Pharmacodynamic interaction between the new selective cholesterol absorption inhibitor ezetimibe and simvastatin

British Journal of Clinical Pharmacology

Volumn 54, Issue 3, 2002, Pages 309-319

  Kosoglou, Teddy ^a   Meyer, Ingo ^b   Veltri, Enrico P ^a   Statkevich, Paul ^a   Yang, Bo ^a   Zhu, Yali ^a   Mellars, Lillian ^a   Maxwell, Stephen E ^a   Patrick, James E ^a   Cutler, David L ^a   Batra, Vijay K ^a   Affrime, Melton B ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b IQVIA   (United States)

Author keywords

Cholesterol absorption inhibitor; Drug interaction; Ezetimibe; Hypercholesterolaemia; Pharmacodynamics; Pharmacokinetics; Simvastatin

Indexed keywords

EZETIMIBE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYPOCHOLESTEROLEMIC AGENT; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; SIMVASTATIN; TRIACYLGLYCEROL;

ADULT; ARTICLE; BLOOD SAMPLING; CHOLESTEROL BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERANCE; HUMAN; HUMAN EXPERIMENT; LIPID BLOOD LEVEL; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; SINGLE BLIND PROCEDURE; STATISTICAL ANALYSIS;

ADMINISTRATION, ORAL; ADULT; ANTICHOLESTEREMIC AGENTS; AZETIDINES; BIOLOGICAL AVAILABILITY; BODY MASS INDEX; CHOLESTEROL, LDL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG INTERACTIONS; HUMANS; MALE; MIDDLE AGED; SIMVASTATIN;

EID: 18544390238     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2002.01633.x     Document Type: Article

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