Variable domain-linked oligosaccharides of a human monoclonal IgG: Structure and influence on antigen binding

Biochemical Journal

Volumn 338, Issue 2, 1999, Pages 529-538

  Leibiger, Haike ^a   Wüstner, Daniel ^a   Stigler, Rolf Dietrich ^a   Marx, Uwe ^a,b  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Antibody; Carbohydrate; CHARMm; Energy minimization; Fluorophore assisted carbohydrate electrophoresis

Indexed keywords

CARBOHYDRATE; GLYCOSIDASE; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN; N ACETYLNEURAMINIC ACID; N GLYCOLOYLNEURAMINIC ACID; OLIGOSACCHARIDE;

ANION EXCHANGE CHROMATOGRAPHY; ANTIBODY STRUCTURE; ANTIGEN BINDING; ARTICLE; CONSENSUS SEQUENCE; DEGLYCOSYLATION; ELECTROPHORESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GLYCOSYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ANTIGEN-ANTIBODY REACTIONS; ANTIGENS; BASE SEQUENCE; CARBOHYDRATE SEQUENCE; DNA PRIMERS; HUMANS; IMMUNOGLOBULIN G; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGOSACCHARIDES; PROTEIN CONFORMATION;

EID: 0039725069     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3380529     Document Type: Article

References (51)

