Viral transduction of primary Schwann cells using a Cre-lox system to regulate GDNF expression

Biotechnology and Bioengineering

Volumn 111, Issue 9, 2014, Pages 1886-1894

  Wu Fienberg, Yuewei ^a   Moore, Amy M ^a   Marquardt, Laura M ^a,b   Newton, Piyaraj ^a   Johnson, Philip J ^a   Mackinnon, Susan E ^a   Sakiyama Elbert, Shelly E ^a,b   Wood, Matthew D ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY IN ST LOUIS   (United States)

Author keywords

Candy store effect; Cre lox; Drug delivery; Glial cell line derived neurotrophic factor; Lentivirus; Peripheral nerve

Indexed keywords

BIOACTIVITY; CELL CULTURE; DRUG DELIVERY; NEURONS;

CANDY-STORE EFFECT; CRE LOXES; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; LENTIVIRUS; PERIPHERAL NERVES;

GENE EXPRESSION;

CRE RECOMBINASE; DOXYCYCLINE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; LENTIVIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; GENE ACTIVATION; GENE DELETION; IMMUNOHISTOCHEMISTRY; INTERNAL RIBOSOME ENTRY SITE; LOXP SITE; MALE; NERVE FIBER; NERVE FIBER GROWTH; NERVE REGENERATION; NONHUMAN; PROTEIN EXPRESSION; RAT; REPORTER GENE; SCHWANN CELL; SIGNAL TRANSDUCTION; TISSUE ENGINEERING; VIRAL GENE DELIVERY SYSTEM; ANIMAL; BIOSYNTHESIS; CELL CULTURE; GENE EXPRESSION REGULATION; GENE VECTOR; GENETIC RECOMBINATION; GENETIC TRANSDUCTION; GENETICS; LENTIVIRINAE; LEWIS RAT; METABOLISM;

LENTIVIRUS;

ANIMALS; CELLS, CULTURED; GENE EXPRESSION REGULATION; GENETIC VECTORS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; LENTIVIRUS; RATS, INBRED LEW; RECOMBINATION, GENETIC; SCHWANN CELLS; TRANSDUCTION, GENETIC;

EID: 84904983995     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25247     Document Type: Article

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