N-linked glycosylation of the bone morphogenetic protein receptor type 2 (BMPR2) enhances ligand binding

Cellular and Molecular Life Sciences

Volumn 71, Issue 16, 2014, Pages 3165-3172

  Lowery, Jonathan W ^a   Amich, Jose M ^a   Andonian, Alex ^a   Rosen, Vicki ^a  

^a HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

Activin; ACVR2A; ACVR2B; BMPR2; Bone morphogenetic protein; Glycosylation; Heritable pulmonary arterial hypertension; Pulmonary hypertension

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN RECEPTOR; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; PROTEIN ACVR2A; PROTEIN ACVR2B; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE MUTATION; GENETIC DISORDER; HUMAN; HUMAN CELL; LIGAND BINDING; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; PROTEIN DEFECT; PROTEIN DOMAIN; PROTEIN GLYCOSYLATION; PROTEIN PROCESSING; PULMONARY HYPERTENSION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

ACTIVIN RECEPTORS, TYPE II; AMINO ACID SEQUENCE; BINDING SITES; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; CELL LINE; GLYCOSYLATION; HUMANS; HYPERTENSION, PULMONARY; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84905096623     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-013-1541-8     Document Type: Article

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