Sigma-1 receptor antagonism restores injury-induced decrease of voltage-gated Ca2+ current in sensory neurons

Journal of Pharmacology and Experimental Therapeutics

Volumn 350, Issue 2, 2014, Pages 290-300

  Pan, Bin ^a   Guo, Yuan ^a   Kwok, Wai Meng ^a   Hogan, Quinn ^a,b   Wu, Hsiang En ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (3,4 DICHLOROPHENYL)ETHYL] 4 METHYLPIPERAZINE DIHYDROCHLORIDE; 1,3 BIS(2 METHYLPHENYL)GUANIDINE; BD 1063; ENZYME INHIBITOR; N [2 (3,4 DICHLOROPHENYL)ETHYL] 2 DIMETHYLAMINO N METHYLETHYLAMINE; PENTAZOCINE; SIGMA 1 OPIATE RECEPTOR; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; ELECTROPHYSIOLOGY; ENZYME INACTIVATION; ENZYME KINETICS; GLIA CELL; MALE; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RAT; SENSORY NERVE CELL; SPINAL GANGLION; SPINAL NERVE LIGATION INJURY; SYNAPTIC TRANSMISSION; WHOLE CELL PATCH CLAMP;

ANIMALS; CALCIUM CHANNELS; ETHYLENEDIAMINES; GANGLIA, SPINAL; MALE; PERIPHERAL NERVE INJURIES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SIGMA; SENSORY RECEPTOR CELLS;

EID: 84904994795     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.214320     Document Type: Article

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