Reduced folate carrier-1 G80a gene polymorphism is associated with neuroblastoma's development

Molecular Biology Reports

Volumn 41, Issue 8, 2014, Pages 5069-5075

  De Miranda, Dyego O ^a   Barros, Jemima E X S ^a,b   Vieira, Maria Madalena S ^a,c   Lima, Elker L S ^a   Moraes, Vera L L ^a   Da Silva, Helker A ^a,b   Garcia, Helder L B O ^d   Lima, Cássia A ^a,c   Gomes, Adriana V ^a,c   Santos, Neide ^c   Muniz, Maria T C ^a,c  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^b FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^c Universidade de Pernambuco UPE   (Brazil)

^d FUNDAÇÃO GETÚLIO VARGAS   (Brazil)

Author keywords

G80A polymorphism; Neuroblastoma; Reduced Folate Carrier 1; SLC19A1 gene

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); FOLIC ACID; GENOMIC DNA; REDUCED FOLATE CARRIER; REDUCED FOLATE CARRIER 1; UNCLASSIFIED DRUG; CARRIER PROTEIN; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MTHFR PROTEIN, HUMAN; SLC19A2 PROTEIN, HUMAN;

ADOLESCENT; ARTICLE; BRAZILIAN; CANCER RISK; CARCINOGENESIS; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ETHNIC GROUP; FEMALE; FOLATE METABOLISM; GENE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOMIC INSTABILITY; GENOTYPE; HETEROZYGOTE; HUMAN; INFANT; MALE; MTHFR GENE; MTR GENE; NEUROBLASTOMA; NEWBORN; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDY; REDUCED FOLATE CARRIER 1 GENE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RETROSPECTIVE STUDY; SIGNAL TRANSDUCTION; SLC19A1 GENE; TYMS GENE; BRAZIL; CASE CONTROL STUDY; GENETICS; METABOLISM; PRESCHOOL CHILD; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; BRAZIL; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; FEMALE; FOLIC ACID; GENOTYPE; HUMANS; INFANT; INFANT, NEWBORN; MALE; MEMBRANE TRANSPORT PROTEINS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); NEUROBLASTOMA; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84905106648     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-014-3372-6     Document Type: Article

References (42)

