ANTIBODY; FLUORESCENT DYE; GLYCOPROTEIN; PEPTIDE LIBRARY; QUANTISON DEPOT; SERUM ALBUMIN;

ANALYTICAL EQUIPMENT; ANTIBODY LABELING; ANTIBODY LIBRARY; ANTIBODY PRODUCTION; ARTICLE; CAPILLARY ELECTROPHORESIS; CONTROLLED STUDY; FLUORESCENT ANTIBODY TECHNIQUE; HIGH THROUGHPUT SCREENING; LIGHT EMITTING DIODE; MULTICAPILLARY SDS GEL ELECTROPHORESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROCESS DEVELOPMENT; PROTEIN PROCESSING; PROTEOMICS; QUALITY CONTROL; CHEMISTRY; HUMAN; PEPTIDE LIBRARY; PROCEDURES; STANDARDS;

ANTIBODIES, MONOCLONAL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FLUORESCENT DYES; GLYCOPROTEINS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; PEPTIDE LIBRARY; QUALITY CONTROL; SERUM ALBUMIN;

EID: 84905197384     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201400208     Document Type: Article

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