σ-1 receptor agonist SKF10047 inhibits glutamate release in rat cerebral cortex nerve endings

Journal of Pharmacology and Experimental Therapeutics

Volumn 341, Issue 2, 2012, Pages 532-542

  Lu, Cheng Wei ^a   Lin, Tzu Yu ^a,b   Wang, Chia Chuan ^c   Wang, Su Jane ^c,d  

^a FAR EASTERN MEMORIAL HOSPITAL   (Taiwan)

^b YUAN ZE UNIVERSITY   (Taiwan)

^c FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^d FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOPYRIDINE; BAFILOMYCIN A1; CALCIUM CHANNEL N TYPE; CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; CALCIUM ION; GLUTAMIC ACID; N [2 (3,4 DICHLOROPHENYL)ETHYL] 2 DIMETHYLAMINO N METHYLETHYLAMINE; N ALLYLNORMETAZOCINE; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; RYANODINE RECEPTOR; SODIUM CALCIUM EXCHANGE PROTEIN; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL ISOLATION; CONTROLLED STUDY; DEPOLARIZATION; DRUG EFFECT; DRUG MECHANISM; ENZYME PHOSPHORYLATION; MALE; MOLECULAR DYNAMICS; NERVE ENDING; NONHUMAN; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; RAT; SYNAPTIC POTENTIAL; WESTERN BLOTTING;

4-AMINOPYRIDINE; AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ASPARTIC ACID; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CALCIUM CHANNELS, N-TYPE; CEREBRAL CORTEX; CYTOSOL; GLUTAMIC ACID; MACROLIDES; MALE; MEMBRANE POTENTIALS; MITOCHONDRIA; NERVE ENDINGS; PHENAZOCINE; PHOSPHORYLATION; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SIGMA; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SODIUM-CALCIUM EXCHANGER; VESICULAR TRANSPORT PROTEINS;

EID: 84859949968     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.191189     Document Type: Article

References (43)

