Comparative analysis of dendritic cell density and total number in commonly transplanted organs: Morphometric estimation in normal mice

Transplant Immunology

Volumn 8, Issue 1, 2000, Pages 49-56

  Steptoe, Raymond J ^a   Patel, Rajan K ^b   Subbotin, Vladimir M ^c   Thomson, Angus W ^d  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Allograft; Cell density; Dendritic cells; Passenger leukocytes

Indexed keywords

CD45 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ALLOIMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; COMPARATIVE STUDY; DENDRITIC CELL; DONOR; FEMALE; FROZEN SECTION; HEART; IMMUNOCYTOCHEMISTRY; KIDNEY; LEUKOCYTE; LIVER; MOUSE; NONHUMAN; ORGAN TRANSPLANTATION; PANCREAS; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD45; CELL COUNT; DENDRITIC CELLS; FEMALE; HEART TRANSPLANTATION; HISTOCOMPATIBILITY ANTIGENS CLASS II; KIDNEY TRANSPLANTATION; LEUKOCYTES; LIVER TRANSPLANTATION; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; PANCREAS TRANSPLANTATION;

EID: 0034025567     PISSN: 09663274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0966-3274(00)00010-1     Document Type: Article

References (30)

1. Banchereau J, Steinman RM. Dendritic cells and the control of immunity. Nature 1998;392:245-252.
2. Bell D, Young JW, Banchereau J. Dendritic cells. Adv Immunol 1999;72:255-324.
3. Crowley M, Inaha K, Steinman RM. Dendritic cells are the principal cells in mouse spleen bearing immunogenic fragments of foreign proteins. J Exp Med 1990; 172:383-386.
4. Knight SC, Merlin J, Clark J. Induction of immune responses in vivo with small numbers of veiled (dendritic cells). Proc Natl Acad Sei USA 1983;80:6032-6035
5. Inaba K, Metlay JP, Crowley MT, Steinman RM. Dendritic cells pulsed with protein antigens in vitro can prime antigenspecific, MHC-restricted T cells in situ. J Exp Med 1990:172:631-640.
6. Lechler RI, Batchelor JR. Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells. J Exp Med 1982;155:31-41.
7. Faustman DL, Steinman RM, Gebel HM, Hauptfeld V, Davie JM, Lacy PE. Prevention of rejection of murine islet allograft survival by pretreatment with anti-dendritic cell antibody. Proc Natl Acad Sei USA 1984;81:3864-3868.
8. McKenzie JE, Beard MEJ, Hart DNJ. The effect of donor pretreatment on interstitial dendritic cell content and rat cardiac allograft survival. Transplantation 1984;38:371-376.
9. Rastellini C, Eu E, Ricordi C, Starzl TE, Rao AS, Thomson AW. Granulocyte-macrophage colony stimulating factorstimulated hepatic dendritic cell progenitors prolong pancreatic islet allograft survival. Transplantation 1995;60:1366-1370.
10. -) prolong cardiac allograft survival in non-immunosuppressed recipients. Transplantation 1996;62:659-665.
11. Hayamizu K, Huie P, Sibley RK, Strober S. Monocyte-derived dendritic cell precursors facilitate tolerance to heart allografts after total lymphoid irradiation. Transplantation 1998;66: 1285-1291.
12. Steptoe RJ, Fu F, Ei W et al. Augmentation of dendritic cells in murine organ donors by flt3 ligand alters the balance between transplant tolerance and immunity. J Immunol 1997; 159: 5483-5491.
13. Gundersen HJG, Bagger P, Bendtsen TF et al. The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. APMIS 1988;96:857-881.
14. Sterio DC. The unbiased estimation of number and size of arbitrary particles using the disector. J Microsc 1984;134: 127-136.
15. Thomson AW, Lu L. Murase N, Demetris AJ, Rao AS, Starzl TE. Microchimerism, dendritic cell progenitors and transplantation tolerance. Stem Cells 1995:13:622-639.
16. Thomson AW. Lu L. Are dendritic cells the key to liver transplant tolerance? Immunol Today 1999:20:27-32.
17. Austyn JM. Hankins DF. Larsen CP, Morris PJ. Rao AS. Roake JA. Isolation and characterization of dendritic cells from mouse heart and kidney. J Immunol 1994:152:2401-241(1.
18. Woo J. Lu L, Rao AS et al. Isolation, phenotype. and allostimulatory activity of mouse liver dendritic cells. Transplantation 1994:58:484-491.
19. Hart DNJ, Fahre JW. Demonstration and characterisation of la-positive dendritic cells in the interstitial connective tissues of rat heart and other tissues, hut not brain. J Exp Med 1981; 153:347-361.
20. Hart DNJ, McKenzie JL. Interstitial dendritic cells. Int Rev Immunol 1990:6:127-138.
21. Shaw SG. Maung AA. Steptoe RJ, Thomson AW, Vujanovic NL. Expansion of functional NK cells in multiple tissue compartments of mice treated with Flt3-ligand: implications for anti-cancer and anti-viral therapy. J Immunol 1998:161: 2817-2824.
22. Qian S. Demetris AJ. Murase N. Rao AS, Fung JJ. Starzl TE. Murine liver allograft transplantation: tolerance and donor cell chimerism. Hepatology 1994:19:916-924.
23. Zhang Z, Zhu L, Quan D et al. Pattern of liver, kidney, heart and intestine allograft survival in different mouse strain combinations. Transplantation 1996:62:1267- 1272.
24. Burdick JF. Clow LW. Rejection of murine cardiac allografts. I. The relative roles of major and minor antigens. Transplantation 1986:42:67-72.
25. Mottram PL. Murray-Segal LJ. Li YQ. Man WR. Sandrin M. McKenzie IFC. Effect of IL-4 deletion on cardiac allograft sui-vival in BALB/c to 129Sv x C57BL/'1 strain combination. Immunol Cell Biol 1998:76:563- 565.
26. Purcell LJ. Mottram PL. Mandel TE. Immunosiippressive antibody treatment prolongs graft survival in two murine models of segmental pancreas transplantation. Immunol Cell Biol 1993:71:349-352.
27. Bergstresser PR. Fletcher CR, Streilein JW. Surface densities of Langerhans cells in relation to rodent epidermal sites with special immunologie properties. J Invest Dermatol 1980:74: 77-80.
28. Demetris AJ. Qian S. Sun H et al. Early events in liver allograft rejection. Delineation of sites of simultaneous intragraft and recipient lymphoid tissue sensiti/ation. Am J Pathol 1991: 138:609-618.
29. Forties RDC. Parfrey NA. Gomersall M. Harden AG. Guttmann RD. Dendritic eell-lymphoid cell aggregation and major histocompatihility antigen expression during rat cardiac allograft rejection. J Exp Med 1986:164:1239-1258.
30. Gould IX Auchincloss II. Direct and indirect recognition: the role of MHC antigens in graft rejection. Immunol Today 1999:20:77-82.