Dual blockade of the A1 and A2A adenosine receptor prevents amyloid beta toxicity in neuroblastoma cells exposed to aluminum chloride

International Journal of Biochemistry and Cell Biology

Volumn 54, Issue , 2014, Pages 122-136

  Giunta, Salvatore ^a   Andriolo, Violetta ^b   Castorina, Alessandro ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

Author keywords

Adenosine receptor; Aluminum; Alzheimer's disease; Caffein; Neurotoxicity

Indexed keywords

5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ACETYLCYSTEINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ALUMINUM CHLORIDE; AMYLOID BETA PROTEIN[25-35]; AMYLOID PRECURSOR PROTEIN; ANTIOXIDANT; BETA SECRETASE 1; CAFFEINE; DEFEROXAMINE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; ADENOSINE A2 RECEPTOR; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; I KAPPA B ALPHA; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; NEUROPROTECTIVE AGENT; PROTEIN BAX; PROTEIN BCL 2; TRANSCRIPTION FACTOR RELA; 1,3-DIPROPYL-8-CYCLOPENTYLXANTHINE; 5-AMINO-7-(2-PHENYLETHYL)-2-(2-FURYL)PYRAZOLO(4,3-E)-1,2,4-TRIAZOLO(1,5-C)PYRIMIDINE; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2 RECEPTOR ANTAGONIST; ADENOSINE RECEPTOR BLOCKING AGENT; ALUMINUM DERIVATIVE; AMYLOID BETA PROTEIN; ASTRINGENT AGENT; CHLORIDE; PYRIMIDINE DERIVATIVE; TRIAZOLE DERIVATIVE; XANTHINE DERIVATIVE;

APOPTOSIS; ARTICLE; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DISEASE COURSE; DRUG MECHANISM; ENVIRONMENTAL EXPOSURE; GENE SILENCING; HUMAN; HUMAN CELL; LIPID PEROXIDATION; NERVE CELL CULTURE; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; OXIDATIVE STRESS; PROTEIN EXPRESSION; RECEPTOR BLOCKING; ALZHEIMER DISEASE; ANTIOXIDANT ACTIVITY; CELL DAMAGE; CELL DEATH; CELL PROLIFERATION; CYTOSOL; DOSE RESPONSE; NEUROBLASTOMA CELL LINE; PROTEIN PHOSPHORYLATION; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; GENETICS; METABOLISM; NEUROBLASTOMA; PATHOLOGY; WESTERN BLOTTING;

ADENOSINE A1 RECEPTOR ANTAGONISTS; ADENOSINE A2 RECEPTOR ANTAGONISTS; ALUMINUM COMPOUNDS; AMYLOID BETA-PEPTIDES; APOPTOSIS; ASTRINGENTS; BLOTTING, WESTERN; CAFFEINE; CELL PROLIFERATION; CELLS, CULTURED; CHLORIDES; HUMANS; LIPID PEROXIDATION; NEUROBLASTOMA; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; PURINERGIC P1 RECEPTOR ANTAGONISTS; PYRIMIDINES; REACTIVE OXYGEN SPECIES; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2A; RNA, SMALL INTERFERING; TRIAZOLES; XANTHINES;

EID: 84905161640     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2014.07.009     Document Type: Article

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