1. Donadel, G., Calabro, A., Sigounas, G., Hascall, V. C., Notkins, A. L. and Harindranath, N. (1994) Glycobiology 4, 491-496
2. Leung, S., Goldenberg, D. M., Dion, A. S., Pellegrini, M. C., Shevitz, J., Shih, L. B. and Hansen, H. J. (1995) Mol. Immunol. 32, 1413-1427
3. Khurana, S., Raghunathan, V. and Salunke, D. M. (1997) Biochem. Biophys. Res. Commun. 234, 465-469
4. Spiegelberg, H. L., Abel, C. A., Fishkin, B. G. and Grey, H. M. (1970) Biochemistry 9, 4217-4223
5. Sox, H. C. and Hood, L. (1970) Proc. Natl. Acad. Sci. U.S.A. 66, 975-982
6. Decourt, C., Cogne, M. and Rocca, A. (1996) Clin. Exp. Immunol. 106, 357-361
7. Wallik, S. C., Kabat, E. A. and Morrison, S. L. (1988) J. Exp. Med. 168, 1099-1109
8. Wright, A., Tao, M., Kabat, A. E. and Morrison, S. L. (1991) EMBO J. 10, 2717-2723
9. Rademacher, T. W., Homans, S. W., Parekh, R. B. and Dwek, R. A. (1988) Biochem. Soc. Symp. 51, 131-138
10. Savidou, G., Klein, M., Grey, A. A., Dorrington, K. J. and Carver, J. P. (1984) Biochemistry 23, 3736-3740
11. Tachibana, H., Kim, Y. Y. and Shirahata, S. (1997) Cytotechnology 23, 151-159
12. Chandrasekaran, E. V., Mendicino, A., Garver, F. A. and Mendicino, J. (1981) J. Biol. Chem. 256, 1549-1555
13. Middaugh, C. R. and Litman, G. W. (1987) J. Biol. Chem. 262, 3671-3673
14. Holm, E., Sletten, K. and Husby, G. (1986) Biochem. J. 239, 545-552
15. Fykse, E. M., Sletten, K., Husby, G. and Cornwell, G. G. (1988) Biochem. J. 256, 973-980
16. Brooks, B. R., Bruccoleri, R. E., Olafson, B. D., States, D. J., Swaminathan, S. and Karplus, M. (1983) J. Comput. Chem. 4, 187-217
17. Kouwijzer, M. L. C. E. and Grootenhuis, P. D. J. (1995) J. Phys. Chem. 99, 13426-13436
18. Leibiger, H., Hansen, A., Schoenherr, G., Seifert, M., Wüstner, D., Stigler, R. and Marx, U. (1995) Mol. Immunol. 32, 595-602
19. Sambrook, J., Fritsch, E. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, vols. 1-3, Cold Spring Harbor Press, Cold Spring Harbor
20. Marks, J. D., Tristem, M., Karpas, A. and Winter, G. (1991) Eur. J. Immunol. 21, 985-992
21. Songsviali, S., Bye, J. M., Marks, J. D. and Hughes-Jones, N. C. (1990) Eur. J. Immunol. 20, 2661-2666
22. Sanger, F., Nicklen, S. and Coulson, A. R. (1977) Proc. Natl. Acad. Sci. U.S.A. 74, 5463-5471
23. Leibiger, H., Kersten, B., Albersheim, P. and Darvill, A. (1998) Glycobiology 8, 497-507
24. Needleman, S. B. and Wunch, C. O. (1970) J. Mol. Biol. 48, 443-453
25. Dayhoff, M. O. (1978) Atlas of Protein Sequence and Structure, vol. 5, suppl. 3, Biomedical Research Foundation, Silver Spring
26. Bernstein, F. C., Koetzle, T. F., Williams, G. J. B., Meyer, Jr., E. F., Brice, M. D., Rodgers, J. R., Kennard, O., Shimanouchi, T. and Tasumi, M. (1977) J. Mol. Biol. 112, 535-542
27. Kratzin, H. D, Palm, W., Stangel, M., Schmidt, W. E, Friedrich, J. and Hilschmann, N. (1989) Biol. Chem. Hoppe-Seyler 370, 263-272
28. Lolis, E., Alber, T., Davenport, R. C., Rose, D., Hartman, F. C. and Petsko, G. A. (1990) Biochemistry 29, 6609-6618
29. Min He, X., Rüker, F., Casale, E. and Carter, D. C. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 7154-7158
30. Jorgensen, W. L. and Ibrahim, M. (1981) J. Am. Chem. Soc. 103, 3976-3985
31. Kabat, E. A., Wu, T. T., Reid-Miller, M., Rerry, H. M. and Gottesmann, K. S. (1991) Sequences of Proteins of Immunological Interest, 5th edn., US Department of Health and Human Services, National Institutes of Health, Bethesda
32. Connolly, M. L. (1983) J. Appl. Crystallogr. 16, 548-558
33. Lee, B. and Richards, F. M. (1971) J. Mol. Biol. 55, 379-400
34. Abagyan, R., Totrov, M. and Kuznetsov, D. (1994) J. Comput. Chem. 15, 488-506
35. Zauhar, R. J. and Morgan, R. S. (1985) J. Mol. Biol. 186, 815-820
36. Kinoshita, N., Ohno, M., Nishiura, T., Fujii, S., Nishikawa, A., Kawakami, Y., Uozumi, N. and Taniguchi, N. (1991) Cancer Res. 51, 5888-5892
37. Coco-Martin, J. M., Brunik, F., Van Der Velden De Groot, T. A. M. and Beuyvery, E. C. (1992) J. Immunol. Methods 155, 241-248
38. Muchmore, E. A., Milewski, M., Varki, A. and Diaz, S. (1989) J. Biol. Chem. 264, 20216-20223
39. Monica, T. J., Williams, S. B., Gochee, C. F. and Maiorella, B. L. (1995) Glycobiology 5, 175-185
40. Tandai, M., Endo, T., Sasaki, S., Masuho, Y., Kochibe, N. and Kobata, A. (1991) Arch. Biochem. Biophys. 231, 339-348
41. Noguchi, A., Mukuria, C. J., Suzuki, E. and Naiki, M. (1995) J. Biochem. (Tokyo) 117, 59-62
42. Flesher, A. R., Marzowski, J., Wang, W. C. and Raff, H. V. (1995) Biotechnol. Bioeng. 46, 399-407
43. Kato, M., Mochizuki, K., Hashizume, S., Tachibana, H., Shirahata, S. and Murakami, H. (1993) Hum. Antibodies Hybridomas 4, 9-14
44. Rosenstein, R. W., Musson, R., Armstrong, M., Konigsberg, W. H. and Richards, F. (1972) Proc. Natl. Acad. Sci. U.S.A. 69, 877-881
45. Avrameas, S. and Ternyck, T. (1993) Mol. Immunol. 30, 1133-1142
46. Casali, P. and Notkins, A. L. (1989) Annu. Rev. Immunol. 7, 513-525
47. Adib-Conouy, M., Avrameas, S. and Ternyck, T. (1993) Mol. Immunol. 30, 119-127
48. Rutherford, T. J., Partridge, J., Weller, C. T. and Homans, S. W. (1993) Biochemistry 32, 12715-12724
49. Rutherford, T. J. and Homans, S. W. (1994) Biochemistry 33, 9606-9614
50. Rutherford, T. J., Neville, D. C. and Homans, S. W. (1995) Biochemistry 34, 14131-14137
51. Sato, K., Ohtomo, T., Saito, H., Matsuura, T., Akimoto, T., Akamatsu, K. I., Koishihara, Y., Ohsugai, Y. and Tsuchiya, M. (1996) Hum. Antibodies Hybridomas 7, 175-183