The mechanisms of up-regulation of dendritic cell activity by oxidative stress

Journal of Leukocyte Biology

Volumn 96, Issue 2, 2014, Pages 283-293

  Batal, Ibrahim ^a   Azzi, Jamil ^a   Mounayar, Marwan ^a   Abdoli, Rozita ^a   Moore, Robert ^a   Lee, Jack Y ^a   Rosetti, Florencia ^a   Wang, Chang ^a   Fiorina, Paolo ^a   Sackstein, Robert ^a   Ichimura, Takaharu ^a   Abdi, Reza ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Migration; T cell activation

Indexed keywords

CYTOKINE; GAMMA INTERFERON; HYPOXANTHINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; OVALBUMIN; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PROTEIN KINASE B; XANTHINE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DENDRITIC CELL; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR UPREGULATION; REPERFUSION INJURY; T LYMPHOCYTE ACTIVATION;

H2O2; MIGRATION; T CELL ACTIVATION;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; CYTOKINES; DENDRITIC CELLS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; NF-KAPPA B; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; T-LYMPHOCYTES, REGULATORY; UP-REGULATION;

EID: 84904998277     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.3A0113-033RR     Document Type: Article

References (52)

1. Black, S. C., Rodger, I. W. (1996) Methods for studying experimental myocardial ischemic and reperfusion injury. J. Pharmacol. Toxicol. Methods 35, 179-190.
2. Eltzschig, H. K., Eckle, T. (2011) Ischemia and reperfusion-from mechanism to translation. Nat. Med. 17, 1391-1401.
3. Nelson, P. J. (2007) Renal ischemia-reperfusion injury: renal dendritic cells loudly sound the alarm. Kidney Int. 71, 604-605.
4. Bonasio, R., von Andrian, U. H. (2006) Generation, migration and function of circulating dendritic cells. Curr. Opin. Immunol. 18, 503-511.
5. Jurewicz, M., Takakura, A., Augello, A., Naini, S. M., Ichimura, T., Zandi-Nejad, K., Abdi, R. (2010) Ischemic injury enhances dendritic cell immunogenicity via TLR4 and NF-κ B activation. J. Immunol. 184, 2939-2948.
6. Land, W. G. (2012) Emerging role of innate immunity in organ transplantation part II: potential of damage-associated molecular patterns to generate immunostimulatory dendritic cells. Transplant. Rev. (Orlando) 26, 73-87.
7. Bosco, M. C., Puppo, M., Blengio, F., Fraone, T., Cappello, P., Giovarelli, M., Varesio, L. (2008) Monocytes and dendritic cells in a hypoxic environment: spotlights on chemotaxis and migration. Immunobiology 213, 733-749.
8. Kostulas, N., Li, H. L., Xiao, B. G., Huang, Y. M., Kostulas, V., Link, H. (2002) Dendritic cells are present in ischemic brain after permanent middle cerebral artery occlusion in the rat. Stroke 33, 1129-1134.
9. Rutault, K., Alderman, C., Chain, B. M., Katz, D. R. (1999) Reactive oxygen species activate human peripheral blood dendritic cells. Free Radic. Biol. Med. 26, 232-238.
10. Verhasselt, V., Goldman, M., Willems, F. (1998) Oxidative stress up-regulates IL-8 and TNF-α synthesis by human dendritic cells. Eur. J. Immunol. 28, 3886-3890.
11. Land, W. G. (2005) The role of postischemic reperfusion injury and other nonantigen-dependent inflammatory pathways in transplantation. Transplantation 79, 505-514.
12. Jurewicz, M., Ueno, T., Azzi, J., Tanaka, K., Murayama, T., Yang, S., Sayegh, M. H., Niimi, M., Abdi, R. (2011) Donor antioxidant strategy prolongs cardiac allograft survival by attenuating tissue dendritic cell immunogenicity(dagger). Am. J. Transplant. 11, 348-355.
13. Kim, B. S., Lim, S. W., Li, C., Kim, J. S., Sun, B. K., Ahn, K. O., Han, S. W., Kim, J., Yang, C. W. (2005) Ischemia-reperfusion injury activates innate immunity in rat kidneys. Transplantation 79, 1370-1377.
14. Loverre, A., Capobianco, C., Stallone, G., Infante, B., Schena, A., Ditonno, P., Palazzo, S., Battaglia, M., Crovace, A., Castellano, G., Ranieri, E., Schena, F. P., Gesualdo, L., Grandaliano, G. (2007) Ischemia-reperfusion injury-induced abnormal dendritic cell traffic in the transplanted kidney with delayed graft function. Kidney Int. 72, 994-1003.