1. Brodeur GM (2003) Neuroblastoma: biological insights into a clinical enigma. Nat Rev Cancer 3:203-216
2. Schwab M, Westermann F, Hero B et al (2003) Neuroblastoma: biology and molecular and chromosomal pathology. Lanc Oncol 4:472-480 (Pubitemid 37009955)
3. Lam WA, Cao L, Umesh V et al (2010) Extracellular matrix rigidity modulates neuroblastoma cell differentiation and N-myc expression. Mol Cancer 9:35
4. Gurney JG, Ross JA, Wall DA et al (1997) Infant cancer in the U.S.: histology-specific incidence and trends, 1973 to 1992. J Pediatr Hematol Oncol 19:428-432 (Pubitemid 28076487)
5. Brodeur GM, Maris JM (2002) Neuroblastoma. In: Pizzo PA, Poplack DG (eds) Principles and practice of pediatric oncology, 4th edn. Williams & Wilkins, Philadelphia, pp 865-937
6. Harder T, Plagemann A, Harder A (2010) Birth weight and risk of neuroblastoma: a meta-analysis. Int J Epidemiol 9(39):746-756
7. Bailey LB, Gregory JF (1999) Folate metabolism and requirements. J Nut 129:779-782 (Pubitemid 29162370)
8. Suh JR, Herbig AK, Stover PJ (2001) New perspectives on folate catabolism. Annu Rev Nutr 21:255-282 (Pubitemid 32695272)
9. Doll R (1992) The lessons of life: keynote address to the nutrition and cancer conference. Cancer Res 52:2024-2029
10. French AE, Grant R, Weitzman S et al (2003) Folic acid food fortification is associated with a decline in neuroblastoma. Clin Pharmacol Ther 74(3):288-294 (Pubitemid 37083104)
11. Sharp L, Little J (2004) Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a huge review. Am J Epidemiol 159:423-443 (Pubitemid 38280289)
12. Reeves SG, Meldrum C, Groombridge C et al (2009) MTHFR 677 C>T and 1298 A>C polymorphisms and the age of onset of colorectal cancer in hereditary nonpolyposis colorectal cancer. Eur J Human Genet 17:629-635
13. Sirachainan N, Wongruangsri S, Kajanachumpol S (2008) Folate pathway genetic polymorphisms and susceptibility of central nervous system tumors in Thai children. Cancer Detect Prev 32:72-78
14. Lima ELS, Silva VC, Silva HDA et al (2010) MTR polymorphic variant A2756G and retinoblastoma risk in Brazilian children. Pediatr Blood Cancer 54:904-908
15. Ulrich CM, Curtin K, Potter JD et al (2005) Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer. Cancer Epidem Biomar 14:2509-2516 (Pubitemid 41752708)
16. Chango A, Emery-Fillon N, Courcy GP et al (2000) A polymorphism (80G->A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia. Mol Genet Metab 70:310-315
17. Van Der Put NMJ, Van Der Molen EF, Kluijtmans LA et al (1997) Sequence analysis of the coding region of human methionine synthase: relevance to hyperhomocysteinemia in neuraltube defects and vascular disease. QJM 90:511-517 (Pubitemid 27379815)
18. Frosst P, Blom HJ, Milos R et al (1995) A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 10:111-113
19. Van Der Put NMJ, Gabreëls F, Stevens EMB et al (1998) A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet 62:1044-1051
20. Kawakami K, Omura K, Kanehira E et al (1999) Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers. Anticancer Res 19:3249-3252 (Pubitemid 30042617)
21. Blount BC, Mack MM, Wehr CM et al (1997) Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage. Proc Natl Acad Sci USA 94:3290-3295
22. Rhys CM, Bohr VA (1996) Mammalian DNA repair responses and genomic instability. EXE 77:289-305
23. Usmani BA (1993) Genomic instability and metastatic progression. Pathobiol 61:109-116
24. Sambrook J, Russel DW (2001) Rapid isolation of yeast DNA. In: Hoffman CS (ed) Molecular cloning, a laboratory manual. Cold Spring Harbor Laboratory, New York, pp 631-632
25. Nascimento EM, Spinelli MO, Rodrigues CJ et al (2003) Protocolo da extração de DNA de material parafinado para análise de microssatélites em leiomioma. J Bras Patol Med Lab 39(3):253-255
26. Biselli JM, Goloni-Bertollo EM, Haddad R et al (2008) The MTR A2756G polymorphism is associated with an increase of plasma homocysteine concentration in Brazilian individuals with down syndrome. Braz J Med Biol Res 41(1):34-40 (Pubitemid 351425867)
27. Harmon DL, Shields DC, Woodside JV et al (1999) Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations. Genet Epidemiol 17:298-309 (Pubitemid 29522203)
28. Hishida A, Matsuo K, Hamajima N et al (2003) Associations between polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and susceptibility to malignant lymphoma. Haematol 88:159-166 (Pubitemid 37101493)
29. Davis SS, Rogers MA, Pendergrass TW (1987) The incidence and epidemiologic characteristics of neuroblastoma in the US. Am J Epidemiol 126:1063-1074
30. Grovas A, Fremgen A, Rauck A et al (1997) The National Cancer Data Base report on patterns of childhood cancers in the US. Cancer 80:2321-2332 (Pubitemid 28007404)
31. Matherly LH, Hou Z, Deng Y (2007) Human reduced folate carrier: translation of basic biology to cancer etiology and therapy. Cancer Metast Rev 26:111-128 (Pubitemid 46452186)
32. Whetstine JR, Gifford AJ, Witt T et al (2001) Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the His [27] and Arg [27] carriers. Clin Cancer Res 7:3416-3422 (Pubitemid 33069975)
33. De Marco P, Calevo MG, Moroni A et al (2001) Polymorphisms in genes involved in folate metabolism as risk factors for NTDs. Eur J Pediatr Surg 11:S14-S17
34. Shaw GM, Lammer EJ, Zhu H et al (2002) Maternal periconceptional vitamin use, genetic variation of infant reduced folate carrier (A80G), and risk of spina bifida. Am J Med Genet 108:1-6 (Pubitemid 34101374)
35. Morin I, Devlin AM, Leclerc D et al (2003) Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk. Mol Genet Metab 79:197-200 (Pubitemid 36809047)
36. Pei L, Zhu H, Ren A et al (2005) Reduced folate carrier gene is a risk factor for neural tube defects in a Chinese population, birth defects. Res A Clin Mol Teratol 73:430-433
37. Li J, Shi Y, Sun J et al (2011) Xenopus reduced folate carrier regulates neural crest development epigenetically. PLoS ONE 6:e27198
38. Wang L, Chen W, Wang J et al (2006) Reduced folate carrier gene G80A polymorphism is associated with an increased risk of gastroesophageal cancers in a chinese population. Eur J Cancer 42:3206-3211 (Pubitemid 44854505)
39. Skibola CF, Forrest MS, Coppede F et al (2004) Polymorphisms and haplotypes in folate-metabolizing genes and risk of non- Hodgkin lymphoma. Blood 104:2155-2162 (Pubitemid 39297871)
40. Laverdiere C, Chiasson S, Costea I et al (2002) Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia. Blood 100:3832-3834 (Pubitemid 35303961)
41. Antony AC (2007) In utero physiology: role of folic acid in nutrient delivery and fetal development. Am J Clin Nutr 85:598S-603S
42. Ashworth CJ, Antipatis C (2001) Micronutrient programming of development throughout gestation. Reprod 122:527-535 (Pubitemid 32975959) Nível Superior