Simultaneous determination of ezetimibe and simvastatin in rat plasma by stable-isotope dilution LC-ESI-MS/MS and its application to a pharmacokinetic study

Journal of Pharmaceutical Analysis

Volumn 4, Issue 4, 2014, Pages 286-294

  Karanam, Sireesha R ^a   Katakam, Prakash ^b   Chandu, Babu R ^b   Hwisa, Nagiat T ^b   Adiki, Shanta K ^b,c  

^a Vimta Life Sciences   (India)

^b UNIVERSITY OF ZAWIA   (Libyan Arab Jamahiriya)

^c NIRMALA COLLEGE OF PHARMACY   (India)

Author keywords

Ezetimibe; LC ESI MS MS; Pharmacokinetics; Rat plasma; Simvastatin

Indexed keywords

ACETONITRILE; AMMONIUM ACETATE; EZETIMIBE; SIMVASTATIN; TERT BUTYL METHYL ETHER;

ACCURACY; ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOEQUIVALENCE; DRUG BIOAVAILABILITY; DRUG DETERMINATION; ISOTOPE DILUTION ASSAY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; RAT;

EID: 84905184032     PISSN: 20951779     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpha.2013.08.002     Document Type: Article

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