Lidocaine and ropivacaine, but not bupivacaine, demethylate deoxyribonucleic acid in breast cancer cells in vitro

British Journal of Anaesthesia

Volumn 113, Issue SUPPL. 1, 2014, Pages

  Lirk, P ^a   Hollmann, M W ^a   Fleischer, M ^b   Weber, N C ^a   Fiegl, H ^b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

cancer; demethylation; epigenetics; local anaesthetic bupivacaine; local anaesthetic lidocaine; local anaesthetic ropivacaine

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ANESTHETIC AGENT; BUPIVACAINE; DNA; ESTROGEN RECEPTOR; LIDOCAINE; ROPIVACAINE;

ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CANCER CHEMOTHERAPY; CELL COUNT; DNA METHYLATION; DRUG EFFECT; DRUG POTENTIATION; EPIGENETICS; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; HUMAN; HUMAN CELL; IN VITRO STUDY; MCF 7 CELL LINE; PRIORITY JOURNAL;

CANCER; DEMETHYLATION; EPIGENETICS; LOCAL ANAESTHETIC, BUPIVACAINE; LOCAL ANAESTHETIC, LIDOCAINE; LOCAL ANAESTHETIC, ROPIVACAINE;

AMIDES; ANESTHETICS, LOCAL; ANTIMETABOLITES, ANTINEOPLASTIC; AZACITIDINE; BREAST NEOPLASMS; BUPIVACAINE; CELL SURVIVAL; DNA METHYLATION; DNA, NEOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; EPIGENESIS, GENETIC; FEMALE; HUMANS; LIDOCAINE; MCF-7 CELLS; TUMOR CELLS, CULTURED;

EID: 84905040934     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aeu201     Document Type: Article

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