15. Mashreghi, M. F., Klemz, R., Knosalla, I. S., Gerstmayer, B., Janssen, U., Buelow, R., Jozkowicz, A., Dulak, J., Volk, H. D., Kotsch, K. (2008) Inhibition of dendritic cell maturation and function is independent of heme oxygenase 1 but requires the activation of STAT3. J. Immunol. 180, 7919-7930.
16. Camps, M., Ruckle, T., Ji, H., Ardissone, V., Rintelen, F., Shaw, J., Ferrandi, C., Chabert, C., Gillieron, C., Francon, B., Martin, T., Gretener, D., Perrin, D., Leroy, D., Vitte, P. A., Hirsch, E., Wymann, M. P., Cirillo, R., Schwarz, M. K., Rommel, C. (2005) Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat. Med. 11, 936-943.
17. Ghigo, A., Hirsch, E. (2008) Isoform selective phosphoinositide 3-kinase γ and δ inhibitors and their therapeutic potential. Recent Pat. Inflamm. Allergy Drug Discov. 2, 1-10.
18. Agrawal, A., Agrawal, S., Cao, J. N., Su, H., Osann, K., Gupta, S. (2007) Altered innate immune functioning of dendritic cells in elderly humans: a role of phosphoinositide 3-kinase-signaling pathway. J. Immunol. 178, 6912-6922.
19. Del Prete, A., Vermi, W., Dander, E., Otero, K., Barberis, L., Luini, W., Bernasconi, S., Sironi, M., Santoro, A., Garlanda, C., Facchetti, F., Wymann, M. P., Vecchi, A., Hirsch, E., Mantovani, A., Sozzani, S. (2004) Defective dendritic cell migration and activation of adaptive immunity in PI3Kγ-deficient mice. EMBO J. 23, 3505-3515.
20. Barbier, M., Attoub, S., Calvez, R., Laffargue, M., Jarry, A., Mareel, M., Altruda, F., Gespach, C., Wu, D., Lu, B., Hirsch, E., Wymann, M. P. (2001) Tumour biology. Weakening link to colorectal cancer? Nature 413, 796.
21. Tang, D., Shi, Y., Kang, R., Li, T., Xiao, W., Wang, H., Xiao, X. (2007) Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1. J. Leukoc. Biol. 81, 741-747.
22. Lassen, S., Lech, M., Rommele, C., Mittruecker, H. W., Mak, T. W., Anders, H. J. (2010) Ischemia reperfusion induces IFN regulatory factor 4 in renal dendritic cells, which suppresses postischemic inflammation and prevents acute renal failure. J. Immunol. 185, 1976-1983.
23. Sadhu, C., Masinovsky, B., Dick, K., Sowell, C. G., Staunton, D. E. (2003) Essential role of phosphoinositide 3-kinase δ in neutrophil directional movement. J. Immunol. 170, 2647-2654.
24. Berkman, W. A., Chowdhury, L., Brown, N. L., Padleckas, R. (1983) Value of electron microscopy in cytologic diagnosis of fine-needle biopsy. Am. J. Roentgenol. 140, 1253-1258.
25. Lee, J. Y., Buzney, C. D., Poznansky, M. C., Sackstein, R. (2009) Dynamic alterations in chemokine gradients induce transendothelial shuttling of human T cells under physiologic shear conditions. J. Leukoc. Biol. 86, 1285-1294.
26. Fiorina, P., Jurewicz, M., Vergani, A., Augello, A., Paez, J., Ricchiuti, V., Tchipachvili, V., Sayegh, M. H., Abdi, R. (2008) Phenotypic and functional differences between wild-type and CCR2-/-dendritic cells: implications for islet transplantation. Transplantation 85, 1030-1038.
27. Wobben, R., Husecken, Y., Lodewick, C., Gibbert, K., Fandrey, J., Winning, S. (2013) Role of hypoxia inducible factor-1β for interferon synthesis in mouse dendritic cells. Biol. Chem. 394, 495-505.
28. Inaba, K., Swiggard, W. J., Steinman, R. M., Romani, N., Schuler, G., Brinster, C. (2009) Isolation of dendritic cells. Curr. Protoc. Immunol. Chapter 3, Unit 3. 7.
29. Xing, F., Wang, J., Hu, M., Yu, Y., Chen, G., Liu, J. (2011) Comparison of immature and mature bone marrow-derived dendritic cells by atomic force microscopy. Nanoscale Res. Lett. 6, 455.
30. Zeng, X., Wang, T., Zhu, C., Xing, X., Ye, Y., Lai, X., Song, B., Zeng, Y. (2012) Topographical and biological evidence revealed FTY720-mediated anergy-polarization of mouse bone marrow-derived dendritic cells in vitro. PLoS One 7, e34830.
31. Randolph, G. J., Ochando, J., Partida-Sanchez, S. (2008) Migration of dendritic cell subsets and their precursors. Annu. Rev. Immunol. 26, 293-316.
