Antagonists show GTP-sensitive high-affinity binding to the sigma-1 receptor

British Journal of Pharmacology

Volumn 164, Issue 2 B, 2011, Pages 772-780

  Brimson, J M ^a,c   Brown, C A ^b   Safrany, S T ^a,b  

^a University of Bath   (United Kingdom)

^b UNIVERSITY OF WOLVERHAMPTON   (United Kingdom)

^c CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

agonist; antagonist; calcium; cholera toxin; G protein; IPAG; MTS; rimcazole; Sigma 1 receptor

Indexed keywords

CHOLERA TOXIN; FURA 2; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATE; OPIATE AGONIST; OPIATE ANTAGONIST; PENTAZOCINE; RADIOLIGAND; SIGMA 1 OPIATE RECEPTOR; SIGMA 1 OPIATE RECEPTOR ANTAGONIST; SURAMIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CALCIUM SIGNALING; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVITY; METABOLISM; PRIORITY JOURNAL; PROTEIN INTERACTION; RECEPTOR BINDING;

BINDING SITES; BINDING, COMPETITIVE; CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; CHOLERA TOXIN; FURA-2; GTP-BINDING PROTEINS; GUANOSINE TRIPHOSPHATE; HUMANS; PENTAZOCINE; PROTEIN BINDING; RECEPTORS, SIGMA; SURAMIN;

EID: 80052236374     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01417.x     Document Type: Article

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