1. Akerman KE, Scott IG, Heikkilä JE, and Heinonen E (1987) Ionic dependence of membrane potential and glutamate receptor-linked responses in synaptoneurosomes as measured with a cyanine dye, DiSC2(5). J Neurochem 48:552-559. (Pubitemid 17005167)
2. 1 receptor in the adult rat central nervous system. Neuroscience 97:155-170.
3. Barrie AP, Nicholls DG, Sanchez-Prieto J, and Sihra TS (1991) An ion channel locus for the protein kinase C potentiation of transmitter glutamate release from guinea pig cerebrocortical synaptosomes. J Neurochem 57:1398-1404. (Pubitemid 21922768)
4. Berridge MJ (1998) Neuronal calcium signaling. Neuron 21:13-26.
5. Blaustein MP and Lederer WJ (1999) Sodium/calcium exchange: its physiological implications. Physiol Rev 79:763-854. (Pubitemid 29330173)
6. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
7. Brown DA and Sihra TS (2008) Presynaptic signaling by heterotrimeric G-proteins. Handb Exp Pharmacol 184:207-260.
8. 1 receptor ligands. Curr Neuropharmacol 6:344-366.
9. Coffey ET, Sihra TS, and Nicholls DG (1993) Protein kinase C and the regulation of glutamate exocytosis from cerebrocortical synaptosomes. J Biol Chem 268:21060-21065. (Pubitemid 23292290)
10. 2+ channel which is coupled to glutamate exocytosis. FEBS Lett 353:264-268.
11. Craig TJ, Evans GJ, and Morgan A (2003) Physiological regulation of Munc18/nSec1 phosphorylation on serine-313. J Neurochem 86:1450-1457. (Pubitemid 37174261)
12. DeCoster MA, Klette KL, Knight ES, and Tortella FC (1995) Sigma receptor-mediated neuroprotection against glutamate toxicity in primary rat neuronal cultures. Brain Res 671:45-53.
13. Greenamyre JT and Porter RH (1994) Anatomy and physiology of glutamate in the CNS. Neurology 44:S7-S13.
14. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
15. Herrero I, Miras-Portugal MT, and Sánchez-Prieto J (1992) Positive feedback of glutamate exocytosis by metabotropic presynaptic receptor stimulation. Nature 360:163-166.
16. Institute of Laboratory Animal Resources (1996) Guide for the Care and Use of Laboratory Animals 7th ed. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, Washington, DC.
17. 2+ channels, cytoplasmic messengers and proteins of the synaptic vesicle release complex. Trends Pharmacol Sci 22:519-525.
18. Marrazzo A, Caraci F, Salinaro ET, Su TP, Copani A, and Ronsisvalle G (2005) Neuroprotective effects of σ-1 receptor agonists against α-amyloid-induced toxicity. Neuroreport 16:1223-1226. (Pubitemid 41058473)
19. Maurice T and Su TP (2009) The pharmacology of σ-1 receptors. Pharmacol Ther 124:195-206.
20. 1) receptor agonists and neurosteroids attenuate B25-35-amyloid peptide-induced amnesia in mice through a common mechanism. Neuroscience 83:413-428.
21. Meldrum BS (2000) Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 130:1007S-1015S.
22. Millán C and Sánchez-Prieto J (2002) Differential coupling of N- and P/Q-type calcium channels to glutamate exocytosis in the rat cerebral cortex. Neurosci Lett 330:29-32.
23. Nicholls DG (1993) The glutamatergic nerve terminal. Eur J Biochem 212:613-631.
24. Nicholls DG (1998) Presynaptic modulation of glutamate release. Prog Brain Res 116:15-22.
25. Nicholls DG, Sihra TS, and Sanchez-Prieto J (1987) Calcium-dependent and -independent release of glutamate from synaptosomes monitored by continuous fluorometry. J Neurochem 49:50-57.
26. Obrenovitch TP and Urenjak J (1997) Altered glutamatergic transmission in neurological disorders: from high extracellular glutamate to excessive synaptic efficacy. Prog Neurobiol 51:39-87. (Pubitemid 27080814)
27. Schinder AF, Olson EC, Spitzer NC, and Montal M (1996) Mitochondrial dysfunction is a primary event in glutamate neurotoxicity. J Neurosci 16:6125-6133. (Pubitemid 26313988)
28. Senda T, Mita S, Kaneda K, Kikuchi M, and Akaike A (1998) Effect of SA4503, a novel sigma1 receptor agonist, against glutamate neurotoxicity in cultured rat retinal neurons. Eur J Pharmacol 342:105-111. (Pubitemid 28131351)
29. Shearman MS, Shinomura T, Oda T, and Nishizuka Y (1991) Synaptosomal protein kinase C subspecies: A. Dynamic change in the hippocampus and cerebellar cortex concomitant with synaptogenesis. J Neurochem 56:1255-1262. (Pubitemid 21902044)
30. 2+ entry preferentially effects protein dephosphorylation, phosphorylation, and glutamate release. J Biol Chem 267:1983-1989.
31. Soriani O, Foll FL, Roman F, Monnet FP, Vaudry H, and Cazin L (1999) A-current down-modulated by σ receptor in frog pituitary melanotrope cells through a G protein-dependent pathway. J Pharmacol Exp Ther 289:321-328. (Pubitemid 29156045)
32. Takahashi H, Kirsch JR, Hashimoto K, London ED, Koehler RC, and Traystman RJ (1995) PPBP [4-phenyl-1-(4-phenylbutyl) piperidine], a potent σ-receptor ligand, decreases brain injury after transient focal ischemia in cats. Stroke 26:1676-1682.
33. Tchedre KT, Huang RQ, Dibas A, Krishnamoorthy RR, Dillon GH, and Yorio T (2008) Sigma-1 receptor regulation of voltage-gated calcium channels involves a direct interaction. Invest Ophthalmol Vis Sci 49:4993-5002.
34. Tchedre KT and Yorio T (2008) σ-1receptors protect RGC-5 cells from apoptosis by regulating intracellular calcium, Bax levels, and caspase-3 activation. Invest Ophthalmol Vis Sci 49:2577-2588.
35. Vaughan PF, Walker JH, and Peers C (1998) The regulation of neurotransmitter secretion by protein kinase C. Mol Neurobiol 18:125-155. (Pubitemid 29083006)
36. 2+ entry in rat cerebrocortical nerve terminals (synaptosomes). J Pharmacol Exp Ther 309:951-958.
37. + channel modulation in rodent neurohypophysial nerve terminals by σ receptors and not by dopamine receptors. J Physiol 517:391-406.
38. Wu LG and Saggau P (1997) Presynaptic inhibition of elicited neurotransmitter release. Trends Neurosci 20:204-212.
39. Yang TT and Wang SJ (2009) Pyridoxine inhibits depolarization-evoked glutamate release in nerve terminals from rat cerebral cortex: a possible neuroprotective mechanism? J Pharmacol Exp Ther 331:244-254.
40. Yang ZJ, Carter EL, Torbey MT, Martin LJ, and Koehler RC (2010) Sigma receptor ligand 4-phenyl-1-(4-phenylbutyl)-piperidine modulates neuronal nitric oxide synthase/postsynaptic density-95 coupling mechanisms and protects against neonatal ischemic degeneration of striatal neurons. Exp Neurol 221:166-174.
41. Zhang H and Cuevas J (2002) Sigma receptors inhibit high-voltage- activated calcium channels in rat sympathetic and parasympathetic neurons. J Neurophysiol 87:2867-2879. (Pubitemid 34670667)
42. Zhang H and Cuevas J (2005) σ Receptor activation blocks potassium channels and depresses neuroexcitability in rat intracardiac neurons. J Pharmacol Exp Ther 313:1387-1396. (Pubitemid 40727046)
43. Zhang H, Katnik C, and Cuevas J (2009) Sigma receptor activation inhibits voltage-gated sodium channels in rat intracardiac ganglion neurons. Int J Physiol Pathophysiol Pharmacol 2:1-11.