32. Baud, L., Ardaillou, R. (1993) Involvement of reactive oxygen species in kidney damage. Br. Med. Bull. 49, 621-629.
33. McCord, J. M. (1985) Oxygen-derived free radicals in postischemic tissue injury. N. Engl. J. Med. 312, 159-163.
34. Bolli, R., Patel, B. S., Jeroudi, M. O., Lai, E. K., McCay, P. B. (1988) Demonstration of free radical generation in "stunned" myocardium of intact dogs with the use of the spin trap α-phenyl N-tert-butyl nitrone. J. Clin. Invest. 82, 476-485.
35. Bolli, R., Jeroudi, M. O., Patel, B. S., DuBose, C. M., Lai, E. K., Roberts, R., McCay, P. B. (1989) Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog. Proc. Natl. Acad. Sci. USA 86, 4695-4699.
36. Grech, E. D., Dodd, N. J., Jackson, M. J., Morrison, W. L., Faragher, E. B., Ramsdale, D. R. (1996) Evidence for free radical generation after primary percutaneous transluminal coronary angioplasty recanalization in acute myocardial infarction. Am. J. Cardiol. 77, 122-127.
37. Li, L., Okusa, M. D. (2010) Macrophages, dendritic cells, and kidney ischemia-reperfusion injury. Semin. Nephrol. 30, 268-277.
38. Banchereau, J., Steinman, R. M. (1998) Dendritic cells and the control of immunity. Nature 392, 245-252.
39. Soos, T. J., Sims, T. N., Barisoni, L., Lin, K., Littman, D. R., Dustin, M. L., Nelson, P. J. (2006) CX3CR1β interstitial dendritic cells form a contiguous network throughout the entire kidney. Kidney Int. 70, 591-596.
40. Steptoe, R. J., Patel, R. K., Subbotin, V. M., Thomson, A. W. (2000) Comparative analysis of dendritic cell density and total number in commonly transplanted organs: morphometric estimation in normal mice. Transpl. Immunol. 8, 49-56.
41. Nace, G., Evankovich, J., Eid, R., Tsung, A. (2012) Dendritic cells and damage-associated molecular patterns: endogenous danger signals linking innate and adaptive immunity. J. Innate Immun. 4, 6-15.
42. Tsung, A., Sahai, R., Tanaka, H., Nakao, A., Fink, M. P., Lotze, M. T., Yang, H., Li, J., Tracey, K. J., Geller, D. A., Billiar, T. R. (2005) The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemiareperfusion. J. Exp. Med. 201, 1135-1143.
43. Zhai, Y., Shen, X. D., O'Connell, R., Gao, F., Lassman, C., Busuttil, R. W., Cheng, G., Kupiec-Weglinski, J. W. (2004) Cutting edge: TLR4 activation mediates liver ischemia/reperfusion inflammatory response via IFN regulatory factor 3-dependent MyD88-independent pathway. J. Immunol. 173, 7115-7119.
44. Sharma, H. S., Das, D. K. (1997) Role of cytokines in myocardial ischemia and reperfusion. Mediators Inflamm. 6, 175-183.
45. Fonseca, J. E., Santos, M. J., Canhao, H., Choy, E. (2009) Interleukin-6 as a key player in systemic inflammation and joint destruction. Autoimmun. Rev. 8, 538-542.
46. Navarro-Millan, I., Singh, J. A., Curtis, J. R. (2012) Systematic review of tocilizumab for rheumatoid arthritis: a new biologic agent targeting the interleukin-6 receptor. Clin. Ther. 34, 788-802.
47. Wan, S., Xia, C., Morel, L. (2007) IL-6 produced by dendritic cells from lupus-prone mice inhibits CD4+CD25+ T cell regulatory functions. J. Immunol. 178, 271-279.
48. Pasare, C., Medzhitov, R. (2003) Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 299, 1033-1036.
49. Liang, Y., Christopher, K., Finn, P. W., Colson, Y. L., Perkins, D. L. (2007) Graft produced interleukin-6 functions as a danger signal and promotes rejection after transplantation. Transplantation 84, 771-777.
50. Gajewski, T. F., Schell, S. R., Nau, G., Fitch, F. W. (1989) Regulation of T-cell activation: differences among T-cell subsets. Immunol. Rev. 111, 79-110.
51. Willimann, K., Legler, D. F., Loetscher, M., Roos, R. S., Delgado, M. B., Clark-Lewis, I., Baggiolini, M., Moser, B. (1998) The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7. Eur. J. Immunol. 28, 2025-2034.
52. Ruckle, T., Schwarz, M. K., Rommel, C. (2006) PI3Kγ inhibition: towards an "aspirin of the 21st century"? Nat. Rev. Drug Discov. 5, 903-918.