Dietary chlorophyllin abrogates TGFβ signaling to modulate the hallmark capabilities of cancer in an animal model of forestomach carcinogenesis

Tumor Biology

Volumn 35, Issue 7, 2014, Pages 6725-6737

  Thiyagarajan, Paranthaman ^a   Kavitha, Krishnamurthy ^a   Thautam, Avaneesh ^b   Dixit, Madhulika ^b   Nagini, Siddavaram ^a  

^a ANNAMALAI UNIVERSITY   (India)

^b INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

Author keywords

Chemoprevention; Chlorophyllin; Hallmarks of cancer; MNNG; TGF

Indexed keywords

CASPASE 3; CASPASE 9; CELL PROTEIN; CHLOROPHYLL; CYCLIN D1; GELATINASE A; GELATINASE B; HYPOXIA INDUCIBLE FACTOR 1ALPHA; METHYLNITRONITROSOGUANIDINE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN P21; REVERSION INDUCING CYSTEINE RICH PROTEIN WITH KAZAL MOTIF; SMAD2 PROTEIN; SMAD4 PROTEIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL INVASION; CELL PROLIFERATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOWN REGULATION; FORESTOMACH; G1 PHASE CELL CYCLE CHECKPOINT; IMMUNOHISTOCHEMISTRY; MALE; METASTASIS; MITOCHONDRION; MOLECULAR DOCKING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; S PHASE CELL CYCLE CHECKPOINT; SIGNAL TRANSDUCTION; STOMACH CARCINOGENESIS; STOMACH CARCINOMA; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CARCINOGENESIS; CELL PROLIFERATION; CHLOROPHYLLIDES; DISEASE MODELS, ANIMAL; HUMANS; RATS; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84904988045     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-1849-5     Document Type: Article

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